iPROS Manufacturing
  • Search for products by classification category

    • Electronic Components and Modules
      Electronic Components and Modules
      60048items
    • Machinery Parts
      Machinery Parts
      74947items
    • Manufacturing and processing machinery
      Manufacturing and processing machinery
      100600items
    • Scientific and Physics Equipment
      Scientific and Physics Equipment
      35566items
    • Materials
      Materials
      37318items
    • Measurement and Analysis
      Measurement and Analysis
      55139items
    • Image Processing
      Image Processing
      15218items
    • Control and Electrical Equipment
      Control and Electrical Equipment
      53539items
    • Tools, consumables, and supplies
      Tools, consumables, and supplies
      64609items
    • Design and production support
      Design and production support
      12480items
    • IT/Network
      IT/Network
      44160items
    • Office
      Office
      13849items
    • Business support services
      Business support services
      24503items
    • Seminars and Skill Development
      Seminars and Skill Development
      6419items
    • Pharmaceutical and food related
      Pharmaceutical and food related
      31409items
    • others
      74176items
  • Search for companies by industry

    • Manufacturing and processing contract
      7335
    • others
      5010
    • Industrial Machinery
      4411
    • Machine elements and parts
      3282
    • Other manufacturing
      2879
    • IT/Telecommunications
      2557
    • Trading company/Wholesale
      2472
    • Industrial Electrical Equipment
      2301
    • Building materials, supplies and fixtures
      1816
    • software
      1631
    • Electronic Components and Semiconductors
      1565
    • Resin/Plastic
      1493
    • Service Industry
      1451
    • Testing, Analysis and Measurement
      1127
    • Ferrous/Non-ferrous metals
      982
    • environment
      697
    • Chemical
      630
    • Automobiles and Transportation Equipment
      560
    • Printing Industry
      509
    • Information and Communications
      456
    • Consumer Electronics
      417
    • Energy
      329
    • Rubber products
      312
    • Food Machinery
      306
    • Optical Instruments
      276
    • robot
      272
    • fiber
      250
    • Paper and pulp
      229
    • Pharmaceuticals and Biotechnology
      167
    • Electricity, Gas and Water Industry
      167
    • Warehousing and transport related industries
      146
    • Glass and clay products
      140
    • Food and Beverage
      128
    • CAD/CAM
      123
    • retail
      109
    • Medical Devices
      103
    • Educational and Research Institutions
      101
    • Ceramics
      98
    • wood
      88
    • Transportation
      82
    • Petroleum and coal products
      62
    • Medical and Welfare
      62
    • Shipbuilding and heavy machinery
      51
    • Aviation & Aerospace
      47
    • Fisheries, Agriculture and Forestry
      41
    • equipment
      32
    • Public interest/special/independent administrative agency
      31
    • Materials
      25
    • self-employed
      24
    • Research and development equipment and devices
      24
    • Government
      23
    • Mining
      17
    • Finance, securities and insurance
      13
    • cosmetics
      12
    • Individual
      10
    • Restaurants and accommodations
      9
    • Police, Fire Department, Self-Defense Forces
      7
    • Raw materials for reagents and chemicals
      3
    • Laboratory Equipment and Consumables
      3
    • Contracted research
      3
  • Special Features
  • Ranking

    • Overall Products Ranking
    • Overall Company Ranking
Search for Products
  • Search for products by classification category

  • Electronic Components and Modules
  • Machinery Parts
  • Manufacturing and processing machinery
  • Scientific and Physics Equipment
  • Materials
  • Measurement and Analysis
  • Image Processing
  • Control and Electrical Equipment
  • Tools, consumables, and supplies
  • Design and production support
  • IT/Network
  • Office
  • Business support services
  • Seminars and Skill Development
  • Pharmaceutical and food related
  • others
Search for Companies
  • Search for companies by industry

