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  6. Cryo-SEM analysis: Evaluation of the dispersion state of microparticles in liquid.

Cryo-SEM analysis: Evaluation of the dispersion state of microparticles in liquid.

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last updated:Apr 02, 2026

一般財団法人材料科学技術振興財団 MST
一般財団法人材料科学技術振興財団 MST
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By rapid freezing and SEM observation, the dispersion of particles was confirmed through images! ★Data displayed at the 25th Interphex Japan★

When evaluating the particle size and structure of fine particles used in a liquid dispersion, it is common practice to dry the liquid to extract the fine particles as a powder and measure them using an electron microscope. However, this measurement method is not suitable for investigating how the particles are dispersed, as changes in the dispersion state and deformation of the particles can occur due to drying. In MST, to directly assess how fine particles are dispersed within a liquid sample, cryo-processing followed by SEM analysis (cryo-SEM analysis) is performed for evaluation.

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Cryo-SEM analysis: Evaluation of the dispersion state of microparticles in liquid.

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The liquid sample is rapidly frozen by immersing it in liquid nitrogen, and FIB processing and SEM analysis are conducted within the same device while maintaining the cooling state. Detailed data will be exhibited at the 25th Interphex Japan! Our specialized technical staff will provide thorough explanations at the booth.

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It varies depending on the subject of the analysis. Please feel free to contact us.

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Applications/Examples of results

Evaluation of liquid foundation with micro-particles.

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Notice of Participation in the 25th INTERPHEX Japan

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Interfex Japan is an international specialized exhibition where all the equipment, systems, and technologies necessary for the manufacturing and research and development of pharmaceuticals, cosmetics, and detergents are showcased together. MST will propose solutions using analysis in the research and development and manufacturing sites of pharmaceuticals and cosmetics. We sincerely look forward to your visit. ● Event Dates June 27 (Wednesday) to June 29 (Friday), 2012, 10:00 AM to 6:00 PM [Only on the final day, June 29 (Friday), it will end at 5:00 PM] ● Venue and Booth Tokyo Big Sight, East Hall 5, Booth 45-18 ● Exhibition Content We will introduce analysis case studies on panels. Specialized analysis staff will be stationed at the booth to provide consultations on analysis and introduce methods. 【Main Content】 - Evaluation of the structure and dispersion of fine particles in liquid using Cryo-SEM - Cross-sectional observation of enamel prisms in teeth using TEM - Analysis of odor components using GC/MS - Evaluation of the distribution of components in hair using TOF-SIMS - Radiation measurement We sincerely look forward to your visit.

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一般財団法人材料科学技術振興財団 MST

一般財団法人材料科学技術振興財団 MST

Testing, Analysis and Measurement

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MST is a foundation that provides contract analysis services. We possess various analytical instruments such as TEM, SIMS, and XRD to meet your analysis needs. Our knowledgeable sales representatives will propose appropriate analysis plans. We are also available for consultations at your company, of course. We have obtained ISO 9001 and ISO 27001 certifications. Please feel free to consult us for product development, identifying causes of defects, and patent investigations! MST will guide you to solutions for your "troubles"!

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