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This document provides tips and tricks for maximizing the use of ultra-fast flow cytometry platforms. In cell-based analysis, flow cytometers remain a powerful tool for providing information at the single-cell level. However, traditional flow cytometers are not designed for the high-throughput data acquisition required in modern drug discovery research, and attempting to apply them directly to research workflows can lead to inefficiencies. This document focuses on the ultra-fast flow cytometry platform, introducing methods to bring biologically relevant insights more easily while significantly improving experimental throughput, including miniaturization of assays for simulation and automation features. [Contents] - Measurement of cells and beads within the same plate well to obtain biologically relevant information - Deconstruction of existing workflows and integration for streamlined analysis - Reduction of sample volume to further enhance experimental flexibility - Rapid data acquisition enabled by templates and automation - Simple workflows and enhanced data analysis insights

The "iQue3" is a high-throughput flow cytometer (cell analyzer) that integrates various traditional experimental methods to deliver results in a short time. The required sample volume for measurement is only 10μL, allowing for significant savings of precious samples and reagents. It simultaneously analyzes the characteristics of suspended cells and secreted proteins in culture supernatants within the same well, providing a dramatically larger amount of information from a single sample measurement.

This document introduces an interview with NBI Health Research Institute (Sapporo City), a biotech venture specialized in the development of monoclonal antibody drugs targeting G protein-coupled receptors (GPCRs). It includes efforts to produce antibodies against GPCRs, including G proteins. [Contents] ■ Controlling information transmission related to diseases ■ Capturing proteins exposed on the extracellular surface ■ High-speed flow cytometry as the key ■ The frontier spirit of Hokkaido blossoms *For more details, please refer to the PDF document or feel free to contact us.

The "iQue High-Throughput Flow Cytometry" is specifically designed for large-scale screening with high throughput, making it an ideal platform for antibody discovery workflows. By integrating rapid data acquisition with powerful analysis software, it enables easy interpretation of multiplex assays and complex datasets. This white paper introduces the use of our product in high-throughput antibody screening and antibody characterization by biopharmaceutical companies such as AbX Biologics, Ablynx (Sanofi), Takeda Pharmaceutical Company, and Avacta Life Sciences. We encourage you to read it. [Contents (partial)] ■ Summary ■ Hybridoma-based antibody discovery ■ Multiplexing of nanobody screening and characterization ■ Multiplexing of specificity and species cross-reactivity ■ IgG titer determination *For more details, please refer to the PDF document or feel free to contact us.

Monoclonal antibodies (mAb), which have made remarkable advancements in molecular engineering and antibody humanization, have become one of the rapidly growing classes of biopharmaceuticals for most clinical applications. In this application note, we introduce how ImmunoPrecise Antibodies utilizes "iQue flow cytometry" in their antibody discovery process. We encourage you to read it. [Contents] ■ Introduction ■ Methods ■ Results and Discussion ■ Conclusion *For more details, please refer to the PDF document or feel free to contact us.

Webinar on Assay Development and Implementation Using the iQue Platform "Use of High-Throughput Flow Cytometry and Bio-Layer Interferometry in Virus Research" is now available for free on demand. In this webinar, we will discuss the challenges of developing and implementing antibody-dependent complement deposition assays using magnetic beads on the iQue platform, and demonstrate their usefulness in measuring functional immunity in convalescent and vaccine samples. *Registration and viewing are available via the link below. Feel free to watch.

An innovative new platform that transforms the cell screening workflow with unparalleled speed, processing power, and ease of use. It can accelerate data analysis for multiplex assays with setup, runtime, and 96 or 384 well configurations. - A redesigned system for clogging and fluid management reduces downtime and supports continuous operation for up to 24 hours. - A more powerful version of the iQue Forecyt software simplifies the entire process with predefined templates and enhanced analytical tools designed for complex datasets.