[End] Speaker at the Cell Culture Medium Symposium hosted by Shonan I-Park.

Supporting the development of advanced therapies at every stage, from research and development to application in humans.

Features and Benefits ■ Hydrophobic, forms a monolayer on the water surface, reducing surface adsorption ■ Prevents aggregation and minimizes instability by dispersing uniformly in solution ■ Scavenges free radicals and protects against oxidative stress ■ Functions as a pH buffer and nutrient source, supporting an optimal microenvironment for sustained cell survival ■ Supports cell viability during and after freeze preservation ■ A completely non-human and non-animal derived product, reducing logistical challenges

• others

Maximization of cell quality characteristics, assurance of reproducible results, reduction of development time.

You can check the following Sartorius culture solutions from this catalog: ■ Stem cell culture media, supplements, and reagents ■ Immune cell culture media ■ Recombinant human albumin and biopreservation ■ Other media and reagents ■ Growth factors and cytokines ■ HEK293 media portfolio ■ Services

• others

For protein production using CHO cell lines.

■ A wide range of products to accelerate media development ■ Sartorius' global manufacturing network that ensures supply ■ 100% known chemical composition, animal component-free, serum-free, and free of hydrolysates with high reproducibility ■ In addition to ready-to-use catalog products, customizable and highly flexible ■ Highly filterable and soluble media and feeds

• others

Introducing a medium system for protein production using the CHO system!

The starter kit for the culture system "4Cell XtraCHO" includes all the necessary culture components for cell acclimatization and fed-batch culture at a 3L capacity. When progressing to larger-scale cultures, all individual culture components are available in various forms, both liquid and powder. Using production media and feed media offers benefits such as "eliminating process variability and contamination risks." 【Customer Benefits】 ■ Production Efficiency: Ideal efficiency from bench scale to manufacturing scale ■ Compliance with Regulatory Guidelines: Eliminates process variability and contamination risks ■ Reduces Process Complexity: Facilitates purification *For more details, please refer to the PDF materials or feel free to contact us.

• others

Next-generation chemical components known to support Vero cell proliferation and virus production.

【Features】 ■ Effective for production: Achieves high cell proliferation and virus production in media with known chemical components ■ Efficient operation: Simplifies filtration and purification in downstream processes, improving virus productivity ■ Safety and regulatory compliance: Reduces variability between processes and minimizes contamination risks

• others

Excellent results and flexibility with xenofree serum-free medium for lymphocyte culture!

Cell-based immunotherapy is at the forefront of cancer treatment. The most common type of cell-based immunotherapy to date is T-cell therapy (with CAR-T and TIL being the mainstream). The cells used in immunotherapy are generally cultured in a medium supplemented with human serum. The use of serum introduces variability in the process due to individual differences among donors, leading to inconsistencies in cell growth and characteristics. By removing this serum and simplifying the process, regulatory risks are reduced, and the associated logistical burdens are alleviated. Nutri-T eliminates the need for serum by replacing its essential components with specific proteins, lipids, and other small molecules. <Product Overview> ■ Xeno-free ■ Serum-free, no serum supplementation required ■ Compliant with ISO13408 ■ For research use only ■ Developed using cells from actual cancer patients ■ Excellent results with PBMC, TIL, and CAR-T ■ Outstanding results at low initial seeding density

• others

Xeno-free serum-free medium for hES cells and hiPS cells

NutriStem hPSC XF will be registered with the U.S. FDA Drug Master File (DMF)! NutriStem hPSC XF medium is a xeno-free (XF) medium optimized for the culture of human iPS/ES cells. It contains no animal-derived components and is composed entirely of human-derived proteins. NutriStem hPSC XF Medium has the capability to culture human pluripotent cells without the need for high concentrations of bFGF or other stimulatory growth factors or cytokines, enabling long-term culture while maintaining undifferentiated potential under both feeder-free (Matrigel coated) and on-feeder (MEF, HFF) conditions.

• others

Redefining the excellence of stem cells and advancing clinical applications: a complete xenofree serum-free system for the proliferation and expansion of hMSCs.

MSC NutriStem XF medium is a xeno-free medium for human mesenchymal stem cells (MSC) derived from various tissues such as bone marrow, fat, and Wharton's jelly. It supports the long-term culture of human MSC while maintaining the fibroblast-like morphology, self-renewal ability, and multipotency observed in normal MSC. MSC Attachment Solution - Xeno-free, purified human fibronectin/fibrinogen - Optimized for serum-free culture - For the proliferation and differentiation of hMSC MSC Dissociation Solution - Ready-to-use, known chemical composition - Recombinant trypsin solution NutriFreez D10 Cryopreservation Solution - Known chemical composition, animal-derived component-free, protein-free - Excellent cell adhesion and viability

• others

Completely serum-free xenofree medium enables advanced adipogenesis, osteogenesis, and chondrogenesis from hMSCs.

