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  4. Derivatization for GC/MS analysis
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  • Jan 11, 2024
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Jan 11, 2024

Derivatization for GC/MS analysis

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This article introduces a pretreatment method to enable the analysis of substances that are difficult to analyze using GC/MS. The pretreatment that converts difficult-to-analyze substances into analyzable forms is called "derivatization." Methods such as esterification, acylation, and silylation are used selectively according to the types and characteristics of the difficult-to-analyze substances. GC/MS measurements were conducted on citric acid solutions and citric acid solutions after esterification. It was found that citric acid, being a carboxylic acid, was not effectively detected without derivatization, but after esterification, trimethyl citrate was detected, confirming the presence of citric acid. By performing appropriate derivatization, more accurate analysis becomes possible.
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Derivatization for GC/MS analysis

Proposals tailored to the purpose of analysis and the target object! GC/MS analysis of derivatized samples.

This document introduces a pretreatment method to enable the analysis of substances that are difficult to analyze using GC/MS. The pretreatment that converts difficult-to-analyze substances into analyzable substances is called "derivatization." Methods such as esterification, acylation, and silylation are used selectively according to the type and characteristics of the difficult-to-analyze substances. GC/MS measurements were conducted on citric acid solutions and citric acid solutions after esterification. It was found that citric acid, being a carboxylic acid, could not be effectively detected without derivatization, but after esterification, trimethyl citrate was detected, confirming the presence of citric acid. By performing appropriate derivatization, more accurate analysis becomes possible. [Analyzable Substances] ■ High volatility ■ High thermal stability ■ Low polarity *For more details, please refer to the PDF document or feel free to contact us.

  • Analytical Equipment and Devices

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Component Analysis: GC-MS Gas Chromatography Mass Spectrometer

Introducing a new device! We present an analytical method aimed at the qualitative and quantitative analysis of components contained in samples.

We have introduced the "GC-MS Gas Chromatograph Mass Spectrometer" manufactured by Shimadzu Corporation. This is one of the analytical methods aimed at qualitative and quantitative analysis of components contained in samples, used for the qualitative and quantitative analysis of volatile organic compounds such as parts, materials, residual solvents, and additives. It is necessary for the measurement target to be gasified (with a boiling point below 300°C), but it is suitable for component analysis of mixtures due to its higher sensitivity compared to IR and RAMAN, as well as the ability to separate components in the GC section. 【Overview of GC-MS Equipment】 ■ GC-MS Main Unit: GC-2030, GCMS-QP2020 NX ■ Headspace Sampler: HS-20 ■ Pyrolysis Analyzer: Multi-Shot Pyrolyzer Py-3030 ■ Specifications ・Detection Limit: Several ppm (varies depending on the measurement target) ・Headspace: 40–300°C, Sample Size 13mm x 40mm or smaller ・Pyrolysis Analyzer: 50–1050°C (EGA measurement compatible), Sample Size up to 4mm *For more details, please refer to the PDF document or feel free to contact us.

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Attention those struggling with material properties in the manufacturing process at the Institute of Chemical Reaction Mechanisms!

What is the reason for this discoloration on the surface? Why are there cracks in such places? These issues will be resolved from the perspectives of electrons, atoms, molecules, and chemical reaction mechanisms!

Many defects occur during the manufacturing process of products and during their use. Among these, there are challenges related to material properties, and for those who are wondering, "It’s probably due to the material, but what should I do about it?", we propose solutions from the perspectives of electronics, atoms, molecules, and chemical reaction mechanisms. ■Examples of Challenges - What is causing this discoloration? - Why did it crack so quickly? - Why does it break immediately when subjected to a tensile test? *For more details, please refer to the PDF document or feel free to contact us.

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Analysis of difficult-to-detect substances by reaction thermal decomposition GC-MS.

By adding a special reagent to the sample and heating it, it becomes possible to detect substances that are usually difficult to detect!

