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HPLC Columns Product List and Ranking from 14 Manufacturers, Suppliers and Companies | IPROS GMS

Last Updated： Aggregation Period:Apr 08, 2026～May 05, 2026
This ranking is based on the number of page views on our site.

HPLC Columns Manufacturer, Suppliers and Company Rankings

Last Updated： Aggregation Period:Apr 08, 2026～May 05, 2026
This ranking is based on the number of page views on our site.

  1. 東ソー バイオサイエンス事業部　計測分野 Tokyo//Chemical
  2. メルク株式会社ライフサイエンス（シグマ アルドリッチ ジャパン合同会社） Tokyo//Testing, Analysis and Measurement
  3. サーモフィッシャーサイエンティフィック株式会社／Thermo Fisher Scientific K.K. Tokyo//Testing, Analysis and Measurement
  4. 日本ウォーターズ（米国本社 Waters Corporation）　 Tokyo//Testing, Analysis and Measurement
  5. 5 ADSTEC Corporation Bio Department Chiba//others
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HPLC Columns Product ranking

Last Updated： Aggregation Period:Apr 08, 2026～May 05, 2026
This ranking is based on the number of page views on our site.

  1. High-performance columns for HPLC, UHPLC, and UPLC [CORTECS] 日本ウォーターズ（米国本社 Waters Corporation）　
  2. [Data] RP-Amide HPLC/UHPLC Column メルク株式会社ライフサイエンス（シグマ アルドリッチ ジャパン合同会社）
  3. DNAPac PA200/PA200 RS Column サーモフィッシャーサイエンティフィック株式会社／Thermo Fisher Scientific K.K.
  4. 4 HPLC Column "Reversed Phase / HILIC" 東ソー バイオサイエンス事業部　計測分野
  5. 4 Shim-pack Series Catalog

HPLC Columns Product List

31～60 item / All 77 items

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HPLC column for oligonucleotide HPLC purification - OligoSep Prep HC Cartridge

HPLC column for oligonucleotide HPLC purification - OligoSep Prep HC Cartridge

High-performance liquid chromatography (HPLC) column for the purification of synthetic oligonucleotides.

The OligoSep Prep HC Cartridge manufactured by ADS Biotec (formerly Transgenomic) is a column for the purification of oligonucleotides using ion-pair reverse phase HPLC. It uses porous beads made of alkylated polystyrene-divinylbenzene (PS-DVB). Due to the porous nature of the beads, the surface area is increased, allowing for the purification of larger amounts of samples. It can be used for the purification of synthetic oligos. It is compatible with various types of high-performance liquid chromatography (HPLC) systems. By using ADS Biotec's buffer as the mobile phase, high-precision separation can be achieved. Additionally, by following the procedures outlined in the instruction manual and washing the column with 75% acetonitrile, the column can be reused multiple times.

  • High Performance Liquid Chromatograph
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Application Note: HPLC Products for Oligonucleotide Analysis

Application Note: HPLC Products for Oligonucleotide Analysis

HPLC column and buffer for oligonucleotide analysis

The HPLC columns and buffers for oligonucleotide analysis manufactured by ADS Biotec in the United States use beads made of alkylated polystyrene-divinylbenzene. The columns are referred to as the OligoSep series. Oligonucleotides are used in research for antisense and siRNA pharmaceuticals.

  • High Performance Liquid Chromatograph
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mRNA analysis HPLC products RNASep series

mRNA analysis HPLC products RNASep series

Capable of handling everything from mRNA analysis to purification! RNASep series

The RNASep series from ADS Biotec in the United States is capable of handling everything from mRNA analysis to purification.

  • High Performance Liquid Chromatograph
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HPLC column for optical isomer separation

HPLC column for optical isomer separation

HPLC column for optical isomer separation

Optical isomers present in various bioactive substances (such as pharmaceuticals, pesticides, and fragrances) that are deeply related to our daily lives are known to exhibit significantly different biological activities between isomers, increasing the necessity for the analysis and separation of optical isomers. The "SUMICHIRAL OA series" HPLC columns for the separation of optical isomers are gaining attention in fields such as pharmaceuticals and pesticides.

