ショーシンEM List of Products and Services

The "CytoSMART Omni FL" is a live cell imager that allows you to monitor experiments and analyze data in real-time, anytime and anywhere. It can be used for time-lapse imaging and endpoint assay experiments with live cells in a cell culture incubator, utilizing brightfield and two-wavelength fluorescence channels (green and red). Its intuitive and open design not only makes the device easy to use and maintain but also allows for integration into established automated workflows. 【Features】 ■ Innovative cloud-based storage and data analysis ■ Incubator-friendly ■ Plug and play ■ Automation compatible ■ High-throughput fluorescence & brightfield imaging *For more details, please refer to the PDF document or feel free to contact us.

• Imaging and image analysis equipment

Spheroid cell culture has emerged as a powerful in vitro tool for tumor treatment research. The proliferating cells in the 3D tumor spheroids are shown with green fluorescence labeling. The red fluorescence labeling represents the drugs injected into the tumor spheroids. *For more details, please refer to the related links or feel free to contact us.*

• Microscope
• Other microscopes and optical inspection equipment

The stage top chamber is compatible with the XY stage of the microscope or piezo insert, connects to Okolab's temperature, gas, and humidity controllers, and creates an appropriate environment for live cell imaging on the microscope stage. With compatible magnetic inserts, it can accommodate Petri dishes, slides, and MW plates. The magnetic lock holds Petri dishes, slides, and MW plates in the correct position within the chamber. 【Features】 ■ Temperature range: 3°C above ambient temperature to 60°C or below ■ Temperature accuracy - ±0.1°C in sample feedback mode - ±0.3°C in chamber feedback mode ■ Compatibility: Bold Line T, UNO Combined, and H401-T controllers * You can download the English version of the catalog. * For more details, please refer to the PDF materials or feel free to contact us.

• Culture Equipment
• Other Culture
• Other microscopes and optical inspection equipment

The "LAMBDA10" automatically controls multiple filter wheels and mechanical shutters with a single controller, supporting multi-color, time-lapse, and ratio imaging. The wavelength switching time is 30 msec (4-position wheel). Adapters are available for mounting the filter wheels on the excitation and fluorescence sides of each microscope. 【Features】 ■ Wavelength switching time is 30 msec (4-position wheel) ■ Control of up to 3 filter wheels and 2 shutters ■ Filter sizes are 25mm, 32mm, and 50mm ■ 7 levels of speed adjustment *For more details, please refer to the PDF document or feel free to contact us.

• Other microscopes and optical inspection equipment
• others

The "LAMBDA TLED" is a microscope LED light source that allows for light intensity adjustment from a controller and can perform on-off switching with a rise time of 25μsec using TTL signals for external control. It has a lifetime of over 50,000 hours with stable output. Additionally, it is equipped with high-output LEDs suitable for fluorescence observation, and we offer "TLED+" which allows external control of light intensity via analog input, as well as "TLED-DC" which can combine two TLED+ heads and be mounted on a coaxial optical path. 【Features】 ■ Lifetime > 50,000 hours ■ On-off time < 25μsec ■ TTL control ■ Stable output ■ Easy setup *For more details, please refer to the PDF document or feel free to contact us.

• Light source/lighting

The "LAMBDA DG-4" features dual galvanometers that can switch the interference filter in the optical path with a time resolution of 0.5 msec. It can introduce white light into the microscope in the through position. It enables time resolution and narrow-band wavelength excitation that conventional filter wheel and monochromator methods cannot achieve. 【Features】 ■ Wavelength switching time is 0.5 msec ■ High output with a 300W xenon light source ■ Multi-wavelength excitation ■ Suitable light source for Fura-2 calcium indicator *For more details, please refer to the PDF document or feel free to contact us.

• Light source/lighting

"LumiCycle" can fully automate long-term luminescence measurements of active cells containing luciferase genes from genetically modified animals in a high-throughput manner. Active cells cultured in a 35mm petri dish are set on a turntable, and the luminescence emitted from the expressing cells is counted using photon counting. The control of the turntable and photon counting is fully automated, allowing users to perform luminescence measurements from numerous samples with a simple system setup and operation, enabling the analysis of circadian rhythms. 【Features】 ■ Design that fits standard incubators ■ Maintains appropriate temperature and humidity by circulating the incubator's air within the chamber ■ Allows for long-term measurements under stable conditions ■ Enables analysis of circadian rhythms *For more details, please refer to the PDF document or feel free to contact us.