  • Manufacturing and processing contract
  • others
  • Industrial Machinery
  • Machine elements and parts
  • Other manufacturing
  • IT/Telecommunications
  • Trading company/Wholesale
  • Industrial Electrical Equipment
  • Building materials, supplies and fixtures
  • software
  • Electronic Components and Semiconductors
  • Resin/Plastic
  • Service Industry
  • Testing, Analysis and Measurement
  • Ferrous/Non-ferrous metals
  • environment
  • Chemical
  • Automobiles and Transportation Equipment
  • Printing Industry
  • Information and Communications
  • Consumer Electronics
  • Energy
  • Rubber products
  • Food Machinery
  • Optical Instruments
  • robot
  • fiber
  • Paper and pulp
  • Pharmaceuticals and Biotechnology
  • Electricity, Gas and Water Industry
  • Warehousing and transport related industries
  • Glass and clay products
  • Food and Beverage
  • CAD/CAM
  • retail
  • Medical Devices
  • Educational and Research Institutions
  • Ceramics
  • wood
  • Transportation
  • Petroleum and coal products
  • Medical and Welfare
  • Shipbuilding and heavy machinery
  • Aviation & Aerospace
  • Fisheries, Agriculture and Forestry
  • equipment
  • Public interest/special/independent administrative agency
  • Materials
  • self-employed
  • Research and development equipment and devices
  • Government
  • Mining
  • Finance, securities and insurance
  • cosmetics
  • Individual
  • Restaurants and accommodations
  • Police, Fire Department, Self-Defense Forces
  • Raw materials for reagents and chemicals
  • Laboratory Equipment and Consumables
  • Contracted research
Special Features
Ranking
  • Overall Products Ranking
  • Overall Company Ranking
  • privacy policy
  • terms of service
  • About Us
  • Careers
  • Advertising
  1. Home
  2. ProductSearch
  3. Pharmaceutical and food related
  4. Pharmaceutical intermediates and cosmetic ingredients
  5. Cosmetic materials and raw materials
  6. Cosmetic ingredients for dry and dehydrated skin, microbiome adjustment, holobiosis.

Cosmetic ingredients for dry and dehydrated skin, microbiome adjustment, holobiosis.

  • Added to bookmarks

    Bookmarks list

    Bookmark has been removed

    Bookmarks list

    You can't add any more bookmarks

    By registering as a member, you can increase the number of bookmarks you can save and organize them with labels.

    Free membership registration

last updated:Nov 06, 2025

HIGUCHI INC.
HIGUCHI INC.
  • Special site
  • Official site

An extract fermented with cold-resistant bacteria from the roots of gentian collected in the French Alps, designed for dry and dehydrated skin with microbiome-regulating ingredients.

This product is an extract fermented with rare cold-resistant bacteria that inhabit the air in France, using the roots of wild gentian organically grown in the high mountains of France. This bacteria is resistant to cold and dry environments, and the holobiosis fermented with it demonstrates effectiveness for dehydrated (water-deficient) and dry (lipid-deficient) skin, showing various efficacy data such as promoting hyaluronic acid synthesis in the epidermis and dermis, antioxidant effects, strengthening barrier functions, and promoting beneficial skin bacteria. Main components: polar lipids, amino acids, loganin acid, swertia amarin. Standardized. In Vitro: Hyaluronic acid synthesis: +62% (keratinocytes), +32% (fibroblasts) CD44 synthesis: +42% (keratinocytes) Lipid synthesis: +147% (keratinocytes) Increase in tight junction-related proteins Increase in basement membrane structural proteins (2 types) Increase in collagen-binding proteins (2 types) Increased expression of antioxidant-related genes (8 types) In Vivo: Skin surface moisture content: +7.3% (all subjects), +12.5% (seborrheic deficiency) Promotion of sebum production: +27% (all), +43% (deficiency) Wrinkle length: -5% Epidermal Staphylococcus: +39% Ralstonia species: +45%

    Cosmetic materials and raw materialsOther pharmaceutical intermediates and cosmetic ingredientsOther medical supplies and cosmetic manufacturing materials
ホロビオシス 表紙_page-0001.jpg

Cosmetic ingredients for dry and dehydrated skin, microbiome adjustment, holobiosis.

