We will exhibit at the DDS Society academic conference.

Accelerating formulation optimization for vaccine and pharmaceutical development.

To create the optimal LNP, it takes a tremendous amount of time and effort to examine and pursue formulation conditions. LNPs are nanoparticles composed of multiple lipids. Therefore, it is necessary to find the optimal conditions such as the mixing ratios, the ratio of lipids to payload, and the flow rates during mixing. Furthermore, we must also consider throughput issues. Sunscreen can produce up to 96 types of small LNPs within six hours, thus solving the previous throughput problems. This means that it is possible to explore a greater number of formulation condition investigations in a single day. • Fully automated execution of up to 96 types of condition investigations within six hours • 200 μL to 2 mL per experiment • Flow rate of 0.1 to 30 mL/min • Reusable microfluidic chips • Seamless scale-up through process and protocol optimization

• Other Physics and Chemistry Equipment

Efficient mass production of LNPs - Supporting everything from small-scale condition testing to scale-up.

Once we succeed in finding the optimal formulation conditions for sunscreen, let's use Sunshine to adjust the size of the LNP. Furthermore, we will optimize the protocols and processes for scaling up. We will find the ideal flow rate and explore different mixing options. Next, we will adjust these to the appropriate dilution factor that can keep them stable. Once everything is in place, Sunshine will transition to continuous mode, allowing us to produce several dozen liters in a day. In other words, we will achieve process development and scaling up on a single platform. Many researchers have likely been looking forward to the birth of such a groundbreaking system. • 10 experiments in 15 minutes • Fraction & total flow • From 1 mL to continuous flow • Flow rate 0.1 to 30 mL/min • Reusable microfluidic chips • Possible transition of protocols from sunscreen

• Other Physics and Chemistry Equipment

Accelerating formulation optimization for vaccine and pharmaceutical development.

The transition from LNP to GMP is a costly and complicated process. Typically, this requires switching equipment, using different flow paths and mixing devices, and essentially re-developing and re-validating everything that has been painstakingly done so far. With Sunbather, the transition to GMP can be done easily thanks to its recording features, interchangeable flow paths, and easily transferable design. Sunbather uses the same mixing process and protocols as the Sunscreen and Sunshine from the same Sun series, allowing for easy transition of adjusted formulation conditions to GMP. - Up to 1.8 L/h - Integrated inline dilution - Fully interchangeable flow paths - A wide variety of mixing devices - Software compliant with 21 CFR Part 11 - Process transferable from Sunshine

• Other Physics and Chemistry Equipment

Quality assessment of proteins, nucleic acids, AAV, LNP, etc. is possible with trace amounts and high throughput.

"Stunner" is a product that allows simultaneous acquisition of UV/Vis concentration, dynamic light scattering (DLS), and static light scattering (SLS) data from a 2μL identical sample. It enables detailed investigation of AAV and adenoviruses to measure total capsid titer and Empty/Full ratios, as well as to obtain payload concentration and size data of lipid nanoparticles all at once. You can analyze concentration, hydrodynamic size, polydispersity, and the presence of aggregates collectively, allowing you to assess the quality of proteins. This way, you can immediately determine whether your AAV, adenoviruses, lipid nanoparticles, or proteins are suitable for your purposes. [Features] ■ Measure up to 96 samples in a batch in 60 minutes*/12 minutes** *When measured by DLS **When measured by UV/Vis only [Applications] ■ AAV/Adenovirus capsid titer ■ AAV/Adenovirus Empty/Full ratio ■ Lipid nanoparticle (LNP) payload amount ■ Aggregate measurement ■ Concentration measurement ■ Sizing & polydispersity ■ B22 & kD *For more details, please refer to the PDF document or feel free to contact us.

• Other protein analysis

Up to 8 samples can be processed simultaneously! Automatic and hassle-free buffer exchange and concentration that used to be complicated!

Buffer exchange and concentration must be performed as a sample preprocessing step. This is a labor-intensive task that takes a long time, requiring your presence throughout the process. "UNAGI" is a fully hands-free benchtop buffer exchange solution designed to take over this tedious task. It can process up to 8 samples simultaneously. The software is very easy to operate, allowing you to be anywhere during the work, eliminating the need to stay in the laboratory the entire time. 【Features】 ■ Simultaneous processing of up to 8 samples ■ Efficient solvent removal prevents sample adsorption, achieving over 96% recovery rate ■ Built-in recipes for UF/DF buffer exchange ■ User-friendly software ■ Concentrates up to 8 diluted samples from 48mL to 8mL in one go *For more details, please refer to the PDF document or feel free to contact us.

• Other Protein Research Software
• DNA analysis

[Video Available] Are you spending a lot of time and effort on buffer exchange and concentration work? You can streamline the sample preprocessing steps with this device.

Buffer exchange and concentration must be performed as a pre-treatment of the sample, which is a time-consuming task. This process takes a long time, and you have to be present the entire time. "UNAGI" is a fully hands-free benchtop buffer exchange solution designed to perform this tedious task for you. You can be anywhere during the process, eliminating the need to stay in the laboratory the whole time. 【Features】 ■ Simultaneous processing of up to 8 samples ■ Efficient solvent removal to prevent sample adsorption, achieving over 96% recovery rate ■ Built-in recipes for UF/DF buffer exchange ■ User-friendly software ■ Concentration of up to 8 diluted samples from 48mL to 8mL in one go *For more details, please refer to the PDF document or feel free to contact us.

• Other Protein Research Software
• Other filtration and separation equipment

Introducing the details of the newly launched LNP production and screening device.

