<Online Seminar> Utilization of Fully Automated Capillary Western System in Analyzing the Regulatory Mechanism of BCAA Catabolism

Leo: High-throughput quantitative Western

The Leo system adopts Simple Western technology and is a high-throughput, fully automated capillary western platform. It enables fast, simple, and highly sensitive protein quantification and detection, processing up to 100 samples in a single measurement, while also expanding the experimental scale of quantitative assay design, providing measurement results in just 3 hours.

• Electrophoresis Equipment

Equipped with multiplex two-color fluorescence and automatic protein normalization function!

"Jess" is a solution that automates traditional Western blotting protein separation and immunoassay detection, eliminating labor-intensive steps that are prone to errors and mistakes. In addition to the features of Wes, it is a small high-end model equipped with multiplex two-color fluorescence and automatic protein normalization capabilities. It is a new product with fluorescence functionality. <New Feature: Capillary Reprobing> By combining the newly introduced RePlex Module with traditional reagent kits, it becomes usable! You can view examples such as "Assays for two target proteins and total protein normalization" and "Examples of signal intensity standardization based on total protein amount" from the "PDF Download." Please take a look. 【Features】 ■ Measurement with minimal sample volume (1/5 to 1/10 of the traditional amount) ■ Complete quantification, high reproducibility, and high sensitivity ■ Overwhelming processing capacity (short measurement time starting from 3 hours) ■ Elimination of human error *For more details, please refer to the PDF materials or feel free to contact us.

• Other physicochemical equipment

Provide analysis results for 24 samples in just 3 hours! Achieve picogram-level sensitivity through chemiluminescence detection and workflow automation.

"Abby" is a chemiluminescent Western protein analyzer. It automates the separation of protein sizes and immunodetection, providing analysis results for 24 samples in 3 hours. It saves time spent in the lab performing traditional Western blot procedures such as antibody addition, incubation, and washing. 【Features】 ■ Provides analysis results for 24 samples in 3 hours ■ Saves time spent in the lab performing traditional Western blot procedures ■ Achieves sensitivity at the picogram level ■ Allows for more flexible handling of valuable samples ■ Advances traditional Western blot technology *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

Chuo Automobile Industry Co., Ltd. will be exhibiting at the "PV EXPO International Photovoltaic Power Generation Exhibition" held at Intex Osaka. A variety of products and technologies will be showcased, ranging from advanced solar cells to the construction, maintenance, and operation of solar power plants, with experts from around the world attending the exhibition. This event, where people and information gather "in real life" from all over the world, is an important platform to accelerate the solar power business through face-to-face interactions. We sincerely look forward to your visit.

The catabolism of branched-chain amino acids (BCAA) is important for the energy metabolism of the whole body, including skeletal muscle, and abnormalities in this process have been noted to be associated with various metabolic diseases. The BCKDH complex, which is responsible for the rate-limiting step of BCAA catabolism, is regulated by the reversible phosphorylation of the E1α subunit by BDK and PPM1K. In this seminar, using skeletal muscle cells, we will present research showing that lauric acid suppresses BCAA oxidation through an O-GlcNAc-sensitive BCKDH regulatory mechanism, and we will introduce the use of a fully automated capillary western system for the analysis of BCKDH phosphorylation and global O-GlcNAcylation.

Applied Corporation will hold a special seminar for those in charge of research and development, AI development, and AX promotion on Wednesday, November 25, 2026, at "STATION Ai" in Nagoya. With the evolution of generative AI and large-scale AI models, the computational environment required for research and development is becoming increasingly sophisticated. This seminar will introduce a high-performance computing environment that supports research and development, focusing on next-generation AI development workstations that can be utilized at the desk side. If you are considering the establishment of a new AI development environment, the introduction or upgrade of GPU workstations, or the efficiency of research and development, please take this opportunity to participate. ■ Date and Time: Wednesday, November 25, 2026, 10:30 AM - 11:30 AM ■ Details and Registration Information: https://mfrdx.applied-g.com/lp/seminar-20261125/

In recent years, the keyword "DX" has been circulating, and various companies are promoting DX initiatives. Among these initiatives, "data utilization" is considered important. Although efforts related to data utilization have increased in recent years, the reality is that few companies are fully leveraging data. To promote "data utilization," it is essential to follow the steps of collection, accumulation, analysis, and business improvement, which are the "steps to utilize data." In this seminar, we will introduce 'ASTERIA Warp,' which enables data integration without coding, 'Dr.Sum,' a DWH that builds a data utilization foundation for companies, and 'MotionBoard,' a BI dashboard that aggregates and visualizes data in real-time, leading to analytical improvements. We will present the steps to advance data utilization through these introductions. This time, you will be able to see a demonstration of the integration of the three solutions: ASTERIA Warp, Dr.Sum, and MotionBoard.

While expectations for the utilization of AI are rising, many companies face challenges such as "a lack of accumulated data for training AI," "necessary information scattered across paper and Excel," and "information fragmented across different systems." AI does not generate value on its own; it only demonstrates its effectiveness when information generated on-site is correctly collected, accumulated, and connected to the necessary departments. Therefore, to successfully utilize AI, it is essential to create an environment where data naturally gathers, flows, and can be utilized. In this seminar, as the first step in promoting DX in the manufacturing industry, we will clearly introduce the following topics with actual demonstrations: - Data collection through the digitization of on-site operations - Automatic utilization of data through system integration - Visualization and expedited decision-making using dashboards - Building a data foundation that leads to AI utilization Participants will experience "how the information input on-site is subsequently utilized" and "why data accumulation is important," while learning about the concept of "connecting DX" required in the AI era and specific ways to advance it.