テカンジャパン List of Products and Services

Proven performance in a wide variety of applications. A reliable production system compliant with ISO13485. Sturdy design with a two-year free warranty. It is also possible to discharge small amounts of liquid with high speed and precision under high pressure. Equipped with a pressure sensor that detects blockages in liquid nozzles. The robust design and maintenance-free operation also reduce service costs for embedded devices, contributing to a lower failure rate of the equipment. The movement of valves and pistons can be easily controlled via commands. Report functions and error logs are also automatically sent. *For more details, please download the PDF or contact us.

• Other pumps

0.7 seconds of high-speed dispensing. No calibration required. Extremely low backlash. The reproducibility of dispensing 2μl with a 500μl piston is in the CV 0.3% range. Would you like to design this pump in 3D? No registration required, anyone can access it. https://apps.kaonadn.net/5463001/pulssar/index.html#;7 1) Material of the piston 2) Material of the piston manifold 3) Type of valve and material used 4) Presence of control board 5) Presence of pressure sensor 6) Position of ports 7) Position of mounting brackets 8) Shape of the cables used Please select from the above. When requesting a quote, please send the data from the "Bill of Materials" tab to the representative of Tekan Japan Co., Ltd. *For more details, please download the PDF or contact us.

• Other pumps

- Long-term maintenance-free: No regular replacement parts. Durability of 15 million cycles. Options for materials resistant to strong liquids. - One stroke takes only 0.4 seconds (depending on piston size). - Short development time: Complies with ISO 13485, 9001, FDA 21 CFR Part 820 requirements, UL approved, compliant with RoHS and REACH regulations for in vitro diagnostic analysis devices and pre-treatment equipment. Components that do not require validation. - Easily control delicate liquid movements with command control only. - Compact: Width 4 cm, Depth 12 cm, Height 12 cm. *For more details, please download the PDF or contact us.

• dispenser

High-precision components that bring maintenance-free operation for long periods, short development times, low cost, and compactness to in vitro diagnostic analyzers and POCT analyzers. *For detailed specifications, please click "Download Catalog" below.* - Improved accuracy and reduced tact time through backlash compensation mechanism. - Maintenance-free for long periods: No regular replacement parts. Durability of 5 million cycles. Options for materials resistant to strong liquids. - Less than CV 0.05% at full stroke, similar high precision even with piston micro-movements. - Short development time: Quick optimization through base options. Meets ISO 13485, FDA 21 CFR Part 820 requirements, UL approval, RoHS compliance, and REACH compliance. - No need for validation or calibration (backlash compensation structure). - Option to choose whether to include a control board. (Control board: Easily controls subtle liquid movements via commands. Diverse error logs are also automatically generated.) - Low cost. - Short lead times even as of 2022. - Pressure sensor: Detects liquid leakage as small as 1μl. - Compact and lightweight. *For more details, please download the PDF or contact us.*

• X-ray fluorescence analyzer
• Syringe Pump
• Analytical Equipment and Devices

An example of compound management automation using Tecan's innovative liquid handling platform, Fluent.

• Automatic Dispensing Device

An example of compound management automation using Tecan's innovative liquid handling platform, Fluent.

• Other cell research

Fluent achieves greater capacity and faster speeds. This platform offers excellent throughput and walkaway time, making it easier and more effective to conduct experiments. Tecan and Fraunhofer IME ScreeningPort have developed a protocol to demonstrate the capabilities of the Fluent laboratory automation solution for biochemical assays by combining their expertise in automated liquid handling. It has become possible to provide high-speed, reliable, and fully automated assays without the need for specialized automation personnel.

• Other cell research

Cisbio EPIgeneous cell-based assays allow for the direct measurement of methylation, demethylation, and total protein in both adherent and suspended cells. Tecan has achieved automation using the Fluent dispensing system, which is built based on the specific needs of lab applications. Fluent provides greater capacity and speed. This platform offers excellent throughput and walkaway time, enabling more reliable results and making it easier to perform many experimental processes. Tecan, in combination with Cisbio, known for its HTRF technology, has developed new protocols by combining expertise in automated liquid handling, detection, and cell-based assays. This enables the execution of fast, reliable, and fully automated assays.

