Monitoring of PFAS in the atmosphere and indoor air using TD-GC-MS.

Introduction to Analytical Methods: Key points for TD-GC-MS/MS analysis conditions to accurately monitor low concentrations of PFAS in the air.

TD-GC-MS/MS is a system suitable for the analysis of volatile PFAS in the air. TD concentrates the target substances from hundreds of liters of air and connects to a high-sensitivity triple quadrupole GC-MS/MS to detect concentrations in pg/m3. Since PFAS exist in low concentrations in the air, the system requires a low detection limit. Additionally, because PFAS are widely used in various products, it is crucial to ensure there is no contamination from the system or components. Evaluating background levels is essential for obtaining reliable analytical results. The technical documentation for PFAS analysis in indoor air presents examples of screening analysis using full scan and high-sensitivity analysis using target SRM for 19 PFAS components emitted from indoor air and everyday products. It evaluates the emissions from indoor air in diverse workplace spaces and everyday items. Methods for measuring PFAS released from solid samples, such as everyday products, without pre-treatment are also introduced. The technical documentation for PFAS analysis in the atmosphere introduces high-throughput analysis of neutral and ionic PFAS. It also shares know-how for improving analytical accuracy using samples collected from three locations in an industrial park.

Analytical Equipment and Devices