PAT and continuous production related to Bio Online LC [Biopharmaceutical Expo]

An advanced light scattering detector enables accurate measurement of molecular weight and molecular size of molecules in solution for biochemical analysis.

Achieve excellent reproducibility and high-precision analysis! '1260 Infinity II Bio-SEC Multi-Detector System' Size exclusion chromatography (SEC) is a standard analytical method for measuring and quantifying monomers, dimers, aggregates, and potential degradation products, and is one of the common methods required for regulatory approval. With advanced light scattering detectors, accurate measurement of molecular weight and molecular size of molecules in solution is made possible, while simultaneously achieving higher sensitivity in the detection of aggregates in the analysis of biomacromolecules. 【Features】 ■ Measure molecular weight and molecular size with accuracy and high reproducibility ■ High-sensitivity detection of aggregates with a low dead volume light scattering detector ■ Accurate measurement of molecular size and molecular weight through advanced detection ■ Reduced need for data verification and re-analysis due to excellent reproducibility ■ Metal-free flow path achieves low surface activity and high salt concentration resistance *For more details, please refer to the PDF document or feel free to contact us.*

• Separation device
• Analytical Equipment and Devices

Introduction of each pharmaceutical item! In addition to the specified columns, test items and others are also included.

On our website, we introduce HPLC columns that comply with the 18th edition of the Japanese Pharmacopoeia (Notification No. 220 by the Ministry of Health, Labour and Welfare, dated June 7, 2021). We have listed pharmaceuticals such as "Actinomycin D," "Aclarubicin," "Acrinol Hydrate," and "Azathioprine" by each item. Additionally, if there are no catalog products for the corresponding structure of fillers or column sizes, we indicate "No applicable products." There is a possibility that we can propose custom columns, so please contact us if you have any requests. [Items Listed (Partial)] ■ Actinomycin D ■ Aclarubicin ■ Acrinol Hydrate ■ Azathioprine ■ Acyclovir *For more details, please refer to the related links or feel free to contact us.

• others

Used in strong anion exchange chromatography with hydrophilicity! Rapidly perform column equilibration.

The "PL-SAX for Biomolecules" is an LC column used for the analysis of biopharmaceuticals in strong anion exchange chromatography with high hydrophilicity. By combining a robust macroporous styrene-divinylbenzene similar to PLRP-S with a polyethyleneimine coating that incorporates trimethylamine groups, it allows for the use of a wide range of pH and various solvents as the mobile phase necessary for the separation of biomacromolecules. Additionally, due to its high physical stability, it is suitable for high-speed separations using high flow rates and steep gradients. 【Features】 ■ Allows the use of a wide range of pH and various solvents as the mobile phase necessary for the separation of biomacromolecules ■ Suitable for high-speed separations using high flow rates and steep gradients ■ Rapid column equilibration ■ Column cleaning with organic solvents, strong acids/strong bases, and high salt concentration solutions is also possible *For more details, please refer to the related links or feel free to contact us.

• Other consumables

Particles, membranes, and bonds are resistant under high pressure, achieving higher resolution and faster separation!

The "Agilent BioMAb" is an LC column for biopharmaceutical analysis that uses a unique resin designed for high-resolution ion exchange separation of monoclonal antibodies. It is available in particle sizes of 1.7μm, 3μm, 5μm, and 10μm, with smaller particle size columns offering higher resolution. The packing material consists of rigid spherical cross-linked polystyrene-divinylbenzene (PS/DVB) non-porous beads. 【Features】 ■ Particles grafted with a hydrophilic polymer layer that virtually eliminate non-specific binding of antibody proteins. ■ A weak cation exchange (WCX) layer that is chemically bonded to a hydrophilic polymer coating, extremely uniform and densely packed. *For more details, please refer to the PDF document or feel free to contact us.

• Other consumables

In addition to protein separation for analysis, it can also be used for LC/MS separation with ammonia-containing mobile phases!

The "Poroshell 300" is an ideal LC column for the analysis of biopharmaceuticals, designed for the rapid separation of proteins and peptides. This column, featuring unique particles, maintains sharp and efficient peak shapes even at high flow rates. With a unique particle structure that combines a porous silica surface thin phase and a hard silica core, it shortens the diffusion distance of proteins, enabling practical high-speed HPLC separations for peptides and proteins up to 500–1,000 kDa. 【Features】 ■ The Poroshell 300 column, bonded with StableBond phases (C18, C8, C3), exhibits excellent stability and sensitivity in TFA and formic acid mobile phases. ■ Usable at pH 2 to 11, it achieves unique separations and high selectivity. *For more details, please refer to the PDF document or feel free to contact us.

