ビジョンバイオ Product Lineup

Our company develops and sells inspection reagents, offers contract inspection services, and provides support for enhancing quality management value, focusing on these three pillars of our business. We support problem-solving related to food quality management and product development, as well as value creation, with unique products and services such as DNA testing. 【Business Overview】 ■ Development and Sale of Inspection Reagents Rice identification group, meat identification group, foreign matter identification group, etc. PCR experiment kits for schools (Koshihikari identification group (DNA experiment kit)) ■ Contract Inspection Services - Food Inspection Center (food allergy (allergen) testing, etc.) - Foreign Matter Inspection Center (DNA identification, FT-IR, EPMA, etc.) ■ Quality Management and Value Enhancement Support - Seminars and Training (foreign matter identification technology seminars, taste specialist training courses, etc.) - Qualification Exams (foreign matter inspection specialist certification, DNA identification ability certification) *For more details, please contact us or download the catalog.

The features of Vision Bio's recombinant gene testing (ISO compliant) are as follows: ◆ Utilization of ISO/IEC 17025 accredited testing is available We will issue a certificate with an accreditation symbol indicating that this test falls within the scope of ISO/IEC 17025 accreditation. This ensures the effectiveness of international One Stop Testing, making the test results from accredited laboratories internationally valid, transcending differences in countries and systems. ~What is ISO/IEC 17025 accreditation?~ It is an international standard that specifies general requirements for the competence of testing and calibration laboratories. To obtain this standard, it is required not only to have the capability to operate a sound management system but also to demonstrate technical competence and produce valid results. In other words, accredited testing and calibration laboratories are recognized internationally for both their quality management capabilities and technical abilities within the scope of their accreditation.

【Features of Inspection】 ◆ Corresponds to allergen labeling of 27 items in Japan In addition to testing for the 8 specific ingredients, we can also test for 19 items such as "orange," "matsutake," and "gelatin (pork-derived)" that are similar to specific ingredients. ◆ Enhanced inspection system tailored to customer requests We offer a variety of courses, from express testing (2 business days) to more cost-effective options that handle multiple samples (8-10 business days). In case of emergencies, we support quality management in terms of both "speed" and "price" for daily inspections. ◆ "Selectable DNA extraction methods" made possible by Vision Bio's DNA testing In the "PCR method" for detecting DNA, the presence of substances that inhibit testing in samples can affect whether "valid results can be obtained." We allow for the selection of extraction methods based on the type of sample and purpose, ranging from methods compliant with the notification from the Deputy Director of the Consumer Affairs Agency to our original methods that enhance DNA purification while keeping costs down. *For details, please request a catalog or view the PDF data available for download.

Our company offers insect DNA identification testing, which matches the DNA of samples with a database to report the species of insects. 【Features of the Test】 ◆ Overwhelming Number of Species Covered The reference insect DNA database currently contains over 67,000 registered species. Therefore, for major insects, identification is possible by comparing with the registered DNA. Even if a species is not registered, identification at the order or family level is still possible. ◆ High Identification Probability to Solve Customer Issues The identification probability from insects is relatively high at 70% to 80%, and the fresher the sample, the higher the likelihood of successful identification. ◆ Reliable Test Results We report identification results after screening for any inconsistencies in the DNA information. Since some public databases may contain incorrect DNA information, directly listing the five species with the highest match rate can sometimes lead to contradictory results. *For more details, please request a catalog or view the PDF data available for download.

We would like to introduce our company’s "Foreign Object Inspection." We inspect and analyze foreign objects such as hair and metal that may have been mixed in during the manufacturing processes of food, agricultural products, and other items. Through DNA testing and equipment analysis, we can determine the origin and composition of these foreign objects. Additionally, we provide in-house production of testing reagent kits and technical support, offering multifaceted assistance in addressing foreign object contamination. 【Features】 ■ Useful for identifying contamination routes ■ If the foreign object is a biological fragment (plant or animal), comparison with species DNA is possible ■ In-house production of testing reagent kits and technical support is also provided ■ Multifaceted support for addressing foreign object contamination *For more details, please refer to the related link page or feel free to contact us.

Histamine is an active amine produced from the amino acid histidine. Freshness-degraded red fish and fish sauce, in particular, can contain high concentrations of histamine, which can cause a type of food poisoning resembling an allergy known as histamine poisoning. Our company offers food histamine testing to report the histamine concentration in fish meat and its processed products. 【Features of the Test】 ◆ Quantification of "histamine concentration" in the sample Histamine poisoning has been reported to occur when an adult consumes between 22 to 320 mg of histamine. Additionally, the CODEX committee has established that the average histamine concentration in a sample should be below 100 mg/kg as a spoilage standard. Our company quantifies the histamine concentration in food using an enzymatic method. ◆ Use of measurement kits certified by the international certification organization AOAC-RI AOAC-RI is an international organization for the evaluation of analytical methods. Since our company uses measurement kits certified by AOAC-RI PTM, they can also be utilized by customers considering export to overseas markets. *For more details, please request a catalog or view the PDF data from the download section.

