[Exhibition Information] 34th Annual Meeting of the Japanese Society of Circulatory Pharmacology

A world-class patch clamp system that is easy to operate for anyone, allowing for simple data acquisition and verification.

This is a patch clamp system of the world's smallest class that can perform gigaseal recordings, optimal for safety testing/toxicity testing/pharmacological testing/screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. 【Features】 ■ No need for manual patch clamp experience or difficult operations ■ No need for microscope, vibration table, manipulator, Faraday cage, or puller ■ 20 to 50 data points per day ■ Automation from gigaseal formation to whole cell formation ■ Compatible with voltage-dependent, ligand-dependent, and temperature-dependent channels ■ Options available for research on channel rhodopsins and mechanosensitive channels using light stimulation ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications and enables rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips ■ Optional temperature control (10 to 50°C), capable of extracellular/intracellular perfusion ■ Can be integrated with amplifiers such as HEKA and Axon *For details, please refer to the catalog available for download in PDF.

• Other physicochemical equipment
• Analytical Equipment
• Patch clamp system

A patch clamp system that incorporates a patch clamp amplifier, achieving miniaturization and reduction of installation costs, allowing for easy data acquisition and verification.

This is a world-class patch clamp system capable of performing gigaseal recordings, optimal for safety testing/toxicity testing/pharmacological testing/screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. ■ No experience with manual patch clamping or difficult operations required ■ No need for microscope/vibration isolation table/manipulator/Faraday cage/puller ■ 20 to 50 data points per day ■ Automation from gigaseal formation to whole cell formation ■ Compatible with voltage-dependent and ligand-dependent channels through pipetting ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications, enabling rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips

• Other physicochemical equipment
• Analytical Equipment
• Patch clamp system

Measurement of impedance and extracellular potential of iPS-derived cardiomyocytes.

This is a hybrid cardiotoxicity screening device capable of impedance measurement and extracellular potential measurement similar to MEA. It can detect not only cardiomyocytes but also the minute contractions of cancer cells and liver cells due to the effects of compounds. ■ Simultaneous measurement of impedance and extracellular potential ■ 96-well simultaneous measurement ■ Label-free measurement ■ Long-term monitoring capability ■ Electrical pacing & optical pacing (optional) ■ Comes with an incubation system (temperature, humidity, and CO2 control) ■ Includes multifunctional and excellent data analysis and graph creation software ■ Validated human iPS cells: iCell, iCell², AXOL CM, Cardiosight-S, MiraCell Cardiomyocytes, etc. ■ Compact desktop size: W20.5 x D18 x H11.7cm / 3.5kg (main unit)

• Other physicochemical equipment
• Other Analysis

The Langeendorff method has been transformed into the latest high-throughput technology, allowing for the measurement of contractile force in cardiomyocytes under physiological conditions similar to the natural environment of cardiac tissue.

The FLEXcyte 96, which transforms the conventional Langendorff method into the latest high-throughput technology, can measure the contractile force (mN/mm²) of cardiomyocytes for cardiotoxicity and safety evaluation, as well as drug screening, under physiological conditions similar to the native cardiac tissue environment, without missing even slight responses to cytotoxicity, regardless of whether in the chronic or acute phase, simultaneously in 96 wells. ■ Simultaneous measurement in 96 wells ■ Label-free measurement ■ Long-term monitoring possible ■ Optical pacing (optional) ■ Comes with an incubation system (temperature, humidity, CO2 control) ■ Includes multifunctional excellent data analysis and graphing software ■ Validated human iPS cells: iCell, iCell², AXOL CM, Cardiosight-S, MiraCell Cardiomyocytes, etc. ■ Compact desktop size: W20.5 x D18 x H11.7cm / 3.5kg (main unit)

• Other physicochemical equipment
• Other Analysis

Under physiological conditions, it is possible to measure the actual contractile force of iPS-derived cardiomyocytes.

Measurement of Contraction Force in Cardiomyocytes Using FLEXcyte96 The FLEXcyte membrane plate features a silicon membrane with a thickness of less than 10μm at the bottom of a 96-well plate. When cardiomyocytes are seeded onto the plate, the weight of the culture medium causes the silicon membrane to deflect, and subsequently, dynamic deflection (up and down movement) occurs due to the synchronized beating of the cardiomyocytes. By measuring the changes in deflection with our proprietary Capacitive Distance Sensor, developed in collaboration with innoVitro, it is possible to calculate mechanical stress and measure the actual contraction force under physiological conditions.