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F5 (PFP) HPLC/UHPLC column

F5 (PFP) HPLC/UHPLC column

Separation of positional isomers using reverse phase and HILIC analysis! An additional step to add to C18 and HILIC columns.

The "F5 (PFP) HPLC/UHPLC column" for metabolomics is a reversed-phase column with selectivity different from C18. By incorporating it as a second or third choice column in reversed-phase systems, the range of substances for LC analysis is broadened. Four retention mechanisms—hydrogen bonding, dipole-dipole interactions, π-π interactions, and hydrophobic interactions—complexly influence each other to exhibit unique retention characteristics and stereoselectivity. 【Features】 ■ Retains highly polar basic compounds without ion-pair reagents ■ 100% water mobile phase is usable ■ Suitable for LC/MS due to retention at high organic solvent concentrations ■ Supports both analysis and fractionation *For more details, please refer to the PDF document or feel free to contact us.

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Ascentis Express HILIC Guide

Ascentis Express HILIC Guide

Retention and separation of hydrophilic compounds made faster! Choose the right column for your needs with the HILIC stationary phase selection guide.

This document provides an explanation of HILIC and features various types of HILIC stationary phase columns. HILIC technology, which has complementary properties to both reverse phase (RP) and normal phase (NP) chromatography, is often used in studies analyzing hydrophilic analytes. Additionally, we offer a lineup of products including the "Ascentis Express OH5 HPLC column," "Ascentis Express ES-Cyano HPLC column," and others. We invite you to read through it. [Contents (excerpt)] ■ Ascentis Express U/HPLC columns ■ What is HILIC and reasons to choose it ■ Development of HILIC methods ■ Ascentis Express OH5 HPLC column *For more details, please refer to the PDF document or feel free to contact us.

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[Data] RP-Amide HPLC/UHPLC Column

[Data] RP-Amide HPLC/UHPLC Column

Improvement of retention for carboxylic acids and phenolic compounds! Achieving low bleed suitable for LC-MS applications.

This document provides an explanation of "RP-Amide HPLC/UHPLC columns." It introduces the "characteristics of RP-Amide," the "differences in retention for neutral analytes," and the "increased retention for hydrogen bond donors." Additionally, it includes analyses of "ulcer medications using Ascentis RP-Amide" and "UHPLC measurements of sunscreen drugs using Ascentis Express RP-Amide, 2.7μm." We encourage you to read it. 【Contents】 ■Ascentis RP-Amide HPLC column ■Analysis of ulcer medications using Ascentis RP-Amide ■UHPLC measurements of sunscreen drugs using Ascentis Express RP-Amide, 2.7μm ■Data sheet on the care and use of Ascentis Express RP-Amide columns ■LC/MS workflow products ■Ascentis RP-Amide product list ■Fused-Core product list *For more details, please refer to the PDF document or feel free to contact us.

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Acclaim Surfactant Plus Column

Acclaim Surfactant Plus Column

For the analysis of consumables such as detergents, pharmaceuticals, food and beverages, and environmental samples! HPLC column.

The "Acclaim Surfactant Plus Column" is a state-of-the-art HPLC column with high efficiency and silica-based material. It allows for the simultaneous analysis of cationic surfactants, anionic surfactants, nonionic surfactants, and amphoteric surfactants. It can be used for the analysis of consumables such as detergents, pharmaceuticals, food and beverages, and environmental samples. 【Features】 ■ Selectivity suitable for the simultaneous analysis of cationic surfactants, anionic surfactants, nonionic surfactants, and amphoteric surfactants ■ Measurement of cationic surfactants ■ Separation of ethoxylated surfactants ■ Retention of highly hydrophilic compounds such as hydrotropes *Please feel free to contact us for more details.

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HPLC column "Acclaim Trinity P2 column"

HPLC column "Acclaim Trinity P2 column"

An ideal solution for counterion analysis in pharmaceuticals.