• Other cell research

The NCI-60 panel is a collection of various cancer cell lines and is one of the most important tools in drug discovery for evaluating the activity of anticancer agents. While cell lines are commonly used in molecular biological assays, when combined with bioinformatics such as the NCI COMPARE database, results obtained from the NCI-60 panel can also estimate the mechanisms of drug efficacy against novel compounds. The efficacy evaluation for a large variety of compounds is initially tested at a single concentration. Hit compounds that show cell growth inhibition or cytotoxicity are then profiled in detail against multiple cell lines by creating dilution series. Tekan and the German biotech company European ScreeningPort GmbH have developed a protocol to demonstrate this cell-based assay solution. By combining expertise in cell-based assays from automated liquid dispensing to detection, they provide fast and reliable fully automated assays. After sample preparation using Fluent, cell viability was measured using luciferase detection for cellular ATP measurement (CellTiter-Glo, Promega).

• Other cell research

Performing G protein-coupled receptor (GPCR) assays using live cells in a high-throughput manner is an important part of the drug discovery process for small molecules. By combining the Fluent laboratory automation solution designed for live cell assays with the DiscoveRx PathHunter β-Arrestin human and ortholog GPCR assay kits, 384-well plate-based assays can be executed in high throughput. This platform offers excellent throughput and walkaway time, making it easier to run more applications. It is recommended for pharmaceutical researchers and CRO researchers who want to enhance the throughput of GPCR assays.

• Other cell research

Proven performance in a wide variety of applications. Rugged design reduces service costs for embedded devices. Contributes to a decrease in device failure rates. High resolution: 6000 or 48,000 steps. No calibration required. A hit product used in large quantities worldwide.

• dispenser
• Syringe Pump
• Positive Displacement Pump

＝＝＝＝＝ Summary ＝＝＝＝＝ The Tekan Cavro XCalibur is a compact and lightweight OEM syringe pump with high dispensing accuracy. In recent years, the Excalibur has been applied to analytical devices and clinical diagnostic equipment worldwide due to its performance and durability, and it is actively incorporated into our automatic dispensing systems. It is suitable for product development that requires space-saving and high dispensing accuracy. It is fully RoHS compliant. The valve supports various liquid path switching. The photo shows a model equipped with a specially designed valve. Additionally, a new solenoid valve type has also been released. (*Demo and pump loan (including evaluation kits) are available) *For detailed specifications, please click "Download Catalog" below.

• Other physicochemical equipment
• Analytical Equipment and Devices
• Syringe Pump

Tekan's high-precision and compact lightweight syringe type for efficient product development and cost reduction! Height is 12.7 cm (Demo available.) *For more details, please download the PDF or contact us.

• Other pumps
• Syringe Pump
• Positive Displacement Pump

Tekan's high-precision and compact lightweight syringe type for efficient product development and cost reduction! Height is 12.7 cm (Demo available). *For more details, please download the PDF or contact us.

• Other pumps
• Syringe Pump
• Positive Displacement Pump

◆Product Description The Freedom EVO75, with its compact body, can incorporate options and modules (for separation and detection, etc.) to accommodate a wide range of applications from DNA extraction to PCR setup, sample dilution, normalization, and various assay development. ◆New Features and Characteristics - A single dispensing arm can access everything from tubes and reagent vials to 384-well microplates. Dispensing volumes range from 1 µL to 1000 µL. - In addition to the Freedom Evoware software, it is also equipped with Sample Oriented EVOware (SOE). Standard tasks such as serial dilutions and creating standard curves, as well as information dispensing via worklists and sample layout mapping for assay plates, can be easily performed. - Despite its small size, it has a spacious worktable that can hold up to 320 test tubes or a maximum of 9 plates at once. It is also capable of expanding with options like the transport arm and Te-VacS, as well as accommodating third-party devices. ■For more details, please request the materials.

