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  3. HIGUCHI INC.
  4. We exhibited at the Interphex Week Tokyo - 9th Bio Pharmaceutical EXPO!
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  • Jul 25, 2025
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Jul 25, 2025

We exhibited at the Interphex Week Tokyo - 9th Bio Pharmaceutical EXPO!

HIGUCHI INC. HIGUCHI INC.
We exhibited at the "9th Bio Pharmaceutical EXPO" held at Tokyo Big Sight from July 9 to 11, 2025! Thank you very much to everyone who visited us. Main Exhibited Products 【Solid Dosage Form Related Products】 Mixer, Torque, Rheometer Tabletop Tablet and Granule Coating Equipment Powder Sampler IVIVC Dissolution Tester BIO-DIS III Functional additives for improving the solubility of poorly soluble drugs Pharmaceutical cleaning agents compatible with cleaning validation Granulated lactose developed for direct compression, spray-dried lactose Tablet press mortar and pestle, reducing compression time by up to 50% Functional ready-to-fill capsules galenIQ Isomalt Hydrate, and others 【Bio Pharmaceutical Related Products】 Single-use Depth Filter Single-use Mixer Bag System Single-use Assembly Bag Culture Bag SafeCell Pyrogen Test Kit (MAT Test Method) instaCELL High-precision Incubator AVATAR ODYSSEY Biomimetic System Organ-on-a-Chip, and others
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Alternative methods to animal testing: MPS (Microphysiological Systems) cell culture

A biomimetic system that tests by moving cultivated mini-organs.

Mechanical stimulation of cultured tissues such as 3D cardiac microtissues using actuators to mimic heartbeats and knee joint movements. Evaluation of changes in electrical activity after drug administration allows for in vitro safety assessment of drugs. *Measurement of heart rate, electrical activity, contractility, etc.

  • Cell culture contract service

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Alternative methods to animal testing: MPS (Microphysiological Systems) cell culture

Using neurons as bio-digital sensors. Toxicity prediction using a digital library. High-throughput device using MEA.

Microchannel technology enables compartmentalization and co-culture. Compatibility with other companies' MEAs allows for the recording of electrical activity. Determination of toxicity and efficacy through the creation of digital signatures of compounds tested on innervated target organs. Prediction of toxicity and efficacy by comparing digital signatures of compounds using a digital library.

  • Culture vessel

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Alternative methods to animal testing: Monocyte Activation Test (MAT)

Alternative methods to animal testing: Pyrogenic substance testing (compatible with endotoxin and non-endotoxin testing)

Monocyte activation test kit, an alternative method to the rabbit pyrogen test and LAL test. It uses human monocytic THP-1 cells to detect the inflammatory cytokine TNF-α. Capable of detecting gram-negative bacteria, gram-positive bacteria, fungi, and viruses.

  • Other analytical and testing equipment

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Filtration: Sterilization & Vent Capsule Filter

Sterilization applications for biopharmaceuticals and sterile preparations! Filters with high microbial retention, low protein adsorption, and extremely low elution performance.

Advanced Microdevices' sterilizing capsule filter achieves improved throughput through a pre-filter and high flow rates due to low hold-up volume. 【Features】 ■ Improved recovery rate due to low protein adsorption ■ Assurance of microbial capture performance through bacteria challenge testing ■ 100% integrity testing conducted ■ Certificate provided with each filter ■ Compatible with ethylene oxide and autoclave sterilization ■ Gamma radiation sterilization compatible

  • Other bio-related products

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Filtration: Sterilization & Vent Cartridge Filter

Various lineups are prepared based on flow rate, effective surface area, and sterilization methods.

Consistent product quality using a quality management system Establishment of product traceability through lot number management Validation support through integrity tests, extractables, leachables, adsorption, and testing Compliance with various regulations such as FDA and USP Autoclave, steam sterilization Sterilization varies by each filter For details, please contact us

  • Filtration Filter

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Cultivation: AseptiBag single-use bag for storage and transport

Reliable single-use bags required for sterile processes such as storage and transportation of media, intermediates, buffers, etc., used in biopharmaceuticals.

