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A free booklet summarizing case studies of online analytical devices with over 5,000 units installed worldwide! ◆ Featured Case Studies ◆ Case 1: Analysis of hydrogen sulfide and ammonia in sour water Case 2: Analysis of free cyanide, total cyanide, and WAD cyanide in gold leaching slurry and waste liquid (wet refining method) Case 3: Measurement of the concentration of "rich" amine and "lean" amine and the amount of recovered CO2 (CO2 loading) (carbon recovery plant, power generation industry) Case 4: Analysis of alkali, carbonate, hydroxide, and sulfide in pulping liquor (neutralization titration) Case 5: Analysis of calcium and magnesium in brine Case 6: Analysis of zinc, sulfuric acid, and iron Case 7: Analysis of hydrogen peroxide (HPPO method for propylene oxide production) Case 8: Analysis of sulfuric acid in acetone and phenol (cumene method) Case 9: Analysis of sulfuric acid and zinc sulfate (viscose/ rayon production) Case 10: Measurement of permanganate absorption number (PAN) (caprolactam production)

The Metronome Process Online Analyzer 2035 is a wet analysis device for various processes including petrochemicals, minerals, semiconductors, paper/pulp, wastewater/drainage, and more. It enables online analysis of titration, moisture measurement, ions, and absorbance. It is ideal for managing wastewater and monitoring manufacturing processes.

In semiconductor manufacturing, standard cleaning processes are conducted in wet benches within clean rooms, where the environment is controlled to prevent further contamination. However, it is common for space to be very limited for installing analytical instruments in such environments. To monitor the main parameters of cleaning solutions simultaneously, more safely, efficiently, and quickly without using reagents, inline analysis using near-infrared spectroscopy (NIRS) is effective. Online analyzers, process analyzers, inline analyzers.

In municipal sewage and industrial wastewater treatment plants, a large number of parameters must be continuously monitored. This includes, for example, heavy metals such as cadmium, lead, zinc, and cobalt, as well as anions like nitrates, ammonium salts, phosphates, and sulfates. Metrohm Process Analytics offers a variety of analyzers to address these applications. Metrohm's process analyzers can be easily configured to accommodate a wide range of substances and parameters, enabling reliable online monitoring.

A process Raman spectrometer that can be used for monitoring culture medium components (including glucose) and metabolic products (such as lactic acid) in cell culture.

The World Health Organization (WHO) has issued guidelines on permissible limits for about 200 substances, including nitrogen compounds such as ammonia (NH3), nitrate (NO3-), and nitrite (NO2-), based on their health risks. Therefore, wastewater treatment and compliance with regulatory values set by laws are important themes and are crucial for protecting the environment from pollutants in wastewater. These nitrogen compounds are simultaneously analyzed using a colorimetric method with low waiting times in the multi-parameter process analyzer from Metrohm Process Analytics.

Chemical Mechanical Polishing (CMP) is one of the main technologies used to smooth and polish the surface of silicon wafers. Typically, this process involves mixing deionized water, CMP slurry (colloidal silicon or alumina liquid dispersions), and hydrogen peroxide (a strong oxidizing agent) in specific concentrations and ratios. Since hydrogen peroxide degrades over time, it is necessary to continuously monitor its concentration online to efficiently repeat the CMP process. By ensuring that the CMP slurry is always within specifications and adjusting the mixture as needed, the yield of the product can be controlled.

Tetra-methylammonium hydroxide (TMAH) is a quaternary ammonium salt primarily used in the manufacturing of integrated circuits (ICs), printed circuit boards (PCBs), and flat panel displays (LCDs), and it is most commonly used in the photolithography process during the production of these devices. In this process, a photoresist developer is used to transfer patterns onto a substrate. The chemicals used in the semiconductor industry must be extremely pure because even trace amounts of contaminants can adversely affect electrical properties. The development process is a critical stage in photolithography, and it must be optimized to increase production efficiency. This process application note introduces a method for monitoring the concentration of TMAH in the developer solution through online process titration.

