[1/27 Public On-Demand Webinar] Accelerating the Development and Commercialization of Biopharmaceuticals: Latest Information on Nova's Cell Culture Analysis and Automation Innovations.

Presentation of verification materials exploring the application to the evaluation of cell quality and experimental systems!

This document is a verification report that measures parameters in the culture supernatant during the maintenance culture of iPS cells and the differentiation induction process from iPS cells to dopamine-producing neural progenitor cells, exploring applications for evaluating cell quality and experimental systems. In addition to the experimental content and the composition of reagents and media, it discusses differentiation induction and maintenance culture. 【Contents】 ■ Purpose ■ Experimental Content ■ Reagents and Media Composition - Differentiation induction into neural progenitor cells - iPS cell culture ■ Discussion *For more details, please refer to the PDF document or feel free to contact us.

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Accelerating the development of the COVID-19 vaccine - Rapid simultaneous measurement of multiple items with trace samples using the automatic analysis device for cell culture environments, FLEX2.

To prevent the spread of the novel coronavirus (COVID-19), the urgent development of vaccines is required. It is said that managing the culture environment is crucial in the process of vaccine research and development involving host cell cultures. The "BioProfile" series of cell culture environment analysis devices from Nova Biomedical is widely adopted by major pharmaceutical companies and institutions in Japan and around the world for managing culture environments in vaccine research, development, and manufacturing processes. At Nova Biomedical, we hope to contribute, albeit modestly, to the development of COVID-19 vaccines by offering flexible purchasing programs tailored to your budget. For more details, please contact us through the inquiry form, and we will respond promptly. We also have materials available for cell culture analysis using our devices. 【Features】 - Monitoring the progress of cell culture - Quantification of key components in the culture medium - Early detection of abnormalities in the culture environment through regular monitoring - Capability to measure multiple items with one device, significantly reducing measurement time by consolidating the functions of multiple devices into one - Numerical backing for the timing of medium changes - Maintenance-free and sensor card-based, reducing the workload for researchers on equipment maintenance

• Other physicochemical equipment

An automatic analysis device for cell culture environments that achieves "shortened measurement time" and "significant reduction in sample volume"! All 16 items can be measured with just a small amount of sample.

The "BioProfile FLEX2" is an analytical device that utilizes micro-sensor technology. This technology allows the "BioProfile FLEX2" to achieve "reduced maintenance related to electrodes," "shortened measurement time," and "significantly reduced sample volume," making it an automatic analysis device for cell culture environments. It can measure all 16 parameters with a minimal sample volume, completing all 16 measurements in just 4 minutes and 30 seconds, or 2 minutes for individual modules. 【Features】 ■ Monitoring the progress of cell culture ■ Quantification of key components in the culture medium ■ Early detection of abnormalities through regular monitoring ■ Capability to measure multiple parameters with one device, consolidating the functions of multiple devices into one ■ Numerical backing for the timing of medium exchange *For more details, please request documentation or view the PDF data available for download.

• Other physicochemical equipment

Presentation of verification materials for iPS cell culture: Simultaneous measurement and analysis of up to 16 items in 4 minutes and 30 seconds! Strong support for improving culture efficiency.

There is data indicating that "an appropriate culture medium environment correlates with an increase in cell numbers," which necessitates the creation and adjustment of an appropriate culture medium environment to promote efficient cell culture. Are you unable to execute this due to the "time required for measurement and analysis" being a bottleneck? The cell culture environment automatic analysis device 'BioProfile FLEX2' can analyze the components of cell culture media for up to 16 items in just 4.5 minutes. It allows for rapid quantification of culture conditions such as metabolism, proliferation, and differentiation, contributing to the establishment of a culture environment aimed at mass production. ★ We are currently offering materials that investigate the correlation between changes in medium components and cell numbers in iPS cell culture. 【Features】 ■ Simultaneous analysis of up to 16 items ■ Rapid measurement time: as short as 2 minutes, up to 4 minutes and 30 seconds (depending on measurement items) ■ Capable of measuring consumption and production rates of major metabolites ■ Compatible with multiple shapes of sample containers ■ Equipped with an auto-sampling function for continuous measurement of samples *For more details, please refer to the materials available for download in PDF format.

• Other measurement, recording and measuring instruments
• Analytical Equipment and Devices

【Seminar Overview】 The construction industry faces many challenges, including labor shortages, regulations on working hours, and the need for operational efficiency. Additionally, the aging workforce presents significant issues, and there is a concerning trend of high turnover rates among younger employees who are supposed to carry on the skills and knowledge. In this seminar, we will discuss the causes of turnover based on case studies and explain key points on how advancing IT can help reduce turnover rates.

We would like to extend our heartfelt congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will introduce a number of products, including our new product, the Pillow Packaging Full Air Tightness Inspection Machine MSQ-2003. We sincerely apologize for the inconvenience during your busy schedule, but we would like to invite you to visit us at this opportunity. 【 Exhibition Name 】 JAPAN PACK 2025 Japan Packaging Industry Exhibition https://www.japanpack.jp/ 【 Dates 】 October 7 (Tuesday) to October 10 (Friday), 2025 *4 days 10:00 AM to 5:00 PM 【 Venue / Booth Number 】 Tokyo Big Sight / East Hall 8, Booth 8-505

We will be exhibiting at the "Monozukuri Fair 2025" held at Marine Messe Fukuoka from October 15 (Wednesday) to October 17 (Friday). "For those in the manufacturing industry who want to advance automation and labor-saving but find the knowledge and cost barriers too high..." Mikasa Trading will introduce solutions that are easy to implement at low cost and have high effectiveness. 【Example of Exhibited Product Lineup】 ■ Collaborative Robot Control Solutions ■ Prototype of Stop Detection Solution ■ AI Camera Solutions for Factories ■ Lenovo PCs for factory edge applications with long-term supply, high reliability, and low cost Please come and find hints to solve your on-site challenges!

FUJI is a leading company in atmospheric pressure plasma devices. In recent years, the introduction of atmospheric pressure plasma as a pre-treatment device to improve adhesive strength and quality has been progressing in manufacturing sites. FUJI's plasma device, Tough Plasma, has world-class processing capabilities and can perform continuous processing at high speeds. At this exhibition, we will showcase the latest model of the Tough Plasma series, "ATOM," which operates solely on air and electricity. Please come and see its world-class capabilities, quality, and safety monitoring features. We will also have a corner where you can experience the effects of plasma treatment firsthand with adhesive sample experiences. If you are having trouble with adhesion, please feel free to stop by our booth. During the exhibition, our engineers will be stationed at the booth. They will be happy to answer any questions you may have, from basic knowledge of plasma to the types of materials that can be processed and processing speed estimates, so please feel free to visit us. You can complete pre-registration from the link below [Details & Application].

[Instructor] Mr. Takashi Momiyama Incubation Producer, Innovation Strategy Center, Japan Research Institute, Ltd. [Key Lecture Content] From the perspective of resource security and the creation of new markets, the realization of a circular economy for EV batteries is anticipated. However, in our country, there are still numerous challenges, and the majority of EV batteries are flowing overseas along with used EVs. In recent years, protectionist policies have been promoted in various countries, such as the U.S. tariff policies and China's rare earth export regulations, and there are concerns that if our country delays its response, the outflow will accelerate further. In light of this situation, we will analyze the impact of geopolitical risks on the formation of a circular economy domestically, overview what initiatives the government, local governments, and private companies have been advancing in the country, and propose measures deemed necessary to further accelerate the formation of a circular economy. We look forward to the participation of individuals from a wide range of industries who may be involved as suppliers or users in the circular economy of EV batteries.