[1/27 Public On-Demand Webinar] Accelerating the Development and Commercialization of Biopharmaceuticals: Latest Information on Nova's Cell Culture Analysis and Automation Innovations.

Presentation of verification materials exploring the application to the evaluation of cell quality and experimental systems!

This document is a verification report that measures parameters in the culture supernatant during the maintenance culture of iPS cells and the differentiation induction process from iPS cells to dopamine-producing neural progenitor cells, exploring applications for evaluating cell quality and experimental systems. In addition to the experimental content and the composition of reagents and media, it discusses differentiation induction and maintenance culture. 【Contents】 ■ Purpose ■ Experimental Content ■ Reagents and Media Composition - Differentiation induction into neural progenitor cells - iPS cell culture ■ Discussion *For more details, please refer to the PDF document or feel free to contact us.

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Accelerating the development of the COVID-19 vaccine - Rapid simultaneous measurement of multiple items with trace samples using the automatic analysis device for cell culture environments, FLEX2.

To prevent the spread of the novel coronavirus (COVID-19), the urgent development of vaccines is required. It is said that managing the culture environment is crucial in the process of vaccine research and development involving host cell cultures. The "BioProfile" series of cell culture environment analysis devices from Nova Biomedical is widely adopted by major pharmaceutical companies and institutions in Japan and around the world for managing culture environments in vaccine research, development, and manufacturing processes. At Nova Biomedical, we hope to contribute, albeit modestly, to the development of COVID-19 vaccines by offering flexible purchasing programs tailored to your budget. For more details, please contact us through the inquiry form, and we will respond promptly. We also have materials available for cell culture analysis using our devices. 【Features】 - Monitoring the progress of cell culture - Quantification of key components in the culture medium - Early detection of abnormalities in the culture environment through regular monitoring - Capability to measure multiple items with one device, significantly reducing measurement time by consolidating the functions of multiple devices into one - Numerical backing for the timing of medium changes - Maintenance-free and sensor card-based, reducing the workload for researchers on equipment maintenance

• Other physicochemical equipment

An automatic analysis device for cell culture environments that achieves "shortened measurement time" and "significant reduction in sample volume"! All 16 items can be measured with just a small amount of sample.

The "BioProfile FLEX2" is an analytical device that utilizes micro-sensor technology. This technology allows the "BioProfile FLEX2" to achieve "reduced maintenance related to electrodes," "shortened measurement time," and "significantly reduced sample volume," making it an automatic analysis device for cell culture environments. It can measure all 16 parameters with a minimal sample volume, completing all 16 measurements in just 4 minutes and 30 seconds, or 2 minutes for individual modules. 【Features】 ■ Monitoring the progress of cell culture ■ Quantification of key components in the culture medium ■ Early detection of abnormalities through regular monitoring ■ Capability to measure multiple parameters with one device, consolidating the functions of multiple devices into one ■ Numerical backing for the timing of medium exchange *For more details, please request documentation or view the PDF data available for download.

• Other physicochemical equipment

Presentation of verification materials for iPS cell culture: Simultaneous measurement and analysis of up to 16 items in 4 minutes and 30 seconds! Strong support for improving culture efficiency.

There is data indicating that "an appropriate culture medium environment correlates with an increase in cell numbers," which necessitates the creation and adjustment of an appropriate culture medium environment to promote efficient cell culture. Are you unable to execute this due to the "time required for measurement and analysis" being a bottleneck? The cell culture environment automatic analysis device 'BioProfile FLEX2' can analyze the components of cell culture media for up to 16 items in just 4.5 minutes. It allows for rapid quantification of culture conditions such as metabolism, proliferation, and differentiation, contributing to the establishment of a culture environment aimed at mass production. ★ We are currently offering materials that investigate the correlation between changes in medium components and cell numbers in iPS cell culture. 【Features】 ■ Simultaneous analysis of up to 16 items ■ Rapid measurement time: as short as 2 minutes, up to 4 minutes and 30 seconds (depending on measurement items) ■ Capable of measuring consumption and production rates of major metabolites ■ Compatible with multiple shapes of sample containers ■ Equipped with an auto-sampling function for continuous measurement of samples *For more details, please refer to the materials available for download in PDF format.