ホロビオシス 表紙_page-0001.jpg
ホロビオシス 表紙_page-0001.jpg
  • Higuchi Trading Company Product Introduction Site (Ipros)
  • Special site - Product/service details - https://pr.mono.ipros.com/higuchi-inc/product/

Inquire About This Product

  • Contact Us Online
  • Download catalog

Related Videos

basic information

Green Tech Co., Ltd. is a company established in 1992. The company has been importing and selling various types of plant extracts in Japan for about 20 years, and we have heard that Japanese customers perceive Green Tech as a manufacturer of plant extracts with a wide range of products. In fact, the company handles over 5,000 types of plant extracts. In addition to traditional plant extracts, we also produce and sell products that focus on the biodiversity of South America and the Amazon, including plant extracts and oils, as well as products developed based on microbial research that demonstrate effectiveness in maintaining microbial community homeostasis. We also manufacture and sell products derived from algae and microalgae, including components and extracted extracts. In recent years, we have been focusing on research and development, enhancing evaluation data for our products in both In-Vivo and In-Vitro studies, as well as conducting research and development in response to new trends such as skin microbiomes. Additionally, we are committed to the development and manufacturing of products that have demonstrated effectiveness by increasing the concentration of active ingredients using our proprietary freeze technology (preservation, grinding, extraction) and fermentation technology. These manufacturing technologies are not only used for the development of our own products but also support the development of customized products.

Price range

Please contact us for details

Delivery Time

Please contact us for details

Applications/Examples of results

Recommended blending amount: 1% Dry skin care products Moisturizing care products Skin holobiont active products

catalog(1)

Download All Catalogs
Cosmetic ingredients for dry and dehydrated skin, microbiome balancing ingredient, Holobiosis.

Cosmetic ingredients for dry and dehydrated skin, microbiome balancing ingredient, Holobiosis.

PRODUCT
  • E-book viewing
  • Catalog download

Contact this catalog

Company information

HIGUCHI

HIGUCHI INC.

Trading company/Wholesale

Added to bookmarks

Bookmarks list

Bookmark has been removed

Bookmarks list

You can't add any more bookmarks

By registering as a member, you can increase the number of bookmarks you can save and organize them with labels.

Free membership registration
  • Special site
  • Official site
Phone number/address

Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.

Product/Service List (171)

Related New Products

Health food and cosmetic ingredient "MICRO NMN"
Pharmaceutical and food related
Health food and cosmetic ingredient "MICRO NMN"
日本総合医療製薬
Plastic raw material "Iupital MA Series"
Materials
Plastic raw material "Iupital MA Series"
Global Polyacetal Co., Ltd.
Standardizing delivery rules for each medical institution! 'Direct Hospital Delivery Service'
Pharmaceutical and food related
Standardizing delivery rules for each medical institution! 'Direct Hospital Delivery Service'
安田倉庫

The related categories of Cosmetic materials and raw materials

  • Pharmaceutical and food related
  • Pharmaceutical intermediates and cosmetic ingredients
  • Cosmetic materials and raw materials
  • Other pharmaceutical intermediates and cosmetic ingredients
  • Medical and cosmetic materials
  • Other medical supplies and cosmetic manufacturing materials
Find products and companies by related keywords
  • #extract
  • #material
  • #Plant extracts
  • #Functional Materials
          

Inquire About This Product

  • Contact Us Online
  • Download catalog

Products

  • Search for Products

Company

  • Search for Companies

Special Features

  • Special Features

Ranking

  • Overall Products Ranking
  • Overall Company Ranking

support

  • site map
IPROS
  • privacy policy Regarding external transmission of information
  • terms of service
  • About Us
  • Careers
  • Advertising
COPYRIGHT © 2001-2026 IPROS CORPORATION ALL RIGHTS RESERVED.
Please note that the English text on this page is automatically translated and may contain inaccuracies.