[End] Speaker at the Cell Culture Medium Symposium hosted by Shonan I-Park.

Supporting the development of advanced therapies at every stage, from research and development to application in humans.

Features and Benefits ■ Hydrophobic, forms a monolayer on the water surface, reducing surface adsorption ■ Prevents aggregation and minimizes instability by dispersing uniformly in solution ■ Scavenges free radicals and protects against oxidative stress ■ Functions as a pH buffer and nutrient source, supporting an optimal microenvironment for sustained cell survival ■ Supports cell viability during and after freeze preservation ■ A completely non-human and non-animal derived product, reducing logistical challenges

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Maximization of cell quality characteristics, assurance of reproducible results, reduction of development time.

You can check the following Sartorius culture solutions from this catalog: ■ Stem cell culture media, supplements, and reagents ■ Immune cell culture media ■ Recombinant human albumin and biopreservation ■ Other media and reagents ■ Growth factors and cytokines ■ HEK293 media portfolio ■ Services

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For protein production using CHO cell lines.

■ A wide range of products to accelerate media development ■ Sartorius' global manufacturing network that ensures supply ■ 100% known chemical composition, animal component-free, serum-free, and free of hydrolysates with high reproducibility ■ In addition to ready-to-use catalog products, customizable and highly flexible ■ Highly filterable and soluble media and feeds

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Introducing a medium system for protein production using the CHO system!

The starter kit for the culture system "4Cell XtraCHO" includes all the necessary culture components for cell acclimatization and fed-batch culture at a 3L capacity. When progressing to larger-scale cultures, all individual culture components are available in various forms, both liquid and powder. Using production media and feed media offers benefits such as "eliminating process variability and contamination risks." 【Customer Benefits】 ■ Production Efficiency: Ideal efficiency from bench scale to manufacturing scale ■ Compliance with Regulatory Guidelines: Eliminates process variability and contamination risks ■ Reduces Process Complexity: Facilitates purification *For more details, please refer to the PDF materials or feel free to contact us.

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Next-generation chemical components known to support Vero cell proliferation and virus production.

【Features】 ■ Effective for production: Achieves high cell proliferation and virus production in media with known chemical components ■ Efficient operation: Simplifies filtration and purification in downstream processes, improving virus productivity ■ Safety and regulatory compliance: Reduces variability between processes and minimizes contamination risks

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Excellent results and flexibility with xenofree serum-free medium for lymphocyte culture!

Cell-based immunotherapy is at the forefront of cancer treatment. The most common type of cell-based immunotherapy to date is T-cell therapy (with CAR-T and TIL being the mainstream). The cells used in immunotherapy are generally cultured in a medium supplemented with human serum. The use of serum introduces variability in the process due to individual differences among donors, leading to inconsistencies in cell growth and characteristics. By removing this serum and simplifying the process, regulatory risks are reduced, and the associated logistical burdens are alleviated. Nutri-T eliminates the need for serum by replacing its essential components with specific proteins, lipids, and other small molecules. <Product Overview> ■ Xeno-free ■ Serum-free, no serum supplementation required ■ Compliant with ISO13408 ■ For research use only ■ Developed using cells from actual cancer patients ■ Excellent results with PBMC, TIL, and CAR-T ■ Outstanding results at low initial seeding density

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Xeno-free serum-free medium for hES cells and hiPS cells

NutriStem hPSC XF will be registered with the U.S. FDA Drug Master File (DMF)! NutriStem hPSC XF medium is a xeno-free (XF) medium optimized for the culture of human iPS/ES cells. It contains no animal-derived components and is composed entirely of human-derived proteins. NutriStem hPSC XF Medium has the capability to culture human pluripotent cells without the need for high concentrations of bFGF or other stimulatory growth factors or cytokines, enabling long-term culture while maintaining undifferentiated potential under both feeder-free (Matrigel coated) and on-feeder (MEF, HFF) conditions.

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Redefining the excellence of stem cells and advancing clinical applications: a complete xenofree serum-free system for the proliferation and expansion of hMSCs.

