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  4. Protein Analysis
  5. Other protein analysis
  6. Protein and Nucleic Acid Quality Evaluation Device 'STUNNER'

Protein and Nucleic Acid Quality Evaluation Device 'STUNNER'

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last updated:Sep 02, 2025

Unchained Labs (アンチェインドラブズ)
Unchained Labs (アンチェインドラブズ)
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Quality assessment of proteins, nucleic acids, AAV, LNP, etc. is possible with trace amounts and high throughput.

"Stunner" is a product that allows simultaneous acquisition of UV/Vis concentration, dynamic light scattering (DLS), and static light scattering (SLS) data from a 2μL identical sample. It enables detailed investigation of AAV and adenoviruses to measure total capsid titer and Empty/Full ratios, as well as to obtain payload concentration and size data of lipid nanoparticles all at once. You can analyze concentration, hydrodynamic size, polydispersity, and the presence of aggregates collectively, allowing you to assess the quality of proteins. This way, you can immediately determine whether your AAV, adenoviruses, lipid nanoparticles, or proteins are suitable for your purposes. [Features] ■ Measure up to 96 samples in a batch in 60 minutes*/12 minutes** *When measured by DLS **When measured by UV/Vis only [Applications] ■ AAV/Adenovirus capsid titer ■ AAV/Adenovirus Empty/Full ratio ■ Lipid nanoparticle (LNP) payload amount ■ Aggregate measurement ■ Concentration measurement ■ Sizing & polydispersity ■ B22 & kD *For more details, please refer to the PDF document or feel free to contact us.

    Other protein analysis
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Protein and Nucleic Acid Quality Evaluation Device 'STUNNER'

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  • Related Link - https://www.unchainedlabs.com/

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【Specifications (Excerpt)】 ■Dimensions: Width 37 cm, Depth 54 cm, Height 33 cm, Weight 26 kg ■Electrical Characteristics: Universal input voltage 100–240 V AC, 50–60 Hz ■Computer: Separate computer with Windows 10 ■Connection: USB, TCP/IP (Service) ■Approvals: CE, FCC, CSA ■Regulatory Compliance: Optional 21 CFR Part 11 software package *For more details, please refer to the PDF document or feel free to contact us.

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Protein quantification tool "Stunner"

Protein quantification tool "Stunner"

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Lipid Nanoparticle (LNP) Research Application Note vol.1

Lipid Nanoparticle (LNP) Research Application Note vol.1

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Lipid Nanoparticle (LNP) Research Application Note vol.2

Lipid Nanoparticle (LNP) Research Application Note vol.2

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Accuracy of UV/Vis in Lunatic and Stunner

Accuracy of UV/Vis in Lunatic and Stunner

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Performance evaluation according to the US and European Pharmacopoeia for UV/Vis Lunatic/Stunner

Performance evaluation according to the US and European Pharmacopoeia for UV/Vis Lunatic/Stunner

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Measurement of adenovirus titer and characterization using Stunner.

Measurement of adenovirus titer and characterization using Stunner.

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Stunner Paper Publication List

Stunner Paper Publication List

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Let's count, size, and quantify RNA with Stunner using LNP.

Let's count, size, and quantify RNA with Stunner using LNP.

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AAV Research Application Note

AAV Research Application Note

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[Application Note] Accelerating LNP Product Development with Sun Series at Lightning Speed

[Application Note] Accelerating LNP Product Development with Sun Series at Lightning Speed

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Let's speed up and simplify the prescription screening with Big Tuna and Stunner.

Let's speed up and simplify the prescription screening with Big Tuna and Stunner.

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◆On-Demand Webinar Distribution◆ A Ray of Hope for Challenges in LNP Research and Development

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The development of lipid nanoparticles (LNP) requires flexible tools that can accommodate everything from screening to GMP manufacturing. The ideal manufacturing equipment should be capable of handling a wide range of applications, from small-scale, easy-to-handle experiments to multi-parameter, multi-sample, large-scale continuous operations. Additionally, not only is the production of LNP important, but the evaluation of characteristics such as encapsulation efficiency (EE%), RNA amount, particle size, and PDI is also crucial; traditionally, these measurements have been complicated and required multiple instruments. In this webinar, we will introduce scalable LNP manufacturing by Sunshine and one-stop measurements of EE%, total RNA, particle size, PDI, and particle concentration using Stunner AF. Furthermore, you will also be able to watch a demo video showcasing the actual operation of the Sun series (Sunshine, Sunscreen) and Stunner! Instructor: Takuma Iwasaki | Field Application Scientist *This webinar is a recording of a session hosted by Unchained Labs, Inc. in October 2025.

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We will exhibit at the 4th Annual Meeting of the Japanese Society for Antibody Research.

  • Seminar・Event

Unchained Labs, Inc. will be exhibiting at the 4th Annual Meeting of the Japanese Society for Antibody Research, which will be held from December 1 (Monday). At our booth, we will introduce innovative tools essential for antibody and ADC research, such as Aunty, a device for evaluating protein structural stability, and Stunner, which can measure various parameters including potency and size. We look forward to seeing you in Omiya! Exhibition details: ■ Dates: December 1 (Monday) to 3 (Wednesday), 2025 ■ Venue: Omiya Sonic City

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[Free Webinar] Making mAb and ADC Characterization Smarter

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The analysis of antibodies and antibody-drug conjugates (ADCs) is no longer a headache. Stunner measures the concentration, size, and aggregation of antibodies using just 2 µL of sample in 2 minutes, processing up to 96 samples in a single run. In this webinar, we will detail how Stunner's Unmix software separates the signals of antibodies and drugs, allowing for the rapid quantification of protein amount, drug amount, and drug-antibody ratio (DAR). Be sure to see how Stunner streamlines the cumbersome ADC characterization process.

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[Free Webinar] Bringing Hope to the Challenges of LNP Research and Development, Sunshine Series & Stunner AF

  • Seminar・Event

The development of lipid nanoparticles (LNPs) requires flexible tools that can consistently handle everything from screening to GMP manufacturing. An ideal manufacturing tool must accommodate small-scale, user-friendly experiments as well as multi-parameter, multi-sample, and even large-scale continuous operations. However, the creation of lipid nanoparticles (LNPs) is only half the goal; evaluating characteristics such as encapsulation efficiency (EE%), payload quantification, particle size, and PDI is also essential. Our Sunshine series and Stunner AF (Add Fluorescence) enable scalable nanoparticle manufacturing and powerful all-in-one characterization. In this webinar, we will introduce scalable LNP manufacturing with Sunshine and one-stop measurements of EE%, total RNA quantification, particle size, PDI, and particle concentration with Stunner AF. Experience solutions that will take nanoparticle development to the next level, from research to industrial applications.

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Unchained

Unchained Labs (アンチェインドラブズ)

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Unchained Labs is a company headquartered in Silicon Valley, California, that provides next-generation life science tools. - A lineup of automation devices for biopharmaceutical research, gene therapy, and organic synthesis - Founded in 2015 - Locations in California, New Jersey, Boston, the UK, Brussels, Germany, Shanghai, and Japan - Established a Japanese subsidiary in July 2017

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