[End] Speaker at the Cell Culture Medium Symposium hosted by Shonan I-Park.

Supporting the development of advanced therapies at every stage, from research and development to application in humans.

Features and Benefits ■ Hydrophobic, forms a monolayer on the water surface, reducing surface adsorption ■ Prevents aggregation and minimizes instability by dispersing uniformly in solution ■ Scavenges free radicals and protects against oxidative stress ■ Functions as a pH buffer and nutrient source, supporting an optimal microenvironment for sustained cell survival ■ Supports cell viability during and after freeze preservation ■ A completely non-human and non-animal derived product, reducing logistical challenges

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Maximization of cell quality characteristics, assurance of reproducible results, reduction of development time.

You can check the following Sartorius culture solutions from this catalog: ■ Stem cell culture media, supplements, and reagents ■ Immune cell culture media ■ Recombinant human albumin and biopreservation ■ Other media and reagents ■ Growth factors and cytokines ■ HEK293 media portfolio ■ Services

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For protein production using CHO cell lines.

■ A wide range of products to accelerate media development ■ Sartorius' global manufacturing network that ensures supply ■ 100% known chemical composition, animal component-free, serum-free, and free of hydrolysates with high reproducibility ■ In addition to ready-to-use catalog products, customizable and highly flexible ■ Highly filterable and soluble media and feeds

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Introducing a medium system for protein production using the CHO system!

The starter kit for the culture system "4Cell XtraCHO" includes all the necessary culture components for cell acclimatization and fed-batch culture at a 3L capacity. When progressing to larger-scale cultures, all individual culture components are available in various forms, both liquid and powder. Using production media and feed media offers benefits such as "eliminating process variability and contamination risks." 【Customer Benefits】 ■ Production Efficiency: Ideal efficiency from bench scale to manufacturing scale ■ Compliance with Regulatory Guidelines: Eliminates process variability and contamination risks ■ Reduces Process Complexity: Facilitates purification *For more details, please refer to the PDF materials or feel free to contact us.

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Next-generation chemical components known to support Vero cell proliferation and virus production.

【Features】 ■ Effective for production: Achieves high cell proliferation and virus production in media with known chemical components ■ Efficient operation: Simplifies filtration and purification in downstream processes, improving virus productivity ■ Safety and regulatory compliance: Reduces variability between processes and minimizes contamination risks

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Excellent results and flexibility with xenofree serum-free medium for lymphocyte culture!

Cell-based immunotherapy is at the forefront of cancer treatment. The most common type of cell-based immunotherapy to date is T-cell therapy (with CAR-T and TIL being the mainstream). The cells used in immunotherapy are generally cultured in a medium supplemented with human serum. The use of serum introduces variability in the process due to individual differences among donors, leading to inconsistencies in cell growth and characteristics. By removing this serum and simplifying the process, regulatory risks are reduced, and the associated logistical burdens are alleviated. Nutri-T eliminates the need for serum by replacing its essential components with specific proteins, lipids, and other small molecules. <Product Overview> ■ Xeno-free ■ Serum-free, no serum supplementation required ■ Compliant with ISO13408 ■ For research use only ■ Developed using cells from actual cancer patients ■ Excellent results with PBMC, TIL, and CAR-T ■ Outstanding results at low initial seeding density

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Xeno-free serum-free medium for hES cells and hiPS cells

NutriStem hPSC XF will be registered with the U.S. FDA Drug Master File (DMF)! NutriStem hPSC XF medium is a xeno-free (XF) medium optimized for the culture of human iPS/ES cells. It contains no animal-derived components and is composed entirely of human-derived proteins. NutriStem hPSC XF Medium has the capability to culture human pluripotent cells without the need for high concentrations of bFGF or other stimulatory growth factors or cytokines, enabling long-term culture while maintaining undifferentiated potential under both feeder-free (Matrigel coated) and on-feeder (MEF, HFF) conditions.

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Redefining the excellence of stem cells and advancing clinical applications: a complete xenofree serum-free system for the proliferation and expansion of hMSCs.

