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  1. Home
  2. Testing, Analysis and Measurement
  3. メルク株式会社ライフサイエンス(シグマ アルドリッチ ジャパン合同会社)
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Testing, Analysis and Measurement
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メルク株式会社ライフサイエンス(シグマ アルドリッチ ジャパン合同会社)

number of employees700
addressTokyo/Minato-ku/1-3-1 Azabudai, Azabudai Hills, Mori JP Tower, 26th Floor
phone03-4316-8000
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last updated:Dec 16, 2024
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メルク株式会社ライフサイエンス(シグマ アルドリッチ ジャパン合同会社) Product Lineup

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Ultra-pure water and pure water equipment (for testing and research) Ultra-pure water and pure water equipment (for testing and research)
Application-specific ultrapure water and pure water systems Application-specific ultrapure water and pure water systems
Pure water system for equipment supply Pure water system for equipment supply
Microbial testing of food and beverages Microbial testing of food and beverages
Standard material Standard material
Analytical reagents, consumables, and equipment Analytical reagents, consumables, and equipment
Products for protein research and analysis Products for protein research and analysis
Cell culture and analysis products Cell culture and analysis products
DDS (Drug Delivery System) DDS (Drug Delivery System)
Filtration / Filter Filtration / Filter
Screening library products Screening library products
Materials and reagents for scientific research Materials and reagents for scientific research
Reagents and equipment for organic synthesis Reagents and equipment for organic synthesis
Synthesis analysis software Synthesis analysis software
General-purpose reagents and other reagent kits/compounds General-purpose reagents and other reagent kits/compounds
Screening

Screening library products

To accelerate the discovery of lead compounds and, consequently, drug development, rapid and efficient screening technologies are essential. Merck offers tools such as the "DNA-encoded library (DEL)," which attaches short unique DNA fragments to large numbers of small molecules, allowing for the simultaneous investigation of desired activities or functions across more molecules.

DNA-encoded library (DEL): A new method for drug screening

Accelerating the early stages of research! A kit for DNA-encoded libraries (DEL) that enables compound screening using NGS.

As an efficient compound screening method, DNA-encoded libraries (DEL) have been established as a common technique in drug discovery settings. At Sigma-Aldrich, we have simplified DEL into an easy-to-use kit with the cooperation of DyNAbind, a company with unique dynamic library technology, to ensure that many researchers can widely utilize DEL technology. After progressing with screening according to the prepared experimental protocol, it is possible to obtain structural information of high-binding fragment compounds as a result through NGS analysis. <Sigma-Aldrich DEL Kit Features> ■ Affordable and easy access to the noteworthy DEL technology ■ A large compound library covering a wide chemical space ■ Provides more reliable results than conventional DELs due to unique dynamic library technology ■ Available for purchase as a catalog item without the need for licensing agreements *For more details, please refer to the PDF document or feel free to contact us.

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IROA Technologies Metabolite Library

MLSDiscovery software tool included! High quality and reasonably priced library.

The identification of metabolite biomarkers and understanding their biological roles are essential for revealing new disease diagnostic methods and therapeutic targets. Mass spectrometry, an effective technique for this purpose, continues to increase in utility. Ensuring reproducibility of results in metabolic research is very important. IROA Technologies' "Metabolite Library" provides retention times and spectra of key metabolites as standards in mass spectrometry. It supports the optimization of mass spectrometry protocols to achieve high reproducibility. 【Features】 ■ 96-well plates that are ready-to-use with over 95% purity ■ Comprehensive coverage of primary metabolites and intermediates, covering major metabolic pathways ■ Plates dispensed by solubility (water-soluble/lipid-soluble) ■ The plate map includes compound names, compound IDs, molecular formulas, molecular weights, CAS, ChEBI, HMDB ID, PubChem ID, and Substance ID *For more details, please refer to the PDF document or feel free to contact us.

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