The "Acclaim Trinity P2 Column" is a high-performance silica-based column. It is particularly suitable for HPLC analysis of counter ions in charged pharmaceuticals. The usage is simple, it boasts excellent robustness, and it allows for the analysis of both monovalent and multivalent ions using fast general-purpose methods. Using a general-purpose HPLC, it is possible to effectively analyze counter ions with just one column and one type of analytical method. 【Features】 ■ Effectively analyzes ions using HPLC ■ Enables screening of counter ions present in pharmaceuticals ■ Retains ions or ionic compounds without using ion-pair reagents ■ Simple to use ■ Provides reproducible packing *For more details, please refer to the PDF materials or feel free to contact us.

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DNAPac PA200/PA200 RS Column

DNAPac PA200/PA200 RS Column

High separation of oligonucleotide chains and stereoisomers! Anion exchange column.

The "DNAPac PA200 HPLC/DNAPac PA200 RS (High-Speed Separation) UHPLC Column" is a column designed for the high separation of ssDNA and RNA. The selectivity for oligonucleotides can be controlled by various parameters such as the pH of the mobile phase, solvents, and the use of different salts, allowing for adjustments in separation to meet the specific requirements of applications. We provide structural analysis and quantification methods utilizing high-resolution mass spectrometry and anion exchange columns for UHPLC. 【Features】 ■ High separation of oligonucleotide chains and stereoisomers ■ Improved separation and throughput ■ Control of selectivity and retention through the pH of the mobile phase, type of salt, and type of mobile phase ■ Separation of n from n-1 bases *For more details, please refer to the PDF document or feel free to contact us.

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Basics of Ion Chromatography: Anion Exchange Column

Basics of Ion Chromatography: Anion Exchange Column

A clear explanation of the basics of ion chromatography! Let's understand the anion column, which is important in analysis.

If optimization of separation cannot be achieved by adjusting the elution solution or temperature, it is recommended to change the type of column. Using columns with different performance can significantly alter the separation depending on the ionic components. We will explain our anion columns.

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Basics of Ion Chromatography: Cation Exchange Column

Basics of Ion Chromatography: Cation Exchange Column

A clear explanation of the basics of ion chromatography! Let's understand the important cation columns in analysis.

If optimization of separation cannot be achieved by adjusting the elution liquid or temperature, it is recommended to change the type of column. Using columns with different performance can significantly alter the separation depending on the ionic components. We will explain our cation columns.

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Acclaim Mixed-Mode HPLC Column

Acclaim Mixed-Mode HPLC Column

A column that is expected to provide high separation.

Liquid chromatography aims to achieve good separation ability to obtain meaningful information through peak resolution. In mixed-mode chromatography, numerous parameters can be adjusted to optimize separation efficiency, allowing for effective control of separation performance. The Thermo Scientific Acclaim mixed-mode column features unique surface chemistry that facilitates easy adjustment of analyte elution, enabling maximum separation efficiency, which often leads to successful separation of compounds that cannot be addressed by other conventional high-performance liquid chromatography (HPLC) columns. The combination of ion exchange and reversed-phase, specifically HILIC chemistry, can extract the chemical properties of sample mixtures, allowing for complete separation of components in complex samples or high-sensitivity detection of trace samples. However, it is impossible to retain highly polar or charged analytes using only reversed-phase chromatography. Ion exchange (IEX) chromatography alone is insufficient for separating hydrophobic compounds. By using columns that combine different functionalities, a completely new toolkit is obtained for separating and evaluating samples.

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Fully porous HPLC column

Fully porous HPLC column

You can easily change the method from a fully porous particle column to a surface porous particle column!

The product features various advantages of fully porous particle columns, such as high retention, load capacity, and solvent resistance. It can be expanded to suit your method, from UHPLC to preparative LC. Additionally, the InfinityLab Poroshell bonded phase is compatible with the traditional ZORBAX bonded phase, allowing for easy method changes from fully porous particle columns to superficially porous particle columns. 【How to choose the appropriate particle for your method (partial)】 ■1.8μm ZORBAX RRHD: Achieves the highest level of performance with UHPLC equipment - Maximum pressure: 1200 bar - Compatible systems: 1290 Infinity II LC or 1260 Infinity II Prime LC ■1.8 ZORBAX RRHT: Ultra-fast chromatography with a maximum of 600 bar - Maximum pressure: 600 bar - Compatible systems: 1260 Infinity II LC *For more details, please refer to the PDF document or feel free to contact us.

