リタニアルバイオサイエンス List of Products and Services

The co-fermented product Pisara regulates autonomic nervous system activity and promotes digestive function and gastrointestinal motility, improving and preventing constipation and diarrhea. It is expected to result in less odorous stools while simultaneously reducing the smell of flatulence. Additionally, by promoting saliva secretion, it improves the oral environment and is expected to reduce bad breath. 【Features】 ■ Enhances immune function by activating lymphocytes, producing cytokines, and exhibiting antioxidant and anti-allergic effects. ■ Increases resistance to infections (bacteria and mucous spore parasites). ■ Regulates autonomic nervous system activity (promotes digestion and absorption, enhances gastrointestinal motility) → improves constipation and diarrhea. ■ Increases saliva secretion → improves dry mouth and reduces the number of oral bacteria and discomfort in the mouth. ■ Improves the balance of oral and intestinal flora → significantly reduces bad breath, stool odor, and body odor. ■ Patents: "Saliva secretion promoter," "Immune activator," "Infection defense agent," etc. *For more details, please download the PDF or feel free to contact us. ★ "Functional food" testing in progress ★

• Other hygiene related equipment

The symbiotic fermented product Pisara regulates autonomic nervous system activity and promotes digestive function and gastrointestinal motility, improving and preventing constipation and diarrhea. It is expected to result in less odorous stools and simultaneously reduce the smell of flatulence. Additionally, by promoting saliva secretion, it improves the oral environment and is expected to enhance breath freshness. 【Features】 ■ Enhances immune function, activating lymphocytes, producing cytokines, and exhibiting antioxidant and anti-allergic effects ■ Increases resistance to infections (bacteria and mucous spore parasites) ■ Regulates autonomic nervous system activity (promotes digestion and absorption, enhances gastrointestinal motility) → improves constipation and diarrhea ■ Increases saliva secretion → improves dry mouth and reduces the number of oral bacteria and oral discomfort ■ Improves the balance of oral and intestinal flora → significantly reduces bad breath, stool odor, and body odor ■ Patents: "Saliva secretion promoter," "Immune activator," "Infection defense agent," etc. *For more details, please download the PDF or feel free to contact us. ★ "Functional food" testing in progress ★

• Other hygiene related equipment

Our company handles safe "plant-derived functional food ingredients" that are fermented and proliferated using beneficial bacteria in organic rice bran. By promoting saliva secretion, improvements in oral environment issues such as dryness, stickiness, and bad breath can be expected. Additionally, reducing bad breath decreases odor attachment to masks. Furthermore, it is anticipated to regulate autonomic nervous system activity and promote digestion and gastrointestinal motility, contributing to improvements in bowel movements and stool odor. Human clinical trials for functional food labeling (oral care and intestinal regulation) are currently underway. 【Features】 ■ Can be processed into tablets or powders ■ Enhances immune function (lymphocyte activation, cytokine production, antioxidant, anti-allergy effects) ■ Increases resistance to infections (bacteria and mucous spore parasites) ■ Improves dry mouth (reduces oral bacteria count and discomfort in the mouth) ■ Balances oral and intestinal flora (reduces bad breath and stool odor) ★ We are currently seeking development projects using this product. *For more details, please feel free to contact us. You can view the materials for our conventional product "LBS Culture" from the "PDF Download" section.

• Other food and beverage ingredients

The symbiotic fermented product Pisara regulates autonomic nervous system activity and promotes digestive function and gastrointestinal motility, improving and preventing constipation and diarrhea. It is expected to result in less odorous stools and simultaneously reduce the smell of flatulence. Additionally, by promoting saliva secretion, it improves the oral environment and is expected to enhance breath freshness. 【Features】 ■ Enhances immune function, activating lymphocytes, producing cytokines, and exhibiting antioxidant and anti-allergic effects ■ Increases resistance to infections (bacteria and protozoa) ■ Regulates autonomic nervous system activity (promotes digestion and absorption, enhances gastrointestinal motility) → improves constipation and diarrhea ■ Increases saliva secretion → improves dry mouth and reduces oral bacteria and discomfort in the mouth ■ Improves the balance of oral and intestinal flora → significantly reduces bad breath, stool odor, and body odor ■ Patents: "Saliva secretion promoter," "Immune activator," "Infection defense agent," etc. *For more details, please download the PDF or feel free to contact us. ★ "Functional food" testing in progress ★