• Other consumables

Achieving high reproducibility and long lifespan size-based separation for biomolecules!

The "Agilent BioSEC-5" is an LC column for biopharmaceutical analysis, filled with 5μm silica particles coated with a unique neutral hydrophilic layer to maximize column efficiency and stability. The specially designed packing increases pore volume, enhancing both peak capacity and resolution. To accommodate a wide range of size exclusion analyses, pore sizes of 100Å, 150Å, 300Å, 500Å, 1000Å, and 2000Å are available. 【Features】 ■ High recovery rates for a wide range of size-based biomolecule separations ■ Superior reproducibility and column lifespan compared to common products ■ Excellent stability under high pH, high salt, and low salt conditions ■ Usable with most aqueous buffers *For more details, please refer to the PDF document or feel free to contact us.

• Other consumables

Compatible with size exclusion analysis of most peptides and proteins!

The "Agilent BioSEC-3" is an LC column for biopharmaceutical analysis that realizes innovative technology in size exclusion chromatography (SEC). It is packed with 3μm silica particles coated with a unique hydrophilic layer. This thin polymer layer is chemically bonded to pure silica, which has sufficient mechanical strength under controlled conditions, resulting in very high separation efficiency in size exclusion. 【Features】 ■ Outstanding capacity, stability, and reproducibility for size-based separation of biomolecules ■ Sharper peaks, higher resolution, and excellent protein recovery rates ■ Achieves faster and higher separation than conventional SEC (size exclusion) columns ■ Compatible with most aqueous buffers ■ Excellent stability under both high salt and low salt conditions *For more details, please refer to the PDF document or feel free to contact us.

• Other consumables

Freeze-dried high recovery glass auto-sampler vials shipped with analysis certificate!

The "Peptide Standard Sample" is an LC column for biopharmaceutical analysis that contains 10 types of hydrophilic, hydrophobic, and basic peptides with a molecular weight range of 757 to 2845 Da. It is freeze-dried in high-recovery glass auto-sampler vials and shipped with an analysis certificate. Please feel free to contact us when you need it. 【Features】 ■ 10-peptide quality control standard sample ■ Hydrophilic, hydrophobic, and basic peptides ■ Molecular weight of 757 to 2845 Da ■ Freeze-dried in high-recovery glass auto-sampler vials ■ Comes with an analysis certificate *For more details, please refer to the PDF document or feel free to contact us.

• Other consumables

Separation efficiency standard sample for testing N/N-1 separation efficiency! Comes with an analysis certificate.

The "Oligonucleotide Standard Sample" is a bio-pharmaceutical analysis LC column that is freeze-dried in high-recovery glass auto-sampler vials and shipped with an analysis certificate. It contains synthetic nucleotides of 14, 17, 20, and 21 mer, designed to test N/N-1 separation capability. The "Oligonucleotide Ladder Standard Sample" includes synthetic oligodeoxythymidines of 15, 20, 25, 30, 35, and 40 mer. By using this standard sample, you can test the selectivity and reproducibility of the column. 【Features】 ■ Separation standard sample for testing N/N-1 separation capability ■ Ladder standard sample for selectivity and reproducibility testing ■ Freeze-dried in high-recovery glass auto-sampler vials ■ Comes with an analysis certificate *For more details, please refer to the PDF document or feel free to contact us.

• Other consumables

Easily perform data analysis and report creation with dextran ladder standard samples!

The "Glycan Standard Sample" is an LC column for biopharmaceutical analysis that allows for the verification of workflow efficiency using IgG N-linked glycan standard samples. Dextrin ladder standard samples and IgG N-linked glycan standard samples are available with or without 2-AB labeling. Please feel free to contact us when you need assistance. 【Features】 ■ Easy data analysis and report generation with dextrin ladder standard samples ■ Verification of workflow efficiency with IgG N-linked glycan standard samples ■ Available with or without 2-AB labeling ■ Comes with an analysis certificate *For more details, please refer to the PDF document or feel free to contact us.

• Other consumables

No need for multiple column screenings for each CQA! Corresponds to mAb oxidized variants and drug-antibody ratios of ADCs.

