[Sending Recorded Video] Services Offered by Sartorius - Introduction to Cell Line Development, Cell Banking, and Various Tests.

Using Cellca cell line development, over 120 projects have been successfully completed.

Zaltrius is a top provider of cell line development services. It offers cost-effective and highly reliable technology platforms. Cellca cell line development consistently delivers clones for stable research cells that have undergone sufficient characterization. From DNA to research cell banks (RCB) in just 14 weeks, it achieves a minimum monoclonal antibody titer of 5g/L with a scalable fed-batch process.

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Conducted safety and characterization analysis tests on over 200 Chinese hamster ovary (CHO) cell bank samples.

CHO cells are the most widely used production cell lines in the pharmaceutical industry, and their safety profile has been established for over 20 years. Guidelines for the safety and characterization analysis of CHO production cell lines are harmonized with the International Conference on Harmonisation (ICH) Q5 (R1) "Virus Safety Evaluation of Biotechnology Products Derived from Cell Lines of Human or Animal Origin" and ICH Q5D "Derivation, Characterization, and Production of Cell Lines for the Manufacture of Biological Products (Biotechnology-derived Products | Biologically-derived Products)." Since 2007, Sartorius has conducted safety and characterization testing for over 200 Chinese Hamster Ovary (CHO) cell bank samples. Our researchers possess extensive knowledge and experience and will provide advice on optimal and cost-effective testing strategies that comply with chemical and regulatory requirements. We will also consider the history of the cell lines and raw materials used during bank manufacturing when proposing test packages.

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Introducing comprehensive solutions for safety testing of biological products and viral vaccines.

All biological products must undergo rigorous safety testing at both the development and manufacturing stages to confirm the characteristics of the product and host cells, as well as to ensure non-contamination. ▪ Exceptional technical expertise ▪ Rapid result delivery ▪ Extensive regulatory knowledge ▪ Enhanced quality assurance

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Integrated services with expertise and industry leadership.

【Top Service Provider】 The foundation for the approval of new biopharmaceuticals is built on a robust analytical data package that demonstrates the safety, purity, and efficacy of the product. BioOutsource's analytical testing package combines physicochemical and biological analytical methods, allowing for detailed characterization tailored to each client. 【Client Management Organization】 Projects are carried out by cross-departmental teams, and client managers provide support and advice with high transparency throughout the entire lifecycle of the client's project. 【Industry-Leading Integrated Services】 By supporting the development and characterization of biopharmaceuticals from preclinical development to commercialization, we provide services tailored to our clients' needs.

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Next-generation GMP cell banking

Thorough characterization and documentation of similar master cell banks (MCB) and working cell banks (WCB) are crucial elements that lead to risk reduction and ensure the safety and product quality of all biologically derived products. An experienced team is leveraging CRO expertise to expand services such as cell bank manufacturing. ▪ Manufacturing in a closed system ▪ Quality assurance ▪ Integration into cell line development and biosafety services ▪ For your applications: from mAbs to vaccines

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Comprehensively supporting the early development of biopharmaceuticals on an independent platform.

Physical and Chemical, as well as Biological Equivalence of Biosimilars | Similarity Assessment 【Expertise】 Industry-leading experience with over 12 biosimilar molecules and more than 30 biosimilar development companies 【Speed to Market】 Cost-effective results guaranteed through a comprehensive lineup of ready-made assays for the characterization and equivalence | similarity assessment of biosimilars 【Higher Quality Assurance】 Providing the necessary data for submission at the time of application, backed by exceptional regulatory and industry insights

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[Lecture Topics] 1. Trends in Policies for Decarbonization of Housing and Buildings Tetsuya Hirayama, Deputy Director, Housing Bureau, Ministry of Land, Infrastructure, Transport and Tourism (in charge of architectural planning) 2. Construction Circular Economy - Expanding Horizontal Recycling for Achieving Sustainable Construction Takahiro Moritomi, Analyst, Social Infrastructure Team, Next Generation Infrastructure and Services Office, Industry Research Department, Mizuho Bank, Ltd. 3. Beyond "Scrap and Build" Aiming for the Realization of "Circular Design Build®" Shoichi Fukui, Senior Chief Expert, Sustainability Promotion Department, Management Planning Office, Takenaka Corporation

