[Free Webinar] Manual Curation Techniques for Accelerating AI/ML Drug Discovery Using SAR and ADME Data | Held on June 11 (Thursday)

By using GOSTAR, which comes with a parseable dataset, you can obtain the latest organized SAR information and focus on your research.

●Unmatched data quality and scale GOSTAR is one of the world's largest databases of low molecular weight compounds, curated manually by top experts. It is organized, integrated, and updated through manual curation, allowing for immediate use in analysis and AI model development. By using GOSTAR, you can free yourself from the tasks of collecting and organizing data, enabling you to focus your valuable time on the most important research activities. GOSTAR is one of the largest low molecular SAR databases in the world, containing approximately 9 million low molecular weight compounds and nearly 30 million SAR data points. The database is built from 80,000 patents filtered from about 40 million and 200,000 research articles filtered from about 10 million, with data extracted through manual work by experts and standardized and structured based on specified rules. 【Features】 ■ A centralized data source for one of the largest low molecular SAR information collections in the world ■ Automatically adjusted for display based on the type of ligand, making it easy to read ■ Sortable by any data column and color-coded based on values *For more details, please refer to the PDF materials or feel free to contact us.*

• Patent/Copyright related services

Comprehensive search of over 51,000 TPD compounds' structures, activities, and target information! Strongly supports drug discovery research with QMS-certified data.

■One of the largest and most reliable databases in the industry GOSTAR TPD is a specialized database that encompasses detailed structural information, activity data, and target protein information for over 51,000 target decomposition inducing agents (TPD) compounds. This product is certified with QMS (Quality Management System) and provides the latest and most reliable data through regular monthly updates. Researchers can quickly identify TPD compounds that meet their objectives using a flexible search function that combines multiple conditions of structure, target, and activity. It significantly reduces the effort of manually searching through vast literature and complex data. GOSTAR TPD dramatically improves the quality and speed of drug discovery research, strongly supporting the discovery of new therapeutic drugs. It provides an environment where complex TPD-related data can be understood simply and deeply, allowing researchers to focus on the core tasks of drug discovery. 【Features】 ■One of the largest domestic databases specializing in TPD structure, activity, and target ■High-quality data updated monthly, compatible with AI drug discovery ■Intuitive search UI maximizes research efficiency *For more details, please refer to the PDF materials or feel free to contact us.*

• Patent/Copyright related services

By using macromolecule data organized as a analyzable dataset, you can efficiently obtain the necessary information and focus on your research.

GOSTAR Large Molecules is a fully custom curation-type database focused on macromolecular drugs (peptides, oligonucleotides, antibodies). It aims to provide only the necessary data precisely according to the research theme and target molecules. ■Features 1. Macromolecule datasets constructed according to research themes 2. Manual curation by experts 3. Data structure designed for analysis and secondary use 4. Support for AI/machine learning applications 5. Flexible delivery formats (Excel, CSV, TSV)

• Patent/Copyright related services

Organized and standardized low molecular SAR data, in a usable format. GOSTAR Small Molecules reduces research preparation time.

●Unmatched Data Quality and Scale GOSTAR Small Molecules is one of the largest low molecular weight SAR databases in the world, containing over 11 million low molecular weight compounds and over 36.8 million SAR data points. Thanks to manual curation by specialized medicinal chemists and a three-tier quality control process certified by ISO 9001:2015, you can utilize organized and standardized reliable data directly in your research. 【Features】 ■ A centralized data source for one of the largest low molecular weight SAR information ■ Comprehensive understanding of low molecular weight SAR, including not only activity but also physicochemical properties and ADMET ■ Automatically adjusted for different types of ligands, making it easy to read ■ Sortable by any data column and color-coded based on values *For more details, please refer to the PDF document or feel free to contact us.

• Patent/Copyright related services

No need to provide the skeleton as a list in advance! It is automatically generated from the imported chemical structure.

"SARvision SM" is software that supports chemists in one of their important tasks: the examination of structure-activity relationships. With its unique Maximum Common Substructure (MCS) extraction engine, it can classify chemical structure data by scaffold, making SAR analysis easier. Scaffold-based data mining allows for evaluations that are closer to a chemist's intuition compared to descriptor-based clustering, proving effective in assessing screening data and formulating synthetic strategies during the Hit to Lead and lead optimization stages. 【NEW!】 A PROTAC analysis module has been released, allowing for routine and easy execution of SAR studies for bivalent ligands. For details, please visit the product page. 【Features】 ■ Automatically extracts common substructures from a group of structural formulas and presents a tree classified by scaffold. ■ Sorts scaffolds by physical properties or activity data, and allows dynamic filtering using sliders. ■ Rich graphic features (bar graphs, 2D scatter plots, 3D scatter plots). *For more information, please refer to the related links or feel free to contact us.

• Software (middle, driver, security, etc.)

We provide a spreadsheet optimized for array analysis! It can handle biopolymers.

"SARvision Biologics" is a desktop application that fills the gaps in existing biologics software. It provides foundational tools for reading and organizing data on biopolymers, as well as various tools to discover the relationships between sequences and activities. A spreadsheet optimized for sequence analysis is provided, allowing for the handling of biopolymers such as nucleic acids, proteins, and peptides, including non-natural amino acids and chemically modified residues. 【Features】 ■ Supports research on peptides, antibodies, and RNA ■ Capable of handling peptides that include non-natural amino acids, cyclization, and chemical modifications ■ Visualization of activity through heat maps ■ Highlights areas of interest *For more details, please refer to the PDF materials or feel free to contact us.

