We are continuously developing new products while also focusing on the collection of safety data!
We are seeking research ideas for nasal mucosa studies using animal models. Currently, we are employing a method where a tube is inserted through either the right or left nasal cavity of rodent animal models to deliver liquid, while creating negative pressure in the opposite nasal cavity to collect the liquid. However, it seems that rodents, which cannot breathe through their mouths, are more likely to have liquids that enter through the nose reach their lungs, and due to the weakness caused by continuous washing, it has become difficult to evaluate the safety of long-term use. Therefore, we have decided to seek solutions to this issue from researchers in a wide range of fields dealing with animal models. If you have research ideas using animal models that can evaluate the safety of nasal cleansing products during continuous washing, please submit your proposals through the Innovation Portal linked below. *For more details, please refer to the PDF document or feel free to contact us.
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**Desired Technology** ■ Ability to evaluate the safety of nasal irrigation products through continuous washing in vivo - Assuming more than 21 washings (3 times/day × 7 days) - Preferably using rodents due to the abundance of back data on nasal mucosa - Also considering primates and dogs, but small animals that are easier to handle are preferred - If nasal cavity epithelial cells or mucosal cells cultured in layers can replicate the nasal cavity environment, they will also be considered even if not in vivo **Technologies Not Considered** ■ Technologies evaluated through in vitro or human clinical trials **Expected Partners** ■ Researchers in the fields of nasal mucosa and allergies who work with animal models ■ Researchers skilled in creating and utilizing animal models ■ Researchers in alternative methods to animal testing *For more details, please refer to the PDF document or feel free to contact us.*
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For more details, please refer to the PDF document or feel free to contact us.
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Our company, yet2com, is an expert in connecting open innovation (OI) to corporate innovation in line with our clients' business growth strategies. Founded in 1999 in Boston, USA (yet2.com Inc.), we have been providing OI services to manufacturers around the world for over 20 years. We have a proven track record of over 10 years in conducting technology research for not only corporations but also U.S. government agencies. With our solid services and methodologies, we lead client companies to successful open innovation. If you are wondering what kind of research is progressing in this technological field, whether there are materials with such characteristics, or if there are other applications for a newly developed material intended for a specific purpose, please feel free to contact us.