【Blood Stain (Blood Detection Test)】 Stains or marks attached to an object are tested to determine whether they are human blood, as well as the gender and blood type. ◆ Human Blood Stain Identification Test Using methods similar to those employed by scientific investigation laboratories (Leucomalachite Green method, Immunochromatography method), we test whether the stain is human blood. ◆ Gender DNA Typing Test Through DNA analysis, we determine whether the sample originates from a male or female. ◆ ABO Blood Type DNA Test Using DNA analysis, we determine the blood genetic type of the sample. *We will report which of the following six types it belongs to. 　　　　≪ Blood Genetic Types ≫ ・Type A → AA type, AO type ・Type B → BB type, BO type ・Type O → OO type ・Type AB → AB type 【Testing Kit: Foreign Substance Identification Group (Blood Stain Identification Reagent)】 No darkroom needed! A simple test to see if the color changes when the reagent is applied determines whether the stain is blood. We use the "Leucomalachite Green method," which has fewer misidentifications than the luminol test.

Our company offers gluten-free confirmation testing for gluten-free foods to report whether they contain gluten found in cereals. 【Features of the Testing】 ◆ Testing compliant with international standards and certifications We offer three types of ELISA kits introduced in CODEX standards and FDA regulations. You can choose the kit based on your purpose and sample. * We recommend selecting the types and number of kits based on the requests from our clients and certification organizations. ◆ Enhanced testing system tailored to customer requests We provide two types of courses: expedited (3 business days) and standard (10 business days). In case of emergencies, we support quality control in daily testing from both "speed" and "cost" perspectives. ◆ Proposal of analytical methods for highly processed foods The FDA warns that advanced degradation of gluten cannot be accurately detected; however, our company also accommodates measurements using the RIDA SCREEN Gliadin Competitive (competitive method) kit, which can compensate for this shortcoming. This method is also listed as an analytical method for highly processed foods in certification standards such as GFCO.

FSSC22000 requires the identification of all potential allergen contamination risks and the establishment and implementation of management methods to reduce or eliminate them. In this context, some companies that have obtained FSSC22000 utilize third-party organizations for the purpose of verifying food safety and confirming its validity. 【Vision Bio's Food Allergy (Allergen) Testing】 Our company, as an ISO/IEC17025 accredited organization (accreditation scope: genetically modified organism testing (soybean qualitative)), participates regularly in external proficiency testing under a quality assurance system that adheres to these standards for food allergy testing. 【Features of the Testing】 ◆ Testing in accordance with the Consumer Affairs Agency's Deputy Director Notification We conduct screening tests (ELISA method) and confirmation tests (PCR method, Western blot method) in accordance with the notification method, which can be used for external certification. ◆ Achieving Reasonable Prices In Course C (Relaxed), we achieve low prices by allowing a longer testing period and processing multiple samples. Testing in accordance with the notification method is available at a lower cost compared to other courses. *For details, please request a catalog or view the PDF data available for download.

Our company offers radiation testing services to measure the levels of radioactive substances in food, soil, fertilizers, and more. 【Features of the Testing】 ◆ Compliance with testing methods notified by the Ministry of Health, Labour and Welfare We conduct tests that comply with the radioactive cesium screening method for food (using NaI(Tl) scintillation spectrometers) and tests that comply with the testing methods for radioactive substances in food (using germanium semiconductor detectors). ◆ Custom requests accommodated Typically, the detection limits are set at "25 Bq/kg," "10 Bq/kg," and "below 10 Bq/kg," but we also accommodate individual requests such as "I want to test at 1 Bq/kg." (The number of testing days and sample volume may vary.) *For more details, please request a catalog or view the PDF data available for download.

Our company offers testing for pesticide residues on fresh agricultural products and processed foods. 【Features of the Testing】 ◆ A variety of original packages tailored to the sample We offer three original packages: "Quarantine Monitoring Package," "Fresh Food Safety Package," and "VB Selected Standard Package." You can choose based on the purpose of the test and the type of sample. ◆ Support for individual tests and the creation of custom packages Individual tests can be conducted for single components. Additionally, we can propose custom packages tailored to customer requests, such as "I only want to test for pesticides that have been used." *For more details, please request a catalog or view the PDF data available for download.