MSCgo Xeno-Free Chondrogenic Differentiation Medium is an innovative xeno-free (free of animal-derived components) and serum-free medium designed to directly induce the differentiation of human mesenchymal stem cells (hMSC) from various sources into chondrocytes. A complete medium is prepared from a basic medium and a supplement mix that includes all the growth factors and supplements necessary for differentiation. Additionally, hMSC isolated and expanded with MSC NutriStemXF can be efficiently induced to differentiate into various cell types (fat, bone, cartilage).

• others

A cost-effective and efficient standardized supplement designed to adhere human mesenchymal stem cells under serum-free and xeno-free culture conditions.

NutriCoat Attachment Solution is a cell adhesion substrate designed for human mesenchymal stem cells (hMSC) based on human fibrinogen, suitable for serum-free and xeno-free culture. It is optimized for human MSC derived from various tissues cultured in MSC NutriStem XF Medium. Additionally, it supports long-term culture of hMSC and the results of colony-forming unit-fibroblast (CFU-F) assays under serum-free and xeno-free culture conditions. This product is a ready-to-use solution that can be stored at room temperature, making it ideal for experiments in cell therapy research.

• others

Serum-free, animal-derived component-free, protein-free short-term refrigerated (2-8 °C) cell preservation solution.

The cells stored in this solution demonstrate high recovery rates, normal cell characteristics, and excellent performance due to components that provide pH buffer, osmotic support, energy substrates, and ion concentration. ■ Ready-to-use ■ Known chemical composition, free from animal-derived components, serum-free, and protein-free ■ Provides maximum safety during low-temperature storage (2 - 8°C) ■ Ensures high survival and recovery rates after low-temperature storage ■ Ensures the safety of cells during transport ■ Suppresses necrosis and apoptosis after storage ■ Ideal for a wide range of applications ■ DMF preparation in progress ■ Surpasses competitors in the market

• others

An all-in-one solution designed for freezing and thawing cells, with a known chemical composition, particularly for cell therapy and clinical applications.

NutriFreez D5 Salt Based Cryopreservation Solution provides an environment that can protect cells even at ultra-low temperatures (-196°C), ensuring high survival rates, recovery rates, and performance for very delicate cells. It is manufactured under current GMP conditions and demonstrates industry-leading performance. This product is optimally formulated, containing 5% DMSO, and does not include antibiotics, antifungals, hormones, growth factors, serum, or proteins.

• others

Powerful cryopreservation medium optimized for various cells and tissues.

NutriFreez D10 freezing preservation medium is a ready-to-use cell freezing solution that is optimized for multiple cell lines, free of animal-derived components, serum-free, and protein-free. When culturing cells in a serum-free environment, it is important to maintain serum-free conditions during cell freezing and preservation. This product has been shown to have high efficiency in cell viability, proliferation, adhesion (in relevant cell lines), and physiological activity/expression even after freezing and thawing. It has demonstrated superior results compared to serum-containing freezing media and other serum-free products, making it an ideal product for both serum-containing and serum-free applications.

• others

Growth and transfection media suitable for various HEK cell lines.

【Features】 ▪ Completely known chemical composition ▪ No adaptation from other media or minimal adaptation work required ▪ Stable culture with seed train cultivation ▪ Robust and high performance ▪ For suspension cells ▪ This sample kit (CFV3FB4000) is for research purposes only ▪ Manufacturing use is also possible upon request

• others

Production medium optimized for gene introduction and viral infection.

【Product Features】 ▪ Uses the highest quality raw materials ▪ Known chemical composition ▪ No adaptation needed from other serum-free media, or minimal adaptation work ▪ Free from animal-derived substances, serum-free, and free from hydrolysates ▪ Manufactured in facilities compliant with ISO 9001 and ISO 13485

• others

High-quality raw materials for gene cell therapy manufacturing.

■ A smooth transition from the early development stage to the clinical stage with consistent quality and performance ■ Optimal cell proliferation and differentiation ensured by excellent batch-to-batch consistency ■ Regulatory support related to GMP products manufactured in compliance with applicable GMP guidelines

• others

Next, making cell research and manufacturing easier.

