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  6. [New Product] Cosmetic Ingredient: Longevity Gene Stimulator, Plant Extract for Improved Skin Lifespan

[New Product] Cosmetic Ingredient: Longevity Gene Stimulator, Plant Extract for Improved Skin Lifespan

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last updated:Jan 09, 2026

HIGUCHI INC.
HIGUCHI INC.
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Time Ris influences longevity genes, achieving improved skin lifespan [Scheduled to exhibit at the Tokyo 2025/Okinawa 2024 Cosmetics Development Expo (Booth: C11-20)]

It is an extract of the natural ruby-colored Chosen Gomi, a symbol of beauty and longevity, with a wide range of health benefits. It works on the skin longevity mechanism, leading to vibrant, radiant, and smooth skin. <Active Ingredients> Lignans: ≥10%/DM Longevity extension mechanism Schisandrin: 6-8%/DM Autophagy induction & improvement of skin health lifespan Organic Acids: Citric Acid: 10-15% Malic Acid: 10-15% Tartaric Acid ≥2% Cellular energy production <Efficacy> Unit: % Vitro SIRT6: +181 FOXO3: +104 Anti-inflammatory (NfkB: -14, IL6: -66, PGE2: -87) Antioxidant (ROS: -16, SOD2: +50, Catalase: +104) Mitochondrial activity: +55 Autophagy (LAMP2A: +80, LC3A: +44) Skin barrier (Cornifin A, Occludin: +32, Filaggrin: +160, MDA: -22, Epidermal thickness: +63) Dermis (Elastin: +16, MMP1: -72) Vivo TEWL: -24 Moisture content: +34 Microcirculation: +33 Radiance: +47

    Cosmetic materials and raw materials
タイムリス表紙_page-0001.jpg

[New Product] Cosmetic Ingredient: Longevity Gene Stimulator, Plant Extract for Improved Skin Lifespan

タイムリス表紙_page-0001.jpg
タイムリス表紙_page-0001.jpg
  • Cosmetic info Higuchi Trading Company Product List
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Green Tech Co., Ltd. is a company established in 1992. The company has been importing and selling various types of plant extracts in Japan for about 20 years, and we understand that Japanese customers perceive Green Tech as a manufacturer with a wide range of plant extracts. In fact, the company handles over 5,000 types of plant extracts. In addition to traditional plant extracts, we also produce and sell products that focus on the biodiversity of South America, particularly Brazil and the Amazon, including plant extracts and oils, as well as products developed based on microbiome research that demonstrate effectiveness in maintaining microbial community homeostasis, and components and extracted extracts derived from algae and microalgae. In recent years, we have been focusing on research and development, enhancing evaluation data for products in both In-Vivo and In-Vitro settings, as well as conducting research and development on new trends such as skin microbiome, circadian rhythms, and senescent cells. Additionally, we are committed to the development and manufacturing of products that have demonstrated effectiveness by increasing the concentration of active ingredients using our proprietary freeze technology (preservation, grinding, extraction) and fermentation technology. These manufacturing technologies support not only the development of our own products but also the development of customized products.

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Recommended mixing amount: 1% pH 4.0-8.0 Usage precautions: It is recommended to add during cold process.

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Cosmetic ingredient that stimulates longevity genes and extends skin lifespan: Skin Longevity Plant Extract Timelys.

Cosmetic ingredient that stimulates longevity genes and extends skin lifespan: Skin Longevity Plant Extract Timelys.

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HIGUCHI

HIGUCHI INC.

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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.

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