Single-cell interaction cytometry heliXcyto
heliXcyto Biosensor
A new measurement method that enables real-time interaction analysis on cells!
heliXcyto, which employs the Single Cell Interaction Cytometry (scIC) method that combines the biophysical measurement principles of biosensors with cytometry, enables the automatic analysis of binding constants (affinity, avidity) while maintaining the complexity of biological systems by directly measuring the kinetics of molecular binding and dissociation on the cell surface.
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basic information
At heliXcyto, a newly designed cellTRAP biochip with a cage made of biocompatible polymer captures various types of single cells on the chip and directly measures the association rate constant kon and dissociation rate constant koff through real-time interaction measurements on the cell surface.
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P8
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Applications/Examples of results
Various possibilities in cancer immunology and cell therapy! Kinetic analysis of interactions of multivalent antibodies and other biopharmaceuticals on cells. Kinetic analysis of interactions of cell surface receptors (such as GPCRs) that have been difficult to analyze until now.
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Company information
DKSH is a member of the Swiss global company "DKSH Group." It provides comprehensive services and solutions across the entire value chain, combining procurement, marketing, sales, distribution, and after-sales service, through its three business divisions: consumer goods, production materials, and technology, with a long-term perspective.
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