In a typical thermal decomposition GCMS, samples are heated to detect volatile components; however, analyzing components that do not volatilize upon heating or those with low detection sensitivity is challenging. Therefore, by adding a special reagent to the sample and heating it, it becomes possible to detect substances that are usually difficult to identify. For example, in the analysis of polymers, thermal decomposition of the polymer results in the detection of a large number of decomposition products, and in some cases, peaks may overlap with other additives, making analysis difficult. However, by performing reactive thermal decomposition GCMS, it is possible to detect the methyl esters of monomers and to separate and analyze them from the additives. Thus, even when the target analytes are difficult to detect using conventional analysis, reactive thermal decomposition GCMS allows for sensitive detection by selecting appropriate reagents for the analytes. [Examples] - Analysis of phthalate esters (DIDP) - Analysis of polymers (polyethylene terephthalate) - Analysis of copper corrosion inhibitors (BTA) *For more details, please refer to the PDF document or feel free to contact us.

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[Data] Analysis of Polycarbonate Degradation by Reaction Thermal Decomposition

For material evaluation and defect analysis! We will discuss the applied load and degradation mechanisms based on the differences in decomposition products.

Polycarbonate is a material that excels in impact resistance, weather resistance, and transparency, making it widely used in everything from industrial materials to everyday products. However, even polymers with excellent properties can undergo chemical changes, commonly referred to as degradation, due to the usage environment and the passage of time. This document presents examples of degradation analysis of polycarbonate materials subjected to UV irradiation and constant temperature and humidity testing. [Contents] ■ Thermal decomposition GC-MS analysis of polycarbonate *For more details, please refer to the PDF document or feel free to contact us.*

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[Information] GC-MS Analysis Device Guide

Introducing the sample introduction device and the types of analytical samples and analysis content that each device specializes in!

GC-MS analysis is a method commonly used for the analysis of organic components and organic structure analysis. With auxiliary devices, it is capable of a wide range of analyses, from low molecular substances like solvents to high molecular substances like plastics. In this document, we will introduce the sample introduction devices owned by Aites, as well as the types of analysis samples and analysis content that each device specializes in. We invite you to read it. 【Contents】 ■ Overview ■ Conditions ■ Samples ■ Data Obtained ■ Analysis Examples *For more details, please refer to the PDF document or feel free to contact us.

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[Data] GC-MS analysis by solvent extraction

I will introduce examples of comparing the components of color developers contained in thermal paper using solvent extraction!

As a pre-treatment for GC-MS analysis, solvent extraction can sometimes allow for highly sensitive analysis of target substances. This document introduces examples of component comparison of dirt wiped with a cloth and component comparison of color developers contained in thermal paper using solvent extraction. In addition to solvent extraction, we can propose suitable methods from various pre-treatment techniques tailored to your samples and analysis targets, so please feel free to contact us. [Contents] ■ Comparative analysis of dirt components and surrounding materials ■ Component comparison of color developers contained in thermal paper *For more details, please refer to the PDF document or feel free to contact us.

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Related catalog(7)

Derivatization for GC/MS analysis

Derivatization for GC/MS analysis

OTHER
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Component Analysis: GC-MS Gas Chromatography Mass Spectrometer

Component Analysis: GC-MS Gas Chromatography Mass Spectrometer

PRODUCT
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Institute of Chemical Reaction Mechanisms

Institute of Chemical Reaction Mechanisms

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Analysis of difficult-to-detect substances using reaction thermal decomposition GC-MS.

Analysis of difficult-to-detect substances using reaction thermal decomposition GC-MS.

TECHNICAL
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[Data] Degradation Analysis of Polycarbonate by Reaction Thermal Decomposition

[Data] Degradation Analysis of Polycarbonate by Reaction Thermal Decomposition

TECHNICAL
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[Information] GC-MS Analysis Device Guide

[Information] GC-MS Analysis Device Guide

TECHNICAL
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[Data] GC-MS analysis by solvent extraction

[Data] GC-MS analysis by solvent extraction

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Hyper CLT flooring panel

Added a glossary to the website to make technical terms easier to understand.

