This product has successfully achieved miniaturization using a manufacturing method called Amarga, developed by Xidas Corporation.
Dielectrophoresis (DEP) is a method that utilizes a high-intensity alternating electric field gradient to sort small particles, such as cells, based on their dielectric properties. Cells that exhibit a specific polarity are attracted to (or repelled by) the electric field gradient. As these cells flow through the stream, they deviate from the main flow, allowing them to be removed or collected for future use. XIDAS manufactures highly robust and efficient DEP flow cell products (patent pending) that enable the easy introduction of heterogeneous cell populations and allow for their sorting as they flow through the flow cell. XIDAS's DEP devices use three-dimensional floating electrodes to generate the maximum electric field gradient at the center of the flow stream. Additionally, the design of the flow cell can ensure that cells are maximally exposed to the electric field. A common application of DEP sorting is to eliminate dead cells and concentrate viable cell samples.
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basic information
Features - Robust and sturdy fluid design - High-performance design using suspended electrodes for maximum electric field gradient - Long flow path and interaction length - Easy coupling with tubes and electrical signals - Supports high volumetric flow rates (milliliters/minute) - Flow focusing is not required (for some models) - Custom flow path sizes and materials available o Rigid polymer or PDMS o Channel dimensions up to 100 µm - For other options, please contact XIDAS. Accessories - Programmable high-voltage power supply, up to 1 MHz at 100V - DEP calibration device (for observing and testing DEP conditions) - Flow control system - Flow cell testing device (for non-electrode, flow state testing) Model number: DEP-01-284-512-P0-x This is a flow cell using dielectrophoresis with built-in suspended electrodes. It is robust and user-friendly, capable of providing a high electric field gradient at the center of the flow path. Additionally, a high-voltage power supply for driving DEP devices is also provided.
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Applications/Examples of results
Cell research, drug discovery, diagnostic applications for cancer, etc.
Company information
In the world of microtechnology, the evolution of IoT has created demand, and the enduring semiconductor MEMS industry has begun to face design limitations. Professor Mark Bachman from the University of California, Irvine (UCI) has invented more innovative solutions through 20 years of developing miniaturized mechanical technology. With a vision to spread this technology worldwide, Professor Bachman teamed up with industry entrepreneur Paul Dillon and former Cadence and AWR president James Spott to establish Integra Devices (now Xidas) on the UCI campus.
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