• Other hygiene related equipment

Our company handles safe "plant-derived functional food ingredients" that are fermented and proliferated using beneficial bacteria and organic rice bran. By promoting saliva secretion, it is expected to improve the oral environment, alleviating dryness, stickiness, and bad breath. Additionally, reducing bad breath decreases odor adherence to masks. Furthermore, it is anticipated to regulate autonomic nervous system activity and promote digestion and gastrointestinal motility, contributing to improvements in bowel movements and stool odor. Human clinical trials for functional food labeling (oral care and intestinal regulation) are currently underway. 【Features】 ■ Can be processed into tablets or powder ■ Enhances immune function (lymphocyte activation, cytokine production, antioxidant, anti-allergic effects) ■ Increases resistance to infections (bacteria and protozoa) ■ Improves dry mouth (reduces oral bacteria count and discomfort in the mouth) ■ Balances oral and intestinal flora (reduces bad breath and stool odor) ★ We are currently seeking development projects using this product. *For more details, please feel free to contact us. You can view the materials for our conventional product "LBS Culture" from the "PDF Download" section.

• Other food and beverage ingredients

Using dentures or mouthguards can lead to an increase in oral bacteria, resulting in stickiness and sliminess, which can cause discomfort. LBS Culture does not "mechanically remove" bacteria like brushing teeth or "sterilize" like mouthwash, but instead focuses on "balancing" the bacteria and promoting saliva secretion to keep the mouth clean and healthy for a long time, improving and preventing issues such as dry mouth, oral stickiness and sliminess, and bad breath. 【Features】 ■ Increased saliva secretion activity → Improves dry mouth and reduces the number of oral bacteria and discomfort in the mouth ■ Improved balance of oral and intestinal flora → Significantly reduces bad breath, fecal odor, and body odor ■ Regulation of autonomic nervous system activity (promoting digestive absorption function and gastrointestinal motility) → Improves constipation and diarrhea ■ Patents: "Saliva secretion promoter," "Immune activator," "Infection defense agent," etc. *For more details, please download the PDF or feel free to contact us. ★ "Functional food" testing in progress ★

• Other bio-related products

LBS culture has been announced at the Japanese Society of Oral Medicine to have the effect of reducing hydrogen sulfide and methyl mercaptan, which are causes of bad breath. By promoting saliva secretion, the oral environment during sleep is improved, which is expected to lead to better breath and prevention of colds, thus contributing not only to the health of individuals but also significantly improving the environment in caregiving settings. 【Features】 ■ Enhances immune function, activating lymphocytes, producing cytokines, and exhibiting antioxidant and anti-allergic effects ■ Increases resistance to infections (bacteria and mucous spore parasites) ■ Regulates autonomic nervous activity (promotes digestive absorption and gastrointestinal motility) → improves constipation and diarrhea ■ Enhances saliva secretion → improves dry mouth and reduces the number of oral bacteria and discomfort in the mouth ■ Improves the balance of oral and intestinal flora → significantly reduces bad breath, fecal odor, and body odor ■ Patents: "Saliva secretion promoter," "Immune activator," "Infection defense agent," etc. *For details, please download the PDF or feel free to contact us. *The effects of reducing bad breath and promoting saliva secretion have been confirmed through testing at Tsurumi University School of Dentistry. ★ "Functional food" testing is currently underway ★

• Food/beverage functional materials

In the field of nursing care, managing odors and the effort involved in bowel care and oral care is one of the major challenges. Caregivers, as well as the users themselves, often express discomfort regarding these issues. LBS Culture helps improve and prevent constipation and diarrhea by regulating autonomic nervous system activity and promoting digestive function and gastrointestinal motility. This leads to the production of less odorous stools, making bowel management significantly easier. Additionally, by promoting saliva secretion, it improves the oral environment, which can help reduce bad breath and prevent colds, greatly contributing to the improvement of the care environment. 【Features】 ■ Enhances immune function, activating lymphocytes, producing cytokines, and exhibiting antioxidant and anti-allergic effects ■ Increases resistance to infections (bacteria and mucous cysts) ■ Regulates autonomic nervous system activity (promotes digestive absorption and gastrointestinal motility) → improves constipation and diarrhea ■ Enhances saliva secretion → alleviates dry mouth and reduces the number of oral bacteria and discomfort in the mouth ■ Improves the balance of oral and intestinal flora → significantly reduces bad breath, stool odor, and body odor ■ Patents: "Saliva secretion promoter," "Immune activator," "Infection defense agent," etc. ★ "Functional food" testing in progress ★

