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  3. 東ソー バイオサイエンス事業部 計測分野
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東ソー バイオサイエンス事業部 計測分野

number of employees12595
addressTokyo/Chuo-ku/2-2-1 Yaesu, Tokyo Midtown Yaesu, Yaesu Central Tower
phone03-6636-3733
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last updated:Apr 16, 2024
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HPLC column (bio) HPLC column (bio)
Ion chromatography Ion chromatography
GPC system and GPC column GPC system and GPC column
HPLC column (general) HPLC column (general)
Divided use filling agent TOYOPEARL series Divided use filling agent TOYOPEARL series
Divided

Divided use filling agent TOYOPEARL series

We offer a series of packing materials for preparative use to meet various purification needs. 〇 Separation modes - Size exclusion chromatography - Ion exchange chromatography - Hydrophobic chromatography - Affinity chromatography - Mixed-mode chromatography We also provide pre-packed columns for process development, from lab scale to manufacturing scale.

TOYOPEARL Comprehensive Catalog

A list of TOYOPEARL fillers and their features is available!

This catalog is a comprehensive guide to the hydrophilic polymer packing material "TOYOPEARL," suitable for chromatography from lab scale to production scale. We offer types with average particle diameters of 35μm (some at 30μm), 65μm (some at 75μm), and 100μm, allowing you to use them according to your needs for initial purification, intermediate purification, and high-resolution separation processes. [Contents] ■ Product Overview ■ Size Exclusion Chromatography ■ Ion Exchange Chromatography ■ Hydrophobic Chromatography ■ Mixed-Mode Chromatography ■ Affinity Chromatography ■ Usage and Packing Methods for TOYOPEARL *For more details, please refer to the PDF document or feel free to contact us.

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『TOYOPEARL AF-rProtein L-650F』

Protein L affinity chromatography packing material!

"TOYOPEARL AF-rProtein L-650F" is a packing material for protein L immobilized affinity chromatography for the purification of antibodies and fragment antibodies containing light chains. Compared to existing commercial products, the adsorption capacity and alkali resistance have been significantly improved. Additionally, it enables affinity purification of antibodies that do not have an Fc region, which cannot be applied with protein A packing materials. 【Features】 ■ Novel recombinant protein L ligand immobilization ■ Improved adsorption capacity and alkali resistance compared to existing commercial products ■ High mechanical strength ■ Usable at high flow rates ■ Easy to scale up *For more details, please refer to the catalog or feel free to contact us.

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[Technical Data] Chromatography of Antibody Drugs (Separation Purification/Quality Control)

This is a technical document/catalog regarding the separation, purification, and quality control of antibody pharmaceuticals using chromatography.

This document is the product catalog for TOYOPEARL and TSKgel series. In "Process Chromatography for Antibodies," we present the characteristics of various chromatography separation modes, as well as key TOYOPEARL products for antibody purification, using tables. Furthermore, the product list categorizes numerous products under each item. [Contents (Excerpt)] <TOYOPEARL> ■ Process Chromatography for Antibodies Characteristics of various chromatography separation modes Key TOYOPEARL products for antibody purification Protein A and Protein L carriers Ion exchange carriers ■ Product List (Process Chromatography) *For more details, please refer to the PDF document or feel free to contact us.

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Technical Data: Bioseparation Handbook

A comprehensive explanation of various separation modes, their principles, characteristics, and more, covering a wide range from the basics to actual measurements.

This document is a technical material that explains liquid chromatography. Liquid chromatography has become an essential method for the separation and analysis of biological samples. This guide provides a comprehensive explanation of various separation modes of liquid chromatography, their principles, and features, ranging from the basics to actual measurements. [Contents (excerpt)] - Properties of proteins and nucleic acids - Separation methods for biopolymers - Liquid chromatographs used for measuring biopolymers - Size exclusion chromatography - Ion exchange chromatography *For more details, please refer to the PDF document or feel free to contact us.

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Screening/Purification Prepackaged Column SkillPak Series

It is a column filled with a carrier used for chromatographic purification of proteins and other substances.

SkillPak is a column filled with various TOYOPEARL, TSKgel PW series, and Ca++Pure-HA. The 1 mL and 5 mL types, which can be connected to general-purpose liquid chromatography systems with 1/16" size piping, are suitable for screening filling materials and method development. The 50 mL and 200 mL types feature flange connections and can be used for purification at a few grams scale and considerations for scale-up.

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Alkali-resistant protein A affinity filler

Elution can be performed under mild pH conditions, controlling acid denaturation! Reduced renewal costs due to high alkali durability! Applicable to IgM and mouse IgG as well!

"TOYOPEARL Super A" is a chromatography packing material for antibody purification that immobilizes genetically engineered Protein A. It has a high antibody adsorption capacity and alkali resistance, enabling the construction of an efficient and robust antibody purification process. Additionally, it allows elution under mild pH conditions, possesses excellent mechanical properties, and demonstrates good flow characteristics. 【Features】 ■ High antibody adsorption capacity (over 68g/L) ■ High alkali durability (compatible with 0.5mol/L NaOH cleaning) ■ Elution possible under mild pH conditions ■ Excellent mechanical properties and good flow characteristics *For more details, please refer to the PDF document or feel free to contact us.

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