AsptiBag Gold uses an inactive multilayer polyethylene film that is physically robust and inert to many chemicals and solvents, while also possessing excellent gas barrier properties. The contact surface is made of 130μm ultra-low-density polyethylene without any additives. It meets various regulatory and functional requirements, providing consistently high-quality products.

  • Other bio-related products

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Cultivation: SafeCell Cell Culture Bag

FEP-made cell culture bags. Manufactured by TECHNOFLEX (France). Compliant with USP Class 6. DMF registered.

The SafeCell series is made of fluorinated ethylene propylene (FEP) and meets the demands of in vitro cell culture. FEP is chemically and biologically inert, making it perfectly suitable for cell suspension culture. Its anti-adhesion properties allow cells to freely float and proliferate in the medium. SafeCell bags are permeable to gases (oxygen, carbon dioxide, nitrogen), enabling the necessary exchanges for proper cell development, while also possessing another important characteristic: water impermeability. The low evaporation rate of SafeCell bags prevents issues even in humid incubators that increase the risk of bacterial and microbial growth.

  • Culture vessel

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Cultivation: Aseptic Sampling System

Aseptic sampling system with adapter

The disposable sampling port cartridge eliminates the need for time-consuming assembly of multi-port adapters. This allows for direct attachment to the container's port, creating a simple, fast, and immediately usable sampling system. It is a gamma-irradiated disposable system for aseptic liquid sampling at various stages of pharmaceutical and biopharmaceutical processing. These systems minimize the potential for false positives compared to traditional sampling systems and reduce the need for cleaning. A sealed system that maximizes operator safety and eliminates contamination. A simpler, faster, and completely disposable ready-to-use solution for sampling applications. There is no need for the cumbersome and time-consuming assembly of sampling system ports and multi-port adapters within the cartridge.

  • Animal cells

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Cultivation: Single-use assembly tube

To reduce contamination risks and streamline the cleaning process.

Single-use assembly tubes for biopharmaceuticals. Tube material, length, connector type, filters, etc. can be customized according to customer requirements. Manufactured in a Class 7 cleanroom. The facility is ISO 13485 and FDA certified. Compatible with gamma sterilization, with various certificates included.

  • Filtration Filter

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Filtration: Depth filter for cultivation process

No need for centrifugation‼ Cultivation filtration depth filter

The combination of deep filtration and alluvial filtration allows for the removal of CHO cells, bacteria, etc., in a single step without the need for a centrifugation step. This reduces the cost and downtime of the bioprocess.

  • Protein Extraction Kit

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Agilent Dissolution Tester BIO-DIS

Sustained-release formulation testing apparatus USP Apparatus 3

BIO-DIS is a dissolution tester for conducting release rate tests, compliant with USP Apparatus 3 and EP Reciprocating Cylinder tests. It is an ideal dissolution tester for formulations that require sustained release formulations and dissolution profiles at multiple pH levels.

  • Dissolution Tester

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HIGUCHI INC.
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Hyper CLT flooring panel