MSC NutriStem XF medium is a xeno-free medium for human mesenchymal stem cells (MSC) derived from various tissues such as bone marrow, fat, and Wharton's jelly. It supports the long-term culture of human MSC while maintaining the fibroblast-like morphology, self-renewal ability, and multipotency observed in normal MSC. MSC Attachment Solution - Xeno-free, purified human fibronectin/fibrinogen - Optimized for serum-free culture - For the proliferation and differentiation of hMSC MSC Dissociation Solution - Ready-to-use, known chemical composition - Recombinant trypsin solution NutriFreez D10 Cryopreservation Solution - Known chemical composition, animal-derived component-free, protein-free - Excellent cell adhesion and viability

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Completely serum-free xenofree medium enables advanced adipogenesis, osteogenesis, and chondrogenesis from hMSCs.

MSCgo Xeno-Free Chondrogenic Differentiation Medium is an innovative xeno-free (free of animal-derived components) and serum-free medium designed to directly induce the differentiation of human mesenchymal stem cells (hMSC) from various sources into chondrocytes. A complete medium is prepared from a basic medium and a supplement mix that includes all the growth factors and supplements necessary for differentiation. Additionally, hMSC isolated and expanded with MSC NutriStemXF can be efficiently induced to differentiate into various cell types (fat, bone, cartilage).

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A cost-effective and efficient standardized supplement designed to adhere human mesenchymal stem cells under serum-free and xeno-free culture conditions.

NutriCoat Attachment Solution is a cell adhesion substrate designed for human mesenchymal stem cells (hMSC) based on human fibrinogen, suitable for serum-free and xeno-free culture. It is optimized for human MSC derived from various tissues cultured in MSC NutriStem XF Medium. Additionally, it supports long-term culture of hMSC and the results of colony-forming unit-fibroblast (CFU-F) assays under serum-free and xeno-free culture conditions. This product is a ready-to-use solution that can be stored at room temperature, making it ideal for experiments in cell therapy research.

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Serum-free, animal-derived component-free, protein-free short-term refrigerated (2-8 °C) cell preservation solution.

The cells stored in this solution demonstrate high recovery rates, normal cell characteristics, and excellent performance due to components that provide pH buffer, osmotic support, energy substrates, and ion concentration. ■ Ready-to-use ■ Known chemical composition, free from animal-derived components, serum-free, and protein-free ■ Provides maximum safety during low-temperature storage (2 - 8°C) ■ Ensures high survival and recovery rates after low-temperature storage ■ Ensures the safety of cells during transport ■ Suppresses necrosis and apoptosis after storage ■ Ideal for a wide range of applications ■ DMF preparation in progress ■ Surpasses competitors in the market

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An all-in-one solution designed for freezing and thawing cells, with a known chemical composition, particularly for cell therapy and clinical applications.

NutriFreez D5 Salt Based Cryopreservation Solution provides an environment that can protect cells even at ultra-low temperatures (-196°C), ensuring high survival rates, recovery rates, and performance for very delicate cells. It is manufactured under current GMP conditions and demonstrates industry-leading performance. This product is optimally formulated, containing 5% DMSO, and does not include antibiotics, antifungals, hormones, growth factors, serum, or proteins.

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Powerful cryopreservation medium optimized for various cells and tissues.

NutriFreez D10 freezing preservation medium is a ready-to-use cell freezing solution that is optimized for multiple cell lines, free of animal-derived components, serum-free, and protein-free. When culturing cells in a serum-free environment, it is important to maintain serum-free conditions during cell freezing and preservation. This product has been shown to have high efficiency in cell viability, proliferation, adhesion (in relevant cell lines), and physiological activity/expression even after freezing and thawing. It has demonstrated superior results compared to serum-containing freezing media and other serum-free products, making it an ideal product for both serum-containing and serum-free applications.

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High-quality raw materials for gene cell therapy manufacturing.

