Nova Biomedical March 22 (Friday) Holding [Notice of the 18th Annual Meeting of the Japanese Society for Regenerative Medicine Co-hosted Academic Seminar]

Presentation of verification materials for iPS cell culture: Simultaneous measurement and analysis of up to 16 items in 4 minutes and 30 seconds! Strong support for improving culture efficiency.

There is data indicating that "an appropriate culture medium environment correlates with an increase in cell numbers," which necessitates the creation and adjustment of an appropriate culture medium environment to promote efficient cell culture. Are you unable to execute this due to the "time required for measurement and analysis" being a bottleneck? The cell culture environment automatic analysis device 'BioProfile FLEX2' can analyze the components of cell culture media for up to 16 items in just 4.5 minutes. It allows for rapid quantification of culture conditions such as metabolism, proliferation, and differentiation, contributing to the establishment of a culture environment aimed at mass production. ★ We are currently offering materials that investigate the correlation between changes in medium components and cell numbers in iPS cell culture. 【Features】 ■ Simultaneous analysis of up to 16 items ■ Rapid measurement time: as short as 2 minutes, up to 4 minutes and 30 seconds (depending on measurement items) ■ Capable of measuring consumption and production rates of major metabolites ■ Compatible with multiple shapes of sample containers ■ Equipped with an auto-sampling function for continuous measurement of samples *For more details, please refer to the materials available for download in PDF format.

• Other measurement, recording and measuring instruments
• Analytical Equipment and Devices

Presentation of Cell Culture Medium Analysis Explanation Materials: An analytical device capable of simultaneous measurement and analysis of up to 16 items in 4 minutes and 30 seconds! For creating appropriate culture environments and improving efficiency in compliance with GMP.

The "BioProfile FLEX2" is an automated analysis device for cell culture environments that can simultaneously analyze up to 16 components of cell culture media. In just 4.5 minutes, it quantifies culture conditions such as metabolism, proliferation, and differentiation, contributing to the efficiency of "continuity assessment of the cell manufacturing process," "creating a culture environment with an eye on mass production," and "quality control and documentation of standards in line with GMP compliance." It is equipped with sample containers of various shapes, requiring a small sample volume of 135 to 265 μL. For chemical substances and gas measurements, it uses sensor cards that do not require electrode maintenance. 【Features】 ■ Capable of simultaneous analysis of up to 16 items ■ Rapid measurement time: as short as 2 minutes and as long as 4 minutes and 30 seconds (depending on the measurement item) ■ Can measure the consumption and production rates of major metabolites 【Exhibition Information】 Name: BioJapan 2024 Venue: Pacifico Yokohama D-39 Date: October 9-11, 2024 Featured Products: Demonstration of "BioProfile FLEX2" and "BioProfile FAST CDV" media analysis! A 70% off campaign for "Stat Profile Prime" is currently underway! (Until the end of December) *Analysis explanation materials are currently available! Please check from "PDF Download."

• Other physicochemical equipment

An automatic analysis device for cell culture environments that achieves "shortened measurement time" and "significant reduction in sample volume"! All 16 items can be measured with just a small amount of sample.

The "BioProfile FLEX2" is an analytical device that utilizes micro-sensor technology. This technology allows the "BioProfile FLEX2" to achieve "reduced maintenance related to electrodes," "shortened measurement time," and "significantly reduced sample volume," making it an automatic analysis device for cell culture environments. It can measure all 16 parameters with a minimal sample volume, completing all 16 measurements in just 4 minutes and 30 seconds, or 2 minutes for individual modules. 【Features】 ■ Monitoring the progress of cell culture ■ Quantification of key components in the culture medium ■ Early detection of abnormalities through regular monitoring ■ Capability to measure multiple parameters with one device, consolidating the functions of multiple devices into one ■ Numerical backing for the timing of medium exchange *For more details, please request documentation or view the PDF data available for download.

• Other physicochemical equipment

Presentation of verification materials exploring the application to the evaluation of cell quality and experimental systems!

This document is a verification report that measures parameters in the culture supernatant during the maintenance culture of iPS cells and the differentiation induction process from iPS cells to dopamine-producing neural progenitor cells, exploring applications for evaluating cell quality and experimental systems. In addition to the experimental content and the composition of reagents and media, it discusses differentiation induction and maintenance culture. 【Contents】 ■ Purpose ■ Experimental Content ■ Reagents and Media Composition - Differentiation induction into neural progenitor cells - iPS cell culture ■ Discussion *For more details, please refer to the PDF document or feel free to contact us.

• others

A rapid, simple, and compact-sized analysis device! Providing cost-effective analysis.

