Filler×アジレント・テクノロジー株式会社 - メーカー・企業と製品の一覧

PLRP-S allocation usage

The batch size of the filler is up to 600L! It is possible to fill a single batch of filler into multiple columns.

We would like to introduce our LC column for bio-pharmaceutical analysis, the 'PLRP-S for preparative use'. The PLRP-S packing material, made from robust polystyrene/divinylbenzene particles, is available in various pore sizes to enable the separation of a wide range of compounds, from low molecular weight to high molecular weight, including biopolymers. With excellent chemical stability (up to 1M NaOH), it allows for cleaning and regeneration, enabling long-term use of the column. 【Features】 ■ Capable of handling scales from drug discovery to several kg of cGMP manufacturing, reducing method development time. ■ Improved selectivity and extended column lifespan through chemical stability, optimization, cleaning, and regeneration of separations. ■ Reduced system downtime and validation costs by filling multiple columns in a single batch. *For more details, please refer to the related links or feel free to contact us.

企業：アジレント・テクノロジー株式会社
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Bond Elut SCX

Bond Elut SCX is a strong cation exchange resin with a very low pKa similar to PRS.

Bond Elut SCX is a strong cation exchange resin with a very low pKa similar to PRS. However, due to the presence of benzene rings on the SCX surface, it has a higher potential for hydrophobic interactions compared to PRS. When using the packing material as an ion exchange in an aqueous solvent matrix, it is necessary to take into account the hydrophobic nature of SCX. This duality is beneficial for compounds that exhibit both cationic and hydrophobic properties. The interactions resulting from this dual nature are superior to purifications that use only a single binding phase. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut PSA

Bond Elut PSA is similar to NH2.

Bond Elut PSA is similar to NH2. The anion exchange resin PSA (1.4 meq/g) offers a slightly higher ion exchange capacity compared to NH2 (1.1 meq/g) due to its two amine groups, and the pKa of its primary and secondary amine groups is higher (10.1 and 10.9, respectively). Therefore, PSA is a slightly stronger anion exchanger than NH2. The PSA functional group has very good bidentate ligand properties, making PSA an excellent packing material for chelation. Higher carbon loading compared to NH2 packing materials promotes hydrophobicity and makes it a good choice for compounds with high polarity that are strongly retained by NH2 packing materials. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut PRS

Bond Elut PRS is a highly hydrophilic strong cation exchange that shows no notable hydrophobic interactions.

Bond Elut PRS is a highly hydrophilic strong cation exchange material, and there are no notable hydrophobic interactions observed. In non-polar solvents, it exhibits properties of hydrophilic interactions and hydrogen bonding. Due to the low pKa of PRS, cationic compounds must elute either by using a high ionic strength buffer or by suppressing the charge to isolate the cations. Therefore, PRS is effective for weak cations such as pyridine compounds. With relatively few hydrophobic secondary interactions, combined with its low capacity, PRS offers a unique set of selectivity features. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut PBA

Bond Elut PBA is a unique packing material that binds phenylboronic acid to a silica gel surface.

Bond Elut PBA is a unique packing material that binds phenylboronic acid to a silica gel surface. The strength of the covalent bond is due to interactions that are 10 to 100 times greater than other extraction mechanisms, allowing compounds to bind more firmly to the packing material surface. As a result, it can withstand strong cleaning and can be completely cleaned up. Boron bases show high selectivity for compounds with cis-diol groups, such as catechols, nucleic acids, low molecular weight proteins, and carbohydrates. PBA has been proven to be particularly effective for the separation of catecholamines from biological fluids and for the separation of RNA from DNA. It can also be applied to cis-amino alcohols like propanol. When functional groups of compounds are present on the same surface, the retention capacity becomes strong. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut Diol (2OH)

Glycol (2OH) is typically used to extract polar substances from nonpolar solvents.

Diol (2OH) is typically used to extract polar substances from non-polar solvents. The strong hydrogen bonding capability of diol is similar to that of non-bonded silica, and its ability to distinguish between similar compounds, such as structural isomers, is common with the main capabilities of silica. The separation of prostaglandins using diol can be achieved by gradually changing the polarity of the solvent during elution. Diol is a filler with higher reproducibility compared to silica in normal phase systems, allowing for predictable results. Diol can also be used to retain non-polar compounds due to hydrocarbon spacers. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut DEA

The features of Bond Elut DEA and Bond Elut NH2 are similar in several respects.

