A total beauty oil that awakens vitality.
- Fermented squalane extracted from Paphia yeast and extra virgin olive oil from Shodoshima. - Contains 155 types of beauty ingredients, including β-carotene and other carotenoids. - In addition to antioxidant effects against DPPH radicals, singlet oxygen, and lipid peroxides, it suppresses skin cell damage caused by reactive oxygen species. - Anti-wrinkle and firmness improvement effects through the inhibition of collagenase, hyaluronidase, and elastase. - Moisturizing and barrier function: Promotes the proliferation of epidermal keratinocytes and the gene expression of claudin-1, occludin, hyaluronic acid synthase, ceramide synthesis-related enzymes, and filaggrin. - Anti-inflammatory: Suppresses IL-8 production during inflammation. - UV protection: Suppresses skin cell damage and the breakdown of collagen and hyaluronic acid caused by UV exposure. - Whitening and transparency: Inhibits tyrosinase, suppresses the formation of carbonylated proteins, and has anti-glycation effects. In human repeated application tests, it shows improvement in stratum corneum moisture content, trans-epidermal water loss, elasticity, collagen density, and skin tone. Example of feature development: https://www.toyohakko.com/products/fermented-provitamin-oil/
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Safety test data Ames test: Negative Skin irritation test (alternative method OECD TG439): Non-irritating Eye irritation test (alternative method OECD TG492): Non-irritating Phototoxicity test (alternative method OECD TG 495): Negative Human patch test (24-hour occlusion, 20 subjects): Safe product Human skin sensitization test (RIPT, 50 subjects): No cumulative irritation or sensitization
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We support various companies' businesses through OEM manufacturing of health foods and cosmetics blended with our unique fermentation ingredients, as well as providing original ingredients. Our original fermentation/extraction ingredients have obtained numerous evidence of efficacy and safety, along with patents. We will work together to achieve product differentiation and characterization through the power of technology.
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