Our company offers contract testing for animal pharmaceuticals on raw materials and processed foods. 【Features of the Testing】 ◆ Packaging of Quarantine Monitoring Items The Ministry of Health, Labour and Welfare formulates an "Import Food Monitoring and Guidance Plan" every year. Based on this, we package the monitoring items for animal pharmaceuticals that are implemented and conduct simultaneous analyses. ◆ Support for Custom Packages from Individual Tests Individual tests can be conducted for single components. Additionally, we can propose custom packages tailored to customer requests, such as "I only want to test animal pharmaceuticals with a usage history." *For more details, please request a catalog or view the PDF data available for download.

Our company offers mycotoxin testing services for agricultural products and processed foods. 【Features of the Testing】 ◆ We address mycotoxins for which provisional residue limits are established under the Food Sanitation Act. We conduct tests for three types of mycotoxins (total aflatoxins, deoxynivalenol (DON), and patulin) that are regulated by the Food Sanitation Act due to their potential contamination of agricultural products and foods. *For more details, please request a catalog or view the PDF data available for download.

◆Genetically Modified Organism Testing (ISO Compliant) ISO/IEC 17025 is an international standard that specifies general requirements for the competence of testing and calibration laboratories. We issue a certificate with an accreditation symbol indicating that this test falls within the scope of ISO/IEC 17025 accreditation. The test results within the accredited scope ensure the validity of international One Stop Testing, making them internationally applicable across different countries and systems. ◆Genetically Modified Organism Testing (Official Method Compliant) In April 2023, with the revision of the genetically modified food labeling system, the Consumer Affairs Agency announced "Testing Methods for Safety-Assessed Genetically Modified Foods" in September 2021. This test is based on these testing methods and can be used as evidence of "no detection of genetically modified organisms" for soybeans distributed domestically.

Our company offers testing for food allergies (allergens) for 8 specific ingredients (7 items) and 19 additional items that are similar. *1 Shrimp and crab are tested as "crustaceans" under one item. *2 The non-compliant item is "ikura." "Gelatin" is only from pork and is available as an optional service. 【Features of the Testing】 ◆ Comprehensive testing for 25 food allergens The 8 specific ingredients (7 items) are tested using the ELISA method (quantitative testing), while the 18 items similar to the specific ingredients (excluding gelatin) are tested using the PCR method (qualitative testing). We primarily receive inquiries regarding plant-based products and curry roux products that claim to be "free from food allergen ingredients." ◆ Optional testing for "gelatin (pork-derived)" available upon request We have independently developed specific detection technology for pork-derived collagen/gelatin. Testing is available using the Western blot method. *For more details, please request a catalog or view the PDF data available for download.

The FDA (U.S. Food and Drug Administration) lists two ELISA kits suitable for final product verification: the Wheat/Gluten ELISA Kit (Morinaga) and RIDA SCREEN Gliadin (R-BioPharm), but it has been noted that these kits cannot accurately detect degraded gluten. Our company also offers testing using the RIDA SCREEN Gliadin Competitive kit (R-BioPharm), which can compensate for this shortcoming. 【Features of the Test】 ◆ A service lineup for highly processed foods An ELISA competitive method designed for fermented and hydrolyzed foods that are assumed to be gluten-free. This test targets peptide fragments of gliadin, secalin, and hordein after hydrolysis, allowing for more accurate testing compared to other ELISA kits. ◆ Tests compliant with international standards and certifications We offer three types of ELISA kits that are introduced in CODEX standards and FDA standards. Kits can be selected according to the purpose and sample.

Our company offers food allergen testing to report the presence or absence of eight specific raw materials and 19 related items (*1). *1 Gelatin is only sourced from pigs. 【Features of the Testing】 ◆ Short turnaround time of 2 to 3 business days We offer a "S Course (3 business days)" and an "Express Test (2 business days)" for urgent needs. We support quality management with a focus on speed through our short turnaround courses. ◆ Testing in accordance with the Consumer Affairs Agency's Deputy Director Notification Testing for specific raw materials is conducted in accordance with the Consumer Affairs Agency notification law, utilizing screening tests (ELISA method) and confirmation tests (PCR method, Western blot method). Additionally, testing for related items is also referenced from the notification law. ◆ Enhanced testing system tailored to customer requests In addition to short turnaround courses, we offer various options, including a cost-effective course (8 to 10 business days) that processes multiple samples. Our flexible service system has received positive feedback from customers for its usability. *For more details, please request a catalog or view the PDF data available for download.

