Organic synthesis and multi-condition screening are possible with a test liquid volume of 5 mL.
ReactALL, co-developed with Pfizer, is an innovative benchtop multi-reactor system equipped with both novel automatic sampling and overhead stirring functions, making it ideal for medium throughput experiments. This cutting-edge device is specially designed to meet the needs of screening and optimizing chemical reactions, including route scouting and process development and optimization. Due to its medium throughput capability, it allows testing with small amounts of raw materials and reagents. The sampling mechanism can perform up to 18 samples during testing, while the stirring mechanism can suspend solids without grinding them, anticipating actual manufacturing needs. Additionally, an integrated camera allows for monitoring and profiling of particle size and shape, effectively addressing uneven reactions. All of this is achieved using Techobis's SmartCap technology, utilizing standard vials with a reaction volume of 5 to 10 mL. Furthermore, this SmartCap technology ensures that solvent loss during a 20-hour test under heating conditions remains within 10%, providing a highly airtight structure.
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Number of reaction vessels: 5 Type of reaction vessel: 16ml vial Usage capacity: 5 to 10ml Number of temperature profiles: 5 Temperature range: -25 to 150℃ *When the ambient temperature is 21℃±2℃, and the chiller's cooling capacity at 18℃ is approximately 1180 watts. Temperature accuracy: 0.5℃ Heating/cooling rate: 0.1 to 20 ℃/min Stirring blade shape: Impeller or spiral shape Stirring speed: 0 to 1250 rpm Turbidity detection: At each reactor External cooler (chiller): Required when used at -25 to -10 ℃ With safety valve Sample pocket: 12 to 15 μl Sample preparation time: 2.5 to 4 minutes Dilution factor: 70 times Sample vial: Standard HPLC Number of sampling per reactor: 16 to 18 Inline analysis: Particle image camera or Raman probe (total of 5 units) Analysis of particle size and shape: Available - with particle image camera Data export: Word report, XML Size (D x W x H cm): 93 x 52 x 43
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Physio-Machina Co., Ltd. is a company that primarily sells products such as formulation development equipment and dissolution testers, conducts validation and calibration of peripheral devices, and engages in the import and export of software and various equipment. Additionally, it actively provides translation and interpretation of technical documents and seminars, as well as support for the creation of SOPs and conducts training sessions.