When using cells for large-scale high-quality production, the Sartorius SoloHill microcarriers offer many advantages: ■ Proven track record: Used for over 30 years in the pharmaceutical and healthcare industries for animals and humans. ■ Streamlined solution: Ready to use immediately after sterilization, no prior hydrophilization is required. ■ Ready for immediate use: Sterilized products have a Sterility Assurance Level (SAL) of 10-6, eliminating the need for sterility validation and shortening the manufacturing process.

• others

We have released an online seminar summarizing the features and usage points of our new electric curtain rail product, "Legato Como." (Viewing time: approximately 9 minutes) The release is for a limited time, so please take this opportunity to watch it. ──────────────────── ▼ What you can learn in this seminar ──────────────────── "What kind of product is Legato Como?" "How is it different from previous electric rails?" We will clearly answer these questions in the video. - A concise overview of the features and specifications of the new product - Explanation of why it can be said that "proposals are easy" - Advantages and applications of the battery-operated model that requires no wiring ────────────────────── ▼ Recommended for the following people ────────────────────── - Those who have a negative perception of electric curtain rails - Those who have seen an increase in proposals for electric products recently - Those who want to grasp the overall picture of the product first If any of these apply to you, please take a look.

On-site participation / Live streaming / Archive streaming (available for viewing multiple times over two weeks) AI agents that leverage LLM knowledge and take on specific expertise or roles are being utilized in various scenarios and gaining attention. However, a single AI agent may lack the necessary expertise and flexibility, leading to limitations in the tasks it can handle. At NTT, we are advancing research and development on multi-AI agent collaborative control, where multiple AI agents with various roles and expertise work in coordination with humans to achieve high-quality task execution and idea generation. In this presentation, we will introduce the integrated collaborative control mechanism that oversees the AI agent team while reflecting human intentions, as well as promising AI voice dialogue technology as a means of communication between humans and AI agents.

[Instructor] Mr. Toshio Kimura, Senior Consultant, Japan Management Association Consulting, Inc. [Purpose of the Event] Currently, R&D (Research and Development) in Japanese companies is at a turning point. Even in advanced R&D companies, a decline in the ratio of R&D expenses to sales is being observed. In other words, it can be succinctly stated that there is a shift towards "quality over quantity." The era of steadily increasing R&D investment is over. This means that R&D (functions and organizations) are now required to significantly enhance their value and the management results they produce compared to the past. In this seminar, we will provide a detailed explanation of the formulation and practical implementation of R&D strategies, which can be seen as a "compass" for innovating R&D (functions and organizations), including the following key points: 1. Enhancing the value and effectiveness of business and technology strategies. 2. Dramatic improvement in R&D productivity. 3. Innovation of "R&D vitality (capability + activation)," which serves as a promoting or inhibiting factor for strategies.

[Lecturer] Ken Ichimura President and CEO of Energy Pool Japan Inc. Committee Appointments as of November 2025 - Study Group on Next-Generation Decentralized Power Systems, Agency for Natural Resources and Energy - ERAB Study Group, Agency for Natural Resources and Energy - Study Group on the Nature of Simultaneous Markets, Agency for Natural Resources and Energy - Committee on Adjustment Power and Supply-Demand Balance Evaluation, Organization for Cross-Regional Operation of Power - Subcommittee on Supply-Demand Adjustment Market, Organization for Cross-Regional Operation of Power - Study Group on Future Power Supply-Demand Scenarios, Organization for Cross-Regional Operation of Power - Working Group on Future Supply-Demand Scenarios (Load Curve, DAC), Organization for Cross-Regional Operation of Power [Lecture Topics] January 26 (Monday) 1st Session: Learning About the Electricity Business and Capacity Market from Scratch 1. Fundamental Discussion: What is Power System Reform? 2. Learning About the Capacity Market from Scratch 3. Summary - Points I Would Like to Share About KW Value - 4. Q&A February 10 (Tuesday) 2nd Session: Learning About the Electricity Business and Supply-Demand Adjustment Market & Simultaneous Market from Scratch 1. Fundamental Discussion: What is Power System Reform? (Review of Session 1) 2. Learning About the Supply-Demand Adjustment Market from Scratch 3. Summary - The Future of Power Supply-Demand Adjustment Towards 2050 - 4. Q&A

[Speaker] Mr. Mamoru Narutomi, Researcher, Business and Legal System Research Department, National Institute of Information and Communications Technology [Lecture Items] 1. Introduction 2. About Dark Patterns 3. Regulations on Dark Patterns and Their Trends 4. Issues in Competition Policy and Antitrust Law 5. Conclusion 6. Q&A