• Other hygiene related equipment

We would like to introduce feedback from users who have used our plant-based, safe, and secure functional food ingredient 'LBS Culture,' which is derived from a microbial community fermented and proliferated with rice bran, in aquaculture fish. The microbial community that produces this product has been identified by a third-party testing organization through biochemical property analysis, DNA sequencing analysis, and BLAST search. Additionally, its application range extends widely beyond humans to include livestock, pets, fish, and plants. 【User Feedback】 ■ Increased appetite, grew strong bones, became more active, and improved growth rate ■ Effective in preventing infections (bacterial and myxozoan) ■ Aquariums become less dirty, and water odor decreases ■ Improved feed conversion rate ■ Reduced use of chemicals *For more details, please refer to the PDF document or feel free to contact us. ★ "Functional Food with Health Claims" testing in progress ★

• Food/beverage functional materials

We would like to share feedback from users who have used our plant-based, safe, and secure functional food ingredient 'LBS Culture', which is fermented and proliferated using rice bran, in horseback riding. This product is cultured in a medium that combines rice bran extract with glucose. The rice bran used is sourced from organic JAS rice produced through natural farming methods in Shiga Prefecture. Additionally, LBS Culture has received approval from the Ministry of Agriculture, Forestry and Fisheries as "fermented rice bran feed" based on the Feed Safety Law. 【User Feedback】 ■ Appetite remains strong even in summer; they eat well. ■ Symptoms of colic, such as constipation and intestinal torsion, rarely occur. ■ The smell of feces decreases within a few days. ■ After about a month of feeding, the coat becomes shinier. ■ Irritability decreases, and calmness increases. *For more details, please refer to the PDF document or feel free to contact us. ★ "Functional Food with Health Claims" testing in progress ★

• Food/beverage functional materials

We would like to introduce feedback from users who have used our plant-based, safe, and secure functional food ingredient 'LBS Culture,' which is fermented and proliferated using rice bran, in breeding hens, laying hens, and broilers. The microorganisms that create this product have been identified by third-party testing institutions through biochemical property analysis, DNA sequencing analysis, and BLAST searches. The application range of LBS Culture extends widely beyond humans to livestock, pets, fish, and plants. 【User Feedback】 ■ Increased appetite, even during summer ■ Improved growth rate with three weeks of feeding after hatching ■ When given to breeding hens, hatching rates improved, and chicks grew very robustly ■ Fecal odor significantly reduced within a few days, and the unpleasant smell in the chicken coop was eliminated within a month ■ Egg whites and yolks became more prominent, and egg quality improved ■ Late-stage feeding of broilers showed a deterioration in feed conversion rate ■ Reduced use of antibiotics, and the fertilizing effect of chicken manure improved *For more details, please refer to the PDF document or feel free to contact us. ★ "Functional Food Labeling" testing in progress ★

• Food/beverage functional materials

We would like to share feedback from users who have used the plant-based, safe, and secure functional food ingredient 'LBS Culture,' which is fermented and proliferated using rice bran, on sows and piglets. This product has undergone safety testing, including acute toxicity tests using ICR mice, the Ames test for mutagenicity, eye irritation tests, human patch tests, and skin sensitization tests, confirming its safety for humans and animals. 【User Feedback】 ■ Eaten well even in summer, particularly effective for maintaining the health of sows during pregnancy. ■ Surprised that it prevents diarrhea in piglets. ■ The smell of feces and urine decreases within a few days, and the odor in the barn reduces in about a month. ■ Feeding sows increases the number of piglets born and improves the growth rate of piglets. ■ Coat quality improves, and they become calmer. ■ The incidence of pneumonia and nephritis in sows decreases, and piglets grow up healthy. ■ Reduction in the use of pharmaceuticals. *For more details, please refer to the PDF document or feel free to contact us. ★ "Functional Food with Health Claims" testing in progress ★

