Establishment of the UpCell User Club

It is possible to collect mesenchymal stem cells, dendritic cells, macrophages, and cell sheets without using trypsin and without causing damage.

- Celsid's Technology By utilizing a unique nano-surface design, temperature-responsive polymer (PIPAAm) has been immobilized on the surface of the equipment. This allows the surface to change from hydrophobic (cell-adhesive surface) to hydrophilic (cell-releasing surface) by lowering the surface temperature around 32°C. Without using any enzymes that can damage cells, such as trypsin, intact cells can be recovered simply by setting the equipment temperature to 20-25°C and waiting for about 10-30 minutes. - Benefits 1) Easy cell recovery through temperature control. 2) Recovered cells completely retain the extracellular matrix. 3) No need for trypsin, which can harm cells. 4) Suitable for culturing tissues used in regenerative medicine research. 5) For 3D culture by stacking homo/heterogeneous cell sheets. For more details, please contact us or refer to the catalog.

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Sample presentation available! Cell sheets can be easily collected and transplanted. We use materials that are gentle on cells.

Features Dedicated cell sheet recovery support "CellShifter" for UpCell Utilizes a material with flexibility and water absorption suitable for cell detachment that could not be achieved with hydrophilic PVDF membranes or nitrocellulose membranes. This allows for the reliable and easy recovery of your precious cell sheets that have been carefully cultured with UpCell. The CellShifter, with the cell sheet adhered to it, boasts excellent ease of handling when transplanted directly to the host. Thanks to the specially treated material, there are almost no detached fibers. We guarantee maximum experimental results. Please take this opportunity to experience the results of years of material development.

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No need for trypsin! Macrophages and others are collected intact. The temperature-responsive culture equipment UpCell has "grid walls" arranged at 3mm intervals.

◆The temperature-responsive culture device UpCell for cell recovery is equipped with "grid walls" placed at 3mm intervals. ◆It has become easier to recover cultured cells in single cell/small colony form. ◆The grid wall is a new technology that prevents cells from proliferating beyond the grid by using optimized grooves on the surface of the culture dish. Cells can be recovered intact with just a short time and temperature treatment. Advantages of RepCell - It is known that trypsin significantly damages cell viability, but with RepCell, it is possible to recover cells while maintaining surface antigens and extracellular matrix. - Cell detachment using only temperature treatment The only necessary procedure for cell recovery is temperature treatment, eliminating the need for cumbersome pipetting operations associated with traditional trypsin use. For more details, please contact us or refer to the catalog.

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Complete suppression of cell adhesion in cell culture.

By applying our unique nano-surface design technology, we have fixed (covalently bonded) superhydrophilic polymers to the surfaces of our equipment. In addition to being superhydrophilic, this polymer creates a free water film. The double effect of "superhydrophilicity" and "free water" has achieved a level of low adhesion performance that far surpasses conventional low-adhesion equipment. For more details, please contact us or refer to our catalog.

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Live demonstration available! While culturing cells, we will measure the TER (transepithelial/endothelial resistance) and Ccl (capacitance) of the cell layer in real-time.

Features 1) Measurement possible while culturing cells: Long-term measurements can be conducted with the cell module placed inside the incubator. 2) Medium exchange and addition of reagents possible: The module can be removed from the incubator for operations. 3) Compatible with cell culture inserts from various manufacturers: Provides optimized medium volume for each company's inserts. 4) Each electrode is independent: Measurement of up to 24 samples is possible. (+/2) Cleaning the electrodes is easy, and inserts of different sizes can also be used. Specification of the electrodes to be measured is possible. Demonstrations are available. For more details, please contact us or refer to the catalog. You can also watch an introduction video of cellZscope on our YouTube channel.

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At our cell culture center, we conduct contract services related to cell sheet manufacturing, facility operation, and the preparation of application documents.

Features of Regenerative Medicine Contract Services 1. Development and Contract Manufacturing of Cell Sheet Products We provide contract development and manufacturing services primarily for cell sheets, commissioned by pharmaceutical companies and research institutions. Our team includes clinical culture specialists certified by the Japanese Society for Regenerative Medicine, and we offer high-quality cell sheet product development and manufacturing using experienced staff in a cell culture processing facility licensed for the production of specific cell processed products. 2. Facility Management and Application Support The "Act on Securing Safety for Regenerative Medicine" stipulates the structure, equipment, and operation of cell processing, requiring each cell culture processing facility to submit notifications and applications for permits to the Minister of Health, Labour and Welfare. At CellSeed, we assist with the notification and application documentation for the manufacture of specific cell processed products, as well as the creation of necessary operational documents. Additionally, we support the necessary administrative procedures, including the preparation of consultation materials for authorities regarding applications such as clinical trial notifications. 3. Education for Cell Culture Technicians We conduct training for cell culture technicians who have no prior experience with cell sheets, covering procedures such as cell sheet culture and detachment at our cell culture facility. For more details, please contact us or refer to our catalog.

