Nova Biomedical March 22 (Friday) Holding [Notice of the 18th Annual Meeting of the Japanese Society for Regenerative Medicine Co-hosted Academic Seminar]

Presentation of verification materials for iPS cell culture: Simultaneous measurement and analysis of up to 16 items in 4 minutes and 30 seconds! Strong support for improving culture efficiency.

There is data indicating that "an appropriate culture medium environment correlates with an increase in cell numbers," which necessitates the creation and adjustment of an appropriate culture medium environment to promote efficient cell culture. Are you unable to execute this due to the "time required for measurement and analysis" being a bottleneck? The cell culture environment automatic analysis device 'BioProfile FLEX2' can analyze the components of cell culture media for up to 16 items in just 4.5 minutes. It allows for rapid quantification of culture conditions such as metabolism, proliferation, and differentiation, contributing to the establishment of a culture environment aimed at mass production. ★ We are currently offering materials that investigate the correlation between changes in medium components and cell numbers in iPS cell culture. 【Features】 ■ Simultaneous analysis of up to 16 items ■ Rapid measurement time: as short as 2 minutes, up to 4 minutes and 30 seconds (depending on measurement items) ■ Capable of measuring consumption and production rates of major metabolites ■ Compatible with multiple shapes of sample containers ■ Equipped with an auto-sampling function for continuous measurement of samples *For more details, please refer to the materials available for download in PDF format.

• Other measurement, recording and measuring instruments
• Analytical Equipment and Devices

Presentation of Cell Culture Medium Analysis Explanation Materials: An analytical device capable of simultaneous measurement and analysis of up to 16 items in 4 minutes and 30 seconds! For creating appropriate culture environments and improving efficiency in compliance with GMP.

The "BioProfile FLEX2" is an automated analysis device for cell culture environments that can simultaneously analyze up to 16 components of cell culture media. In just 4.5 minutes, it quantifies culture conditions such as metabolism, proliferation, and differentiation, contributing to the efficiency of "continuity assessment of the cell manufacturing process," "creating a culture environment with an eye on mass production," and "quality control and documentation of standards in line with GMP compliance." It is equipped with sample containers of various shapes, requiring a small sample volume of 135 to 265 μL. For chemical substances and gas measurements, it uses sensor cards that do not require electrode maintenance. 【Features】 ■ Capable of simultaneous analysis of up to 16 items ■ Rapid measurement time: as short as 2 minutes and as long as 4 minutes and 30 seconds (depending on the measurement item) ■ Can measure the consumption and production rates of major metabolites 【Exhibition Information】 Name: BioJapan 2024 Venue: Pacifico Yokohama D-39 Date: October 9-11, 2024 Featured Products: Demonstration of "BioProfile FLEX2" and "BioProfile FAST CDV" media analysis! A 70% off campaign for "Stat Profile Prime" is currently underway! (Until the end of December) *Analysis explanation materials are currently available! Please check from "PDF Download."

• Other physicochemical equipment

An automatic analysis device for cell culture environments that achieves "shortened measurement time" and "significant reduction in sample volume"! All 16 items can be measured with just a small amount of sample.

The "BioProfile FLEX2" is an analytical device that utilizes micro-sensor technology. This technology allows the "BioProfile FLEX2" to achieve "reduced maintenance related to electrodes," "shortened measurement time," and "significantly reduced sample volume," making it an automatic analysis device for cell culture environments. It can measure all 16 parameters with a minimal sample volume, completing all 16 measurements in just 4 minutes and 30 seconds, or 2 minutes for individual modules. 【Features】 ■ Monitoring the progress of cell culture ■ Quantification of key components in the culture medium ■ Early detection of abnormalities through regular monitoring ■ Capability to measure multiple parameters with one device, consolidating the functions of multiple devices into one ■ Numerical backing for the timing of medium exchange *For more details, please request documentation or view the PDF data available for download.

• Other physicochemical equipment

Presentation of verification materials exploring the application to the evaluation of cell quality and experimental systems!

This document is a verification report that measures parameters in the culture supernatant during the maintenance culture of iPS cells and the differentiation induction process from iPS cells to dopamine-producing neural progenitor cells, exploring applications for evaluating cell quality and experimental systems. In addition to the experimental content and the composition of reagents and media, it discusses differentiation induction and maintenance culture. 【Contents】 ■ Purpose ■ Experimental Content ■ Reagents and Media Composition - Differentiation induction into neural progenitor cells - iPS cell culture ■ Discussion *For more details, please refer to the PDF document or feel free to contact us.

• others

A rapid, simple, and compact-sized analysis device! Providing cost-effective analysis.