• Food/beverage functional materials

We would like to introduce feedback from users who have used the plant-based, safe, and secure functional food ingredient 'LBS Culture,' which is derived from fermented and proliferated microorganisms using rice bran, in Japanese beef (breeding and fattening). This product is manufactured by high-pressure sterilization of a cultured microbial mixture at 121°C for 17 minutes, so it does not contain live bacteria. The raw liquid is light gray to light brown and has a slight characteristic fermentation odor. 【User Feedback】 ■ Increased appetite for both parents and offspring. Mixed with milk for the calves, resulting in improved growth rates. ■ Improves and prevents diarrhea in calves. ■ Significant reduction in the smell of manure and livestock barns, with no complaints from neighboring residents. ■ Suppresses the occurrence of houseflies and enhances the effectiveness of compost. ■ Prevents diarrhea and colds believed to be caused by stress during transport and other situations. ■ Faster healing of wounds after dehorning. *For more details, please refer to the PDF document or feel free to contact us. ★ "Functional Food with Health Claims" testing currently underway ★

• Food/beverage functional materials

We would like to introduce feedback from users who have used our plant-based, safe, and secure functional food ingredient 'LBS Culture', which is fermented and proliferated using rice bran, on dairy cows. This product is cultured in a medium that combines rice bran extract with glucose. The rice bran used is derived from organic JAS rice grown through natural farming methods in Shiga Prefecture. 【User Feedback】 ■ The amount of feed intake that typically decreases in summer has actually increased. ■ Recovery of the uterus is faster, and the renewal rate has decreased. ■ Diarrhea in calves has improved and been prevented, and colds no longer spread throughout the barn. ■ The disease rate has decreased. ■ The odor of manure and urine has drastically reduced within 4 to 5 days, making urine management easier. ■ The protozoa in the rumen have become larger and more active. ■ After about 4 months, mastitis has decreased along with a reduction in somatic cell count, and when it does occur, the symptoms are mild. ■ Since it does not contain live bacteria, it is easy to add to mixed feed. *For more details, please refer to the PDF document or feel free to contact us. ★ "Functional Food with Health Claims" testing in progress ★

• Food/beverage functional materials

As of July 1, 2018, two types of antibiotics, "sulfamethazine" and "virginiamycin," which have been used as growth promoters mixed into animal feed, will be banned. Many may be looking for alternatives to these antibiotics and antimicrobials. LBS Culture is a plant-based, safe, and secure functional food ingredient made by fermenting and proliferating microbial groups with rice bran. It is gladly utilized by those who want to promote disease prevention and growth in livestock safely and securely without relying on antimicrobial feed additives. 【Biological Function Improvement Effects (Research Results)】 ■ Enhances immune function, activating lymphocytes, producing cytokines, and exhibiting antioxidant and anti-allergic effects. ■ Increases resistance to infections (bacteria and coccidia). ■ Regulates the autonomic nervous system, enhancing digestive fluid secretion, promoting gastrointestinal peristalsis, relaxing blood vessels, and suppressing itching. ■ Improves the balance of intestinal flora, creating a gut environment dominated by beneficial bacteria, thus promoting digestion. ■ In dairy cows, the rate of mastitis decreases, and the somatic cell count in milk (an indicator of mastitis) also decreases. ■ The odor of livestock feces and urine significantly reduces within a few days. ★ "Functional Food with Health Claims" testing in progress ★

• Food/beverage functional materials

When it comes to oral care, many people may imagine brushing their teeth with a toothbrush or using mouthwash. These common forms of oral care only provide temporary improvements to the oral environment and do not offer long-lasting effects, especially during sleep. LBS Culture does not mechanically remove bacteria like brushing or kill them like mouthwash; instead, it focuses on "balancing" the bacteria and promoting saliva secretion to keep the mouth clean and healthy for an extended period. It helps improve and prevent issues such as dry mouth, oral stickiness, and bad breath. Furthermore, it enhances the digestive absorption capacity of the gastrointestinal tract and balances intestinal bacteria, thereby improving the gut environment. This addresses one of the causes of bad breath, known as "foul odor from the intestines," which can improve in just a few days. We encourage you to utilize LBS Culture in the development of entirely new oral care products. 【Features】 ■ Increased saliva secretion → Improves dry mouth and reduces the number of oral bacteria and discomfort in the mouth ■ Balancing oral and intestinal flora → Significantly reduces bad breath, fecal odor, and body odor ■ Regulation of autonomic nervous system activity (promoting digestive absorption and gastrointestinal motility) → Improves constipation and diarrhea ■ Patents: "Saliva secretion promoter," "Immune activator," "Infection defense agent," etc. ★ "Functional food" testing in progress ★

