Cleavage of the upper region of the human IgG1 hinge! Produces intact and homogeneous Fab and Fc fragments.
"GingisKHAN (Kgp)" is a cysteine protease that cleaves human IgG1 at a specific site upstream of the hinge region, producing intact and homogeneous Fab and Fc fragments. This enzyme is used for the characterization of antibody-based biological therapies using LC-MS, Fc glycan analysis, studies on the effects of bispecific antibodies, affinity and binding strength, as well as the identification of post-translational modifications. [Features] - Cleaves human IgG1 at a specific site upstream of the hinge region - Produces intact and homogeneous Fab and Fc fragments - Used for the characterization of antibody-based biological therapies using LC-MS, Fc glycan analysis, studies on the effects of bispecific antibodies, affinity and binding strength, and the identification of post-translational modifications *For more details, please refer to the PDF document or feel free to contact us.
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【Product Format】 ■GingisKHAN: Freeze-dried enzyme ■GingisKHAN Fab kit A set of freeze-dried enzyme and CaptureSelect CH1 (Fab fragment purification column) *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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Rohmatsu Trading Co., Ltd. engages in the procurement, research, and contracting of overseas chemical products, as well as providing information on them. From the top management to all employees, we unite as one, always keeping five keywords in mind, continuously striving for creativity and ingenuity, and serving the market to contribute to society.