The "Stat Profile Prime" is a cell culture medium analysis device that can measure a total of 9 items, including pH, PCO2, PO2, and Na+. Calibration and precision management are automatically performed to ensure that measurements of the 9 items can be conducted in approximately 1 minute at all times. Additionally, the Prime's individual cartridge system can be attached to the device immediately after opening, and the replacement process takes only a few seconds, maximizing the usable time of the analysis device. 【Features】 ■ Measurement of 9 items (pH, PCO2, PO2, Na+, K+, Cl, Ca+, Gluc, Lac) ■ Zero maintenance cartridge technology ■ High-speed throughput and small sample volumes ■ Automatic QC function *For more details, please refer to the PDF document or feel free to contact us.

• Other Culture
• Other analytical and testing equipment

We would like to extend our heartfelt congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will showcase a variety of products, including new ones. We sincerely invite you to visit us during this busy time. 【 Exhibition Name 】 Automotive Technology Exhibition 2025 YOKOHAMA https://aee.expo-info.jsae.or.jp/ja/yokohama/ (An "online exhibition" will also be held during and around the event period) 【 Dates 】 May 21 (Wednesday) - 23 (Friday), 2024 10:00 AM - 6:00 PM *On the final day, 9:00 AM - 4:00 PM (Online exhibition: May 14 (Wednesday) - June 4 (Wednesday)) 【 Venue 】 Pacifico Yokohama (1-1-1 Minatomirai, Nishi-ku, Yokohama, Kanagawa Prefecture) Our booth number: "Concourse 505"

We would like to extend our heartfelt congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will showcase a variety of products, including new ones. We sincerely apologize for the inconvenience during your busy schedule, but we would like to invite you to attend this event. 【 Exhibition Name 】 27th INTERPHEX Week Tokyo https://www.interphex.jp/tokyo/ja-jp.html 【 Dates 】 July 9 (Wednesday) - 11 (Friday), 2025 10:00 AM - 5:00 PM 【 Venue 】 Tokyo Big Sight (3-11-1 Ariake, Koto-ku, Tokyo 135-0063)

[Lecturer] Taku Ito, Partner, Mori Hamada & Matsumoto Foreign Law Joint Enterprise Yoshifumi Nagakubo, Senior Associate [Key Lecture Content] As we move towards a carbon-neutral society, the large-scale introduction of renewable energy sources is progressing, making the enhancement of market design that balances stable electricity supply and economic efficiency an urgent issue. In this context, the "simultaneous market," which integrates the trading of electricity (kWh) and adjustment capacity (ΔkW), is being discussed as a core component of future electricity systems, and serious considerations for its implementation are underway. In this lecture, a lawyer who has led discussions at the forefront of national system design will explain in an easy-to-understand manner the background and necessity of the simultaneous market, as well as the overall picture of its complex mechanisms, based on practical experience. Furthermore, the lecture will clearly outline the latest developments in current discussions, realistic challenges for implementation, and prospects for future electricity business in Japan, incorporating perspectives and insights as a system designer and practitioner.

[Instructor] Hirokazu Shibata, President and CEO of ZAZU Design Co., Ltd. [Key Lecture Content] As the importance of heat dissipation design increases in daily operations, it is necessary to study a range of books on thermal engineering to learn the overall picture of heat dissipation design. However, books on thermal engineering typically start with the basics of heat transfer and cover topics such as temperature boundary layers and dimensionless numbers related to heat transfer, making it quite difficult for beginners to grasp the overall picture in a short period. This seminar is aimed at engineers who will begin thermal design in the future, focusing on various heat dissipation devices as specific subjects. The goal is to understand the basics of thermal design while learning about the characteristics and usage of these heat dissipation devices. After attending this seminar, participants are expected to acquire knowledge equivalent to that gained from studying a range of thermal engineering books. [Lecture Topics] 1. Current Status and Challenges of Thermal Design 2. How "Thermal Resistance" Determines Heat Dissipation Pathways 3. Fundamental Laws Governing Heat Transfer 4. Air Cooling through Heat Transfer 5. Heat Diffusion through Thermal Conduction 6. Heat Transfer via Two-Phase Flow of Gas and Liquid 7. Q&A Session

[Lecturers] Accenture Ltd. Business Consulting Division Strategy Group, Technology Strategy Senior Manager Mamoru Yoneshige Accenture Ltd. Technology Consulting Division CDAI Consulting Principal Director Hiromichi Sugiyama [Key Lecture Content] While system development using AI agents is gaining attention, the challenges of AI-driven development in brownfield projects for enterprises with existing assets and technical debt are significantly greater. The introduction of coding support tools alone does not lead to company-wide transformation, and there exists a structural gap between the success of Proof of Concept (PoC) and the success of company-wide deployment. In this lecture, based on practical insights from Accenture's comprehensive support from strategy formulation to implementation, we will systematically explain the essentials for successful company-wide deployment, including the six principles of AI-driven development, categorization of brownfield types and deployment strategies, context engineering, the systematization of methodologies such as harness engineering and specification-driven approaches, promotion systems and in-house production strategies, and KPI design as a management agenda.