• Software (middle, driver, security, etc.)

Innovating patent research with highly comprehensive sequence searches.

PatSnap's Bio, specialized in the pharmaceutical, biotechnology, and agriculture industries, identifies patent information and a wealth of non-patent literature resources through the search of DNA, RNA, and protein sequences. It integrates with PatSnap's patent search and analysis tool, Analytics, allowing for more detailed patent analysis. Advanced data processing technology and a unique search AI algorithm significantly improve the FTO of biological sequences and reduce the risk of search omissions. 【Features】 ■ Large-scale sequence database Utilizes a highly comprehensive sequence database extracted from millions of patents, literature, and public databases through manual and AI methods. ■ Degenerate sequence search With cutting-edge degenerate search technology and proprietary AI, it enables degenerate sequences with various combinations. This enhances search comprehensiveness and reduces risk. ■ Extensive sequence search options Includes numerous sequence search options such as antibodies, motifs, fragments, and bulk searches of multiple sequences.

• Literature Management

Fukuda Co., Ltd. has been pursuing leak detection for 60 years and is committed to advancing the future of leak testing. 【 Supporting Various Leak Tests: Air Leak Test / Gas Leak Test (Hydrogen Gas, Helium Gas) 】 We develop, manufacture, and sell leak testing equipment to inspect airtightness and sealing properties. We will propose the appropriate testers and devices for each inspection target. 【 Target Industries and Examples of Inspection Targets 】 - Automotive Industry: Engines, FC components, valves and piping, various parts - Electronic Components Industry: Smartphones, keyless switches, various small sensors - Pharmaceuticals / Food / Cosmetics Industry: Bottle containers, syringes, vials, eye drop containers, pillow packaging, PTP packaging We will propose the most suitable leak testers for each industry. 【 ISO Certification 】JIS Q 9001:2015 (ISO 9001:2015)

Features: ● Equipped with Intel Core Ultra 9 285H/7 255H/5 225H ● DDR5 SODIMM x 2 (up to 128G) (sold separately) ● VGA Switch DDI x 1, LVDS colay eDP x 1, DDI x 2 ● USB 2.0 x 8, USB 3.2 Gen 2 x 4 ● PCIe [x1] x 4, PCIe [x4] x 1, PEG [x8] + [x4] + [x4] ● 2.5GbE x 1 ● COMe Type6 standard, 95mm x 95mm size ● Operating temperature -20~70℃ ● Sold separately ECB-920A: Development carrier board COM-MTHC6-FAN01: CPU fan COM-MTHC6-HSP01: Heat spreader (※ Heat dissipation is required in the enclosure)

Features: ● Equipped with Intel Core Ultra 7 255H/7 155H/5 225H/5 125H ● LPDDR5x 16GB/32GB/64GB onboard ● M.2 NVMe 256GB onboard ● USB 2.0 x 8, USB 3.2 (10Gbps) x 4 ● PCIe Gen 4 [x8] x 1, PCIe Gen 3 [x1] x 4, PCIe Gen 3 [x4] x 1 (2 lanes co-lay with SATA; BOM option) ● 2.5GbE x 2 ● COM-HPC Mini standard, size 95mm x 70mm ● Optional items ECB-980A: Development carrier board HPC-ARHm-FAN01: CPU fan HPC-ARHm-HSP01: Heat spreader (Note: heat dissipation is required in the enclosure)

Features: ● Processor: Qualcomm QCS6490 with Arm Cortex-A78 ×4 + Cortex-A55 ×4 (Octa-core) up to 2.7GHz ● LPDDR5 onboard memory (up to 8GB) ● Display: MIPI-DSI (4 lanes) ×1, DisplayPort ×1 ● USB 2.0 ×4 (one port supports OTG), Gigabit Ethernet ×2

In civil engineering sites during extreme heat, the surface temperature of the ground plates and the heat reflection significantly affect the working environment. In particular, steel plates tend to retain heat when exposed to sunlight, posing challenges for workers' heatstroke prevention and safety management. Hyper CLT ground plates are civil engineering materials utilizing wood CLT. As wooden ground plates, they can be used for temporary roads, access routes, heavy machinery work yards, material storage areas, and pedestrian pathways, making them a versatile alternative to steel plates in various civil engineering sites. In actual sites, there are cases where the surface temperature differs by about 20 degrees compared to steel plates, making them effective as a solution for heat prevention and reflection suppression. The 5×10 plate weighs approximately 230 kg, and the 5×20 plate weighs about 460 kg, making them lightweight and easy to handle even with small machinery, which helps reduce the burden of transportation, installation, and removal. They are materials that easily promote noise reduction, CO2 fixation, and environmental consideration unique to wood. Registered as a Ministry of Land, Infrastructure, Transport and Tourism NETIS technology "TH-250021-A," they can also be utilized for creative ideas and safety measures in public works. They are recommended for companies looking to reassess the summer site environment. We also accept inquiries for consultations and requests for materials tailored to site conditions. We can propose solutions for temporary plans during summer for both public and private civil engineering projects. Please feel free to consult with us.