■ A smooth transition from the early development stage to the clinical stage with consistent quality and performance ■ Optimal cell proliferation and differentiation ensured by excellent batch-to-batch consistency ■ Regulatory support related to GMP products manufactured in compliance with applicable GMP guidelines

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Next, making cell research and manufacturing easier.

When using cells for large-scale high-quality production, the Sartorius SoloHill microcarriers offer many advantages: ■ Proven track record: Used for over 30 years in the pharmaceutical and healthcare industries for animals and humans. ■ Streamlined solution: Ready to use immediately after sterilization, no prior hydrophilization is required. ■ Ready for immediate use: Sterilized products have a Sterility Assurance Level (SAL) of 10-6, eliminating the need for sterility validation and shortening the manufacturing process.

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Our company, the Steel Strip Company, will exhibit at the International Hydrogen Fuel Cell Expo in February 2024. We will showcase stainless steel strips for fuel cell separators.

[Speaker] Fujikei Co., Ltd. Mobility Solutions Division Chief Harunobu Okubo [Key Lecture Content] The thermal management system for EVs is being integrated with the aim of reducing weight, saving space, and cutting costs and labor. Due to fluctuations in EV demand, the market is undergoing significant transformation, requiring suppliers to offer a diverse range of products and make stringent investment decisions. Additionally, with the increase in heat generation from core components, heat dissipation materials are polarizing into high heat dissipation, high value-added products and low-cost, mass-consumption products. This seminar will introduce trends in the chaotic recent EV thermal management market from both the overall structure and key component perspectives. [Lecture Items] 1. Background and overall structure of the thermal management market 2. Market trends of core components (cooling and heating materials) 3. Market trends of heat dissipation materials 4. Market trends of battery fire-resistant insulation materials 5. Outlook and fluctuating factors of the thermal management market 6. Q&A / Business card exchange

[Speaker] Yuko Okada, President and CEO, M's Communicate Inc. [Key Lecture Content] In recent years, the renewal of point services has accelerated across various industries. The underlying trend is a significant shift where points have evolved from mere promotional measures to a strategic foundation for building relationships with customers. In this seminar, we will systematically organize the essence of this evolution based on the concept of 'Point Service 3.0'. We will explain the sources of effectiveness based on behavioral economics, the latest trends by industry, and the perspectives required in the era of engagement, while exploring the potential and direction of point services moving forward. [Lecture Items] 1. Evolution of Point Services (1.0 to 3.0) 2. Understanding the Essential Effects of Points through Behavioral Economics 3. Current Status and Strategic Choices of Common Points and Proprietary Points 4. Case Studies of Evolution in Point Services by Industry 5. The Era Where UI/UX Determines the Value of Points 6. Expansion into BtoB and BtoE and Applications for Organizational Activation 7. New Possibilities Unlocked by Future Point Services 8. Q&A / Business Card Exchange

[Speaker] Yuka Sawai, Team Leader of Biodiversity, Sustainability Consulting Office, Dentsu Inc. [Key Lecture Content] In this lecture, we will introduce the current state of biodiversity in Japan while unraveling the changing values of "coexistence with nature" that are emerging among future consumers. Through quantitative and qualitative research targeting university students, we will reveal signs that the values sought in coexistence are shifting towards "multi-well-being." We will organize the potential that nature holds for consumers and explain how a company's attitude towards "coexistence with nature" can influence its evaluation, especially now that sustainability has become the norm. Additionally, we will present five perspectives for translating the value of coexistence into a company's strengths.

Silver Son Nippon Co., Ltd. will be exhibiting at FOOMA JAPAN 2026, one of the largest food manufacturing exhibitions in the world, held in June! This year's theme for FOOMA is 'The Shift is On.' We will face the turning point in the food manufacturing industry and discover and create new value as a 'starting point for change.' We will showcase our Flash Mix, which demonstrates powerful performance even with difficult-to-handle powders, and batch mixers that are widely adopted by major food manufacturing companies. We invite you to see the actual products and experience the power of our high-shear mixers.