[Free Webinar] Bringing Hope to the Challenges of LNP Research and Development, Sunshine Series & Stunner AF

Quality assessment of proteins, nucleic acids, AAV, LNP, etc. is possible with trace amounts and high throughput.

"Stunner" is a product that allows simultaneous acquisition of UV/Vis concentration, dynamic light scattering (DLS), and static light scattering (SLS) data from a 2μL identical sample. It enables detailed investigation of AAV and adenoviruses to measure total capsid titer and Empty/Full ratios, as well as to obtain payload concentration and size data of lipid nanoparticles all at once. You can analyze concentration, hydrodynamic size, polydispersity, and the presence of aggregates collectively, allowing you to assess the quality of proteins. This way, you can immediately determine whether your AAV, adenoviruses, lipid nanoparticles, or proteins are suitable for your purposes. [Features] ■ Measure up to 96 samples in a batch in 60 minutes*/12 minutes** *When measured by DLS **When measured by UV/Vis only [Applications] ■ AAV/Adenovirus capsid titer ■ AAV/Adenovirus Empty/Full ratio ■ Lipid nanoparticle (LNP) payload amount ■ Aggregate measurement ■ Concentration measurement ■ Sizing & polydispersity ■ B22 & kD *For more details, please refer to the PDF document or feel free to contact us.

• Other protein analysis

Introducing the details of the newly launched LNP production and screening device.

Researchers of lipid nanoparticles (LNPs) spend a tremendous amount of time on screening, optimization, and scaling up experiments to achieve optimal performance, spot-on targeting, and controlled release of active pharmaceutical ingredients (APIs). Factors such as solubility, pH stability, payload release, and encapsulation all depend on particle size, shape, and structure. In other words, to obtain the right formulation, it is necessary to explore a vast number of formulation parameters and process parameters one by one, and even if a perfect formulation is found, scaling up usually means switching equipment and re-optimizing settings. In this webinar, we will introduce a platform, Sunny Suite, that can reduce the time spent on these LNP formulations. ■ Date and Time: February 26 (Monday) 14:00~ ■ Speaker: Yuji Senoo, Field Application Scientist, Unchained Labs, Inc. ■ Register here: https://unchainedlabs.zoom.us/webinar/register/3217065146675/WN_U1o3xQoZRAKHN-A-7b1yqg

• Other protein analysis

Seamlessly transition from formulation condition screening to scale-up and GMP manufacturing. Accelerate LNP product development.

The development of lipid nanoparticles (LNPs) faces many challenges. The formulation, optimization, and scale-up for clinical trials are complex, costly, and a race against time. Our LNP solutions are designed to accelerate all steps of LNP synthesis and characterization. Sunscreen accelerates LNP formulation screening by reducing costs and time, generating up to 96 unique LNP formulations within 6 hours. Next, using Sunshine, you can develop, optimize, and scale up protocols with the appropriate formulations obtained from Sunscreen. When it comes to the clinical trial phase, Sunbather can accommodate LNP production in a GMP environment using the same processes and microfluidic chips (Sunny) utilized by Sunscreen and Sunshine. In this way, the Sun series allows for a seamless transition from screening formulation conditions to scale-up and GMP manufacturing, as they all use the same pumps and microchannel chips. *For product details, please download various materials.

• Other Physics and Chemistry Equipment

Accelerating formulation optimization for vaccine and pharmaceutical development.

The transition from LNP to GMP is a costly and complicated process. Typically, this requires switching equipment, using different flow paths and mixing devices, and essentially re-developing and re-validating everything that has been painstakingly done so far. With Sunbather, the transition to GMP can be done easily thanks to its recording features, interchangeable flow paths, and easily transferable design. Sunbather uses the same mixing process and protocols as the Sunscreen and Sunshine from the same Sun series, allowing for easy transition of adjusted formulation conditions to GMP. - Up to 1.8 L/h - Integrated inline dilution - Fully interchangeable flow paths - A wide variety of mixing devices - Software compliant with 21 CFR Part 11 - Process transferable from Sunshine

• Other Physics and Chemistry Equipment

Efficient mass production of LNPs - Supporting everything from small-scale condition testing to scale-up.

Once we succeed in finding the optimal formulation conditions for sunscreen, let's use Sunshine to adjust the size of the LNP. Furthermore, we will optimize the protocols and processes for scaling up. We will find the ideal flow rate and explore different mixing options. Next, we will adjust these to the appropriate dilution factor that can keep them stable. Once everything is in place, Sunshine will transition to continuous mode, allowing us to produce several dozen liters in a day. In other words, we will achieve process development and scaling up on a single platform. Many researchers have likely been looking forward to the birth of such a groundbreaking system. • 10 experiments in 15 minutes • Fraction & total flow • From 1 mL to continuous flow • Flow rate 0.1 to 30 mL/min • Reusable microfluidic chips • Possible transition of protocols from sunscreen

• Other Physics and Chemistry Equipment

Accelerating formulation optimization for vaccine and pharmaceutical development.

