[1/27 Public On-Demand Webinar] Accelerating the Development and Commercialization of Biopharmaceuticals: Latest Information on Nova's Cell Culture Analysis and Automation Innovations.

Presentation of verification materials exploring the application to the evaluation of cell quality and experimental systems!

This document is a verification report that measures parameters in the culture supernatant during the maintenance culture of iPS cells and the differentiation induction process from iPS cells to dopamine-producing neural progenitor cells, exploring applications for evaluating cell quality and experimental systems. In addition to the experimental content and the composition of reagents and media, it discusses differentiation induction and maintenance culture. 【Contents】 ■ Purpose ■ Experimental Content ■ Reagents and Media Composition - Differentiation induction into neural progenitor cells - iPS cell culture ■ Discussion *For more details, please refer to the PDF document or feel free to contact us.

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Accelerating the development of the COVID-19 vaccine - Rapid simultaneous measurement of multiple items with trace samples using the automatic analysis device for cell culture environments, FLEX2.

To prevent the spread of the novel coronavirus (COVID-19), the urgent development of vaccines is required. It is said that managing the culture environment is crucial in the process of vaccine research and development involving host cell cultures. The "BioProfile" series of cell culture environment analysis devices from Nova Biomedical is widely adopted by major pharmaceutical companies and institutions in Japan and around the world for managing culture environments in vaccine research, development, and manufacturing processes. At Nova Biomedical, we hope to contribute, albeit modestly, to the development of COVID-19 vaccines by offering flexible purchasing programs tailored to your budget. For more details, please contact us through the inquiry form, and we will respond promptly. We also have materials available for cell culture analysis using our devices. 【Features】 - Monitoring the progress of cell culture - Quantification of key components in the culture medium - Early detection of abnormalities in the culture environment through regular monitoring - Capability to measure multiple items with one device, significantly reducing measurement time by consolidating the functions of multiple devices into one - Numerical backing for the timing of medium changes - Maintenance-free and sensor card-based, reducing the workload for researchers on equipment maintenance

• Other physicochemical equipment

An automatic analysis device for cell culture environments that achieves "shortened measurement time" and "significant reduction in sample volume"! All 16 items can be measured with just a small amount of sample.

The "BioProfile FLEX2" is an analytical device that utilizes micro-sensor technology. This technology allows the "BioProfile FLEX2" to achieve "reduced maintenance related to electrodes," "shortened measurement time," and "significantly reduced sample volume," making it an automatic analysis device for cell culture environments. It can measure all 16 parameters with a minimal sample volume, completing all 16 measurements in just 4 minutes and 30 seconds, or 2 minutes for individual modules. 【Features】 ■ Monitoring the progress of cell culture ■ Quantification of key components in the culture medium ■ Early detection of abnormalities through regular monitoring ■ Capability to measure multiple parameters with one device, consolidating the functions of multiple devices into one ■ Numerical backing for the timing of medium exchange *For more details, please request documentation or view the PDF data available for download.

• Other physicochemical equipment

Presentation of verification materials for iPS cell culture: Simultaneous measurement and analysis of up to 16 items in 4 minutes and 30 seconds! Strong support for improving culture efficiency.

There is data indicating that "an appropriate culture medium environment correlates with an increase in cell numbers," which necessitates the creation and adjustment of an appropriate culture medium environment to promote efficient cell culture. Are you unable to execute this due to the "time required for measurement and analysis" being a bottleneck? The cell culture environment automatic analysis device 'BioProfile FLEX2' can analyze the components of cell culture media for up to 16 items in just 4.5 minutes. It allows for rapid quantification of culture conditions such as metabolism, proliferation, and differentiation, contributing to the establishment of a culture environment aimed at mass production. ★ We are currently offering materials that investigate the correlation between changes in medium components and cell numbers in iPS cell culture. 【Features】 ■ Simultaneous analysis of up to 16 items ■ Rapid measurement time: as short as 2 minutes, up to 4 minutes and 30 seconds (depending on measurement items) ■ Capable of measuring consumption and production rates of major metabolites ■ Compatible with multiple shapes of sample containers ■ Equipped with an auto-sampling function for continuous measurement of samples *For more details, please refer to the materials available for download in PDF format.

