Derivatization for GC/MS analysis

Proposals tailored to the purpose of analysis and the target object! GC/MS analysis of derivatized samples.

This document introduces a pretreatment method to enable the analysis of substances that are difficult to analyze using GC/MS. The pretreatment that converts difficult-to-analyze substances into analyzable substances is called "derivatization." Methods such as esterification, acylation, and silylation are used selectively according to the type and characteristics of the difficult-to-analyze substances. GC/MS measurements were conducted on citric acid solutions and citric acid solutions after esterification. It was found that citric acid, being a carboxylic acid, could not be effectively detected without derivatization, but after esterification, trimethyl citrate was detected, confirming the presence of citric acid. By performing appropriate derivatization, more accurate analysis becomes possible. [Analyzable Substances] ■ High volatility ■ High thermal stability ■ Low polarity *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices

Introducing a new device! We present an analytical method aimed at the qualitative and quantitative analysis of components contained in samples.

We have introduced the "GC-MS Gas Chromatograph Mass Spectrometer" manufactured by Shimadzu Corporation. This is one of the analytical methods aimed at qualitative and quantitative analysis of components contained in samples, used for the qualitative and quantitative analysis of volatile organic compounds such as parts, materials, residual solvents, and additives. It is necessary for the measurement target to be gasified (with a boiling point below 300°C), but it is suitable for component analysis of mixtures due to its higher sensitivity compared to IR and RAMAN, as well as the ability to separate components in the GC section. 【Overview of GC-MS Equipment】 ■ GC-MS Main Unit: GC-2030, GCMS-QP2020 NX ■ Headspace Sampler: HS-20 ■ Pyrolysis Analyzer: Multi-Shot Pyrolyzer Py-3030 ■ Specifications ・Detection Limit: Several ppm (varies depending on the measurement target) ・Headspace: 40–300°C, Sample Size 13mm x 40mm or smaller ・Pyrolysis Analyzer: 50–1050°C (EGA measurement compatible), Sample Size up to 4mm *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices
• Contract Analysis

What is the reason for this discoloration on the surface? Why are there cracks in such places? These issues will be resolved from the perspectives of electrons, atoms, molecules, and chemical reaction mechanisms!

Many defects occur during the manufacturing process of products and during their use. Among these, there are challenges related to material properties, and for those who are wondering, "It’s probably due to the material, but what should I do about it?", we propose solutions from the perspectives of electronics, atoms, molecules, and chemical reaction mechanisms. ■Examples of Challenges - What is causing this discoloration? - Why did it crack so quickly? - Why does it break immediately when subjected to a tensile test? *For more details, please refer to the PDF document or feel free to contact us.

• Processing Contract
• Other environmental analysis equipment
• others

By adding a special reagent to the sample and heating it, it becomes possible to detect substances that are usually difficult to detect!

In a typical thermal decomposition GCMS, samples are heated to detect volatile components; however, analyzing components that do not volatilize upon heating or those with low detection sensitivity is challenging. Therefore, by adding a special reagent to the sample and heating it, it becomes possible to detect substances that are usually difficult to identify. For example, in the analysis of polymers, thermal decomposition of the polymer results in the detection of a large number of decomposition products, and in some cases, peaks may overlap with other additives, making analysis difficult. However, by performing reactive thermal decomposition GCMS, it is possible to detect the methyl esters of monomers and to separate and analyze them from the additives. Thus, even when the target analytes are difficult to detect using conventional analysis, reactive thermal decomposition GCMS allows for sensitive detection by selecting appropriate reagents for the analytes. [Examples] - Analysis of phthalate esters (DIDP) - Analysis of polymers (polyethylene terephthalate) - Analysis of copper corrosion inhibitors (BTA) *For more details, please refer to the PDF document or feel free to contact us.

• Contract Analysis
• Analysis Services

For material evaluation and defect analysis! We will discuss the applied load and degradation mechanisms based on the differences in decomposition products.

Polycarbonate is a material that excels in impact resistance, weather resistance, and transparency, making it widely used in everything from industrial materials to everyday products. However, even polymers with excellent properties can undergo chemical changes, commonly referred to as degradation, due to the usage environment and the passage of time. This document presents examples of degradation analysis of polycarbonate materials subjected to UV irradiation and constant temperature and humidity testing. [Contents] ■ Thermal decomposition GC-MS analysis of polycarbonate *For more details, please refer to the PDF document or feel free to contact us.*

• Contract Analysis

Introducing the sample introduction device and the types of analytical samples and analysis content that each device specializes in!

