[1/27 Public On-Demand Webinar] Accelerating the Development and Commercialization of Biopharmaceuticals: Latest Information on Nova's Cell Culture Analysis and Automation Innovations.

Presentation of verification materials exploring the application to the evaluation of cell quality and experimental systems!

This document is a verification report that measures parameters in the culture supernatant during the maintenance culture of iPS cells and the differentiation induction process from iPS cells to dopamine-producing neural progenitor cells, exploring applications for evaluating cell quality and experimental systems. In addition to the experimental content and the composition of reagents and media, it discusses differentiation induction and maintenance culture. 【Contents】 ■ Purpose ■ Experimental Content ■ Reagents and Media Composition - Differentiation induction into neural progenitor cells - iPS cell culture ■ Discussion *For more details, please refer to the PDF document or feel free to contact us.

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Accelerating the development of the COVID-19 vaccine - Rapid simultaneous measurement of multiple items with trace samples using the automatic analysis device for cell culture environments, FLEX2.

To prevent the spread of the novel coronavirus (COVID-19), the urgent development of vaccines is required. It is said that managing the culture environment is crucial in the process of vaccine research and development involving host cell cultures. The "BioProfile" series of cell culture environment analysis devices from Nova Biomedical is widely adopted by major pharmaceutical companies and institutions in Japan and around the world for managing culture environments in vaccine research, development, and manufacturing processes. At Nova Biomedical, we hope to contribute, albeit modestly, to the development of COVID-19 vaccines by offering flexible purchasing programs tailored to your budget. For more details, please contact us through the inquiry form, and we will respond promptly. We also have materials available for cell culture analysis using our devices. 【Features】 - Monitoring the progress of cell culture - Quantification of key components in the culture medium - Early detection of abnormalities in the culture environment through regular monitoring - Capability to measure multiple items with one device, significantly reducing measurement time by consolidating the functions of multiple devices into one - Numerical backing for the timing of medium changes - Maintenance-free and sensor card-based, reducing the workload for researchers on equipment maintenance

• Other physicochemical equipment

An automatic analysis device for cell culture environments that achieves "shortened measurement time" and "significant reduction in sample volume"! All 16 items can be measured with just a small amount of sample.

The "BioProfile FLEX2" is an analytical device that utilizes micro-sensor technology. This technology allows the "BioProfile FLEX2" to achieve "reduced maintenance related to electrodes," "shortened measurement time," and "significantly reduced sample volume," making it an automatic analysis device for cell culture environments. It can measure all 16 parameters with a minimal sample volume, completing all 16 measurements in just 4 minutes and 30 seconds, or 2 minutes for individual modules. 【Features】 ■ Monitoring the progress of cell culture ■ Quantification of key components in the culture medium ■ Early detection of abnormalities through regular monitoring ■ Capability to measure multiple parameters with one device, consolidating the functions of multiple devices into one ■ Numerical backing for the timing of medium exchange *For more details, please request documentation or view the PDF data available for download.

• Other physicochemical equipment

Presentation of verification materials for iPS cell culture: Simultaneous measurement and analysis of up to 16 items in 4 minutes and 30 seconds! Strong support for improving culture efficiency.

There is data indicating that "an appropriate culture medium environment correlates with an increase in cell numbers," which necessitates the creation and adjustment of an appropriate culture medium environment to promote efficient cell culture. Are you unable to execute this due to the "time required for measurement and analysis" being a bottleneck? The cell culture environment automatic analysis device 'BioProfile FLEX2' can analyze the components of cell culture media for up to 16 items in just 4.5 minutes. It allows for rapid quantification of culture conditions such as metabolism, proliferation, and differentiation, contributing to the establishment of a culture environment aimed at mass production. ★ We are currently offering materials that investigate the correlation between changes in medium components and cell numbers in iPS cell culture. 【Features】 ■ Simultaneous analysis of up to 16 items ■ Rapid measurement time: as short as 2 minutes, up to 4 minutes and 30 seconds (depending on measurement items) ■ Capable of measuring consumption and production rates of major metabolites ■ Compatible with multiple shapes of sample containers ■ Equipped with an auto-sampling function for continuous measurement of samples *For more details, please refer to the materials available for download in PDF format.

• Other measurement, recording and measuring instruments
• Analytical Equipment and Devices

Softex Corporation will be exhibiting at the "40th Electro Test Japan" held at Tokyo Big Sight. At our booth, we will showcase the micro-focus X-ray inclined CT inspection device "SHRα," which demonstrates its power on components such as implemented multilayer boards and three-dimensional structures that have been difficult to inspect until now. [Booth Number: East Hall 5 E15-17] We sincerely look forward to your visit.

Tohsan Electronic Equipment is exhibiting our product "ePI-09" used in calligraphy robots and "T-Shirt-kun" related goods at MOBIO (Monozukuri Business Center Osaka). Period: November 4, 2025 - November 27, 2025 Location: MOBIO The "ePI-09" is one of the smallest in the industry, yet it features 4-axis synchronous control and various interpolation functions (such as linear, arc, and helical). It is compatible with Raspberry Pi, has a rich API, and enables low-cost and short-term development. It can be stacked with up to 8 units and supports control of up to 32 axes. Additionally, at the "T-Shirt-kun" related exhibition, we are showcasing actual printed T-shirts and flyers with coupons. You can closely see the quality of the products and the image of their use. We hope you stop by!

Kanadebia Co., Ltd. will be exhibiting at the "9th Railway Technology Exhibition 2025 Mass-Trans Innovation Japan 2025" held at Makuhari Messe. This exhibition has been held since 2010 as a comprehensive trade fair where various railway-related technologies, including railway and transportation systems, infrastructure technology, facilities, power, transportation, operation management, vehicles, interiors, and passenger services, come together. Please be sure to check out the "Railway Camera System" offered by Kanadebia. We sincerely look forward to your visit.

On November 20, 2025 (Thursday) and December 2, 2025 (Tuesday) from 11:00 to 14:00, our representative, certified public accountant and tax accountant Koichi Yokoyama, will be speaking at a free webinar hosted by Otsuka Shokai. He will explain important points to be aware of regarding the revised Construction Industry Law. [Construction Industry Law / Public Works Appropriateness Promotion Law] - Prevention of omissions in the description of construction contracts - Obligation to notify "risk" information before the contractor's contract - Mutual exchange of original documents for construction contracts - Digitization of estimates, contracts, and order forms/acceptance letters We are entering an era where contracts must be documented in writing and stored electronically. At Paperlogic, we fully support companies that are transitioning from paper to digital. We also offer free consultations with certified public accountants and tax accountants, so please join us!

We would like to inform you that we will be exhibiting our products at the Membrane Symposium 2025. If you are planning to attend, please feel free to stop by. ❚ Products Scheduled for Exhibition - Artificial Lipid Bilayer Experimental Device | Orbit mini You can easily measure channel activity at the single-molecule level. This device allows for the formation of lipid membranes, reconstitution of membrane proteins, and single-channel measurements in experiments using artificial lipid bilayers, all performed with just a micropipette, enabling functional and structural analysis of target membrane proteins and evaluation of drug effects. - Liposome Preparation Device | Vesicle Prep Pro This is the world's first device that can produce giant unilamellar vesicles (GUVs) with diameters ranging from 1 to 30 μm without organic solvents, using the electroporation method (vibrating hydrated lipid films in an alternating electric field). - Auto Patch Clamp System | Port-a-Patch mini This compact system eliminates the need for a microscope, vibration isolation table, manipulator, and Faraday cage, which are typically required for conventional patch clamp experiments. It allows for easy data acquisition and verification without the need for specialized skills or experience.