Cutting just below the hinge region of mouse IgG! There is no risk of over-digestion due to the high specificity of the enzyme!
"FabRICATOR Z (IdeZ)" is a cysteine protease that cleaves specific sites downstream of the hinge region of mouse IgG2a and IgG3, generating a homogeneous pool of F(ab')2 and Fc fragments after 2 hours of incubation. Some mouse IgG2a that cannot be digested by FabRICATOR can be easily digested with this product, although a longer incubation time may be required. Additionally, due to the high specificity of the enzyme, there is no risk of over-digestion. 【Features】 ■ Cleaves specific sites downstream of the hinge region of mouse IgG2a and IgG3 ■ Generates a homogeneous pool of F(ab')2 and Fc fragments after 2 hours of incubation ■ Some mouse IgG2a can be easily digested ■ No risk of over-digestion due to the high specificity of the enzyme *For more details, please refer to the PDF document or feel free to contact us.
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【Product Format】 ■FragIT Z: A product with enzymes immobilized on a spin column ■FabRICATOR Z: Freeze-dried enzymes ■FragIT Z kit: A set of FragIT and CaptureSelect (Fc fragment purification column) *For more details, please refer to the PDF materials or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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Rohmatsu Trading Co., Ltd. engages in the procurement, research, and contracting of overseas chemical products, as well as providing information on them. From the top management to all employees, we unite as one, always keeping five keywords in mind, continuously striving for creativity and ingenuity, and serving the market to contribute to society.