The characteristics of Bond Elut DEA and Bond Elut NH2 are similar in several respects, and they are also somewhat akin to Bond Elut PSA. DEA has a slightly lower exchange capacity (1.0 meq/g) as an anion exchange packing material compared to NH2, and the addition of a carbon chain to the functional group has further increased its hydrophobicity. Even with the presence of the main functional group, DEA also functions as a packing material with moderate polarity due to the carbon chain. While DEA is somewhat more polar than C8, it is less polar than C2 or CN. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut CN-E

Bond Elut CN-E is a medium-strength reversed-phase packing material with many applications.

Bond Elut CN-E is a medium reverse phase stationary phase with many application examples. It is ideal for applications involving extremely nonpolar compounds that are irreversibly retained by reverse phase stationary phases such as C18 and C8. End-capped cyano stationary phases are very useful when extracting compounds from aqueous matrices. *For more details, please refer to the PDF materials or feel free to contact us.*

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Bond Elut Cellulose

Bond Elut Cellulose is filled in a clean 3mL polypropylene cartridge with minimal elution.

Bond Elut Cellulose is filled in a clean 3mL polypropylene cartridge with minimal elution. The granulated cellulose powder bed is secured in place with two 20μm polyethylene frits. The unique rod shape and precisely adjusted cellulose particles maintain a free-flowing feel even when dry. For the cellulose raw material, high-purity cotton with a very high cellulose content is used to ensure optimal packing characteristics of the column. This results in the production of a high-density, highly stable, smoothly packed head column. In addition, the cellulose phase is very stable over a wide range of pH values and has an extremely low metal content (Fe and Cu content is below 5ppm). The combination of surface area and polymer structure results in a packing material with excellent retention capacity. *For more details, please refer to the PDF document or feel free to contact us.

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Bond Elut Alumina (AL-N)

Alumina is a filler that has extreme polarity, similar to silica.

Alumina, like silica, is an extremely polar filler. The surface of alumina tends to be stable at a higher pH state than non-functionalized silica. Due to its fine particle size and high extraction efficiency, a small amount of filler (50 mg) is generally used. Bond Elut AL-N has an electrically neutral surface, allowing it to retain compounds such as aromatic and aliphatic amines. It can also be used to extract either non-polar or polar compounds from hydrophilic or hydrophobic samples, respectively. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut Florisil

Florisil is a silica gel that contains magnesium oxide.

Florisil is a silica gel that contains magnesium oxide. Like silica, it has a very high polarity by nature, making it suitable for the separation of polar compounds from non-polar matrices. This filler has a large particle size, allowing for high-speed flow of large volume samples. Therefore, it becomes an effective alternative to silica when the viscosity of the sample matrix is extremely high. With Agilent's large-capacity bulk packages for SPE cartridges and plates, you can reduce costs and simplify inventory management. *For more details, please refer to the PDF materials or feel free to contact us.

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Bulk filler

Sample leak bulk adsorbent

Sample leak adsorbents can be purchased in bulk, allowing you to freely choose reservoirs and frits to customize SPE cartridges or perform "flash" chromatography. *For more details, please refer to the PDF materials or feel free to contact us.*

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Bondesil Bulk Filler

Bondesil packing material identical to that filled in Bond Elut cartridges.

The same Bondesil packing material that is filled in Bond Elut cartridges can be provided in bulk for large-scale purification or custom cartridge creation. The chemically bonded Bondesil packing material was specifically designed for separations that require selectivity, such as the following. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut CBA

Silica-based medium-polarity filler with carboxypropyl groups.

Bond Elut CBA is a silica-based medium-polarity packing material with carboxypropyl groups, which exhibits hydrophilic/hydrophobic interactions depending on the matrix and solvent environment. Its main characteristic lies in weak cation exchange. Due to its pKa value of 4.8, CBA does not require the extremely high alkaline environment that other cation exchange packing materials need for elution. At pH 4.8 and above, most of the functional groups carry a negative charge as cation exchange sites. Lowering the pH to 2.8 neutralizes CBA, allowing it to release and elute the compounds it has retained from the packing material. CBA is particularly suitable when dealing with very strong cationic compounds. Additionally, CBA broadens the selectivity range for counterions compared to other cation exchangers, increasing the options for elution buffers. *For more details, please refer to the PDF document or feel free to contact us.*

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Bond Elut SI

Bond Elut Silica is a polar packing material.

Bond Elut Silica is a polar packing material. Non-bonded active silica exhibits acidity. SI is a packing material used for the highly selective separation of compounds with similar structures. To elute target compounds present in a non-polar solvent, you can increase the polarity of the solvent by adding a polar solvent such as THF or ethyl acetate, allowing for recovery. *For more details, please refer to the PDF document or feel free to contact us.

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Filler×アジレント・テクノロジー株式会社 - メーカー・企業と製品の一覧

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