[On-Demand Seminar] Improving the Efficiency and Sustainability of Oligonucleotide Synthesis

Patented capping agent

In the process of capping for nucleic acid synthesis, it has been reported that the presence of 1,3,5-trimethylhexahydro-1,3,5-triazine in the capping agent leads to the formation of undesirable adducts. Honeywell's patent describes an invention of a nucleic acid synthesis method using a capping agent that essentially does not contain 1,3,5-trimethylhexahydro-1,3,5-triazine, proposing ultra-high purity capping agents.

• Other pharmaceutical intermediates and cosmetic ingredients

Patented BMI Activator

The Honeywell BMI activator for nucleic acid drug synthesis is patented and features a unique formulation. It is an excellent activator that does not precipitate even at low temperatures, allowing for the transportation, storage, and handling of the activator during winter. This is a proposal for cost reduction associated with the production of nucleic acid drugs.

• Other pharmaceutical intermediates and cosmetic ingredients

**Seminar Points** Improvement means changing standards for the better. There can be no improvement where there are no standards. If there are no standards, start by creating them. Standards are "rules." What to decide are "procedures," "methods," and "timing." This seminar is focused on determining "procedures" and creating "work instruction documents." **"Without standards, there is no improvement" — Learning from Toyota's teachings on documentation in the workplace** The source of Toyota's strength lies in the concepts of "improvement" and "standardization." At the core of this is a culture of making insights and skills visible in the workplace and documenting them. In other words, it is a system of knowledge transfer through documentation. Relying on the experience and intuition of veterans can be a strength in the workplace, but it also carries the risk that quality may change when people change. By ensuring that everyone performs tasks in the same way, we can achieve the same quality products (good products) in the same amount of time. First and foremost, the development of "work instruction documents" is essential. When presenting work instruction documents in video format, it is also a prerequisite that this "foundational document" is well established. *For more details, please download the PDF or contact us.*

We will be exhibiting at the "Livestock Materials EXPO" held at Makuhari Messe! We plan to showcase examples of our "Fermentation Drying Equipment for Livestock Manure," provide information on our "Composting Equipment and Deodorants," and introduce our "Subsidy Projects." Please feel free to stop by our booth. We will give a small gift to those who fill out our survey or have implemented our composting system! We look forward to meeting everyone. = Exhibition Information = Dates: October 1 (Wednesday) to October 3 (Friday), 2025, for three days from 10:00 to 17:00 Venue: Makuhari Messe, Halls 5-7, 9, and 10 2-1 Nakase, Mihama-ku, Chiba City Booth Number: Hall 9, 35-6

We would like to express our congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will be showcasing a number of products, including our new product, the Packaging Container Air Leak Test (Pin Hole Inspection) Device | MSQ-2003 series. We sincerely apologize for the inconvenience during your busy schedule, but we would like to cordially invite you to attend this event. 【 Trade Show Name 】 【 Dates 】 【 Venue/Booth Number 】

Nitto Kohki will exhibit at the "30th Mechanical Components Technology Exhibition [Tokyo]" held at Makuhari Messe Hall 5 from July 9 (Wednesday) to July 11 (Friday). [Booth Number: Hall 5 31-32] At this exhibition, we will showcase a variety of products, including the electric suction hand "e-VEE" with a built-in pump that does not require compressed air, a cordless belt sander, the electric driver "Delvo" that can be mounted on robots, and the "Flow Monitor" that allows for easy visualization of the flow of cooling water in molds and other applications.

[Speaker] Mizutani Masataka Senior Researcher Energy Comprehensive Engineering Research Institute, General Incorporated Foundation Carbon Neutral Technology Center, Power System Group [Key Lecture Content] As discussions progress towards the revision of the GHG Protocol Scope 2, elements such as "when and where the electricity was generated" are gaining attention in corporate renewable energy procurement and CO2 emissions calculations. Additionally, with the expansion of renewable energy adoption, the CO2 emission intensity of electricity has begun to fluctuate significantly depending on the time of day and region. In this lecture, we will organize topics such as hourly matching, deliverability, and standard supply services (SSS) that are being discussed in the Scope 2 revision, and introduce examples of hourly CO2 emission intensities provided both domestically and internationally. Furthermore, through analysis examples using publicly available data, such as office buildings and EV charging, we will explain what can be revealed through hourly evaluations and consider the implications and responses for future renewable energy procurement, non-fossil certificates, and PPAs.