メルク株式会社ライフサイエンス（シグマ アルドリッチ ジャパン合同会社） List of Products and Services

As an efficient compound screening method, DNA-encoded libraries (DEL) have been established as a common technique in drug discovery settings. At Sigma-Aldrich, we have simplified DEL into an easy-to-use kit with the cooperation of DyNAbind, a company with unique dynamic library technology, to ensure that many researchers can widely utilize DEL technology. After progressing with screening according to the prepared experimental protocol, it is possible to obtain structural information of high-binding fragment compounds as a result through NGS analysis. <Sigma-Aldrich DEL Kit Features> ■ Affordable and easy access to the noteworthy DEL technology ■ A large compound library covering a wide chemical space ■ Provides more reliable results than conventional DELs due to unique dynamic library technology ■ Available for purchase as a catalog item without the need for licensing agreements *For more details, please refer to the PDF document or feel free to contact us.

The identification of metabolite biomarkers and understanding their biological roles are essential for revealing new disease diagnostic methods and therapeutic targets. Mass spectrometry, an effective technique for this purpose, continues to increase in utility. Ensuring reproducibility of results in metabolic research is very important. IROA Technologies' "Metabolite Library" provides retention times and spectra of key metabolites as standards in mass spectrometry. It supports the optimization of mass spectrometry protocols to achieve high reproducibility. 【Features】 ■ 96-well plates that are ready-to-use with over 95% purity ■ Comprehensive coverage of primary metabolites and intermediates, covering major metabolic pathways ■ Plates dispensed by solubility (water-soluble/lipid-soluble) ■ The plate map includes compound names, compound IDs, molecular formulas, molecular weights, CAS, ChEBI, HMDB ID, PubChem ID, and Substance ID *For more details, please refer to the PDF document or feel free to contact us.