• Other bio-related products

LBS culture is a functional food ingredient that can be processed into tablets or powders, and is also usable in cosmetics and soaps such as creams and lotions for external application. With nearly 30 years of food experience, there have been no reports of side effects, and it has been confirmed that it is not related to toxicity, body temperature, blood pressure, antioxidant levels, salivary amylase, or salivary redox potential. 【Features】 ■Improvement of oral and intestinal flora balance → Significant reduction in bad breath, fecal odor, and body odor ■Increased saliva secretion activity → Reduces the number of oral bacteria, decreases oral discomfort → Maintains a good oral environment ■Promotes digestive absorption function and gastrointestinal motility → Improves constipation and diarrhea → Increases appetite ■Patents: "Saliva secretion promoter," "Immune activator," etc. *For more details, please refer to the catalog or feel free to contact us. ★ "Functional food with health claims" testing in progress ★

• Food/beverage functional materials

"LBS Culture" is a safe and secure functional food ingredient that is fermented and proliferated using organic rice bran. It enhances the digestive absorption function of the gastrointestinal tract, balances the bacteria in the intestines, and improves the intestinal environment, thereby addressing not only issues with bowel movements such as diarrhea and constipation but also improving "bad odors from the intestines," which is one of the causes of bad breath, in just a few days. 【Features】 ■ Improves the balance of intestinal and oral flora → Significantly reduces bad breath, stool odor, and body odor ■ Promotes digestive absorption function and gastrointestinal motility → Improves constipation and diarrhea → Enhances health ■ Increases saliva secretion activity → Reduces the number of oral bacteria, decreasing discomfort in the oral cavity → Maintains a healthy oral environment ■ Patents: "Saliva Secretion Promoter," "Immune Activator," etc. *For more details, please refer to the catalog or feel free to contact us. ★ "Functional Food with Health Claims" testing in progress ★

• Food/beverage functional materials

LBS culture has nearly 30 years of food experience with no reports of side effects, and it has been confirmed that it does not relate to toxicity, body temperature, blood pressure, antioxidant levels, salivary amylase, or salivary oxidation-reduction potential. 【Features】 ■ Increased salivary secretion activity → Reduces the number of oral bacteria, decreases discomfort in the oral cavity → Maintains a good oral environment ■ Promotes digestive absorption function and gastrointestinal motility → Improves constipation and diarrhea → Increases appetite ■ Improves the balance of oral and intestinal flora → Significantly reduces bad breath, fecal odor, and body odor ■ Patents: "Salivary secretion promoter," "Immune activator," etc. *For more details, please refer to the catalog or feel free to contact us. ★ "Functional Labeling Food" testing in progress ★

• Food/beverage functional materials

LBS culture has nearly 30 years of food experience with no reports of side effects, and it has been confirmed that it does not relate to toxicity, body temperature, blood pressure, antioxidant levels, salivary amylase, or salivary oxidation-reduction potential. 【Features】 ■ Increased salivary secretion activity → Reduces the number of oral bacteria, decreases discomfort in the oral cavity → Maintains a good oral environment ■ Promotes digestive absorption function and gastrointestinal motility → Improves constipation and diarrhea → Increases appetite ■ Improves the balance of oral and intestinal flora → Significantly reduces bad breath, fecal odor, and body odor ■ Patents: "Salivary secretion promoter," "Immune activator," etc. *For more details, please refer to the catalog or feel free to contact us. ★ "Functional Food Labeling" testing in progress ★