• Dispenser

Long-lasting New Concept Syringe Pump Now Available ＝＝＝＝＝ Overview ＝＝＝＝＝ The Centris Pump is a compact syringe pump module for OEM laboratory equipment that offers high accuracy, reliability, and reproducibility. The new Centris Pump features a simple yet robust mechanical design that requires minimal maintenance. It has the smallest footprint among OEM syringe pumps and is fully RoHS compliant. ★ For technical specifications of the Centris Pump, please download the catalog ★ ＝＝＝＝＝ Features ＝＝＝＝＝ - Utilizes long-life ceramic valves and ceramic syringes Capable of handling high liquid temperatures - High reproducibility: less than 0.05% CV/FS - High resolution: 181,490 steps - Programmable flow rate: 5 nl/s to 5 ml/s - Compact size (installation space: 69×45 mm) * For more details, please download the PDF or contact us.

• Other pumps

●96-well dedicated absorbance microplate reader ●High precision and high reproducibility ●4 filters, 6 filters (optional*) or rainbow filter (with free wavelength selection function) ●Simultaneous measurement of 12 wells and bidirectional measurement, completing 1 wavelength in 6 seconds and 2 wavelengths in 8 seconds *With rainbow filter, 1 wavelength takes 8 seconds and 2 wavelengths take 16 seconds ●High-precision temperature control from room temperature to 42°C ●12 channels for measurement and 1 channel for reference ●Compact design ●Easy integration into automation systems ●Compliant with EU IVD Directive 98/79/EC ●Fast and easy measurement and data analysis with Japanese version Magellan(TM) software ●Performance management with QC Pac tool (optional) ●Quality inspection results can be saved in the Sunrise IQOQ documentation package *For more details, please download the PDF or contact us.

• Other inspection equipment and devices

The Infinite F500 is a multi-detection mode plate reader. Production ended in 2020. The successor to the Infinite F500 is the "Spark" series. The new Spark model is a filter-based multi-mode microplate reader with even higher sensitivity, allowing for the selection of modules for different applications. It is a plate reader that utilizes a multifunctional system and the latest technology.

• Optical Measuring Instruments

**Features of Hydroflex** ◆ Dedicated to 96-well plates Compatible with various manufacturers' 96-well microplates, including flat-bottom plates, round-bottom plates, strip plates, and half-area (low-volume) plates. ◆ 8-channel/16-channel washing heads Choose between an 8-channel washing head for simultaneous washing of 8 wells (1 row) and a 16-channel washing head for simultaneous washing of 16 wells (2 rows). ◆ ELISA washing and cell washing By switching the washing program, one device can handle both ELISA washing and cell washing without the need to change the washing head. ◆ Compact design The dispensing pump and suction pump are built into the main unit, allowing for easy operation via the keypad. Up to 20 washing programs can be stored in memory. ◆ HydroControl Standard accompanying software that allows for easy programming of complex washing processes on a PC. Washing programs can also be saved on the PC. Complies with US FDA CFR 21 Part 11 (electronic records, electronic signatures). *For more details, please download the PDF or contact us.*

• Other environmental analysis equipment

System Catalog 2021 [Latest Edition] Various automation systems based on Fluent and Freedom EVO Reference prices are provided for budget applications. ◎ Automation to Enhance Productivity ● Reduction of work time ● Securing time for thinking ● Reduction of sample consumption ● Improvement of reproducibility ● Digitization of records ● Enhancement of experimental accuracy/reproducibility ● Improvement of data quality *For more details, please download the PDF or contact us.

• Analytical Equipment and Devices

The Infinite F50Plus is a state-of-the-art 8-well simultaneous measurement microplate reader. 【Features】 ◆ High-speed measurement with an 8-well simultaneous measurement absorbance plate reader ◆ Maintenance-free long-life LED lamp ◆ Compact plate reader perfectly sized for any lab ◆ Reliability proven by MTTF** benchmark values ◆ Equipped with Magellan software for multifunctional and certified data analysis ◆ Supports various applications including endpoint, kinetic, and multi-label measurements ◆ Wizard guide format, available in 9 languages including Japanese, making it easy to get started with tutorials and example files ◆ Qualitative and quantitative analysis by EIA, major calibration curve approximations, and comprehensive quality control ◆ Compliance with the European In Vitro Diagnostic (IVD) Medical Devices Directive 98/79/EC and FDA regulation 21 CFR Part 11 (electronic records and electronic signatures) through the use of Magellan Tracker software For more details, please download the PDF or contact us.

