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SPT Labtech Japan

EstablishmentMay 25, 2020
addressTokyo/Ota-ku/527 TRC Center Building, 6-1-1 Heiwajima
phone03-6423-1644
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last updated:Jun 20, 2025
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Genomics Genomics
Protein structure analysis Protein structure analysis
Drug discovery research Drug discovery research
Sample management Sample management
96/384 channel small-sized dispenser pipetter apricot 96/384 channel small-sized dispenser pipetter apricot
Sample tube vial management BioMicroLab (BML) Sample tube vial management BioMicroLab (BML)
Micro dispensing machine, micro dispensing device, dragonfly, mosquito Micro dispensing machine, micro dispensing device, dragonfly, mosquito
Protein grid preparation for cryo-electron microscopy (Cryo-EM) Protein grid preparation for cryo-electron microscopy (Cryo-EM)
Protein

Protein grid preparation for cryo-electron microscopy (Cryo-EM)

We introduce the next-generation protein sample grid adjustment device, Chameleon, and the grid HexAuFoil for Cryo-EM.

Automated grid freezing system for Cryo-EM chameleon

For high-quality, reproducible CryoEM grid preparation!

We assist in the creation of high-quality Cryo-EM samples. Thanks to the nanowires on the grid surface, blotting of the samples is unnecessary. ● High-speed sample processing without blotting Using hygroscopic grids treated with nanowires allows for rapid sample dispensing in the air. This reduces the effects of the gas-liquid interface and may address issues related to preferred orientation, aggregation, or denaturation. ● Automated grid processing A series of operations from sample application to freezing of the grid set in the grid holder is automated. The movements are precisely controlled, preventing manual damage or loss. ● Sample tracking and recording To ensure reproducibility, relevant parameters and grid images are recorded. ● Features ◻︎ Glow discharge device integrated into the workflow inside the main unit ◻︎ Function to adjust the drop speed of the tweezers ◻︎ QC system after sample dispensing ◻︎ Data tracking and reporting capabilities

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Grid for CyroEM HexAuFoil

A revolutionary gold grid enables stable imaging! With a high-density hexagonal design and ultra-small holes, it supports the generation of uniformly thick ice.

HexAuFoil samples support improves every image! CryoEM inherently has issues with data loss caused by particle movement during imaging, which leads to a decrease in mapping quality. While data processing can mitigate this data loss, advanced sample processing techniques are required. To address these issues, we propose a solution using the new cryoEM grid "HexAuFoil," which has been launched by Quantifoil, a group company of SPT Labtech.

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