"AdvanceBio HIC" is a bio-pharmaceutical analysis LC column that achieves high separation capability of natural proteins at the intact level, providing robust and reproducible results. Incorporating ZORBAX all-porous particles and unique bonding technology, it excels in hydrophobicity and selectivity, accommodating highly challenging molecules such as monoclonal antibodies (mAb), antibody-drug conjugates (ADC), and other recombinant proteins. Additionally, all filler batches are tested with NIST mAb standards. 【Features】 ■ Dramatically improved reliability of analytical results due to enhanced column lifespan ■ All columns are individually tested to ensure efficient packing ■ Shorter columns enable faster analysis while maintaining the same separation performance as traditional columns *For more details, please refer to the related links or feel free to contact us.

• Other consumables

Consistent results can be achieved! The method can be reliably transferred even across different departments or business locations.

"AdvanceBio SEC" is an LC column for biopharmaceutical analysis that enables fast, accurate, and easy quantification of mAb aggregation and fragment analysis. This product is available in two particle sizes: 2.7μm and 1.9μm. This innovative size exclusion chromatography column, designed and developed by our company, demonstrates robust and reliable performance, achieving high-efficiency separation with high resolution. 【Features】 - High resolution and high-efficiency separation for aggregation and fragment analysis, with accurate quantification - Prevention of secondary reactions with proteins such as mAb and ADC - Reduced re-analysis due to consistent column performance - Reliable CQA analysis supported by long column life and excellent productivity *For more details, please refer to the related links or feel free to contact us.

• Other consumables

Publication of test items such as 'purity test (6) carbon monoxide' and 'quantitative method'!

This is an introduction to the target GC columns in accordance with the 18th revision of the Japanese Pharmacopoeia (Ministry of Health, Labour and Welfare Notification No. 220, June 7, 2021). It includes items such as "nitrous oxide" and "acethexamide" under "Pharmaceutical Articles," as well as "part numbers" and "specified columns." You can view detailed information through the related links. We encourage you to read it. 【Listed Items (Partial)】 ■ Pharmaceutical Articles ■ Test Items ■ Part Numbers ■ Names *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices

We will be exhibiting from Wednesday, October 1 to Friday, October 3, 2025. Makuhari Messe https://www.jagri-global.jp/hub/ja-jp/visit/feature-t/plant.html Please stop by!

To construction and civil engineering companies looking for the "next" step in digitalization. This seminar will explain the currently trending topic of "AI utilization" in 45 minutes. We will clearly introduce the latest trends, specific case studies, and steps for implementation to address questions such as "What can AI do?" and "How can it be applied to our business?" Whether your company is already advancing in DX or is just starting to consider AI, you will find hints for improving operational efficiency. 【Schedule】 1: Company introduction and instructor introduction 2: Case studies of AI utilization in the construction and civil engineering industry 3: Convincing examples! Patterns of AI utilization in construction operations 4: Three steps to avoid failure in AI implementation 5: Q&A and closing remarks

We will address the issue of young employees who, despite joining the company, leave due to reasons such as "there's no time to be taught," "I don't understand when I'm told to learn by watching," and "what is written and said varies depending on the project or person in charge." We propose a system that accumulates the know-how of veterans in AI and systems, allowing young employees to search for and solve problems on their own. 【Schedule】 1: Company introduction and instructor introduction 2: Reasons why technical inheritance is not progressing (lack of time, difficulty in verbalizing) 3: "Next-generation manual and know-how sharing methods" utilizing video and AI search 4: Examples of system construction to institutionalize technical inheritance 5: Q&A and closing remarks

We are pleased to announce that our company will be exhibiting at TECHNO-FRONTIER 2026, which will be held at Tokyo Big Sight from July 15 to 17, 2026. As an import trading company dealing with components such as transformers and DC/DC converters, we take pride in our wide range of product offerings. Each of these products is a high-quality device designed for specific applications, utilized in areas such as improving power supply efficiency and miniaturization. At our exhibition booth, you will be able to see these products in person, and we will provide detailed information about their performance and applications. We sincerely look forward to welcoming those interested in the miniaturization of power supplies.

We are pleased to announce that our company will be exhibiting at the 13th Occupational Safety and Health Exhibition, which will be held at Tokyo Big Sight from July 15 to 17, 2026. At our exhibition space, we will showcase safety products such as LED line lights, shock detection labels (Shock Watch), temperature management indicators, and industrial belt partitions. At our booth, you will have the opportunity to see these products in person and learn more about their performance and applications. We sincerely look forward to your visit.