• Analytical Equipment and Devices

The Infinite 200 PRO has two single modes for absorbance and luminescence measurements, as well as four multi-modes for absorbance, luminescence, and fluorescence measurements, making a total of six configurations. It is available in a price range suitable for your needs and budget applications. *For more details, please download the PDF or contact us.

• Analytical Equipment and Devices

● Washer for 384/96 well plates (simultaneous cleaning type) ● Supports cell washing, ELISA washing, and vacuum filtration/magnetic bead washing (optional) with dedicated bracket installation ● Allows setting of dispensing speed, dispensing/suction position, and suction level according to the microplate and assay used ● Dilution washing and overflow washing ● Minimizes the liquid volume after suction by aspirating multiple locations within the well ● Equipped with Anti-Clogging function ● Liquid level detection option *For more details, please download the PDF or contact us.*

• Other cleaning machines

The Freedom EVO series is the most popular and reliable liquid handling system, with over 5,000 units installed worldwide. It is a modular platform that combines precise liquid handling and user-friendly robotic systems, providing advanced process control that researchers can easily relate to. It flexibly accommodates applications in various fields such as genomics, proteomics, and drug discovery. *For more details, please download the PDF or contact us.*

• Analytical Equipment and Devices

The Infinite M1000 PRO is a multi-detection mode plate reader. Production ended in 2020. The successor to the Infinite M1000 PRO is the "Spark" series. The new Spark model is a filter-based multi-mode microplate reader with even higher sensitivity, allowing for module selection based on applications. It is a plate reader that utilizes a multifunctional system and the latest technology.

• Optical Measuring Instruments

The Japan Agency for Marine-Earth Science and Technology (JAMSTEC) conducts extensive foundational research and development related to the ocean, including observations and predictions of the Earth's environment, studies of Earth's internal dynamics, and research on organisms in extreme environments. To support research on Earth's environmental observations, we have developed a compact observation device for measuring carbon dioxide in seawater using the Cavro® XCalibur (Excalibur) Pump from Tecan, which enables precise automatic pipetting. For more details, please contact us or download the catalog.

• Syringe Pump

Picarro, Inc. uses the Cavro(R) CentrisPump as a component of its atmospheric water vapor isotope analyzer. The company's high-sensitivity devices are designed to operate fully automatically in remote locations, providing environmental scientists with data that helps understand the Earth's climate. For more information, please contact us or download the catalog.

• Syringe Pump

HP's direct digital dispensing technology allows for non-contact dispensing of any amount directly onto assay plates, from low molecular weight DMSO solutions to biomolecules in surfactant-containing aqueous solutions, in volumes ranging from microliters to picoliters. This saves time, minimizes the consumption of valuable samples, and accelerates research. *For more details, please download the PDF or contact us.

• Dispenser

With the expansion of biobanks, there is an increasing demand for the ability to handle blood and urine samples for analysis quickly and efficiently, and to send them to downstream processing and storage stages. Tecan boasts a strong track record in the handling and preparation of biological samples for genomic research and clinical diagnostics. From this experience, we have developed workstations that can meet application-specific needs. *For more details, please download the PDF or contact us.*

• Dispenser

Automation of colony picking and media addition without contamination using disposable tips. Realization of easy and cost-effective automation of colony picking. The compact Freedom EVO75 fits into any lab space. Flexible selection of colony selection criteria, target and destination plates, types of microorganisms, and agar.

