Pharma IT & Digital Expo 2019 Exhibition

Process model library (reaction, crystallization, wet and dry grinding, spray drying, wet and dry granulation, blending, and tablet compression, etc.)

gPROMS Formulated Products is equipped with a library of process models for operations such as reactions, crystallization, wet and dry milling, spray drying, wet and dry granulation, blending, and tablet compression. In case studies applied to pharmaceutical processes, it enables consistent performance analysis of the entire system from active pharmaceutical ingredient (API) manufacturing through formulation processes to oral absorption risk analysis. ■ Solution crystallization analysis ■ Solid-liquid and solid-gas separation, classification, and granulation process analysis ■ Oral absorption analysis This product was developed with the cooperation of major pharmaceutical companies in Europe and the United States. By using mathematical models of raw materials, unit operations, and product performance, it allows for formulation design aimed at optimizing pharmaceuticals and their manufacturing. It enables faster screening of new formulation candidates against quality attributes, including in vivo performance and manufacturability.

• simulator
• Other analyses
• Analysis Services

Visualize continuous processes! For improving quality and reviewing production costs in active pharmaceutical ingredient manufacturing and formulation processes. *We provide support from demo tests to utilization follow-up.

This is a modeling tool developed in collaboration with a U.S. mega-pharma company. Recently, the pharmaceutical industry has been transitioning from batch production to continuous production, and it is being used for process design and control system considerations. It is a model library of gPROMS FormulatedProducts. In continuous production processes, advanced quality management (PAT, QbD, RTRT) becomes possible, as well as the ability to handle small-batch, multi-product production, but at the same time, high-precision process modeling technology becomes essential. If you have any inquiries such as "I want to reduce plant construction costs," "I want to increase production volume at existing plants," or "I want to improve product quality (particle size distribution)," please feel free to contact us! 【Features】 ■ Capable of steady-state and dynamic (dynamic) simulation ■ Easily handles multiple recycle streams ■ Allows for optimization considerations of plant design and operation methods ■ Can identify and estimate process equipment performance from test data ■ Provides graphical representation of batch plant operating procedures ■ Can be linked with crystallization process analysis libraries ■ Can be linked with oral absorption analysis libraries *For more details about the product, please download the PDF from the link below.

• simulator
• Other analyses
• Analysis Services

Introducing the technology of the gPROMS process modeling tool!

PSI Japan provides sales and technical consulting services for the simulation platform software "gPROMS." This catalog introduces the technology of the gPROMS process modeling tool. [Contents] ■ gPROMS Model Builder ■ Field-specific application software on the gPROMS platform ■ Hybrid simulation (coupled calculations with CFD) ■ Physical properties estimation package ■ Operator training simulator (OTS) *For more details, please refer to the catalog or feel free to contact us.

• simulator

For increasing production volume, optimizing operations, scale-up design, cost reduction, energy saving, etc.!

<gPROMS FormulatedProducts Crystallization Process Library> It can be used for various considerations and decision-making in production volume enhancement, operational improvement, and process optimization. To build efficient procedures (recipes) in the crystallization process, we will efficiently carry out operations in the following flow and achieve these within a short period (approximately 1 to 2 months). Modeling → Experiment → Model Verification (Parameter Estimation, Validation) → Process Optimization Consideration → Scale-Up Consideration The ability to automatically perform parameter estimation with the tool is a significant factor in reducing the consideration period. Additionally, since it is a kinetic model (expressing mechanisms in mathematical formulas), the number of parameters is kept to a necessary minimum. Furthermore, tools that automatically optimize cooling temperature reduction methods and patterns, the amount and timing of seed crystals, evaporation rates, and heating patterns are powerful, and scale-up may be conducted in conjunction with CFD (Computational Fluid Dynamics) simulations when necessary.