• Other Analysis
• Culture Equipment
• Other analytical and testing equipment

"Lumazone" is an imaging system that allows for consistent real-time observation of live cells, in vitro, and in vivo, utilizing fluorescent proteins and bioluminescence information expressed from living plants and small animals, all from a single device. It employs a high-sensitivity CCD camera, a light-tight dark box with excellent light shielding, a unique optical system and lighting device, as well as advanced software for data analysis. The use of fluorescent reagents and fluorescent proteins (such as GFP and RFP) enables fluorescent staining based on cell tissues and proteins, making it ideal for experiments that observe changes in intracellular localization in real-time with multi-color capabilities. **Features** - High-sensitivity detection of bright field, fluorescent proteins, and luciferase expression - Diverse optical systems for Live Cell to in vivo macro observation - Real-time observation of the progression of individual small animals - Equipped with a low-noise, high-sensitivity CCD camera covering a wide range from ultraviolet to near-infrared - Real-time high-sensitivity detection using EM CCD technology *For more details, please refer to the PDF materials or feel free to contact us.*

• Other Analysis
• Analytical Equipment
• Other measurement and measuring equipment

The "HoloMonitor M4" can display time-lapse data of cells obtained within a CO2 incubator as a true 3D image, leveraging its deep focus depth feature. Since it does not require fluorescent staining, sample preparation is simple and setup is easy. It also allows for low-oxygen experiments, and the characteristics of the cells obtained as numerical data can be easily analyzed using patented software. 【Features】 ■ Visualize and quantify cellular events ■ Efficient operability and reliability ■ Ideal for cell movement research ■ Gentle on cells and compatible with incubators ■ Enables long-term experiments *For more details, please refer to the PDF materials or feel free to contact us.

• Other Analysis
• Other analytical and testing equipment
• Image Cytometer

"CELENA X" is an intelligent solution suitable for the rapid acquisition and analysis of high-quality high-content images. It integrates full automation for 6 to 1536 well plate imaging and slide scanning into a single system. It is equipped with the capability to acquire and quantify cellular information from both fixed and live cells, making it a useful tool not only for life sciences research but also for drug discovery and development. 【Features】 ■ Designed to minimize setup work and improve operational efficiency ■ Powerful and flexible software ■ Capable of quantitatively analyzing numerous cellular functions ■ A useful tool for drug discovery and development *For more details, please refer to the PDF document or feel free to contact us.

• Other Analysis
• Cell Analysis Software
• Other analytical and testing equipment

"Retiga LUMO" is a cooled CCD camera for bioluminescence imaging. It minimizes dark current and readout noise that interfere with the detection of extremely weak emissions, enabling high-sensitivity detection with a high quantum efficiency CCD. To accommodate various applications, the output from the CCD is processed by a 50MHz dual-port digitizer, achieving high frame rates, and is transferred to a computer via a USB 3.0 interface. 【Features】 ■ Quick focus adjustment and the ability to minimize photobleaching of samples ■ Compatible with microscope fluorescence observation applications and highly expandable ■ Electronic cooling allows for noise-free imaging even during long exposures ■ Scientific-grade interline CCD with a maximum quantum efficiency of 75%, capturing sCMOS *For more details, please refer to the PDF materials or feel free to contact us. *You can download the English version of the catalog.

• Other microscopes and optical inspection equipment
• Other Sensors
• Other measurement and measuring equipment

The "RETIGA R Series" is a compact scientific digital camera that implements new technology CCDs. It offers excellent cost performance, making it suitable for research purposes in various industries and life sciences. It provides tools for fast, accurate, and high-sensitivity imaging with plug-and-play capability. 【Features】 ■ Achieves high frame rates with a 50MHz dual-port digitizer output from the CCD ■ Allows for quick focusing and minimizes photo bleaching on samples ■ Enables noise-free imaging even with long exposure times due to electronic cooling ■ Comes with OCULAR imaging software *For more details, please refer to the PDF materials or feel free to contact us.