• Dispenser

Air LiHa brings unprecedented multifunctionality to the Freedom EVO platform. Since air displacement does not use system liquids, it eliminates the need for associated maintenance operations. The dispensing channels are equipped with easily replaceable inline filters, preventing contamination within the dispensing circuit. **Main Advantages of Air LiHa** - Meets customer assay requirements for dispensing quality and reliability. - Provides additional convenience by not using system liquids. - The design reduces maintenance frequency, improving system productivity and reducing costs. - Inline filters for each channel (easily replaceable by the user) prevent contamination within the dispensing circuit. - Real-time error detection, reporting, and error recovery via PMP. *For more details, please download the PDF or contact us.*

• Dispenser

Solid Phase Extraction (SPE), Liquid-Liquid Extraction (LLE), and Protein Purification - Tecan provides automation for a consistent process. ● Solid Phase Extraction (SPE) System: The solid phase extraction system caters to a wide range of fields including pharmaceuticals, forensics, food, clinical, and bioanalysis. ● Liquid-Liquid Extraction (LLE) System: The liquid-liquid extraction system supports the automation of fast, robust, and safe sample purification and quantification. ● Protein Digestion System: Automation of protein digestion to enhance peptide recovery and assay throughput. *For more details, please download the PDF or contact us.*

• Dispenser

We introduce a case study on the implementation of the Tecan Freedom EVO 200 workstation. The Life Sciences Research Laboratory at Ishihara Sangyo Co., Ltd. successfully automated efficient siRNA transfection using the Tecan Freedom EVO(R) 200 workstation through collaborative research with Osaka University’s Industry-Academia Collaboration Headquarters, paving the way for high-efficiency high-throughput screening of small RNA libraries. [Contents] - Optimization of the siRNA transfection system using HVJ envelope. - Automation eliminates variations and human errors arising from differences in experimenter skills. - Automation significantly expands the range of applications, and we are considering its use on a larger scale in the future. For more details, please contact us or download the catalog.

• Chemicals

We will introduce a case study of the Tecan Freedom EVO® workstation. At the Department of Bacteriology, Tokyo Medical University, the Freedom EVO workstation equipped with the HydroSpeed Plate Washer and the Infinite F200 PRO Multi-Detection Mode Reader is used for high-throughput screening of compounds in research on refractory bacterial infections. [Contents] - It is expected that understanding the molecular mechanisms of biofilm formation will lead to the development of effective prevention and treatment methods for biofilm infections. - The Freedom EVO is used to screen compounds that inhibit bacterial biofilm formation. - By automating processes such as dispensing compounds and culture media, plate washing, and absorbance measurement, time can be used more effectively. For more details, please contact us or download the catalog.

• Other work tools

We will introduce case studies of the Tecan Freedom EVO® liquid handling workstation. The International Drug Discovery Incubation Group at Osaka University has opened its doors to drug discovery researchers in the Kansai region, establishing a shared facility where high-throughput technologies, including the Tecan Freedom EVO workstation and the Infinite M1000 microplate reader, are available. [Contents] - The International Drug Discovery Incubation Group at Osaka University has established a shared facility with funding support from JST to assist drug discovery research at universities and companies, promoting collaborative research between academia and industry. - Equipped with the latest high-throughput devices comparable to those used in pharmaceutical companies. - Supports early-stage drug discovery research and the exploration of new target proteins, facilitating the discovery of new drug candidates. For more details, please contact us or download the catalog.

• others

We will introduce case studies of Tecan's microplate readers. Researchers at Kyoto Institute of Technology are utilizing Tecan's microplate readers and microarray devices in the development of a highly sensitive immunodiagnostic technology using immobilized single-chain antibodies (scFv). [Contents] - Leading research on a new immunodiagnostic technology that immobilizes single-chain antibodies on plastic materials - Can be produced at less than 10% of the cost compared to conventional whole antibodies (mAb), with detection sensitivity improved by 10 to 100 times - Exhibits excellent resolution even with low signal intensity - Offers high convenience for continuous measurements - Creates new scripts to enable the use of multi-well plates in different formats with just a phone call For more details, please contact us or download the catalog.

