SPT Labtech Japan List of Products and Services

We assist in the creation of high-quality Cryo-EM samples. Thanks to the nanowires on the grid surface, blotting of the samples is unnecessary. ● High-speed sample processing without blotting Using hygroscopic grids treated with nanowires allows for rapid sample dispensing in the air. This reduces the effects of the gas-liquid interface and may address issues related to preferred orientation, aggregation, or denaturation. ● Automated grid processing A series of operations from sample application to freezing of the grid set in the grid holder is automated. The movements are precisely controlled, preventing manual damage or loss. ● Sample tracking and recording To ensure reproducibility, relevant parameters and grid images are recorded. ● Features ◻︎ Glow discharge device integrated into the workflow inside the main unit ◻︎ Function to adjust the drop speed of the tweezers ◻︎ QC system after sample dispensing ◻︎ Data tracking and reporting capabilities

HexAuFoil samples support improves every image! CryoEM inherently has issues with data loss caused by particle movement during imaging, which leads to a decrease in mapping quality. While data processing can mitigate this data loss, advanced sample processing techniques are required. To address these issues, we propose a solution using the new cryoEM grid "HexAuFoil," which has been launched by Quantifoil, a group company of SPT Labtech.