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High reliability and effective new generation virus removal filter! Based on the first generation Viruclear VF, we have optimized the membrane treatment process and launched the optimized composite PES membrane virus removal filter, Viruclear VF Plus. The strength of the optimized membrane structure is more assured, the filtration capacity for proteins has effectively improved, and adaptability to relatively complex products has also been enhanced. Viruclear VF Plus is part of the PES membrane virus removal product line promoted by Covetter, primarily aimed at the purification of biological preparations such as recombinant proteins expressed in animal cells, monoclonal antibodies, ADCs, and high purity/stability bispecific antibodies.
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[Features] - Achieves high capacity and high yield of virus retention through unique surface hydrophilicity treatment of PES membranes - Asymmetric membrane structure, high void ratio, high flux - Strong removal of parvoviruses - Removal rate of model viruses of over 4.0 log - Maintains strong retention even during process interruptions - Chemically stable - Easy installation, use, and integrity testing
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Applications/Examples of results
Representative applications: - Monoclonal antibodies - Bispecific antibodies - Fc fusion proteins - Nanobodies - Recombinant Covid vaccines - Low molecular weight recombinant proteins (less than 180kD), etc.
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Nihon Kobetta Technology Co., Ltd. is the largest comprehensive filtration solution manufacturer in Asia. We provide a diverse lineup ranging from pharmaceutical-grade cartridge and capsule filters to single-use systems and virus removal filters, all at stable and cost-effective prices. We contribute to the stable production of pharmaceutical and medical device manufacturers around the world.