Publication on the prospects of preventive and therapeutic vaccines, including the synthesis of α-GalCer compound (KRN7000)!
This document introduces the prospects of a preventive and therapeutic vaccine using KRN7000 (a-galactosylceramide: a-GalCer). It includes topics such as "The history of the discovery of the natural compound a-galactosylceramide," "Synthesis of the a-GalCer compound (KRN7000)," and "Mechanism of action of a-GalCer." We encourage you to read it. 【Contents】 ■ The history of the discovery of the natural compound a-galactosylceramide (α-GalCer) ■ Synthesis of the a-GalCer compound (KRN7000) ■ Mechanism of action of a-GalCer ■ Immunostimulatory effects of a-GalCer and its application in cancer treatment ■ Immunoregulatory effects of a-GalCer and its application in the treatment of allergies, autoimmune diseases, and suppression of transplant rejection *For more details, please refer to the PDF document or feel free to contact us.
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basic information
KRN7000GMP Sales Related α-galactosylceramide α-GalCer α-galactosylceramide NKT Dendritic cell KRN7000 DC Dendritic cell *For more details, please refer to the PDF document or feel free to contact us.*
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Applications/Examples of results
For more details, please refer to the PDF document or feel free to contact us.
Detailed information
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Case of DC therapy using KRN7000
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Comparison of IFN-γ production levels
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Company information
At Axelvex, we provide advanced medical support such as therapeutic cell processing. In recent years, the progress in cancer immunotherapy has been remarkable, with an increasing number of new approaches that control the immune function in the body through molecular targeted therapies like antibody drugs and checkpoint inhibitors. The self-tumor cell vector "SynVC," developed with our technology, can present all the cancer antigens possessed by the patient's own cancer cells and tissues to the immune cells in the patient's body, allowing for the acquisition and memory of immunity specific to the cancer antigens.
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