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ZORBAX Rx Reverse Phase HPLC Column

ZORBAX Rx Reverse Phase HPLC Column

Rx-C18 is recommended for separation in low pH regions! It shows excellent stability and peak shape.

The "ZORBAX Rx Reverse Phase HPLC Column" is suitable for high-throughput analysis. It shows different selectivity compared to Eclipse XDB-C18 and StableBond SB-C18 in the low pH range, and StableBond is recommended for high-temperature applications. Additionally, Rx-C18 is manufactured using dimethyl octadecyl silane and demonstrates excellent stability up to pH 9 due to the lack of end-capping. 【Features】 ■ Shows different selectivity compared to Eclipse XDB-C18 and StableBond SB-C18 in the low pH range ■ Exhibits excellent stability and peak shape in low pH applications ■ Rx-C18 is manufactured using dimethyl octadecyl silane and demonstrates excellent stability up to pH 9 due to the lack of end-capping ■ Rx-C8 is the same product as SB-C8 *For more details, please refer to the PDF document or feel free to contact us.

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ZORBAX Extend-C18

ZORBAX Extend-C18

Improvement of retention, separation ability, and peak shape in base compounds! Introducing ZORBAX reverse phase HPLC columns.

The "ZORBAX Extend-C18" utilizes a groundbreaking bidentate C18-C18 bonding technology, enabling the development of high-separation methods in high pH regions while being a silica-based column. The unique bidentate bonding and double-end capping enhance stability at high pH. It improves retention, separation capability, and peak shape for basic compounds. To extend column life, it is preferable to use triethylamine, ammonium hydroxide, or pyrrolidine as buffer solutions, while phosphate buffers are not recommended. 【Features】 - High separation efficiency and long lifespan in high pH regions (up to pH 11.5) - Improved stability at high pH due to unique bidentate bonding and double-end capping - Higher efficiency and superior peak shape compared to polymer-based columns - High sensitivity and separation for LC/MS analysis of peptides and proteins *For more details, please refer to the PDF document or feel free to contact us.

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HPLC column "Sunniest"

HPLC column "Sunniest"

Developing a new combined phase! A column with an unprecedented end capping.

"Sunniest C18" uses a tri-functional reagent and features end-capping based on a unique new concept, making it the only one in the world. "Sunniest" significantly suppresses the influence of residual silanol groups, allowing for a wider range of conditions without tailing of basic compounds, and enabling the optimal setting of mobile phase pH and column temperature. 【Features】 ○ Almost no influence from silanol groups ○ Superior end-capping ○ The bonding reagent also has the effect of end-capping ○ RP-AQUA is prepared for stable separation with 100% aqueous mobile phase ○ Columns are available from an inner diameter of 2.0mm to 20mm for preparative use For more details, please contact us or download the catalog.

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Core shell type column "SunShell C4-100"

Core shell type column "SunShell C4-100"

Reverse phase column for the separation of monoclonal antibodies with a pore diameter of 1000A! Utilizing core-shell particles to achieve high theoretical plate numbers!

The "SunShell C4-100" is a core-shell type column for the separation of monoclonal antibodies. SunShell columns utilize core-shell silica and a specially modified Sunniest-bonding method, achieving efficient deactivation of silanol groups while also possessing high durability. Additionally, by using core-shell particles, the theoretical plate number per pressure increases, allowing for high separation to be easily achieved even with existing HPLCs that do not have high pressure tolerance. 【Features】 ■ Uses core-shell particles to achieve a high theoretical plate number ■ Usable in both HPLC and UHPLC with low pressure and high theoretical plate number ■ Sharp peak shapes due to excellent end-capping *For more details, please download the PDF or feel free to contact us.

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"Cogent TYPE-C Silica" HPLC column

"Cogent TYPE-C Silica" HPLC column

Unique "TYPE-C Silica" used in columns for Cogent HPLC manufactured by MicroSolv in the USA.

