Olink Explore HT

■Connecting Biomarker Discovery to Clinical Application - Explained with Real Cases of Neurodegenerative Diseases Although biomarkers are discovered, many do not reach clinical application. The reasons for this lie in multiple hurdles that arise after discovery, such as "narrowing down candidates," "reproducibility," and "connecting to clinical practice." 1. How should promising candidates obtained from comprehensive exploration be narrowed down? 2. How can reproducibility and scalability be ensured? 3. What are the key points for smoothly transitioning to clinical research? 4. What should be considered in data science throughout the overall flow? In this online seminar, we will clearly explain specific strategies for advancing from discovery to clinical application based on actual research cases of Alzheimer's disease and multiple sclerosis, in an easy-to-understand manner in Japanese. *Olink products and services are for research purposes only. Please note that they cannot be used for diagnostic purposes.

This webinar will showcase the innovative impact of Olink's proteomics platform on neuroscience research and precision medicine. It will explain the advantages of large-scale protein analysis for elucidating the complex pathomechanisms of neurodegenerative diseases, early diagnosis, biomarker discovery, and accelerating drug target identification. The discussion will delve into how understanding neuroimmune interactions, brain inflammation, and regulatory pathways through proteomics technology contributes to achieving more precise and personalized healthcare. Examples of the application of Olink technology in various neurological disease fields, such as multiple sclerosis (MS), Alzheimer's disease, amyotrophic lateral sclerosis (ALS), and Parkinson's disease, will be presented, along with contributions to the development of personalized treatment strategies and improvements in diagnostic accuracy. ▶ Title: Neuroscience Research and Precision Medicine Utilizing Olink - Insights from Key Papers ▶ Speaker: Katsuhiko Sasaki (Field Application Scientist, Life Technologies Japan)

Olink Explore HT is a next-generation proteomics analysis platform that enables the high-sensitivity and high-throughput measurement of numerous proteins from small sample volumes. In this webinar, we will explain the technical features and utilization points of Olink Explore HT and the new product Reveal, based on our analysis experience using actual BioBank Japan samples. We will also introduce the differences from other platforms such as SomaScan and Illumina Protein Prep, from the perspectives of analysis design and data characteristics. This content will provide practical insights for researchers considering options for proteomics analysis in large cohort studies and biomarker discovery. Speaker: Dr. Akinori Kanai (Associate Professor, Center for Life Data Science, Graduate School of Frontier Sciences, The University of Tokyo)