• others

We introduce a case study on the implementation of Tecan's Infinite 200 series plate reader. A research group at Nagasaki University has established a highly sensitive diagnostic method for detecting prions in cerebrospinal fluid samples from patients suspected of having Creutzfeldt-Jakob disease (CJD) using Tecan's Infinite 200 series plate reader. This raises expectations for reliable ante-mortem diagnosis. [Contents] - Researching the mechanisms of prions and their properties as infectious agents of transmissible spongiform encephalopathies (TSE) - Utilizing both monochromator-based and filter-based models of the Infinite - Recently introduced a fourth unit - Strongly wishing to use the plate reader for other research as well For more details, please contact us or download the catalog.

• others

We will introduce a case study of the Tecan FreedomEVO 75. Toa Eiyo Co., Ltd. is a pharmaceutical company engaged in the research and development of distinctive pharmaceuticals in the field of cardiovascular diseases such as angina and heart attacks. At the Fukushima Research Institute, which is responsible for the company's pharmacokinetic testing, the FreedomEVO 75 equipped with the 8 Plus 1 AccessTM dispensing arm was introduced to automate the sample pretreatment process and significantly improve work efficiency. [Contents] - They wanted to automate the sample pretreatment process to enhance work efficiency. - After processing, samples can be easily transferred to LC/MS/MS for measurement. - Even without specialized knowledge, scripts can be easily created. - By making slight modifications to existing programs, it can be applied to other operations. For more details, please contact us or download the catalog.

• Dispenser

We would like to introduce a case study on the implementation of the Tecan Freedom EVO200 workstation. The Japan Livestock Improvement Association has established a database for DNA typing related to parentage determination for pedigree registration, as well as individual identification of all cattle in Japan over the past 10 years. The association is automating DNA extraction using the Tecan Freedom EVO200 workstation equipped with a sample identification module using barcodes. [Contents] - Automation of the DNA extraction process saves manual labor and time. - Managing everything with barcodes is very convenient and eliminates human errors. - Identification using PosID barcodes is particularly important. - It also helps researchers automate tasks in other laboratories. For more details, please contact us or download the catalog.

• Dispenser

Automation of bioprocesses – Reducing costs and improving productivity. Tekan provides clear data acquisition and reliability in the scale-up process for manufacturing through the miniaturization and parallelization capabilities of its platform. It supports high-throughput process development and protein purification, as well as various downstream applications.

• Dispenser

The TouchTools PCR Wizard makes it easy to automate PCR reaction setup using the Freedom EVO PCR workstation equipped with high-performance AirLiHa (air displacement). The wizard simplifies reaction setup for a wide range of applications, from endpoint, real-time, and multiplex PCR protocols to sequencing, genotyping, gene expression, and pathogen or mutation analysis. The intuitive TouchTools interface of the PCR Wizard reduces training time in the lab and lowers costs. *For more details, please download the PDF or contact us.*

• Dispenser

We will develop and optimize an automation protocol for sample preparation for NGS based on the Freedom EVO NGS workstation. This will allow for parallel processing of many samples and improve the reproducibility of library preparation, while minimizing sample processing errors. *For more details, please download the PDF or contact us.*

• Dispenser

Comprehensive Catalog of Disposable Tips for Freedom EVO Dispensing Devices Compatible with Liquid Handling Arm (LiHa/Air LiHa) and Multi-Channel Arm (MCA96/MCA384)

• Analytical Equipment and Devices

Tecan proposes a new concept of automation in the lab through its unique system, Fluent, which is built around the needs of applications. Tecan understands the challenges faced daily in the field of cell biology research. In response to customer needs, we have developed solutions to streamline and simplify workflows.

• Automatic Dispensing Device

The "Fluent Laboratory Automation Solution" is a new lab automation system built around application needs. It features a highly adaptable workspace that can be customized freely based on the experimental content. Necessary equipment can be integrated under the deck without increasing the installation area. Equipped with an easy-to-use built-in touchscreen, the interface simplifies operation, allowing anyone to operate it intuitively. 【Features】 ■ Easy Operation: Fast and consistent operation via touchscreen ■ Safety: Active Stop & Resume function allows access to the work table even during runs ■ Improved Throughput: Dynamic Deck enables higher capacity and multidimensional access *For more details, please download the catalog or contact us.

• Analytical Equipment and Devices