The "Cogent TYPE-C column," developed by MicroSolv in the United States, is a next-generation HPLC column based on high-purity Type-B silica that has been modified to replace over 95% of the silanol (Si-OH) on the silica surface with silane (Si-H). By replacing over 95% of the silanol with Si-H, a strong hydrophobic surface is created, providing greater stability compared to traditional silica-based phases. This means that end-capping is not necessary. 【Features】 ■ Usable in three modes in HPLC (RP (reverse phase), NP (normal phase), ANP (aqueous normal phase)) ■ High efficiency and high stability ■ Fast equilibration in gradient ■ Simultaneous separation of polar and non-polar compounds ■ Weak hydration shell *For more details, please refer to the catalog.

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ACE UltraCore UHPLC·HPLC Column

ACE UltraCore UHPLC·HPLC Column

Solid core (core-shell) particles appear in the ACE column! Unique EBT technology achieves high stability across a wide pH range.

A new UltraCore column (HPLC/UHPLC column) has been added, featuring solid core (surface porous) particles from the UK ACE column group. Compared to conventional fully porous silica, it can be used at lower pressures, and due to the limited diffusion of analytes, it achieves high efficiency and sharp peak shapes. Additionally, it employs a unique encapsulation bonding technology (EBT) that delivers stable high performance across a wide pH range, dramatically increasing the ligand coverage on the silica surface and effectively eliminating the negative effects of unbound silanols. **Features** - Utilizes ultra-inert solid core particles (surface porous) - Monodisperse particle distribution combining low pressure and high efficiency - Expanded pH stability (1.5 to 11.0) - Compatible with LC/MS buffers - Employs unique encapsulation bonding technology (EBT)

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Various columns for gas chromatography (GC) made by MEGA Corporation (Italy)

Various columns for gas chromatography (GC) made by MEGA Corporation (Italy)

We will provide valuable products at prices that satisfy our customers. Please feel free to consult us regarding your requests for the inner diameter, length, film thickness, etc., of the columns, as well as for demo columns.

MEGA Corporation has been manufacturing and selling GC columns developed in collaboration with Dr. Kurt Grob, a global authority on Fused Silica GC Capillary Columns, since 1980. Based on this technological expertise, we have acquired the "manufacturing and sales rights for Grace Corporation GC columns" and are further expanding our product range. While it is natural that our performance and lineup meet the diverse needs of our customers, another notable feature is our "pricing." ■ Unique Services Offered by MEGA 1. We actively respond to inquiries about "MEGA Customized Columns" that meet customer requests for inner diameter, length, film thickness, etc. 2. To ensure that you can start measuring immediately after purchase, we also perform "aging" as a pre-treatment before shipping, so please specify "aging" at the time of purchase. 3. We accept requests for "demo columns" for evaluation purposes. *For more details, please contact us or download the PDF materials.

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ACE C18-AR HPLC Column

ACE C18-AR HPLC Column

Mixed-mode HPLC column integrating C18 and phenyl groups.

This is an HPLC column manufactured by ACT in the UK, featuring a unique selectivity that integrates a phenyl group into a conventional C18 stationary phase. While it is a C18 phase, it exhibits selectivity for aromatic compounds like phenyl groups, providing complementary selectivity when sufficient separation cannot be achieved with C18 alone. **Features:** - A C18-phenyl integrated column that combines the advantages of both C18 phase and phenyl groups. - Utilizes ultra-high purity inert silica, demonstrating excellent peak shape and reproducibility. - Can be used with a water-rich mobile phase that enables retention and separation of polar substances. - Exhibits ultra-low bleed characteristics required for UV/LC-MS. - High-throughput column size.

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ACE C18-PFP HPLC column

ACE C18-PFP HPLC column

HPLC column with pentafluorophenyl (PFP) group bonded to C18 phase.