Researchers of lipid nanoparticles (LNPs) spend a tremendous amount of time on screening, optimization, and scaling up experiments to achieve optimal performance, spot-on targeting, and controlled release of active pharmaceutical ingredients (APIs). Factors such as solubility, pH stability, payload release, and encapsulation all depend on particle size, shape, and structure. In other words, to obtain the right formulation, it is necessary to explore a vast number of formulation parameters and process parameters one by one, and even if a perfect formulation is found, scaling up usually means switching equipment and re-optimizing settings. In this webinar, we will introduce a platform, Sunny Suite, that can reduce the time spent on these LNP formulations. ■ Date and Time: February 26 (Monday) 14:00~ ■ Speaker: Yuji Senoo, Field Application Scientist, Unchained Labs, Inc. ■ Register here: https://unchainedlabs.zoom.us/webinar/register/3217065146675/WN_U1o3xQoZRAKHN-A-7b1yqg

• Other protein analysis

It enables the monitoring of potency and purity throughout the entire workflow of lentivirus research and development, accelerating gene therapy development.

"Leprechaun" is a system that analyzes whether lentivirus particles are of the correct size and structure, and can measure viral titer. It allows for the determination of the titer of lentivirus present in a sample without being misled by confusing noise (such as incomplete viruses or contamination). Not only can it measure information that was previously only obtainable separately through conventional methods like ELISA, qPCR, and transduction assays, but it also enables structural analysis that those methods could not provide, all on a single platform. Capabilities: ■ Lentivirus titer ■ Lentivirus structure ■ Exosome concentration ■ Analysis of contamination (impurities such as extracellular vesicles) Features: ■ No sample purification required ■ Physical structural analysis possible ■ Distinction between virus integrity and impurities ■ Up to 16 samples can be measured at once *For more details, please refer to the PDF document or feel free to contact us.

• Other measurement and measuring equipment

Announcement of Exhibition. We will be exhibiting at the Reborn Challenge Showcase in Grand Green Osaka JAM BASE. [Exhibits] Bioplastics Sakura plates Cutlery

We are pleased to announce that our company will be exhibiting at "EdgeTech+ 2025" (held in Yokohama). <Overview of EdgeTech+ 2025> Exhibition Name: EdgeTech+ 2025 (https://www.jasa.or.jp/expo/) Dates: November 19 (Wednesday) to November 21 (Friday), 2025, 10:00 AM to 5:00 PM (until 6:00 PM on November 20, Thursday) Venue: Pacifico Yokohama Exhibition Hall / Annex Hall Organizer: Japan Embedded Systems Technology Association Admission: Free (pre-registration required) <Booth Information> Booth Number: CS-07 <Main Exhibits> - UHF Band RFID Reader/Writer Module [TPURID2100] - 920MHz Band LPWA Wireless Communication Module [TPSW9] - 2.4GHz Band Wireless Communication Module [TPBPM] - Positioning Starter Kit We understand that you may be busy, but we sincerely hope you will take this opportunity to visit us and stop by our booth.

We are pleased to announce that our company will be exhibiting at the "Industrial Exchange Exhibition 2025." <Overview of the Industrial Exchange Exhibition 2025> Exhibition Name: Industrial Exchange Exhibition 2025 (https://www.sangyo-koryuten.tokyo/) Dates: November 26 (Wednesday) to November 28 (Friday), 2025, 10:00 AM to 5:00 PM Venue: Tokyo Big Sight, West Halls 1 and 2 Admission: Free (pre-registration required) <Booth Information> Booth Number: B-04 (within the Tokyo Business Frontier Pavilion) <Main Exhibits> - UHF Band RFID Reader/Writer Module [TPURID2100] - 920MHz Band LPWA Wireless Communication Module [TPSW9] - 2.4GHz Band Wireless Communication Module [TPBPM] - Positioning Starter Kit We understand that you are busy, but we sincerely hope you will take this opportunity to visit us and stop by our booth.

100% participant satisfaction! Packed with useful information for ISMS managers! You can watch the video of the "ISMS Manager Study Session" held in Shinbashi in September 2025. The theme this time is "Latest Trends and Information Leakage Countermeasures." 【What You Can Learn】 ● The latest trends in ISMS audits and what to do before the next audit - How to efficiently run the PDCA cycle - Recent trends in audits - What to do before the next audit ● Recent trends in information leakage incidents and unauthorized access, and the information security measures to focus on now - Recent trends in information leakage incidents and unauthorized access - Key points for countermeasures based on these trends - Information security measures to focus on now 【Recommended For】 - Executives and personnel from companies that have obtained ISMS certification - Those who want to know what to prepare for the next ISMS audit - Those who want to know how to respond to recent security trends - Those who want to operate ISMS more efficiently. You can also download the materials distributed at the seminar. Please apply!

[Speaker] Taigo Isobe, Senior Manager, Innovation Center, Innovation Technology Department, NTT Data Corporation [Key Lecture Content] Quantum computers are attracting attention as a new computational mechanism based on quantum mechanics, providing innovative solutions to complex and large-scale problems that have been difficult to handle with traditional classical computers. In this lecture, I will first overview the foundational technologies and current status of quantum computers, organize the application examples that have been highlighted in the financial and chemical fields, and then outline the potential in new application areas such as odor reconstruction, weather forecasting, and digital agriculture. I hope you will realize that quantum computers are not just an extension of computational technology but are expanding into diverse areas such as perception, environment, and human sensibility.