The "Sun Series" that covers the development of lipid nanoparticles from upstream to downstream.

The development of lipid nanoparticles (LNPs) requires flexible tools that can consistently handle everything from screening to GMP manufacturing. An ideal manufacturing tool must accommodate small-scale, user-friendly experiments as well as multi-parameter, multi-sample, and even large-scale continuous operations. However, the creation of lipid nanoparticles (LNPs) is only half the goal; evaluating characteristics such as encapsulation efficiency (EE%), payload quantification, particle size, and PDI is also essential. Our Sunshine series and Stunner AF (Add Fluorescence) enable scalable nanoparticle manufacturing and powerful all-in-one characterization. In this webinar, we will introduce scalable LNP manufacturing with Sunshine and one-stop measurements of EE%, total RNA quantification, particle size, PDI, and particle concentration with Stunner AF. Experience solutions that will take nanoparticle development to the next level, from research to industrial applications.

**[Issue]** The evolution of LNPs is progressing more rapidly than ever, largely due to modifications in particle formulations. However, the formulations to be tested are complex in composition and involve a vast number of combinations, making large-scale screening difficult to achieve. Furthermore, there is the subsequent challenge of transferring to production. Evaluations are also required to be accurate, comprehensive, and high-throughput. **[Webinar Overview]** In this webinar, we will explain how our Sun series can accelerate the exploration and development of LNPs, based on the latest research findings and user case studies in LNP formulations. We will also introduce Stunner, which enables high-speed and accurate LNP evaluations.

CPhI Japan Exhibition & Seminar! April 9 (Wednesday) - 11 (Friday) @ Tokyo Big Sight Unchained Labs, Inc. will be exhibiting in the biopharmaceutical zone at CPhI Japan this year as well. Additionally, we will hold a seminar on the second day! Please visit our booth at Tokyo Big Sight. <Exhibitor Seminar> Date and Time: April 10 (Thursday) 13:00-13:30 Venue: 5B "Stability Evaluation of Biopharmaceuticals - Towards a New Era of High-Speed and High-Throughput" *No prior reservation required, free of charge.

<Announcement of Interphex Exhibition and Product Technology Seminars> Our company will be exhibiting at the Interphex BioPharmaceuticals EXPO again this year. Additionally, we will be presenting at product technology seminars on the first and second days of the exhibition! We invite you to come to Tokyo Big Sight. Exhibition Details: Name: Interphex Week Tokyo (26th Edition) Date: June 26 (Wednesday) - 28 (Friday), 2024 Venue: Tokyo Big Sight Booth: 46-17 (East Hall 6), diagonally across from Cytiva's booth Product Technology Seminar 1 "Solutions for Completely Mastering Lipid Nanoparticles (LNP)" ● June 26 (Wednesday) 11:40 - 12:10 ● Venue: Exhibitor Seminar Room 6 (East Hall 5) Product Technology Seminar 2 "How to Achieve Automation in Chemical Research" ● June 27 (Thursday) 12:30 - 13:00 ● Venue: Exhibitor Seminar Room 7 (East Hall 6)