Pharma IT & Digital Expo 2019 Exhibition

Process model library (reaction, crystallization, wet and dry grinding, spray drying, wet and dry granulation, blending, and tablet compression, etc.)

gPROMS Formulated Products is equipped with a library of process models for operations such as reactions, crystallization, wet and dry milling, spray drying, wet and dry granulation, blending, and tablet compression. In case studies applied to pharmaceutical processes, it enables consistent performance analysis of the entire system from active pharmaceutical ingredient (API) manufacturing through formulation processes to oral absorption risk analysis. ■ Solution crystallization analysis ■ Solid-liquid and solid-gas separation, classification, and granulation process analysis ■ Oral absorption analysis This product was developed with the cooperation of major pharmaceutical companies in Europe and the United States. By using mathematical models of raw materials, unit operations, and product performance, it allows for formulation design aimed at optimizing pharmaceuticals and their manufacturing. It enables faster screening of new formulation candidates against quality attributes, including in vivo performance and manufacturability.

• simulator
• Other analyses
• Analysis Services

Visualize continuous processes! For improving quality and reviewing production costs in active pharmaceutical ingredient manufacturing and formulation processes. *We provide support from demo tests to utilization follow-up.

This is a modeling tool developed in collaboration with a U.S. mega-pharma company. Recently, the pharmaceutical industry has been transitioning from batch production to continuous production, and it is being used for process design and control system considerations. It is a model library of gPROMS FormulatedProducts. In continuous production processes, advanced quality management (PAT, QbD, RTRT) becomes possible, as well as the ability to handle small-batch, multi-product production, but at the same time, high-precision process modeling technology becomes essential. If you have any inquiries such as "I want to reduce plant construction costs," "I want to increase production volume at existing plants," or "I want to improve product quality (particle size distribution)," please feel free to contact us! 【Features】 ■ Capable of steady-state and dynamic (dynamic) simulation ■ Easily handles multiple recycle streams ■ Allows for optimization considerations of plant design and operation methods ■ Can identify and estimate process equipment performance from test data ■ Provides graphical representation of batch plant operating procedures ■ Can be linked with crystallization process analysis libraries ■ Can be linked with oral absorption analysis libraries *For more details about the product, please download the PDF from the link below.

• simulator
• Other analyses
• Analysis Services

Introducing the technology of the gPROMS process modeling tool!

PSI Japan provides sales and technical consulting services for the simulation platform software "gPROMS." This catalog introduces the technology of the gPROMS process modeling tool. [Contents] ■ gPROMS Model Builder ■ Field-specific application software on the gPROMS platform ■ Hybrid simulation (coupled calculations with CFD) ■ Physical properties estimation package ■ Operator training simulator (OTS) *For more details, please refer to the catalog or feel free to contact us.

• simulator

For increasing production volume, optimizing operations, scale-up design, cost reduction, energy saving, etc.!

<gPROMS FormulatedProducts Crystallization Process Library> It can be used for various considerations and decision-making in production volume enhancement, operational improvement, and process optimization. To build efficient procedures (recipes) in the crystallization process, we will efficiently carry out operations in the following flow and achieve these within a short period (approximately 1 to 2 months). Modeling → Experiment → Model Verification (Parameter Estimation, Validation) → Process Optimization Consideration → Scale-Up Consideration The ability to automatically perform parameter estimation with the tool is a significant factor in reducing the consideration period. Additionally, since it is a kinetic model (expressing mechanisms in mathematical formulas), the number of parameters is kept to a necessary minimum. Furthermore, tools that automatically optimize cooling temperature reduction methods and patterns, the amount and timing of seed crystals, evaporation rates, and heating patterns are powerful, and scale-up may be conducted in conjunction with CFD (Computational Fluid Dynamics) simulations when necessary.

• Contract Analysis

On April 14, 2026 (Tuesday), Koichi Yokoyama, President and CEO of Paper Logic Co., Ltd., will be a speaker at the "JDDS Seminar - Solving the Revised Construction Business Act with DX!" JDDS (Juroku Densan Digital Service Co., Ltd.) is a company that provides digital solutions as a subsidiary of Juroku Financial Group. Currently, in the construction industry, the full enforcement of the "Revised Construction Business Act" has led to an increase in required documents, while the strong tradition of paper usage has resulted in a delay in digitalization. Additionally, the need to comply with the Electronic Bookkeeping Act has further burdened the field, bringing it close to its limits. In this seminar, our representative, Yokoyama, who has extensive experience as a certified public accountant and tax accountant, will thoroughly explain the key points to be aware of in practice regarding the "Revised Construction Business Act" and the "Electronic Bookkeeping Act" in an easy-to-understand manner.

On April 16, 2026 (Thursday), Koichi Yokoyama, President and CEO of Paper Logic Co., Ltd., will be a speaker at the "JDDS Seminar - Solving the Revised Construction Industry Law with DX!" JDDS (Juroku Densan Digital Service Co., Ltd.) is a company that provides digital solutions as a subsidiary of Juroku Financial Group. Currently, in the construction industry, the full enforcement of the "Revised Construction Industry Law" has led to an increase in required documents, while the strong tradition of paper usage has resulted in delays in digitization. Additionally, the need to comply with the Electronic Bookkeeping Preservation Law has further increased the burden on the field, nearing its limits. In this seminar, our representative, Yokoyama, who has extensive experience as a certified public accountant and tax accountant, will thoroughly explain the key points to be aware of in practice regarding the "Revised Construction Industry Law" and the "Electronic Bookkeeping Preservation Law" in an easy-to-understand manner.

[Speaker] Naoki Nakazaki, Partner Attorney, Anderson Mori & Tomotsune Foreign Law Joint Enterprise [Lecture Topics] 1. Overview of AI Principles and Code and its Position in Japan's AI Governance 2. How should we interpret "Comply or Explain"? 3. Framework for Disclosure 4. AI Learning and Copyright as Peripheral Issues 5. Comparison with Transparency Requirements of the EU AI Act 6. Comparison with Transparency Requirements at the State Law Level in the U.S. 7. Impact of AI Types (High-Risk AI, Conversational AI, Deepfakes) 8. Q&A *The content of the lecture may change according to the latest trends.

[Speakers] Taisuke Takamatsu, Principal Director, Accenture Ltd. Hiroki Masuyama, Manager [Presentation Topics] 1. Market structural changes brought about by the expansion of AI data centers 2. Redefining cooling and power equipment architecture through AI implementation 3. Newly emerging business opportunities in the cooling and power equipment sector 4. Winning strategies that Japanese companies should target 5. Q&A / Business card exchange

[Instructor] Naoki Kunimine, President of Thermal Design Lab, Inc. [Key Lecture Content] The use of AI has rapidly expanded, starting with ChatGPT. AI processing consumes several times more power than search processing, and deep learning requires large capacity and high-speed processing, causing the heat output of NVIDIA GPUs to exceed 1 kW. In the construction of data centers that aggregate these, not only ICT equipment but also cooling systems such as air conditioning consume a lot of power, making the reduction of PUE (Power Usage Effectiveness: total power consumption of the data center ÷ power consumption of IT equipment) a challenge. AI servers exceed the power consumption limit of 45 kW/Rack, known as the air cooling limit, and indirect/direct liquid cooling and immersion cooling are beginning to be adopted. Data centers are progressing in power reduction through the adoption of aisle containment and efficient air conditioning systems. This lecture will provide a broad explanation of the latest trends in these cooling technologies.