Regenerative Medicine Creative Experience Lab (T-CEL)

basic information

Lab Area You can view the equipment necessary for research and development and manufacturing processes of cell therapy and gene therapy products, organized by workflow. Lab Design Area You can design a lab in a virtual space on a dedicated application. Single-Use Product Introduction Area You can physically handle and view important single-use products used in the pharmaceutical manufacturing process. We provide information on the shape, size, and material of the products, as well as their usability and compatibility with other products. We assist in designing your manufacturing process. Contract Manufacturing (CDMO) Service Introduction Area We will introduce our contract manufacturing services, including future options for commercial production, based on case studies. Through discussions with customers, we will propose suitable solutions. Seminars & Hands-On Training Our experts conduct seminars and training sessions regularly. We also contribute to the development of human resources in the regenerative medicine field through our solutions.

Price range

Delivery Time

Applications/Examples of results

Recommended for the following customers: • Those researching and developing regenerative medicine products • Those planning to manufacture regenerative medicine products in the future • Those who want to learn about the manufacturing workflow for cell therapy and gene therapy • Those planning new setups or expansions of labs, CPCs, or manufacturing facilities • Those considering contract pharmaceutical manufacturing and the supply chain for clinical trial drugs Examples of seminars: • Delivering CAR-T cell therapy to market faster – Research, manufacturing, and storage/transport solutions • Upstream processes in viral vector production and techniques for evaluating residual DNA from HEK293 • Hands-on training for mycoplasma detection testing • Proper use of laboratory equipment • Lab Products Virtual Tools lab design training

Detailed information

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  The Thermo Scientific Forma Steri-Cycle CR CTS series CO2 incubator is a CO2 incubator designed for cell and gene therapy manufacturing workflows, compliant with clean room environments of ISO Class 5. It features a patent-pending particle control system that suppresses particles generated from the equipment itself, ensuring no impact on the clean room environment. In addition to a standard data output port, it is constructed with a stainless steel case that is resistant to decontaminants containing strong oxidizers.

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  The Thermo Scientific Herasafe 2030i is the latest model of the Class II Type A2 safety cabinet that further develops the design of the globally acclaimed legacy Herasafe models, merging comfortable operability and information management functions without compromising the safety of "samples," "operators," and "facilities and surrounding environments." It also supports customization options such as back panel mounting for particle counter cups and cameras/monitors. The accessory stool features an ergonomic design that helps maintain a posture that reduces fatigue during long hours of work.

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  The Thermo Scientific Sorvall X4 Pro series high-performance universal centrifuge features a large capacity and a wide range of rotor sets. It is suitable for the recovery of several liters of cells required in the manufacturing of cell and gene therapies. By simply swapping adapters, you can utilize a large-capacity swing rotor that allows for the centrifugation of bottles, plates, and blood bags, and there are also plenty of accessories available, such as bucket lids that comply with biosafety standards. Additionally, you can upgrade to the SECURE-Spin mode, which provides a log data management function to record "when," "who," and "under what conditions" the centrifugation was performed.

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  The Gibco CTS Rotea Counterflow Centrifugation System is a highly flexible, closed-system automated cell processing system that minimizes cell damage. This versatile system allows for the creation and optimization of a wide range of cell processing protocols tailored to specific purposes and applications, such as cell separation, washing, and concentration. Additionally, the gentle processing method achieves high cell recovery rates and cell viability. In addition to its compact size, flexible processes, and closed-system single-use kits, it enables the seamless transition of protocols developed during research and development to commercial production.

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  The Gibco CTS Xenon Electroporation System, which streamlines cell therapy development, features a flexible and closed-system electroporation setup that enables rapid and efficient transfection with minimal impact on cell viability and recovery. With a programmable interface, flexible operability, and the use of sterilized single-use consumables compatible with 1 mL or 5–25 mL large volumes, the system allows for smooth scale-up of cell therapy workflows from process development to clinical manufacturing, supported by software upgrades that comply with 21 CFR Part 11.

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  The Thermo Scientific DynaDrive Single-Use Bioreactor (S.U.B.) is a new innovation in single-use bioreactors. The traditional HyPerforma bioreactor was launched in 2006 and has continued to succeed steadily after being updated in 2013. The DynaDrive single-use bioreactor features a new design that offers performance and scalability for large capacities of 3000 L and 5000 L, exceeding 2000 L. It possesses excellent cell culture performance at all scales and enables high-density cultivation.

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  The demand for innovative single-use harvest solutions that cater to the production of recombinant proteins, monoclonal antibodies (mAb), and bioengineering vaccines continues to rise. As the need for process efficiency and optimization increases, the Thermo Scientific DynaSpin single-use continuous centrifuge offers a beneficial single-use recovery solution that achieves excellent separation performance automation, adding significant value to pharmaceutical manufacturing.

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  The Thermo Scientific Sorvall BIOS 16 ultra-large capacity refrigerated centrifuge is a bioprocess-specific model featuring an unparalleled capacity of up to 16 L (8 x 2 L) for centrifugation. It can centrifuge 2 L to 500 mL centrifuge bottles, and by using adapters, high-throughput centrifugation of 50 mL and 15 mL conical tubes and blood collection tubes is also possible. Furthermore, it can utilize the Thermo Scientific CentriPAK BPC centrifuge bags, which allow for filling, centrifugation, and recovery in blood bags and closed systems. Optionally, it can connect to log management software that records "when," "who," and "under what conditions" runs were executed, making it suitable for workflow construction in a cGMP environment.

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  The Gibco CTS DynaCellect Magnetic Separation System is a groundbreaking closed-system cell separation system that automates the processes of cell separation, activation, and bead removal using magnets in the development and manufacturing of cell therapies. Designed for use with magnetic beads, it demonstrates excellent performance in cell recovery, purity, high throughput, and process flexibility. Furthermore, it accommodates various process scales from research to the manufacturing of clinical trial drugs without compromising cell viability.