• Other measurement, recording and measuring instruments
• Analytical Equipment and Devices

We will hold an online seminar as follows. The corporate perspective on the introduction of monitoring systems is changing year by year. We will explain the monitoring systems for machine tools that are currently needed, using various case studies to discuss the changes in the industry environment, what challenges customers perceive, their expectations for monitoring systems, and the effects of their implementation. This seminar will provide insights into specific approaches for your company's introduction of monitoring systems. Date and Time: February 12, 2025 (Thursday) 14:00 - 15:00 Instructor: Monitoring System Representative, ARTIS (MARPOSS Corporation Sales Development Department) Target Audience: - Customers considering the introduction of monitoring systems who want to know the specific process leading to implementation. - Customers interested in what challenges other companies have identified that led to the introduction of monitoring systems. - Customers researching the latest trends in monitoring systems for machine tools. We sincerely look forward to your participation.

We will be exhibiting at Robot Technology Japan from June 11 (Thursday) to June 13 (Saturday), 2026. Exhibits: Various hex wrenches from BONDHUS, tooling wagon from Huot, drill-specific cabinet, and webbing. If you visit Robot Technology Japan, please be sure to stop by our booth (booth number E94).

[Speaker] Kato Shun, Senior Consultant, Global Manufacturing Consulting Department, Consulting Division, Nomura Research Institute, Ltd. [Key Lecture Content] In recent years, the vibrant atmosphere at international technology exhibitions is one example of the growing expectations for the practical application of Physical AI and humanoids in the manufacturing industry. The utilization of AI technology is rapidly expanding into product development, design processes, and manufacturing sites. IT and capital investments in manufacturing are currently at a critical turning point, shifting from traditional digital transformation (DX) to the next phase based on AI and robotics. Furthermore, these environmental changes present a favorable opportunity for Japan's manufacturing sector to create new value and realize business opportunities. This lecture will present the direction of activities that Japan's manufacturing industry should undertake based on trends among advanced players in Europe and the United States.

[Speaker] Koichiro Danno, Head of the Social and Policy Design Unit, Research and Consulting Division, Japan Research Institute, Inc. [Lecture Items] May 7 (Thursday) <Session 1> Knowledge and Practices to be Aware of in Renewable Energy Power and Environmental Value Transactions 1. The Mechanism of Environmental Value Transactions in Our Country 2. International Trends in Environmental Value and Renewable Energy Transactions 3. The Mechanism of Renewable Energy Power Transactions in Our Country 4. Overview of Renewable Energy Power and Environmental Value Transaction Schemes 5. Points to Note and Business Opportunities in Each Scheme 6. Summary 7. Q&A May 13 (Wednesday) <Session 2> Knowledge and Practices to be Aware of Based on the Implementation of FIP, Corporate PPA, etc. in April 1. Overview of the FIP System 2. Business Opportunities Associated with the Transition to FIP in Other Countries 3. Corporate PPA Schemes Utilizing the FIP System 4. Self-Delivery Type Off-Site PPA 5. Requirements for Future Renewable Energy Operators 6. FIP Premium Estimation Process 7. Drastic Changes in the New Rules for FY2026 8. Summary 9. Q&A

This seminar will systematically explain the increasing importance of data integrity (DI) and CSV compliance in the field of pesticide GLP. ▶ Why is DI compliance required now? ▶ Proper data management based on the ALCOA+ principles ▶ Efficient DI measures through risk assessment ▶ DI compliance solutions and the latest analytical technologies from Agilent As a special lecturer, Dr. Kazuhiko Motoba, Executive Officer and Head of the Research Division at Japan Pesticide Co., Ltd., will be speaking. 【Event Overview】 Date: Tuesday, April 21, 2026 Time: 13:00–16:30 (Registration starts at 12:30) Venue: Bellesalle Yaesu Participation Fee: Free (Capacity: 50 people / In-person attendance only) Gain practical insights directly related to your work at the venue.