Amid the decline in squid catch volumes, there is growing attention on DNA testing to confirm and certify the ingredient labeling of "squid processed products." Our company offers DNA identification testing for all 22 species of squid. ≪Features of Vision Bio's DNA Testing≫ Point 1: Capable of identifying 46,000 animal species, including seafood! In addition to various seafood, including squid, we also accommodate the identification of various plants and animals. We can meet diverse needs, and we have received positive feedback stating that "in the unlikely event of a discrepancy in labeling, knowing the species name facilitates cause investigation and countermeasures." Point 2: Proven track record in food-specific DNA testing Since the start of rice variety identification testing (DNA analysis) in 2003, we have conducted tests based on 20 years of accumulated experience in DNA testing. We cater not only to raw seafood but also to cooked processed products.

The increase in nut allergies in the country and the need to comply with local labeling regulations when exporting overseas have brought attention to food allergy (allergen) testing for nuts. Our company offers testing for food allergies (allergens) for a total of nine types of nuts. ≪Features≫ - Supports "cashews," which are scheduled to be mandatory for labeling in 2025, and "pistachios," which are recommended for labeling. - Can test a wide range of nuts beyond domestic allergens. - For domestic items, both ELISA (quantitative testing) and PCR (qualitative testing) methods are available. ≪Nuts that can be tested≫ - Walnuts - Almonds - Cashews - Pistachios - Brazil nuts - Hazelnuts - Pecan nuts - Macadamia nuts - Pine nuts

Gelatin is classified as "substitutes for specific ingredients" in food allergen labeling. However, due to its high processing level and the difficulty of DNA detection, a testing method for food allergens had not been established. Therefore, our company focused on pigs, which are representative animals from which gelatin is derived, and developed a technology to specifically detect collagen/gelatin derived from pigs, initiating contract testing for food allergens targeting gelatin (derived from pigs). 【Features of the Test】 ◆ Achieves practical detection sensitivity for food allergen testing! For water (such as wash water or wiping solution), a detection limit of 10 ppm* has been achieved. This matches the detection sensitivity of existing Western blot methods targeting milk and eggs. * For products, the detection limit is 50 ppm. ◆ A rare food allergen test for gelatin in Japan Due to the lack of an established testing method, there are limited testing institutions that can conduct food allergen tests for gelatin. As a result, our company can now conduct tests for "27 items" out of the total 28 items classified as specific ingredients and their substitutes. *For more details, please request a catalog or view the PDF data available for download.

The export value of agricultural, forestry, fishery products, and food has been increasing year by year, surpassing 1 trillion yen for the first time in 2021. On the other hand, there are concerns about the shrinking domestic market in Japan due to population decline in the future. Against this backdrop, some companies dealing with food are already taking steps to focus on overseas markets, strengthening research and development of products for export, or considering how to add value to existing products for export. However, a barrier to overseas exports is compliance with local labeling regulations. Therefore, our company offers testing services not only for allergens that are subject to labeling in Japan but also for those that are required overseas.

Exposure to food allergens through the skin has been reported to trigger food allergy reactions to those foods later on. One of the causes of food allergy onset due to this transdermal sensitization is cosmetics. However, the method widely used for testing food allergens, as notified by the Consumer Affairs Agency, is designed with the premise of targeting food products. Therefore, when testing samples other than food, such as cosmetics, there is a concern that the influence of inhibitory substances not anticipated in food could arise, potentially hindering accurate assessment of the results. In response, our company has accumulated verification data for food allergy (allergen) testing using cosmetics as samples and has established a system to propose testing. 【Technical Documentation Available for Free!】Regarding the application of food allergen testing methods to cosmetic samples To verify whether the food allergen testing method of the Consumer Affairs Agency can also be applied to cosmetic samples, we conducted additive recovery tests. We are currently offering a summary of the results in a technical document for free. ★If you would like the document, please download it from the link below or contact us.

The increase in the number of cases has brought attention to "tree nut food allergies." In the food allergen labeling system, it is planned that by the fiscal year 2025, the labeling of cashew nuts will become mandatory, and the labeling of pistachios will be recommended. Additionally, in many countries and regions abroad, tree nuts are often included in the list of food allergens that must be labeled, which may require compliance when exporting food products. In light of this background, our company has created a collection of basic knowledge for those involved in food quality management and assurance. This knowledge collection covers not only the basic information regarding tree nut food allergen labeling but also introduces ELISA method kits, including those from overseas, presents analysis results of food reactivity, and provides information on test items and methods that can be contracted, all of which will be useful when creating testing plans. 【Table of Contents】 - The environment surrounding tree nut food allergies - Food allergen labeling system and testing methods - How to choose tree nut food allergen tests - Summary of tree nut food allergen testing methods