Column for high-performance liquid chromatography (HPLC) for oligonucleotide purification using polymer beads.
The OligoSep HC Cartridge manufactured by ADS Biotec (formerly Transgenomic) is a column that uses porous beads made of alkylated polystyrene-divinylbenzene.
Due to the porous nature of the beads, the surface area of the column beads is larger compared to non-porous beads, allowing for the purification of a greater volume of samples.
It can be used not only for the purification of oligonucleotides but also for the analysis of single-stranded and double-stranded DNA.
It is compatible with various types of high-performance liquid chromatography (HPLC) systems.
By using buffers manufactured by ADS Biotec as the mobile phase, high-precision separations can be achieved.
Additionally, by following the procedures outlined in the instruction manual and washing the column with 75% acetonitrile, the column can be reused multiple times.