• Other physicochemical equipment
• Other Analysis

Recently, we held technical training sessions for the MilkoScan FT3 at five locations nationwide. In this training, we provided a wide range of useful information for operating the equipment, including explanations of the principles and structure of the device, how to create measurement products, daily maintenance, and how to respond to issues when they arise. Additionally, this year we introduced new methods for utilizing digital services (such as FossCalibrator and IQX) and also prepared hands-on sessions where participants could experience operating the equipment using a PC. Thank you to everyone who participated. Please feel free to contact us with any questions after the training. ------- At Foss Japan, in addition to training sessions and workshops to ensure you can use our equipment with confidence, we hold many events throughout the year. In seminars and open houses tailored to specific industries and analytical techniques, we showcase Foss's latest analytical solutions. -------

We will be exhibiting at the "Monozukuri Fair 2026" held at Marine Messe Fukuoka from October 14 (Wednesday) to 16 (Friday). We will have a working model of a "small winch" powered by an electric driver equipped with our uniquely developed self-locking reduction mechanism "shoji-lock," and we will set up a corner where you can experience the actual lifting and lowering of workpieces. Please stop by. (Hall A, Booth Number AS-57)

[Lecturers] EY Strategy and Consulting Co., Ltd. Infrastructure Advisory Partner Kenichiro Fukuda Strategy Partner Ken Fujiyama Infrastructure Advisory Director Takashi Matsumura [Key Lecture Content] The water supply and sewage business is facing structural challenges such as facility aging, a shortage of workforce, and a decrease in revenue due to population decline. The government is promoting the introduction of Water PPPs, regional consolidation, and the digital transformation of water supply and sewage systems, marking a significant turning point in the way these businesses are operated. This change is expanding business opportunities for private companies in various areas, including operation and maintenance, pipeline renewal, digital technology, and the utilization of smart meters and data. Additionally, as a means of expanding business domains and enhancing competitiveness, there has been an increase in capital and operational partnerships and M&A between companies, leading to industry restructuring. In this seminar, based on the latest trends in policy and the market, we will introduce business strategies for private companies to enter and expand in the water supply and sewage market, including the use of M&A and capital operational partnerships, drawing on achievements from both public and private support.

[Lecturer] Koichi Iwama, Professor, Faculty of Economics and Management, Wako University / Chairman, Resource Economics Committee, Petroleum Technology Association [Key Lecture Content] In light of the prolonged crisis in the Strait of Hormuz, what will happen to the development of shale gas and shale oil in the United States moving forward? After the midterm elections, what will be the international LNG prices under the Trump administration after winter 2027? How will Japan's business strategies related to LNG projects grow? A leading expert on the shale gas and shale oil revolutions will clearly explain the future outlook.

[Lecture Items] 1. Initiatives for Promoting Smart Cities at the Ministry of Land, Infrastructure, Transport and Tourism Ministry of Land, Infrastructure, Transport and Tourism, Urban Bureau, International and Digital Policy Division, Digital Information Utilization Promotion Office Planning Specialist Mr. Masahiro Kobayashi 1. Initiatives to Promote the Spread of Smart Cities 2. Promotion of the Development and Utilization of 3D Urban Models in Project PLATEAU 3. Q&A / Business Card Exchange 2. Smart Cities in the AI Era - Creating "Light Cities" that Continuously Unleash the Potential of Urban Areas - NTT Urban Solutions Inc., Urban Development Promotion Headquarters, Innovation Promotion Department, Deputy Director NTT Urban Development Corporation, Digital Innovation Promotion Department, Director Mr. Shinya Date 1. Changes in the Environment Surrounding Smart Cities and the Transformation of Urban Development 2. NTT's Vision for Creating "Light Cities" - Urban Development that Continues to Unleash the Potential of Cities 3. Evolution and Value Creation of Smart Cities in an AI-Driven Society 4. Considering Future Urban Models and Co-Creation Possibilities from Social Implementation Cases in Hibiya 5. Q&A / Business Card Exchange