• Contract Analysis

【Key Points of This Seminar】 - What is "push-type"? The true nature of common waste in the workplace - Basic principles of pull production and steps for on-site implementation - The concept of "downstream pull" to reduce work-in-progress and inventory - Case studies of companies that have made improvements - Specific methods for establishing a small start 【Target Audience: Improvement leaders and management】 - Those who feel there is too much "overproduction," "bottlenecks," and "wasteful movements" in the workplace - Those struggling with the gap between production planning and actual work - Those looking for ways to sustain improvement activities - Those who want to know practical methods for implementing TPS (Toyota Production System) ~ Visualizing waste to achieve "just enough, when needed" ~ "Is your workplace being 'pushed'?" In the workplace, issues such as "produced but not used" and "work-in-progress overflowing and halting flow" are common. Many of these problems may stem from push-type production, where items are made "just in case" rather than "because they are needed." A chain moves easily when "pulled," but what happens when it is "pushed"? ── This is precisely the difference between push and pull. We will teach you the system of production that "does not overproduce and does not stagnate" based on the concept of "pull production."

**Seminar Points** Improvement means changing standards for the better. There can be no improvement where there are no standards. If there are no standards, start by creating them. Standards are "rules." What to decide are "procedures," "methods," and "timing." This seminar is focused on determining "procedures" and creating "work instruction documents." **"Without standards, there is no improvement" — Learning from Toyota's teachings on documentation in the workplace** The source of Toyota's strength lies in the concepts of "improvement" and "standardization." At the core of this is a culture of making insights and skills visible in the workplace and documenting them. In other words, it is a system of knowledge transfer through documentation. Relying on the experience and intuition of veterans can be a strength in the workplace, but it also carries the risk that quality may change when people change. By ensuring that everyone performs tasks in the same way, we can achieve the same quality products (good products) in the same amount of time. First and foremost, the development of "work instruction documents" is essential. When presenting work instruction documents in video format, it is also a prerequisite that this "foundational document" is well established. *For more details, please download the PDF or contact us.*

We would like to extend our heartfelt congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will introduce a number of products, including our new product, the Pillow Packaging Full Air Tightness Inspection Machine MSQ-2003. We sincerely apologize for the inconvenience during your busy schedule, but we would like to invite you to visit us at this opportunity. 【 Exhibition Name 】 JAPAN PACK 2025 Japan Packaging Industry Exhibition https://www.japanpack.jp/ 【 Dates 】 October 7 (Tuesday) to October 10 (Friday), 2025 *4 days 10:00 AM to 5:00 PM 【 Venue / Booth Number 】 Tokyo Big Sight / East Hall 8, Booth 8-505

Kobayashi Co., Ltd. will be exhibiting at the 5th Sustainable Materials Exhibition (SUSMA) held at Makuhari Messe. This exhibition is a specialized event focused on sustainable materials (environmentally friendly materials) and their manufacturing and recycling technologies. Technicians, product planners, and management from various industrial sectors such as electronics, automotive, batteries, and construction materials, as well as manufacturers of food, beverages, daily necessities, and miscellaneous goods will be attending. We sincerely look forward to your visit.

The "Team Cohesion and Team Strength Development Seminar" is an online seminar that provides techniques for demonstrating leadership that drives members and achieves results as a team. "Become a Leader Who Unites the Team from an Excellent Player" The cornerstone of the workplace is the leadership class, such as supervisors and team leaders. It is crucial for these individuals, who know the front lines, to demonstrate leadership that drives the work and leads the members. No matter how excellent a player is, if they work alone, they will only ever be as strong as one horsepower. It’s about demonstrating strength as a team! In other words, it’s about moving people… and that requires a deep understanding of others and the ability to respond. I believe that the most important aspects are the perspective and execution needed to involve those around you, align the vectors, and propel the team forward. [What You Will Learn] ■ Delegating Work ⇒ The key points and tips for confidently delegating work instead of taking it all on yourself. ■ The Four Windows of Interpersonal Relationships ⇒ How to deeply understand yourself and help others recognize you better. ■ Mentoring Skills for Junior Colleagues ⇒ Analyzing the guidance necessary for the "Hō-Ren-Sō" (reporting, communicating, and consulting) to function through short case studies. *For more details, please download the PDF or contact us.