GC-MS analysis is a method commonly used for the analysis of organic components and organic structure analysis. With auxiliary devices, it is capable of a wide range of analyses, from low molecular substances like solvents to high molecular substances like plastics. In this document, we will introduce the sample introduction devices owned by Aites, as well as the types of analysis samples and analysis content that each device specializes in. We invite you to read it. 【Contents】 ■ Overview ■ Conditions ■ Samples ■ Data Obtained ■ Analysis Examples *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices

I will introduce examples of comparing the components of color developers contained in thermal paper using solvent extraction!

As a pre-treatment for GC-MS analysis, solvent extraction can sometimes allow for highly sensitive analysis of target substances. This document introduces examples of component comparison of dirt wiped with a cloth and component comparison of color developers contained in thermal paper using solvent extraction. In addition to solvent extraction, we can propose suitable methods from various pre-treatment techniques tailored to your samples and analysis targets, so please feel free to contact us. [Contents] ■ Comparative analysis of dirt components and surrounding materials ■ Component comparison of color developers contained in thermal paper *For more details, please refer to the PDF document or feel free to contact us.

• Contract Analysis
• Contract measurement
• Other contract services

Fukuda Corporation has been pursuing leak detection for 60 years and is dedicated to advancing the future of leak testing. 【 Supporting Various Leak Tests: Air Leak Test / Gas Leak Test (Hydrogen Gas, Helium Gas) 】 We develop, manufacture, and sell leak testing equipment to inspect airtightness and sealing performance. We will propose suitable testers and devices for each inspection target. 【 Target Industries and Examples of Inspection Targets 】 - Automotive Industry: Engines, FC components, valves and piping, various parts - Electronic Components Industry: Smartphones, keyless switches, various small sensors - Pharmaceuticals / Food / Cosmetics Industry: Bottle containers, syringes, vials, eye drop containers, pillow packaging, PTP packaging We will propose the most suitable leak testers for each industry. 【 ISO Certification 】JIS Q 9001:2015 (ISO 9001:2015)

This is a collection of links to Fukuda's technical columns. It covers various topics related to leak tests and more... Please check the related links for more information.

In civil engineering sites such as mountainous areas and construction sites, it may be necessary to use wooden boards on slopes or inclined access roads. Hyper CLT boards are civil engineering materials utilizing wood CLT, which can be laid not only on flat ground but also on sloped terrain. They can be used for temporary roads, access routes, heavy machinery entry paths, and measures against muddy conditions, creating a driving environment that takes advantage of the unique surface characteristics of wood. The 5×10 board weighs approximately 230 kg, and the 5×20 board weighs about 460 kg, making them lightweight and easy to install and remove even with small machinery, which is a notable feature for maneuverability in narrow sites. This wooden board is registered as a technology under the Ministry of Land, Infrastructure, Transport and Tourism's NETIS system as "TH-250021-A," and can also be utilized for safety measures and innovative ideas in public works.

Metal cracks are one of the concerns in equipment maintenance operations. Repairs using conventional welding methods can alter the base material around the crack due to heat, leading to residual stress and deformation, which always carries the risk of "crack recurrence" or "secondary damage." Hinode Waterworks Equipment Co., Ltd.'s "Mechanical Stitching Method" is a new technique that allows for the repair of metal cracks without applying heat. By using special bolts and reinforcement plates, the crack is physically removed without affecting the base material with heat. Repairs can be performed even in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. For more details, please contact us or download the catalog.

● The production time for cast prototypes can be shortened! Since model making is not required, the production time for prototypes, which previously took about a month, can be significantly reduced. ● Model costs can be reduced! By directly producing sand molds from 3D data, there is no need for model production costs. If changes to the model are necessary, they can be addressed by modifying the 3D data. ● Similar products with different shapes and dimensions can be prototyped simultaneously! Different products, such as similar shapes or varying dimensions, can be molded at the same time in one molding process. This allows for the verification of multiple types in a short period.