A detailed explanation of technical strategies to avoid failures in the design and scale-up of bioreactors, including an Excel template with examples of design and scale-up calculations.
This book is about the design and scale-up of industrial-scale bioreactors, where information tends to be limited. It details business strategies for cost optimization and technical strategies to avoid failures in scale-up. It covers everything from the basics of bioreactors to comparisons of bioreactors used in animal cell and microbial cultures, the advantages and disadvantages of various operations, and scale-up troubles, encompassing both foundational knowledge and practical applications. Along with practical exercises using examples of design and scale-up calculations in Excel included, this book is intended for practical use. **Features of this book:** ➢ Business strategies for optimizing costs in the design of industrial-scale bioreactors ➢ Detailed descriptions of fed-batch and perfusion culture operations for high-density cultivation, which have recently gained attention ➢ Learning the reaction rates of microorganisms from the basics to design bioreactors ➢ Detailed introduction of technical strategies to avoid failures in the design and scale-up of bioreactors ➢ Comparison of animal cell culture bioreactors and microbial culture bioreactors ➢ Summary of the advantages and disadvantages of batch, continuous, and semi-batch (fed-batch) operations ➢ Excel templates for all 48 calculation problems related to bioreactors included
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【Table of Contents】 Chapter 1: Basics of Bioreactors Chapter 2: Fundamentals of Microbial Reaction Rates Chapter 3: Fundamentals of Bioreactor Operations Chapter 4: Basics and Practices of Bioreactor Design Chapter 5: Basics and Practices of Bioreactor Scale-Up Chapter 6: Troubleshooting in Bioreactor Design and Scale-Up Chapter 7: Development of Sustainable Bioreactors Appendix: How to Use Excel Goal Seek and Solver Index *When applying, please download the order form from the PDF download. *For more details, please download the PDF or contact us.
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*When applying, please download the order form from the PDF download. *For more details, please download the PDF or contact us.
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