• Other Sensors
• Other measurement and measuring equipment
• Other microscopes and optical inspection equipment

The "CytoSMART Lux3 FL" is a compactly designed automatic fluorescence live cell imaging microscope that allows observation in a controlled environment within a cell culture incubator using bright field and two wavelength fluorescence channels (green and red). By acquiring high-quality images to create real-time time-lapse movies and snapshots, it is possible to track specific and dynamic cellular processes. 【Features】 ■ Bright field digital phase contrast and two wavelength fluorescence imaging ■ Monitoring cell culture in a stable environment within the cell culture incubator ■ Complete remote access without the need to visit the laboratory for each inspection of cell culture ■ Email alerts for abnormalities in cell culture ■ Development of cellular processes through time-lapse movies ■ Easy expansion of multiple device setups with a single computer *For more details, please refer to the related links or feel free to contact us.

• Microscope
• Other microscopes

The "CytoSMART Lux3 BR" monitors the environment and cell culture conditions in the incubator on your behalf, providing real-time time-lapse and snapshots. If any abnormalities occur, it will immediately send a warning message to your smartphone, tablet, or computer via email, whether you are in the lab, at the office, or at home. 【Features】 ■ Acquire high-quality images necessary for data analysis and papers ■ Analyze cells in the best culture environment ■ Access the application anytime you need (cell confluence, scratch analysis, colony detection, and more) ■ Live cell imaging that is friendly to the incubator ■ Complete remote access without having to go to the lab for each cell culture inspection ■ Easy expansion of multiple device setups on a single computer *For more details, please refer to the related links or feel free to contact us.

• Microscope
• Imaging and image analysis equipment

The "CytoSMART Omni" is an automated live cell imager that fits inside a standard CO2 incubator. With a high-resolution camera and transmitted light LED illumination that moves along the platform, it captures the entire area of the culture vessel, allowing for monitoring of all cell cultures and enhancing spatial resolution for the study of biological processes. 【Features】 ■ Visualizes all cells in the culture vessel with wide-area scanning ■ Acquires high-quality images necessary for data analysis and publications ■ Analyzes cells in the best culture environment ■ Access to the application anytime, anywhere as needed (cell confluence, scratch analysis, colony detection, and more) ■ Incubator-friendly live cell imaging ■ Complete remote access without the need to visit the lab for every cell culture inspection *For more details, please download the PDF or feel free to contact us.

• Other Analysis
• Image Cytometer
• Other cell research

We handle the high-content imaging system 'CELENA(R) X' manufactured by Logos Biosystems. The 'CELENA(R) X' allows for the quantitative analysis of numerous cellular functions, from fixed cell assays to more complex time-lapse live cell assays, by setting up advanced image analysis sequences with powerful and flexible software. 【Features】 ■ Fully automated plate and slide imaging ■ Interchangeable filter cubes and objective lenses ■ Powerful and user-friendly interface ■ Laser autofocus ■ Various imaging modes *For more details, please download the PDF or feel free to contact us.

• Other Analysis
• Cell Analysis Software

The "CytoSMART Lux2 (Smart Live Cell Imaging Device)" is a compact inverted microscope for brightfield time-lapse imaging. It operates within a standard CO2 incubator and can be utilized for cell culture processes. You can monitor it remotely from your smartphone, tablet, or computer. 【Features】 ■ Monitor cell culture throughout the day ■ Stable incubator environment ■ Remote monitoring ■ Email alert notifications ■ Easy setup and access *For more details, please download the PDF or feel free to contact us.

• Other Analysis
• Culture Equipment
• Culture vessel

The "CytoSMART Multi Lux2 (Live Cell Imaging System)" operates 2 to 4 devices with a single computer, saving valuable lab space. It allows for real-time observation of cell proliferation progress in different specimens under the same conditions, completely non-invasively. 【Features】 ■ Simultaneous observation of multiple specimens ■ Continuous monitoring of cell culture throughout the day ■ Stable incubator environment ■ Remote monitoring ■ Email alert notifications ■ Easy setup and access *For more details, please download the PDF (English version) or feel free to contact us.

