Stable quality! For applications such as separation and analysis of plasmid DNA topoisomers.
"TSKgel HIC-ADC Butyl" is a hydrophobic chromatography column (HIC) that introduces butyl groups to a non-porous filler (5μm). It has high separation selectivity for antibody-drug conjugates (ADCs) and is effective for drug-antibody ratio (DAR) analysis. It enables high-resolution analysis of antibody drugs and biopharmaceuticals (10cm column) as well as rapid analysis (3.5cm column). Additionally, it offers high protein recovery rates and allows for trace analysis. Please feel free to contact us for inquiries. 【Features】 ■ High-resolution analysis of antibody drugs and biopharmaceuticals (10cm column) and rapid analysis (3.5cm column) is possible. ■ High separation selectivity for antibody-drug conjugates (ADCs) and effective for drug-antibody ratio (DAR) analysis. ■ Stable quality (low lot-to-lot variation, high durability). ■ High protein recovery rates and capability for trace analysis. *For more details, please refer to the PDF document or feel free to contact us.
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basic information
【Basic Characteristics】 ■Particle Size: 5μm ■Pore Size: Non-porous ■Ligand: Butyl Group ■pH Range: 2.0-12.0 ■Maximum Pressure Drop: 30MPa ■Maximum Flow Rate ・2.5 mL/min (3.5cm Column) ・1.5 mL/min (10cm Column) *For more details, please refer to the PDF document or feel free to contact us.
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【Main Target Substances and Applications】 ■ DAR analysis and purity analysis of ADCs ■ Analysis of antibody drugs, biopharmaceuticals, protein aggregates, fragment analysis, isomer separation and analysis ■ Separation and analysis of topoisomers of plasmid DNA *For more details, please refer to the PDF materials or feel free to contact us.
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The BioScience Division is engaged in business in the "Measurement Field," which includes liquid chromatography, columns, and separation agents, and the "Diagnostics Field," which focuses on immunodiagnostics, glycohemoglobin analysis, and genetic testing. In each field, we are expanding our product lineup based on distinctive technologies and establishing sales bases not only in Japan but also overseas for global business development. Additionally, the BioScience Division consistently handles everything from the development, manufacturing, and sales of equipment and reagents to maintenance and customer support, all managed by the Tosoh Group, including its affiliated companies.