MSC NutriStem XF medium is a xeno-free medium for human mesenchymal stem cells (MSC) derived from various tissues such as bone marrow, fat, and Wharton's jelly. It supports the long-term culture of human MSC while maintaining the fibroblast-like morphology, self-renewal ability, and multipotency observed in normal MSC. MSC Attachment Solution - Xeno-free, purified human fibronectin/fibrinogen - Optimized for serum-free culture - For the proliferation and differentiation of hMSC MSC Dissociation Solution - Ready-to-use, known chemical composition - Recombinant trypsin solution NutriFreez D10 Cryopreservation Solution - Known chemical composition, animal-derived component-free, protein-free - Excellent cell adhesion and viability

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Completely serum-free xenofree medium enables advanced adipogenesis, osteogenesis, and chondrogenesis from hMSCs.

MSCgo Xeno-Free Chondrogenic Differentiation Medium is an innovative xeno-free (free of animal-derived components) and serum-free medium designed to directly induce the differentiation of human mesenchymal stem cells (hMSC) from various sources into chondrocytes. A complete medium is prepared from a basic medium and a supplement mix that includes all the growth factors and supplements necessary for differentiation. Additionally, hMSC isolated and expanded with MSC NutriStemXF can be efficiently induced to differentiate into various cell types (fat, bone, cartilage).

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A cost-effective and efficient standardized supplement designed to adhere human mesenchymal stem cells under serum-free and xeno-free culture conditions.

NutriCoat Attachment Solution is a cell adhesion substrate designed for human mesenchymal stem cells (hMSC) based on human fibrinogen, suitable for serum-free and xeno-free culture. It is optimized for human MSC derived from various tissues cultured in MSC NutriStem XF Medium. Additionally, it supports long-term culture of hMSC and the results of colony-forming unit-fibroblast (CFU-F) assays under serum-free and xeno-free culture conditions. This product is a ready-to-use solution that can be stored at room temperature, making it ideal for experiments in cell therapy research.

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Serum-free, animal-derived component-free, protein-free short-term refrigerated (2-8 °C) cell preservation solution.

The cells stored in this solution demonstrate high recovery rates, normal cell characteristics, and excellent performance due to components that provide pH buffer, osmotic support, energy substrates, and ion concentration. ■ Ready-to-use ■ Known chemical composition, free from animal-derived components, serum-free, and protein-free ■ Provides maximum safety during low-temperature storage (2 - 8°C) ■ Ensures high survival and recovery rates after low-temperature storage ■ Ensures the safety of cells during transport ■ Suppresses necrosis and apoptosis after storage ■ Ideal for a wide range of applications ■ DMF preparation in progress ■ Surpasses competitors in the market

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An all-in-one solution designed for freezing and thawing cells, with a known chemical composition, particularly for cell therapy and clinical applications.

NutriFreez D5 Salt Based Cryopreservation Solution provides an environment that can protect cells even at ultra-low temperatures (-196°C), ensuring high survival rates, recovery rates, and performance for very delicate cells. It is manufactured under current GMP conditions and demonstrates industry-leading performance. This product is optimally formulated, containing 5% DMSO, and does not include antibiotics, antifungals, hormones, growth factors, serum, or proteins.

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Powerful cryopreservation medium optimized for various cells and tissues.

NutriFreez D10 freezing preservation medium is a ready-to-use cell freezing solution that is optimized for multiple cell lines, free of animal-derived components, serum-free, and protein-free. When culturing cells in a serum-free environment, it is important to maintain serum-free conditions during cell freezing and preservation. This product has been shown to have high efficiency in cell viability, proliferation, adhesion (in relevant cell lines), and physiological activity/expression even after freezing and thawing. It has demonstrated superior results compared to serum-containing freezing media and other serum-free products, making it an ideal product for both serum-containing and serum-free applications.

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Growth and transfection media suitable for various HEK cell lines.

【Features】 ▪ Completely known chemical composition ▪ No adaptation from other media or minimal adaptation work required ▪ Stable culture with seed train cultivation ▪ Robust and high performance ▪ For suspension cells ▪ This sample kit (CFV3FB4000) is for research purposes only ▪ Manufacturing use is also possible upon request

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Production medium optimized for gene introduction and viral infection.

