Development of new gene therapy formulations
To efficiently discover groundbreaking new drugs, there is a demand for rapid and reliable small-scale formulations, and the NanoAssemblr Spark is a device that meets this need for small-volume nanomedicine production.
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basic information
Drug Delivery and Gene Introduction ■ Nanoparticle Production ○ Lipid Nanoparticles (LNPs) ○ Gene Introduction into T Cells ○ Gene Introduction into Hematopoietic Stem Cells
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Applications/Examples of results
The development of innovative pharmaceuticals is inherently associated with the use of expensive and limited new materials. Spark can be considered the ideal device for screening formulations of new gene medicines due to the following features: ■ Intuitive operation Simply pipette the materials into the wells, press the start button, and collect the finished samples by pipetting. ■ Rapid production Formulations are completed in under 10 seconds each, allowing for hundreds of formulations within a few hours. ■ Reliable process Electric control eliminates variability between batches and users. ■ Workflow-conscious design Spark is designed with consideration for use within a clean bench. The produced nanoparticles can also be added directly to cultured cells on-site. ■ Scalability By using NxGen microfluidic technology, formulations can be easily scaled up through a series of NanoAssemblr products.
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Company information
Neppajine takes pride in contributing to the peace and progress of humanity through biotechnology as a specialized company in life science research equipment, including electroporation (gene introduction using electric pulses) and sonoporation (gene introduction using ultrasound). We believe it is our mission to provide excellent products and information not only within Japan but also to universities, research institutes, hospitals, and private companies around the world. In practice, we have numerous products in use, including gene introduction devices, cell fusion devices, and ultrasound gene introduction devices. We continuously absorb cutting-edge knowledge and technology in biotechnology, engage in close sales activities with our users, provide the latest products, technologies, and information, and respond with a rapid maintenance system. Towards the development of humanity and a bright, happy future, Neppajine will continue to move forward strongly alongside biotechnology.
![A tool that can perform everything from the production of lipid nanoparticles to screening [Materials provided].](https://image.mono.ipros.com/public/product/image/356/2000795093/IPROS53595807193677432279.png?w=280&h=280)
