[Sending recorded video] 4Cell Nutri-T Medium - Serum-free medium for the culture of CAR-T cells and TIL.

Excellent results and flexibility with xenofree serum-free medium for lymphocyte culture!

Cell-based immunotherapy is at the forefront of cancer treatment. The most common type of cell-based immunotherapy to date is T-cell therapy (with CAR-T and TIL being the mainstream). The cells used in immunotherapy are generally cultured in a medium supplemented with human serum. The use of serum introduces variability in the process due to individual differences among donors, leading to inconsistencies in cell growth and characteristics. By removing this serum and simplifying the process, regulatory risks are reduced, and the associated logistical burdens are alleviated. Nutri-T eliminates the need for serum by replacing its essential components with specific proteins, lipids, and other small molecules. <Product Overview> ■ Xeno-free ■ Serum-free, no serum supplementation required ■ Compliant with ISO13408 ■ For research use only ■ Developed using cells from actual cancer patients ■ Excellent results with PBMC, TIL, and CAR-T ■ Outstanding results at low initial seeding density

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An all-in-one solution designed for freezing and thawing cells, with a known chemical composition, particularly for cell therapy and clinical applications.

NutriFreez D5 Salt Based Cryopreservation Solution provides an environment that can protect cells even at ultra-low temperatures (-196°C), ensuring high survival rates, recovery rates, and performance for very delicate cells. It is manufactured under current GMP conditions and demonstrates industry-leading performance. This product is optimally formulated, containing 5% DMSO, and does not include antibiotics, antifungals, hormones, growth factors, serum, or proteins.

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A cost-effective and efficient standardized supplement designed to adhere human mesenchymal stem cells under serum-free and xeno-free culture conditions.

NutriCoat Attachment Solution is a cell adhesion substrate designed for human mesenchymal stem cells (hMSC) based on human fibrinogen, suitable for serum-free and xeno-free culture. It is optimized for human MSC derived from various tissues cultured in MSC NutriStem XF Medium. Additionally, it supports long-term culture of hMSC and the results of colony-forming unit-fibroblast (CFU-F) assays under serum-free and xeno-free culture conditions. This product is a ready-to-use solution that can be stored at room temperature, making it ideal for experiments in cell therapy research.

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Redefining the excellence of stem cells and advancing clinical applications: a complete xenofree serum-free system for the proliferation and expansion of hMSCs.

MSC NutriStem XF medium is a xeno-free medium for human mesenchymal stem cells (MSC) derived from various tissues such as bone marrow, fat, and Wharton's jelly. It supports the long-term culture of human MSC while maintaining the fibroblast-like morphology, self-renewal ability, and multipotency observed in normal MSC. MSC Attachment Solution - Xeno-free, purified human fibronectin/fibrinogen - Optimized for serum-free culture - For the proliferation and differentiation of hMSC MSC Dissociation Solution - Ready-to-use, known chemical composition - Recombinant trypsin solution NutriFreez D10 Cryopreservation Solution - Known chemical composition, animal-derived component-free, protein-free - Excellent cell adhesion and viability

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Xeno-free serum-free medium for hES cells and hiPS cells

NutriStem hPSC XF will be registered with the U.S. FDA Drug Master File (DMF)! NutriStem hPSC XF medium is a xeno-free (XF) medium optimized for the culture of human iPS/ES cells. It contains no animal-derived components and is composed entirely of human-derived proteins. NutriStem hPSC XF Medium has the capability to culture human pluripotent cells without the need for high concentrations of bFGF or other stimulatory growth factors or cytokines, enabling long-term culture while maintaining undifferentiated potential under both feeder-free (Matrigel coated) and on-feeder (MEF, HFF) conditions.

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Chuo Automobile Industry Co., Ltd. will be exhibiting at the "PV EXPO International Photovoltaic Power Generation Exhibition" held at Intex Osaka. A variety of products and technologies will be showcased, ranging from advanced solar cells to the construction, maintenance, and operation of solar power plants, with experts from around the world attending the exhibition. This event, where people and information gather "in real life" from all over the world, is an important platform to accelerate the solar power business through face-to-face interactions. We sincerely look forward to your visit.

The catabolism of branched-chain amino acids (BCAA) is important for the energy metabolism of the whole body, including skeletal muscle, and abnormalities in this process have been noted to be associated with various metabolic diseases. The BCKDH complex, which is responsible for the rate-limiting step of BCAA catabolism, is regulated by the reversible phosphorylation of the E1α subunit by BDK and PPM1K. In this seminar, using skeletal muscle cells, we will present research showing that lauric acid suppresses BCAA oxidation through an O-GlcNAc-sensitive BCKDH regulatory mechanism, and we will introduce the use of a fully automated capillary western system for the analysis of BCKDH phosphorylation and global O-GlcNAcylation.

Applied Corporation will hold a special seminar for those in charge of research and development, AI development, and AX promotion on Wednesday, November 25, 2026, at "STATION Ai" in Nagoya. With the evolution of generative AI and large-scale AI models, the computational environment required for research and development is becoming increasingly sophisticated. This seminar will introduce a high-performance computing environment that supports research and development, focusing on next-generation AI development workstations that can be utilized at the desk side. If you are considering the establishment of a new AI development environment, the introduction or upgrade of GPU workstations, or the efficiency of research and development, please take this opportunity to participate. ■ Date and Time: Wednesday, November 25, 2026, 10:30 AM - 11:30 AM ■ Details and Registration Information: https://mfrdx.applied-g.com/lp/seminar-20261125/

In recent years, the keyword "DX" has been circulating, and various companies are promoting DX initiatives. Among these initiatives, "data utilization" is considered important. Although efforts related to data utilization have increased in recent years, the reality is that few companies are fully leveraging data. To promote "data utilization," it is essential to follow the steps of collection, accumulation, analysis, and business improvement, which are the "steps to utilize data." In this seminar, we will introduce 'ASTERIA Warp,' which enables data integration without coding, 'Dr.Sum,' a DWH that builds a data utilization foundation for companies, and 'MotionBoard,' a BI dashboard that aggregates and visualizes data in real-time, leading to analytical improvements. We will present the steps to advance data utilization through these introductions. This time, you will be able to see a demonstration of the integration of the three solutions: ASTERIA Warp, Dr.Sum, and MotionBoard.

While expectations for the utilization of AI are rising, many companies face challenges such as "a lack of accumulated data for training AI," "necessary information scattered across paper and Excel," and "information fragmented across different systems." AI does not generate value on its own; it only demonstrates its effectiveness when information generated on-site is correctly collected, accumulated, and connected to the necessary departments. Therefore, to successfully utilize AI, it is essential to create an environment where data naturally gathers, flows, and can be utilized. In this seminar, as the first step in promoting DX in the manufacturing industry, we will clearly introduce the following topics with actual demonstrations: - Data collection through the digitization of on-site operations - Automatic utilization of data through system integration - Visualization and expedited decision-making using dashboards - Building a data foundation that leads to AI utilization Participants will experience "how the information input on-site is subsequently utilized" and "why data accumulation is important," while learning about the concept of "connecting DX" required in the AI era and specific ways to advance it.