To create the optimal LNP, it takes a tremendous amount of time and effort to examine and pursue formulation conditions. LNPs are nanoparticles composed of multiple lipids. Therefore, it is necessary to find the optimal conditions such as the mixing ratios, the ratio of lipids to payload, and the flow rates during mixing. Furthermore, we must also consider throughput issues. Sunscreen can produce up to 96 types of small LNPs within six hours, thus solving the previous throughput problems. This means that it is possible to explore a greater number of formulation condition investigations in a single day. • Fully automated execution of up to 96 types of condition investigations within six hours • 200 μL to 2 mL per experiment • Flow rate of 0.1 to 30 mL/min • Reusable microfluidic chips • Seamless scale-up through process and protocol optimization

• Other Physics and Chemistry Equipment

Nitto Kohki will hold the "2025 Attack Fair in Meiko" for two days from July 23 (Wednesday) to July 24 (Thursday), 2025, at the "Kowa Seminar Plaza 2F Training Room NO.12 (inside Kowa Sports Land)." The Attack Fair is an exhibition where you can actually "see, touch, and operate" Nitto Kohki's products. Additionally, there will be wonderful souvenirs for attendees and many fun activities planned. We look forward to welcoming everyone!

The "Building Maintenance Human Fair & Clean EXPO 2025," which will be held from November 19 (Wednesday) to 21 (Friday), 2025, is an annual exhibition specializing in the building maintenance field, organized by the National Building Maintenance Association and the Japan Management Association. The field reporting app "Smart Attack" is celebrating its 15th anniversary this year since its release. It has a proven track record of being used by many customers as an efficiency tool for various building maintenance tasks such as cleaning, security, and facility management! At our exhibition booth, we will present a demonstration and the latest information about the completely renewed new app "Smart Attack V3." ★★★ Points ★★★ Fully renewed version: New app "Smart Attack V3" The fully renewed version of the new app "Smart Attack" is here! You can see the latest version "Smart Attack V3," which has improved processing speed and a completely revamped design, in a demonstration. All of us at the company look forward to your visit.

Naviace Co., Ltd. will be exhibiting at the "39th Hokkaido Technology and Business Exchange Meeting" business expo held in Sapporo, Hokkaido (https://www.business-expo.jp/). Under the theme "Change Challenges into Strengths with Carbon Neutrality!!", we will showcase our environmentally friendly cardboard pallet, "Navi Pallet". <Product Features> - Lightweight and high load capacity to improve work efficiency - 100% recyclable and ideal for one-way operations - No heat treatment required, making it suitable for export - High design flexibility for adaptable solutions - Contributes to addressing the logistics 2024 problem and reducing CO₂ emissions The Navi Pallet not only supports the transition from manual loading and unloading to palletization but also contributes to achieving carbon neutrality. We will also display actual Navi Pallets that have been implemented at the venue. Please come and experience the "strength" and "lightness" for yourself. Exhibition Area: Sapporo Chamber of Commerce and Industry Manufacturing Corner

Techne Measurement Co., Ltd. will be exhibiting at the 66th Battery Discussion Conference, which will be held at Wink Aichi from November 18 (Tuesday) to November 20 (Thursday), 2025. This time, we will showcase dew point meters and low dew point calibrators for the battery industry. Please be sure to visit the Techne Measurement booth.

As global inter-company competition intensifies, there is a growing demand for the investigation and analysis of foreign patents. However, due to language barriers and the vast amount of patent information available, it is challenging to search for only relevant technologies, necessitating advanced research skills to conduct efficient investigations. In response, we would like to introduce our patent research support service "PatentSQUARE," which allows you to learn the basics to advanced applications of foreign patent investigations, along with useful features and the latest functionalities. ≪Part One: Recommended for Those Who Are Starting Foreign Patent Investigations≫ - Unique input methods for specific conditions when searching foreign literature - How to conduct investigations with an awareness of patent families - Equipped with an English company name dictionary to support the resolution of discrepancies in notation during analysis ≪Part Two: Recommended for Those Who Want to Analyze Foreign Patents or Conduct Research in New Areas and Competitors≫ - Convenient ways to utilize AI searches to overcome the question of where to start - Practical methods for creating a parent set, analyzing it, and utilizing the information afterward - What can be done "because" of the IP BI dashboard If you want to improve the efficiency of foreign patent investigations or easily conduct analyses of domestic and foreign patents, please feel free to join us. *You can participate in only the themes you prefer.