• Food/beverage functional materials

LBS culture has a suppressive effect on sympathetic nerve activity in the skin. When sympathetic nerve activity is heightened, symptoms such as cold sensitivity, swelling, and delayed wound healing occur. It has been demonstrated through experiments using rats that by consuming LBS culture and weakening sympathetic nerve activity, blood vessels can relax and expand, thereby increasing blood flow. By applying LBS culture to the skin (mucous membranes) and suppressing sympathetic nerve activity in the skin, it promotes vascular relaxation and expansion, and effects such as strengthening of the gums and mucous membranes, alleviation of swelling and edema, and promotion of wound healing (such as for oral ulcers) are expected. 【Features】 ■ Increased blood flow to the skin ■ Increased oxygen and nutrient supply to the skin ■ Strengthening of gums and mucous membranes ■ Alleviation of swelling and edema ■ Suppression of periodontal disease ■ Promotion of wound healing (oral ulcers) *For more details, please refer to the catalog or feel free to contact us. ★ "Functional Food" testing in progress ★

• Food/beverage functional materials

LBS culture has the effect of improving the oral environment. Fifteen individuals aged 20 to 50 were asked to consume one jelly containing LBS culture once a day, and after monitoring changes in their mouths, responses indicated that after one month, issues such as throat pain and oral stickiness were no longer a concern. Additionally, a clinical trial was conducted on healthy men and women, who took LBS culture-containing tablets twice a day for one month. The number of bacteria on the tongue, as well as the properties of saliva and blood, were quantitatively measured, revealing a significant reduction in oral bacteria. It was also recognized that LBS culture has effects in alleviating and preventing dry mouth symptoms and reducing bad breath, thereby improving the oral environment. 【Improvement Effects】 ■ Improvement of oral stickiness ■ Alleviation and prevention of dry mouth symptoms ■ Significant reduction in the number of bacteria on the tongue ■ Reduction of bad breath ■ Potential suppression of cavities and periodontal disease ■ Ability to improve the oral environment without using disinfectants *For more details, please refer to the catalog or feel free to contact us. ★ "Functional Food" testing in progress ★

• Food/beverage functional materials

By consuming LBS culture, it is possible to increase the activity of the vagus nerve (parasympathetic nerve). A total of 60 people, both those concerned about their intestinal health and those who are not particularly concerned, were asked to try a supplement containing LBS culture for one month. A survey was conducted after the trial regarding changes in their intestinal condition, and it was found that many people experienced improvements in their intestinal health after the trial. **Main effects of LBS culture on intestinal environment improvement:** - Promotion of gastrointestinal peristalsis - Enhancement of the intestinal digestive and absorption capacity - Improvement of intestinal flora balance and maintenance of a good intestinal environment under conditions of Westernized eating habits and high stress - Improvement of constipation and diarrhea, leading to easier passage of less odorous stools *For more details, please refer to the catalog or feel free to contact us.* ★ "Functional Food" testing in progress ★

• Food/beverage functional materials

By consuming LBS culture and enhancing the activity of the parasympathetic nervous system in the digestive tract, it is possible to maintain a better oral environment. An experiment administering LBS culture into the stomachs of rats showed an increase in the activity of the vagus nerve (parasympathetic nervous system). As the activity of the vagus nerve is promoted, the oral and intestinal environments are improved, leading to enhanced health. 【Features】 ■ Increased saliva secretion → Reduced discomfort in the mouth → Maintenance of a good oral environment ■ Promotion of gastrointestinal motility → Enhanced digestive absorption ability → Intestinal regulation effect → Increased appetite ■ Health promotion *For more details, please refer to the catalog or feel free to contact us. ★ "Functional Labeling Food" testing in progress ★

• Food/beverage functional materials

"LBS Culture" is a safe and secure functional food ingredient that is fermented and proliferated using organic rice bran. It is a microbial group that has been passed down as traditional food, beverages, and health-promoting foods in both Japanese and Western cultures, characterized by the absence of strong fermentation odors or sourness like those found in yogurt or natto. Additionally, it can be concentrated after high-temperature heating of the microorganisms and metabolites, and processed into tablets or powders, making it highly versatile. 【Features】 ■ Safe and secure functional food ingredient ■ All plant-derived, including the culture medium *For more details, please download the PDF or feel free to contact us. ■ No strong fermentation odors or sourness ■ Highly versatile *For more details, please refer to the catalog or feel free to contact us. ★ "Functional Food with Health Claims" testing in progress ★

• Food/beverage functional materials