• Other Analysis
• Culture Equipment
• Culture vessel

We handle the microbial cell counter 'QUANTOM Tx(TM)' manufactured by Logos Biosystems. The 'QUANTOM Tx(TM)' automatically identifies individual bacterial cells and can count the number of cells in just a few minutes. It measures fluorescently stained microbial cells, achieving accurate and objective counting of bacterial cell numbers. [Innovation] - Uniform distribution and fixation - QUANTOM Tx(TM) cell loading buffer - QUANTOM Tx(TM) centrifuge - Bacteria-specific non-clustering algorithm *For more details, please download the PDF or feel free to contact us.

• Cell Counter
• Microbiology

The "LUNA-FX7" is an automatic fluorescent cell counter equipped with quality control features and precise verification slides for QC and production monitoring. In addition to ease of use, it contributes to improving accuracy, throughput, and enhancing your workflow and security through software upgrades. 【Features】 ■ Unmatched cell counting accuracy ■ Optimized applications for bioprocess production ■ Compliant with 21CFR Part 11 FDA regulations *For more details, please download the PDF or feel free to contact us.

• Cell Counter

"LUNA(TM)" is an automatic cell counter that can provide accurate live/dead cell count results within 7 seconds. The "LUNA(TM) software" can accurately distinguish between live cells, dead cells, and debris for cells with a concentration range of 5×10^4 to 1×10^7 cells/mL and a diameter range of 3 to 60 μm. 【Features】 ■ Extremely cost-effective ■ Convenience: Achieves the highest level of cell measurement accuracy *For more details, please download the PDF or feel free to contact us.

• Cell Counter

The "LUNA II(TM)" is a standalone automatic cell counter that integrates a precision microscope optical system, computer, image analysis software, autofocus system, and built-in printer. It can accurately detect all cells, live cells, and dead cells within a cell concentration range of 5×10^4 to 1×10^7 cells/mL and cell sizes from 3 to 60 μm. It demonstrates top-class cost performance in the automatic cell counter market. 【Features】 ■ Fully automated cell counting and viability counting ■ High-speed, high-reliability cell counting with autofocus technology ■ Counting for both stained and unstained cells ■ Compatible with a wide range of cell sizes ■ High-speed, high-precision counting ■ Built-in computer and printer *For more details, please download the PDF or feel free to contact us.

• Cell Counter

We handle the two-wavelength fluorescent automatic cell counter 'LUNA-FL(TM)' manufactured by Logos Biosystems. The 'LUNA-FL(TM)' offers unparalleled counting speed and accuracy for various types of cells, thanks to its advanced integrated fluorescent optical system. It features an interactive touchscreen interface that enables precise cell counting. 【Features】 ■ High-sensitivity cell counting with a two-wavelength fluorescent optical system ■ Compatible with primary cultured cells such as PBMCs, spleen cells, neutrophils, and stem cells ■ Unmatched cell counting accuracy ■ Fluorescent and bright field optical systems ■ Exceptional cost-effectiveness for cell counting environments *For more details, please download the PDF or feel free to contact us.

• Cell Counter

We offer the two-wavelength fluorescent automatic cell counter 'LUNA STEM(TM)' manufactured by Logos Biosystems. The 'LUNA STEM(TM)' can accurately count both nucleated and non-nucleated cells simultaneously, thanks to its advanced fluorescent optical system and analysis software. 【Features】 ■ Advancement: Two-wavelength fluorescent optical system ■ Speed - Recording in 3 channels: Image generation in 30 to 60 seconds ■ Accuracy: Distinguishes between nucleated and non-nucleated cells ■ Convenience: User-friendly software with simple counting procedures *For more details, please download the PDF or feel free to contact us.

• Cell Counter

"LumiScope" enables in vivo observation and brightness measurement of neuronal activity in deep brain regions and changes at the single-cell level in vivo, which could not be observed with optical microscopes. With a diameter of 350μm, the ultra-fine optical lens and an array of 10,000 imaging fibers achieve a spatial resolution of 2μm. This allows for experiments using various fluorescent proteins and fluorescent calcium indicators, as well as the control of specific neuronal activity through light stimulation of optogenetic proteins such as ChR2 and NpHR. 【Features】 ■ Low-invasive calcium imaging in deep brain regions ■ Measurement in a free-moving environment ■ Compatible with various fluorescent proteins and probes ■ Label-free neuronal activity imaging through endogenous fluorescence measurement ■ Measurement of blood flow in capillaries, etc. *For more details, please download the PDF or feel free to contact us.

• Microscope