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Live demonstration available! The difference compared to metal heating plates is clear!

It is a transparent heating element made of specially processed hard glass. It improves work efficiency in clean benches for tasks such as microscope observation and media exchange using UpCell/RepCell. Temperature settings are possible from room temperature to 50°C. It is lightweight (approximately 70g) and suitable for portability. It can also be used to cover petri dishes and multi-well plates to prevent fogging during photography. Demonstrations are available. For more details, please contact us or refer to the catalog.

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UpCell dedicated cell sheet stacking device. Stacking of sheets becomes easy. Demo unit available.

Features of CellStamp ● Utilizes the adhesion of gelatin gel and cell sheets for layering * ● Can be sterilized by autoclaving ** ● Compatible with UpCell 3.5 cm dishes and 24-well multi-wells

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To create a safe and easy-to-work civil engineering site, it is important not only to consider heavy machinery and construction methods but also to prepare the "footing" that is used every day. Muddy or uneven pathways and access roads that are difficult for vehicles to navigate can impact work efficiency and safety. Hyper CLT mats are civil engineering CLT materials that utilize wood CLT. They can be used in various locations on site, such as temporary roads, access roads, material yards, temporary parking lots, worker pathways, and around break areas. They can be laid only where needed and can be differentiated from steel plates. The 5×10 mat weighs approximately 230 kg, and the 5×20 mat weighs about 460 kg, making them lightweight and easy to install and remove even with small machinery. Additionally, they offer added value such as glare and noise reduction typical of wood, CO2 fixation, and consideration for the landscape. This is a technology registered with the Ministry of Land, Infrastructure, Transport and Tourism under NETIS, with the registration number "TH-250021-A." It is a new wooden mat that enhances the quality of the site from the ground up, addressing safety measures, environmental considerations, and creative ingenuity.

We handle primary lithium batteries manufactured by EVE Energy. In addition to Li-SOCl2 batteries (lithium thionyl chloride) and Li-MnO2 batteries (lithium manganese dioxide), we offer a wide range of products including battery capacitors (SPC) that provide instantaneous high current, as well as ER+SPC solutions that combine primary batteries and capacitors. The nominal voltage for all of them is 3.6V. 【Applications】 - Smart meters - IoT devices, security devices, etc. Since specifications vary by model number, please let us know your application and usage environment, and we will suggest a model number that meets your requirements. For specific specifications, please refer to the manufacturer's datasheet.

■Many new products introduced in this revised edition! - Added lightweight types and design rails for movable partitions - Added frame-fit doors, fire doors, and lightweight large doors for door products - Added oral sonic panels for factory partitions - Added remote cabins and creative booths for office furniture, resulting in a more comprehensive and updated general catalog. *For more details, please refer to the PDF materials or feel free to contact us.

Metal cracks are one of the concerns in equipment maintenance operations. Conventional welding methods for repairs often change the base material around the crack due to heat, leading to residual stress and deformation, which constantly carries the risk of "crack recurrence" and "secondary damage." Hinode Waterworks Co., Ltd.'s "Mechanical Stitching Method" is a new technique that allows for the repair of metal cracks without applying heat. By using special bolts and reinforcement plates, the crack is physically removed without affecting the base material at all. Repairs can be made even in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. For more details, please contact us or download the catalog.

CLT, which has been widely adopted in the construction field, is now expanding its applications into the civil engineering sector. The "Hyper CLT Mats" are civil engineering CLT products that utilize wood CLT as temporary materials. Traditionally, steel plates have been the mainstream choice for temporary roads, access routes, and heavy machinery yards. The Hyper CLT Mats introduce a new option of "wood" to that market. The 5x10 mats weigh approximately 230 kg, making them lightweight and easy to install and remove with small machinery, with a maximum capacity of 40 mats on a 10-ton truck. They also have advantages in terms of workability and transportation efficiency. Moreover, they offer added value that can only be achieved with wood, such as glare reduction, noise control, CO2 fixation, and consideration for aesthetics. This product is expected to be a new proposal for not only construction companies but also building material firms, lumber companies, and material trading companies. It is a registered technology with the Ministry of Land, Infrastructure, Transport and Tourism under NETIS, with the registration number "TH-250021-A." The use of wood is not limited to construction anymore. The utilization of Hyper CLT Mats is expanding as a new market that connects civil engineering and wood.