• Other measurement, recording and measuring instruments
• Analytical Equipment and Devices

[Speaker] Naomasa Shibuya, Department Manager Data Marketing Unit, Strategy and Platform Division East Japan Railway Company Marketing Headquarters [Key Lecture Content] East Japan Railway Company announced a new group management vision, "Yusho 2034," aimed at realizing a rich life for all people by July 2025. In addition to the railway transportation business, we will further expand lifestyle service businesses (non-railway) such as station facilities, station buildings, hotels, and real estate, promoting human-centered marketing focused on our customers. To achieve this, data marketing utilizing usage history from Suica and JRE Point members is essential. It is not enough to simply implement tools or acquire analytical techniques; it is crucial to cultivate personnel who understand the business and can conduct appropriate data analysis and strategy planning. We will also introduce the development of job-type personnel in data marketing, which we began recruiting in 2024. In this lecture, I will discuss the key points for advancing data marketing within a business company, incorporating case studies.

[Lecturers] Mitsubishi UFJ Research and Consulting Co., Ltd. Consulting Business Division Sustainability Business Unit, Sustainability Strategy Department, Group 1 Senior Manager Ryo Maeda Consultant Keiro Shimada [Key Lecture Content] Towards achieving carbon neutrality by 2050, Japan is advancing the introduction of a carbon pricing system. This lecture will explain the overview of carbon pricing and the price determination mechanisms for fossil fuel levies and specific business burdens, and will discuss future price forecasts and their impact on companies. Furthermore, it will organize the latest trends in GX-ETS Phase 2 and carbon credits, as well as issues related to credit supply and demand and utilization, and will propose measures that companies need to take in light of the introduction of the carbon pricing system. [Lecture Items] 1. Trends in the carbon pricing system 2. Trends in carbon credits 3. Required responses from companies 4. Q&A / Business card exchange

We will be exhibiting at the "International Frontier Industry Messe," one of the largest comprehensive exhibitions in western Japan. September 4 (Thursday) - 5 (Friday), 2025 Kobe International Exhibition Hall 2nd floor, Hall 1, Booth Number P-74 Inside the Aioi Chamber of Commerce booth We sincerely look forward to your visit.

In recent years, the pharmaceutical and medical industries have faced urgent challenges, including the digitization of standard operating procedures (SOPs) and the strengthening of continuous education and human resource development. In this webinar, we will introduce a comprehensive system that not only streamlines operations but also consistently supports education and human resource development by integrating Agatha's SOP management cloud solution "Agatha SOP" with "Ave-TMS," a training management system provided by BIO-TREND BIOPRODUCTS, with whom Agatha has recently signed a distribution agreement. [Program] Part 1: 14:00 - 14:20 "Introduction to Agatha Solutions" Agatha Inc. Sales & Marketing Department, Quality Group Part 2: 14:20 - 15:00 "Ave-TMS Demo Presentation" BIO-TREND BIOPRODUCTS Project Manager, Choi Woo-Chun *For Q&A, please fill out the survey displayed after the webinar, and we will respond later.

[Speaker] Toshio Kawamoto, Managing Director / Head of Cross Creation Group, NTT Data Management Research Institute, Business Transformation Unit, and Co-representative of Social Innovation Alliance Japan Denmark Takaaki Sukegawa, Senior Manager [Lecture Items] 1. Competitiveness and Governance in the Post-Generative AI Era - Toshio Kawamoto [13:00 - 14:00] 1. Introduction to NTT Data Management Research Institute 2. Major countries' perspectives on AI utilization 3. Considerations for companies when building AI governance 4. Examples of AI governance construction in Japan 5. Introduction of our company's achievements in related projects 6. Q&A / Business card exchange 2. On-Site AI Risk Management in Europe ~Introduction to Trends in AI Utilization in Europe and Advanced Centralized AI Risk Management Solutions~ - Takaaki Sukegawa [14:10 - 15:10] 1. Overview of centralized AI risk management 2. Detailed approach 3. Introduction of case studies applying the approach 4. Q&A / Business card exchange