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We have added a new **"Glossary"** to the Hyper CLT sheet website. In the civil engineering and construction industries, there are many specialized terms such as "CLT," "NETIS," "temporary roads," and "wooden lightweight sheets." Therefore, we have introduced related terms in an easy-to-understand manner so that those who are encountering Hyper CLT sheets for the first time can understand the products and technologies. Hyper CLT sheets are wooden lightweight sheets for civil engineering that utilize wood CLT and are registered under the Ministry of Land, Infrastructure, Transport and Tourism's NETIS technology as **"TH-250021-A."** We hope that by not only conveying the features of the product but also sharing the underlying technologies and terminology, users will feel a closer connection to Hyper CLT sheets. We will continue to enhance our website and provide clear information related to wood, NETIS, civil engineering, and CLT.

Oct 10, 2026

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CCS3 product photo

The new product "Vehicle Count Sensor CCS3" enables efficient occupancy management of large parking lots.

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Hotron Inc. has launched its new product, the "Vehicle Count Sensor CCS3"! This product is a ceiling-mounted sensor that combines infrared and radar technology. It reliably detects vehicles in both directions with a single unit, accommodating traffic during congestion and vehicle passing, thus achieving efficient occupancy management in large parking lots. Additionally, it can be utilized for exit warning purposes in addition to vehicle counting, contributing to the safe and smooth operation of parking facilities. 'Features' - Improved detection performance against changes in road surface during rainy weather by using both infrared and radar. - Equipped with IP67 waterproof and dustproof performance, making it effective even in salt damage areas. - Various settings can be configured from a dedicated app (for Android devices), with current settings easily understandable at a glance. - The base dimensions are the same as the previous model "CCS2," allowing for smooth replacement of existing equipment. *For more details, please refer to the product information, catalog download, or contact us.*

Oct 09, 2026

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Hyper CLT flooring panel

On September 15, we issued a press release for the hyper CLT flooring.

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On September 15, 2026, we issued a press release regarding the wooden lightweight sheet "Hyper CLT Sheet." The Hyper CLT Sheet is a civil engineering sheet that utilizes CLT (Cross-Laminated Timber) stacked in an orthogonal direction. It can be used in various locations such as temporary roads, access routes, heavy machinery work yards, and material storage areas. The 5×10 version weighs approximately 230 kg, making it relatively lightweight and easy to install, remove, and relocate. Additionally, it offers environmental benefits such as reducing glare and metallic sounds typical of wood, as well as CO2 fixation. Furthermore, it can be proposed for the use of new technologies in public works as a **registered technology with the Ministry of Land, Infrastructure, Transport and Tourism "TH-250021-A."** Through this press release, we aim to expand the new wooden lightweight sheet that combines wood, NETIS, civil engineering, and CLT to more construction sites.

Oct 09, 2026

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Casting sand mold 3D printer prototype production

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● The production time for cast prototypes can be shortened! Since model making is not required, the production time for prototypes, which previously took about a month, can be significantly reduced. ● Model costs can be reduced! By directly producing sand molds from 3D data, there is no need for model production costs. If changes to the model are necessary, they can be addressed by modifying the 3D data. ● Similar products with different shapes and dimensions can be prototyped simultaneously! Different products, such as similar shapes or varying dimensions, can be molded at the same time in one molding process. This allows for the verification of multiple types in a short period.

Oct 09, 2026

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Non-contact light beam touch sensor "HA-T Series"

【Catalog now available!】Energy-saving automatic door sensors "HA-T401/HA-T520"

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The "HA-T Series" is an energy-saving automatic door sensor that opens only for those who wish to enter, whether on a busy street or in a narrow passageway. The automatic door opens simply by bringing your hand close, addressing hygiene concerns even in facilities used by a large number of people. You can choose between "Non-vision Mount Type/HA-T401" and "Non-vision Built-in Type/HA-T520" depending on the application and installation location. 【Recommended for such places!】 ☑ Entrance facing a busy corridor ☑ Presence of counters or signs near the door ☑ Buildings facing narrow passages ☑ Buildings that prioritize aesthetics ☑ Hospitals and facilities that consider hygiene ☑ Large facilities with many doors 【Features】 ● Adaptable to various door types with four detection spot settings ● Reduces unnecessary opening and closing, contributing to energy-saving by minimizing wasteful power consumption ● Equipped with a light touch function, allowing the door to open and close just by waving your hand, ensuring hygiene ● Can also be used as a wide detection range non-vision infrared sensor ◎ For more details, please download the materials or contact us.

Oct 08, 2026

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