【Product Features】 ▪ Uses the highest quality raw materials ▪ Known chemical composition ▪ No adaptation needed from other serum-free media, or minimal adaptation work ▪ Free from animal-derived substances, serum-free, and free from hydrolysates ▪ Manufactured in facilities compliant with ISO 9001 and ISO 13485

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High-quality raw materials for gene cell therapy manufacturing.

■ A smooth transition from the early development stage to the clinical stage with consistent quality and performance ■ Optimal cell proliferation and differentiation ensured by excellent batch-to-batch consistency ■ Regulatory support related to GMP products manufactured in compliance with applicable GMP guidelines

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Next, making cell research and manufacturing easier.

When using cells for large-scale high-quality production, the Sartorius SoloHill microcarriers offer many advantages: ■ Proven track record: Used for over 30 years in the pharmaceutical and healthcare industries for animals and humans. ■ Streamlined solution: Ready to use immediately after sterilization, no prior hydrophilization is required. ■ Ready for immediate use: Sterilized products have a Sterility Assurance Level (SAL) of 10-6, eliminating the need for sterility validation and shortening the manufacturing process.

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We will be exhibiting at the "12th Conference of the Advanced Power Semiconductor Subcommittee" held at the Toyama International Conference Center. We will be introducing our latest analysis technology services, so please stop by! We sincerely look forward to your visit.

We will explain the thermal design of power ICs (LDO / DCDC) under the title "Thermal Design of Power ICs (LDO / DCDC)," which is crucial when designing power blocks. The explanation will cover fundamental concepts as well as delve into topics such as PCB layout and design. This webinar is recommended for those currently involved in PCB design and product development. ● Target Audience - Individuals involved in the design, technology, manufacturing, and quality control of various electrical products and power blocks - Those facing challenges or issues related to power ICs that they wish to resolve ● Title Thermal Design of Power ICs (LDO / DCDC) ● Agenda 1. Impact of IC Heat Generation - Definition of Thermal Resistance, etc. 2. Thermal Design of LDO and DCDC - How to Determine Tj 3. Losses, Heat Generation, and Thermal Shutdown of LDO 4. Losses in DCDC 5. Case Studies 6. PCB Design 7. Thermal Design Support 8. Q&A We look forward to your participation.

[Speaker] Yukio Sakaguchi, Representative, Clean Energy Research Institute [Lecture Topics] Part 1: Policy and Market Trends 　(1) Turning Point in Federal Policy 　(2) Shift to State Leadership 　(3) Changes in Power Market Structure 　(4) Transmission Constraints and Storage Demand Part 2: Technological Systems and Industrial Structure 　(1) From Lithium-Ion to Long-Duration Storage 　(2) Modularization and Scalability of BESS 　(3) Supply Chain Restructuring 　(4) Safety and Reliability Challenges Part 3: Business Models and Investment Strategies 　(1) Revenue Structure of Utility-Scale BESS 　(2) New Trends in Corporate PPAs and Distributed Storage 　(3) Structure of Private Capital Entry 　(4) Opportunities for Japanese Companies to Enter Part 4: Q&A / Business Card Exchange *The program may change based on the latest situation.

[Speaker] Shunsuke Suzuki, President and CEO, Management Techniques Co., Ltd. [Lecture Topics] 1. Introduction - Learning from the History of Success and Failure 2. How to Create a Project Concept Note - The Journey from Idea to Realization 3. Planning for Achievement - The Process from Planning to Execution 4. Selecting Engaging Talent - Defining Capability Requirements and Analyzing Talent Portfolios 5. Communication for Persuasion and Promotion 6. Exercises in Thinking Techniques using "Unique Brain Lab®": Mastering sharpened thinking by questioning "Why?" and extracting the essence.

■Date and Time: October 29, 2025 (Wednesday) 15:00-16:00 ■Format: Zoom Webinar ■Cost: Free (Pre-registration required) ■Speaker Information: Molex LLC Japan, Wataru Awazu ■Content: In this webinar, we will introduce high-efficiency, high-current connection solutions for data centers, communication infrastructure, and industrial equipment, along with Molex's latest connector products and case studies. We will clearly explain the features of high reliability, high efficiency, and compact design that meet the demands for high performance and energy savings in equipment. *Please feel free to join via the <Related Links>.