Pure nickel is a silvery-white metal that is very hard, corrosion-resistant, and ductile. Due to these remarkable properties, nickel is used in many applications, primarily in coatings and surface engineering. Electroless nickel plating is a self-catalyzing chemical technique for depositing a layer of nickel-phosphorus alloy onto the surface of a workpiece. This method relies on the concentration of a reducing agent (sodium hypophosphite) that reacts with metal ions for plating. However, since the lifespan of the chemicals in the plating bath is limited, automatically monitoring the consumption of these chemicals becomes an important process control requirement. Prolonged use of the plating bath leads to an overload of reaction products in the electrolyte, adversely affecting the properties of the workpiece's surface and the layer. This process application note proposes a method for regularly monitoring various active bath components in the electroless nickel plating bath to ensure the uniform deposition of nickel-phosphorus alloy layers. Online analyzers, process analyzers, inline analyzers.

The method for refining alumina from bauxite is called the "Bayer process." Since it is more cost-effective and energy-efficient to refine aluminum directly from alumina, this method involves dissolving crushed bauxite in high-temperature calcium oxide (hereafter referred to as CaO) and sodium hydroxide (hereafter referred to as NaOH) to create an "aluminate solution." Additionally, CaO is causticized and removed by the carbonate generated from the decomposition of organic matter in the alkaline solution and the absorption of CO2 from the atmosphere. Impurities are removed at various stages of the process. The aluminate solution is filtered, and the alumina crystals that remain as solids are returned to the dissolution process for reuse. Before utilizing the filtered aluminate solution, it is necessary to measure the concentrations of hydroxides (caustic), carbonates, and alumina. This technical document focuses on online monitoring of the concentrations of hydroxides, carbonates, and alumina in the aluminate solution using the temperature titration method of the Metrohm Process Analytics 2060TI Process Analyzer or 2035 Process Analyzer. Online analyzers, process analyzers, inline analyzers.

The 202X Process Analyzer is a compact and easy-to-use online wet chemical analysis process analysis device that enables reliable process monitoring and control around the clock, contributing to time and cost savings. The 202X series includes the following three types: - 2026 Titrator: Ion measurement using titration or ion-selective electrodes (up to 2 lines) - 2026 pH Analyzer: pH measurement with automatic cleaning and automatic calibration functions - 2029 Process Photometer: Absorbance measurement (up to 2 lines)

Cell culture plays a crucial role in monitoring the health of cells in the biopharmaceutical industry. To overcome undesirable side reactions and yield reductions, it is necessary to strictly control this process. This technical document introduces a method for accurately monitoring cell proliferation inside a bioreactor in "real-time." In cell culture, inline process analyzers are a preferred solution to ensure high quality and avoid contamination during measurements. Online analyzers, process analyzers, inline analyzers, Raman spectroscopy.

Research institutions need to expand their ability to routinely analyze candidate microplastics from environmental samples. Spectroscopic techniques are suitable for identifying polymers, as they assist in origin identification and help predict biological impacts. Laboratory Raman spectroscopy is a method that enables rapid identification of polymer materials, serving as an alternative to confocal Raman microscopy and Fourier-transform infrared (FTIR) microscopy. However, very small samples are not suitable for conventional Raman analysis. This application note discusses the use of Raman microscopy for the identification of very small microplastic particles.

Even in customized online industrial processes with multiple parameters and streams, monitoring using ion chromatography becomes possible. The 2060 IC Process Analyzer, based on the 2060 online analysis platform, is a highly flexible and perfect system suitable for online monitoring of ionic compounds in aqueous media at concentrations ranging from ng/L to the % order.

The Metronome Process Analytics 2060 XRF Process Analyzer is a suitable device among online energy-dispersive X-ray fluorescence (EDXRF) spectrometers. Its design philosophy focuses on quality and process management, taking into account multiple sample points and user-friendly operability. It enables online XRF analysis with up to 10 channels.

By using the 2060 Raman analyzer for continuous inline process monitoring, we can deepen our understanding of the process. This ensures consistent product quality by collecting information on every aspect of the manufacturing line without the need to transport samples to the laboratory.