The "Stat Profile Prime" is a cell culture medium analysis device that can measure a total of 9 items, including pH, PCO2, PO2, and Na+. Calibration and precision management are automatically performed to ensure that measurements of the 9 items can be conducted in approximately 1 minute at all times. Additionally, the Prime's individual cartridge system can be attached to the device immediately after opening, and the replacement process takes only a few seconds, maximizing the usable time of the analysis device. 【Features】 ■ Measurement of 9 items (pH, PCO2, PO2, Na+, K+, Cl, Ca+, Gluc, Lac) ■ Zero maintenance cartridge technology ■ High-speed throughput and small sample volumes ■ Automatic QC function *For more details, please refer to the PDF document or feel free to contact us.

• Other Culture
• Other analytical and testing equipment

[Lecture Topics] 1. Trends in Policies for Decarbonization of Housing and Buildings Tetsuya Hirayama, Deputy Director, Housing Bureau, Ministry of Land, Infrastructure, Transport and Tourism (in charge of architectural planning) 2. Construction Circular Economy - Expanding Horizontal Recycling for Achieving Sustainable Construction Takahiro Moritomi, Analyst, Social Infrastructure Team, Next Generation Infrastructure and Services Office, Industry Research Department, Mizuho Bank, Ltd. 3. Beyond "Scrap and Build" Aiming for the Realization of "Circular Design Build®" Shoichi Fukui, Senior Chief Expert, Sustainability Promotion Department, Management Planning Office, Takenaka Corporation

[Instructor] Attorney Kurato Suzuki, Irokawa Law Office [Key Lecture Content] Due to the amendments to the Comprehensive Promotion Law for Labor Policies, starting from October 1, 2026, employers will be required to take necessary measures in employment management regarding customer harassment (Kasu Hara) and sexual harassment against job seekers (Job Hunting Sexual Harassment). In line with this, companies will need to prepare for practical implementation before the enforcement date, based on the guidelines published by the Ministry of Health, Labour and Welfare. This includes developing internal regulations, establishing consultation and response systems, raising awareness within the company, and determining judgment and response methods on-site. This seminar will organize the setting of job hunting rules related to job hunting sexual harassment, internal awareness, and key points for regulatory development. It will also explain the distinction between legitimate complaints and customer harassment, judgment, documentation, and response on-site, the establishment of a company-wide system, regulatory development considering dispute risks, and points that are easily overlooked. The Human Resources, Labor, Legal, and Compliance departments will systematically organize the response matters that need to be confirmed in preparation for the enforcement on October 1, 2026, from the perspectives of guideline compliance and on-site operations. [Lecture Items] 1. Job Hunting Sexual Harassment 2. Customer Harassment 3. Q&A

[Speaker] Mr. Itsuki Wakayama, Project General Manager, Technology Promotion Unit, Low Carbon Solutions Division, INPEX Corporation [Key Lecture Content] The greatest advantage of synthetic methane production through CO2 methanation technology is that it enables decarbonization without significant additions or modifications to all existing natural gas and city gas infrastructure. At INPEX, after two NEDO commissioned projects, we have been conducting the development of practical application technology with a capacity of 400 Nm3-CO2/h, one of the largest in the world, as a subsidized project by NEDO since the fiscal year 2021. By the fiscal year 2025, we aim to achieve the injection of synthetic methane produced during the demonstration operation of the test facility. This presentation will provide detailed information on the results of the NEDO project for the fiscal year 2025, including the current status of the latest test facilities. [Presentation Items] 1. INPEX's efforts towards net zero by 2050 2. Policy trends related to CO2 methanation 3. Challenges of CO2 methanation 4. Results of the NEDO practical application technology development project with a capacity of 400 Nm3-CO2/h for the fiscal year 2025 5. Future commercialization prospects and challenges 6. Q&A / Business card exchange

[Speaker] Mr. Satoru Shimizu, President and CEO of Okunote Inc. [Key Lecture Content] Generative AI is not a "magic wand," but a "mirror" that reflects the questions of the user. In this lecture, based on my book "The 'Super' Planning Techniques Practiced by Competition Disruptors: Seven Creative Steps to Lead Winning Strategies with the 'Art of Questioning'," I will explain how to overcome the challenges of proposals being rejected, not moving forward within the company, and not being executed on-site through interactions with AI. I will introduce the entire process of planning, linking it with AI utilization, from question design to hypothesis destruction, structuring materials from the decision-maker's perspective, forming internal consensus, managing execution, and turning reflections into assets. In the latter part of the workshop (exclusive to on-site participants), you will actually formulate questions and refine your dialogue with AI, taking home usable "art of questioning" techniques for tomorrow. [Lecture Items] 1. Orientation: AI is a "mirror," not a "magic wand." 2. Enhancing the precision of planning through "question design" and "hypothesis destruction." 3. Structuring materials from the decision-maker's perspective to create "acceptable" proposals. 4. Forming consensus that transcends internal barriers. 5. Mechanisms that prevent execution from stopping and turning experiences into assets through reflection. 6. Habitualizing AI as a "partner" and the roles humans will take on in the AI era.

【Exhibition Overview】 A collection of products related to data centers, which are at the core of AI infrastructure, gathered in one place.