This is an HPLC column developed by ACT in the UK, combining C18 with a PFP group. By integrating the PFP phase, which provides complementary selectivity to conventional C18, it improves the separation of polar basic substances and demonstrates selective characteristics for halogenated aromatic compounds and positional isomers. Additionally, the C18-PFP phase possesses multiple separation mechanisms (hydrophobic, π-π, hydrogen bonding, shape selectivity), showcasing its capabilities for mixtures that are difficult or impossible to separate with conventional C18. **Features** - A mixed column that combines C18 and PFP (PentaFluoroPhenyl) phases - Enhanced separation capability for polar basic substances - "Ultra-inert & Ultra-pure silica" essential for peak shape and reproducibility - Excellent stability for temperature programming analysis - Optimal for UV and LC/MS due to ultra-low bleed characteristics

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Roc C8 HPLC column (USP L7)

Roc C8 HPLC column (USP L7)

Solid high reliability – provides the peak shape, reproducibility, robustness, and separation performance desired by users.

The Roc C8 HPLC column (USP L7) is designed to become a "standard" in LC analysis laboratories. These robust and highly reliable columns are compatible with HPLC systems that can withstand pressures up to 40 MPa, providing users with the desired peak shape, reproducibility, robustness, and separation performance for all LC applications. Their exceptional utility maximizes operational efficiency. The minimal package design allows for compact storage. 【Features】 ■ Designed to be a "standard" in LC analysis laboratories, this standard HPLC column is compatible with HPLC systems that can withstand pressures up to 40 MPa. ■ Solid high reliability – provides users with the desired peak shape, reproducibility, robustness, and separation performance. ■ Exceptional utility capable of handling a large volume of analytical tasks – diverse packing materials using high-purity silica backed by high-quality manufacturing processes are suitable for most HPLC methods. *This catalog is in English. *For more details, please download the PDF or contact us.

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Inert LC Columns

Inert LC Columns

Improve peak shape without using additives! Achieve high precision and throughput.

We would like to introduce our "Inert LC Column." We offer two products: Raptor Inert Biphenyl HPLC Columns and Raptor Inert ARC-18 HPLC Columns. There is no need for time-consuming conditioning or complex passivation. Additionally, the response and recovery rates of analytes are improved, lowering the detection limits. 【Four Benefits】 ■ Improved peak shape without using passivation or additives in the mobile phase ■ Enhanced response and recovery rates of analytes, resulting in lower detection limits ■ Minimization of variability in analytical results, achieving high precision and throughput ■ Elimination of the need for time-consuming conditioning and complex passivation *For more details, please refer to the PDF document or feel free to contact us.

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Analysis of peptides, proteins, and monoclonal antibodies by UHPLC.

Analysis of peptides, proteins, and monoclonal antibodies by UHPLC.

A technical report featuring data primarily aimed at the analysis of biopharmaceuticals.

The document includes applications using "FlexFire WP C4," as well as the upcoming FlexFire WP C18 and WP C8. It primarily features data aimed at biopharmaceutical analysis, focusing on what can be achieved with wide-pore columns. Additionally, it includes data from other WP series. Please make use of it. [Contents] ■ Retention and separation due to differences in pore size ■ Analysis of peptides ■ Analysis of cyclic peptides ■ Analysis of proteins ■ Analysis of monoclonal antibodies *For more details, please refer to the PDF document or feel free to contact us.

  • Other protein analysis
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HPLC/UHPLC column "FlexFire WP C4"

HPLC/UHPLC column "FlexFire WP C4"

For the analysis of macromolecules such as proteins and antibodies! It greatly contributes to the analysis of biopharmaceuticals.

The "FlexFire WP C4" is a column designed to target macromolecules such as proteins and antibodies. To accommodate various analytical conditions, its pH and temperature durability have been significantly upgraded compared to previous models, greatly contributing to the analysis of biopharmaceuticals in the future. Additionally, it can also be applied to the analysis of intact mAbs, in addition to proteins. 【Features】 ■Elutes proteins with various properties based on hydrophobic differences, primarily aimed at analyzing primary structural characteristics. ■Applicable for the analysis of intact mAbs. ■Ensures durability at 80°C, allowing for sharp peak elution. *For more details, please refer to the PDF document or feel free to contact us.

  • Other protein analysis
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