日本薬業　原料事業部 Product Lineup

GrantriaⓇ is an inner beauty ingredient that combines three effective components (ellagic acid, punicalagin, and punicic acid) found in pomegranate in a unique ratio to promote beauty. Utilizing Zeus Hygia's proprietary ADOP Technology, we have successfully encapsulated the pomegranate seed oil and water-soluble extract in their entirety, allowing for the simultaneous incorporation of three components that combat oxidative stress. In a study involving 80 women aged 35 to 65, those who took 300 mg of GrantriaⓇ daily for 60 days showed significant improvements in crow's feet, forehead wrinkles, skin luster, and roughness compared to the placebo group. (Am J Transl Res. 16, 8043, 2024) We propose a new beauty routine of consuming GrantriaⓇ for spot and wrinkle care in addition to daily skincare. [Announcement] We will be participating in the Food Development Expo held at Tokyo Big Sight West Halls 1, 2, and 4 & Atrium on October 14 (Wednesday), 15 (Thursday), and 16 (Friday), 2026! Details will be updated as they become available. We look forward to seeing you there!

• others

Mango is known as a delicious fruit with high nutritional value, but its parts such as seeds, leaves, and bark have traditionally been used for health purposes since ancient times. The active component mangiferin found in mango leaves and bark is known for its antioxidant, anti-inflammatory, and immune-modulating effects (Pharmacogn Rev. 4, 42, 2010). StadiceⓇ has successfully stabilized mangiferin contained in mango bark extract using Insolib technology, a proprietary technology of Zeus Hygia. Its neuroprotective effects through the antioxidant power of mangiferin contribute to maintaining brain health. In a human trial involving 60 healthy participants aged 18 to 45 who engage in e-sports, StadiceⓇ was administered at a dosage of 300 mg/day for 7 consecutive days, and various tests were conducted to measure cognitive abilities. Significant improvements were observed in mental speed, concentration, mental attention, and response inhibition compared to before intake (Cureus 16, e65751, 2024). 【Announcement】 We will participate in the Food Development Expo held at Tokyo Big Sight from October 14 to 16, 2026! We look forward to seeing you there.

• others

Turmeric (known as "ukon" in Japanese) is recognized as a spice for curry, but it has also been widely used in traditional medicine as a gastrointestinal remedy. Its active component, curcumin (curcuminoids), has antioxidant and anti-inflammatory properties, and curcumin is well-known for its functions in protecting the liver and improving fatigue, as well as various other effects such as maintaining cognitive function (Nutrients 2020, 12, 1678) and reducing discomfort in the knee joints (J Orthop Sci (2014) 19:933–939) have been reported (Chem Biol Interact, 174, 27, 2008; Carcinogenesis, 25, 1671, 2004). Biosolve CurcuminⓇ, developed by Zeus Hygia, utilizes a unique encapsulation technology called Biosolve Technology to encapsulate curcumin. This material enhances the water dispersibility, absorption, and bioavailability of curcumin. Compared to regular curcumin, it is expected to improve the antioxidant and anti-inflammatory effects of curcumin, and human trials have confirmed its efficacy in reducing joint pain.

• others

We have successfully manufactured the traditional Chinese food "Dou Chi" using our unique fermentation technology and extracted the beneficial component "Dou Chi Extract," which gently regulates blood sugar levels. We are maximizing the functions hidden in this traditional food, which has been passed down since ancient times, through the power of science. It can be applied to various products such as supplements in capsule or tablet form, cookies, rice crackers, instant miso soup, and other foods. We use organic certified soybeans and HALAL certified ingredients. This long-selling product has also received positive feedback overseas. For more details, please feel free to contact us.

• Food/beverage functional materials

The male menopause syndrome (LOH syndrome) is known to cause various symptoms due to a decrease in testosterone secretion, with an estimated number of patients in Japan being around 6.55 million. Japan Pharmaceutical Industry has been conducting research on the development of materials to support men dealing with testosterone reduction issues and has launched the patented material "Steron Power Mix." This is a powdered blend of plant extracts that can be applied to various products, including supplements for middle-aged men and those in the fertility generation. For further details, please feel free to contact us.

• Food/beverage functional materials

Black tea is one of the classifications of Chinese tea, characterized by microbial fermentation. "Black Tea Extract Powder" is a proprietary ingredient developed based on traditional methods. Its effectiveness has been confirmed in human trials, and it has a track record of functional food notifications, with support for notifications available. It is a powder made from 100% plant extracts without the use of excipients. HALAL certified ingredient. For more details, please feel free to contact us.

• Food ingredients (powder)

We discovered "Katsuobushi Oligopeptide," which gently promotes the rise in blood pressure through a unique method derived from the traditional Japanese ingredient katsuobushi, and have commercialized it. We have standardized its angiotensin-converting enzyme inhibitory activity. It can be applied to various products such as supplements in capsule or tablet form, cookies, rice crackers, instant miso soup, and other foods, as well as stick jelly and drinks. It is a long-selling product that has received positive feedback overseas. For more details, please feel free to contact us.

• Food ingredients (powder)