[Instructor] Attorney Kurato Suzuki, Irokawa Law Office [Key Lecture Content] Due to the amendments to the Comprehensive Promotion Law for Labor Policies, starting from October 1, 2026, employers will be required to take necessary measures in employment management regarding customer harassment (Kasu Hara) and sexual harassment against job seekers (Job Hunting Sexual Harassment). In line with this, companies will need to prepare for practical implementation before the enforcement date, based on the guidelines published by the Ministry of Health, Labour and Welfare. This includes developing internal regulations, establishing consultation and response systems, raising awareness within the company, and determining judgment and response methods on-site. This seminar will organize the setting of job hunting rules related to job hunting sexual harassment, internal awareness, and key points for regulatory development. It will also explain the distinction between legitimate complaints and customer harassment, judgment, documentation, and response on-site, the establishment of a company-wide system, regulatory development considering dispute risks, and points that are easily overlooked. The Human Resources, Labor, Legal, and Compliance departments will systematically organize the response matters that need to be confirmed in preparation for the enforcement on October 1, 2026, from the perspectives of guideline compliance and on-site operations. [Lecture Items] 1. Job Hunting Sexual Harassment 2. Customer Harassment 3. Q&A

[Speaker] Mr. Itsuki Wakayama, Project General Manager, Technology Promotion Unit, Low Carbon Solutions Division, INPEX Corporation [Key Lecture Content] The greatest advantage of synthetic methane production through CO2 methanation technology is that it enables decarbonization without significant additions or modifications to all existing natural gas and city gas infrastructure. At INPEX, after two NEDO commissioned projects, we have been conducting the development of practical application technology with a capacity of 400 Nm3-CO2/h, one of the largest in the world, as a subsidized project by NEDO since the fiscal year 2021. By the fiscal year 2025, we aim to achieve the injection of synthetic methane produced during the demonstration operation of the test facility. This presentation will provide detailed information on the results of the NEDO project for the fiscal year 2025, including the current status of the latest test facilities. [Presentation Items] 1. INPEX's efforts towards net zero by 2050 2. Policy trends related to CO2 methanation 3. Challenges of CO2 methanation 4. Results of the NEDO practical application technology development project with a capacity of 400 Nm3-CO2/h for the fiscal year 2025 5. Future commercialization prospects and challenges 6. Q&A / Business card exchange

[Speaker] Mr. Satoru Shimizu, President and CEO of Okunote Inc. [Key Lecture Content] Generative AI is not a "magic wand," but a "mirror" that reflects the questions of the user. In this lecture, based on my book "The 'Super' Planning Techniques Practiced by Competition Disruptors: Seven Creative Steps to Lead Winning Strategies with the 'Art of Questioning'," I will explain how to overcome the challenges of proposals being rejected, not moving forward within the company, and not being executed on-site through interactions with AI. I will introduce the entire process of planning, linking it with AI utilization, from question design to hypothesis destruction, structuring materials from the decision-maker's perspective, forming internal consensus, managing execution, and turning reflections into assets. In the latter part of the workshop (exclusive to on-site participants), you will actually formulate questions and refine your dialogue with AI, taking home usable "art of questioning" techniques for tomorrow. [Lecture Items] 1. Orientation: AI is a "mirror," not a "magic wand." 2. Enhancing the precision of planning through "question design" and "hypothesis destruction." 3. Structuring materials from the decision-maker's perspective to create "acceptable" proposals. 4. Forming consensus that transcends internal barriers. 5. Mechanisms that prevent execution from stopping and turning experiences into assets through reflection. 6. Habitualizing AI as a "partner" and the roles humans will take on in the AI era.

【Exhibition Overview】 A collection of products related to data centers, which are at the core of AI infrastructure, gathered in one place.