Civil CLT as common temporary works for public construction | Hyper CLT flooring

  • NEW
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In public construction civil engineering sites, there are many instances where sheets are used as common temporary facilities, such as construction roads, access roads, heavy machinery work yards, material storage areas, and worker pathways. Traditionally, steel plates were common, but due to their weight, transportation and installation can be cumbersome. Hyper CLT sheets are civil engineering materials made from wooden CLT for civil engineering use. The 5×10 sheet weighs about 230 kg, and the 5×20 sheet weighs about 460 kg, making them lightweight and easy to transport, install, and remove, even with small machinery. They can be widely utilized for temporary roads, heavy machinery scaffolding, pathways within the site, and protection of material storage in public works. Since they are made of wood, they also contribute to environmental aspects such as reducing summer heat reflection, lowering noise, and fixing CO2. They can simultaneously address construction efficiency, safety measures, and environmental considerations, making them effective for innovative proposals in public works. Furthermore, they improve transportation efficiency and reduce labor in site operations as an alternative to steel plates. Hyper CLT sheets are registered technology with the Ministry of Land, Infrastructure, Transport and Tourism under NETIS "TH-250021-A." They are recommended for companies considering civil engineering, civil engineering use, and civil engineering CLT. Feel free to request materials or consult about implementation. They are temporary materials that also help improve site evaluations in public works. Please consider them.

Jun 28, 2026

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[YouTube Update] Differences in Cleansing Ingredients You Should Know Before Developing an Original Shampoo

  • NEW
  • COMPANY

We have released a new video on our company’s YouTube channel. The theme of this video is "The World of Amino Acid-Based Shampoos." Amino acid-based shampoos have become popular in recent years, but the lather, feel, and finish can vary greatly depending on the cleansing ingredients used. In this video, we clearly explain the changes in user experience based on the differences in cleansing ingredients by comparing two types of amino acid-based shampoos. We hope you can use this as a hint for developing original shampoos and differentiation.

Jun 26, 2026

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The 2nd Japan Go IPO Summit held in Tokyo in response to the growing momentum of Japanese companies in the U.S. capital markets.

  • NEW
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New York and Tokyo, June 26, 2026 - (JCN Newswire) - This year's successful listing of PayPay Corporation (hereinafter "PayPay") on NASDAQ has provided a significant boost. The question now facing Japan's leading innovation companies is no longer "Is a U.S. listing feasible?" but rather "How can we attract global capital and build companies that align with global growth strategies?" The 2nd Japan Go IPO Summit will be held on September 16, 2026, at the Grand Hyatt Tokyo to address this question. This summit is hosted by MarcumAsia and organized by AUM Advisors. To register for this invitation-only event, please apply here: Japan GO IPO Summit Attendee Information https://events.marcumasia.com/view.php?id=32

Jun 26, 2026

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[Ministry of Economy, Trade and Industry Sponsored Seminar] "Eliminating Failures in AI Implementation" - Explanation of Successful Patterns in Manufacturing Sites with Real Examples (7/3)

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Our company representative, Shibata, will be speaking as a lecturer at the "Mikata Project" AI Utilization Seminar for the automotive industry, hosted by the Chubu Bureau of Economy, Trade and Industry. ■ Title: AI Implementation Course Leading to Results - Learning Success Patterns and Practical Processes from Real Examples in Manufacturing Sites "We implemented AI, but it is not being used on-site and is left unattended" and "The implementation has become the goal without yielding results" - we have seen many such stumbling blocks in manufacturing sites. In the seminar, based on real examples, we will discuss common patterns for successful implementation that lead to results, pitfalls to avoid, and practical processes to ensure AI is continuously used. We will also propose specific measures for sites struggling with technology transfer and dependency on individuals. ■ Event Overview Date: July 3, 2026 (Friday) 13:30 - 16:00 Venue: TKP Meitetsu Nagoya Station Conference Center + Online Participation Fee: Free / Application Deadline: June 30 (Tuesday) Organizer: Chubu Bureau of Economy, Trade and Industry (Automotive Industry "Mikata Project") Co-presenter: Satoru Hayami, Waseda University For details and registration, please visit the official page of the Chubu Bureau of Economy, Trade and Industry. If you are struggling with AI implementation in manufacturing sites, please feel free to consult us, regardless of region or industry.

Jun 26, 2026

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We will be exhibiting at "Okayama Monozukuri NEXT 2026"!

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July 16 (Thursday) 10:00 AM - 6:00 PM Venue: Convex Okayama Small Exhibition Hall

Jun 26, 2026

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